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Transcriptional Regulation

Inducible Processing of Interferon Regulatory Factor-2

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Pages 3325-3336 | Received 13 Mar 1992, Accepted 04 May 1992, Published online: 01 Apr 2023

REFERENCES

  • Ausubel, F. M., R. Brent, R. E. Kingston, D. M. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1988. Current protocols in molecular biology. Wiley Interscience, New York.
  • Baeuerle, P. A., and D. Baltimore. 1988. Activation of DNA binding activity in an apparently cytoplasmic precursor of the NF-κB transcription factor. Cell 53:211–217.
  • Brand, A. H., L. Breeden, J. Abraham, R. Sternglanz, and K. Nasmyth. 1985. Characterization of a “silencer” in yeast: a DNA sequence with properties opposite to those of a transcriptional enhancer. Cell 41:41–46.
  • Chen, C. A., and H. Okayama. 1988. Calcium phosphate- mediated gene transfer: a highly efficient transfection system for stably transforming cells with plasmid DNA. BioTechniques 6:632–638.
  • DeMaeyer, E., and J. DeMaeyer-Guignard. 1988. Interferons and other regulatory cytokines. John Wiley & Sons, Inc., New York.
  • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by DNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Du, W., and T. Maniatis. 1992. An ATF/CREB element is required for virus induction of the human interferon-β gene. Proc. Natl. Acad. Sci. USA 89:2150–2154.
  • Enoch, T., K. Zinn, and T. Maniatis. 1986. Activation of the human β-interferon gene requires an interferon-inducible factor. Mol. Cell. Biol. 6:801–810.
  • Fan, C.-M., and T. Maniatis. 1989. Two different virus-inducible elements are required for human β-interferon gene regulation. EMBO J. 8:101–110.
  • Fan, C.-M., and T. Maniatis. 1991. Generation of p50 subunit of NF-κB by processing of p105 through an ATP-dependent pathway. Nature (London) 354:395–398.
  • Fried, M., and D. M. Crothers. 1981. Equilibria and kinetics of lac repressor-operator interactions by polyacrylamide gel electrophoresis. Nucleic Acids Res. 9:6505–6525.
  • Fujita, T., Y. Kimura, M. Miyamoto, E. L. Barsoumian, and T. Taniguchi. 1989. Induction of endogenous IFN-α and IFN-β genes by regulatory transcription factor, IRF-1. Nature (London) 337:270–272.
  • Fujita, T., M. Miyamoto, Y. Kimura, J. Hammer, and T. Taniguchi. 1989. Involvement of a cis-element that binds an H2TF-1/NF-κB like factor(s) in the virus-induced interferon-β gene expression. Nucleic Acids Res. 17:3335–3346.
  • Fujita, T., S. Ohno, H. Yasumitsu, and T. Taniguchi. 1985. Delimitation and properties of DNA sequences required for the regulated expression of human interferon-β gene. Cell 41:489–496.
  • Fujita, T., L. F. L. Reis, N. Watanabe, Y. Kimura, T. Taniguchi, and J. Vilcek. 1989. Induction of the transcription factor IRF-1 and interferon-β mRNAs by cytokines and activators of second messenger pathways. Proc. Natl. Acad. Sci. USA 86:9936–9940.
  • Fujita, T., J. Sakakibara, Y. Sudo, M. Miyamoto, Y. Kimura, and T. Taniguchi. 1988. Evidence for a nuclear factor(s), IRF-1, mediating induction and silencing properties to human IFN-β gene regulatory elements. EMBO J. 7:3397–3405.
  • Fujita, T., H. Shibuya, H. Hotta, K. Yamanishi, and T. Taniguchi. 1987. Interferon-β gene regulation: tandemly repeated sequences of a synthetic 6 bp oligomer function as a virusinducible enhancer. Cell 49:357–367.
  • Goodbourn, S., K. Zinn, and T. Maniatis. 1985. Human β-interferon gene expression is regulated by an inducible enhancer element. Cell 41:509–520.
  • Goodbourn, S. E. Y., and T. Maniatis. 1988. Overlapping positive and negative regulatory domains of the human β-interferon gene. Proc. Natl. Acad. Sci. USA 85:1447–1451.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Harada, H., T. Fujita, M. Miyamoto, Y. Kimura, M. Maruyama, A. Furia, T. Miyata, and T. Taniguchi. 1989. Structurally similar but functionally distinct factors, IRF-1 and IRF-2, bind to the same regulatory elements of IFN and IFN-inducible genes. Cell 58:729–739.
  • Harada, H., K. Willison, J. Sakakibara, M. Miyamoto, T. Fujita, and T. Taniguchi. 1990. Absence of the type I IFN system in EC cells: transcriptional activator (IRF-1) and repressor (IRF-2)genes are developmentally regulated. Cell 63:303–312.
  • Hiscott, J., D. Alper, L. Cohen, J. F. Leblanc, L. Sportza, A. Wong, and S. Xanthoudakis. 1989. Induction of human interferon gene expression is associated with a nuclear factor that interacts with the NF-κB site of the human immunodeficiency virus enhancer. J. Virol. 63:2557–2566.
  • Itoh, S., H. Harada, T. Fujita, T. Mimura, and T. Taniguchi. 1989. Sequence of a cDNA coding for human IRF-2. Nucleic Acids Res. 17:8372.
  • Kadonaga, J. T., and R. Tjian. 1986. Affinity purification of sequence-specific DNA binding proteins. Proc. Natl. Acad. Sci. USA 83:5889–5893.
  • Keller, A. D., and T. Maniatis. 1988. Identification of an inducible factor that binds to a positive regulatory element of the human β-interferon gene. Proc. Natl. Acad. Sci. USA 85:3309–3313.
  • Keller, A. D., and T. Maniatis. 1991. Identification and characterization of a novel repressor of β-interferon gene expression. Genes Dev. 5:868–879.
  • Kuhl, D., J. de la Fuente, M. Chaturvedi, S. Parimoo, J. Ryals, F. Meyer, and C. Weissmann. 1987. Reversible silencing of enhancers by sequences derived from the human IFN-α promoter. Cell 50:1057–1069.
  • Leblanc, J.-F., L. Cohen, M. Rodrigues, and J. Hiscott. 1990. Synergism between distinct enhanson domains in viral induction of the human beta interferon gene. Mol. Cell. Biol. 10:3987–3993.
  • Lenardo, M. J., C.-M. Fan, T. Maniatis, and D. Baltimore. 1989. The involvement of NF-κB in β-interferon gene regulation reveals its role as widely inducible mediator of signal transduction. Cell 57:287–294.
  • Levine, M., and J. L. Manley. 1989. Transcriptional repression of eukaryotic promoters. Cell 59:405–408.
  • MacDonald, N. J., D. Kuhl, D. Maguire, D. Naf, P. Gallant, A. Groswamy, H. Hug, H. Bueler, M. Chaturvedi, J. de la Fuente, H. Ruffner, F. Meyer, and C. Weissmann. 1990. Different pathways mediate virus inducibility of the human IFN-α1 and IFN-β genes. Cell 60:767–779.
  • MacGregor, G. R., and C. T. Caskey. 1989. Construction of plasmids that express E. coli beta-galactosidase in mammalian cells. Nucleic Acids Res. 17:2365.
  • Maniatis, T., L.-A. Whittemore, W. Du, C.-M. Fan, A. D. Keller, V. J. Palombella, and D. N. Thanos. Positive and negative control of human interferon-β gene expression. In S. McKnight and K. Yamamoto (ed.), Transcriptional regulation, in press. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Maroteaux, L., L. Chen, S. Mitrani-Rosenbaum, P. M. Howley, and M. Revel. 1983. Cycloheximide induces expression of the human interferon β1 gene in mouse cells transformed by bovine papillomavirus-interferon β1 recombinants. J. Virol. 47:89–95.
  • Miyamoto, M., T. Fujita, Y. Kimura, M. Maruyama, H. Harada, Y. Sudo, T. Miyata, and T. Taniguchi. 1988. Regulated expression of a gene encoding a nuclear factor, IRF-1, that specifically binds to IFN-β gene regulatory element. Cell 54:903–913.
  • Munro, S., and H. R. B. Pelham. 1987. A c-terminal signal prevents secretion of luminal ER proteins. Cell 48:899–907.
  • Naf, D., S. E. Hardin, and C. Weissmann. 1991. Multimerization of AAGTGA and GAAAGT generates sequences that mediate virus inducibility by mimicking an interferon promoter element. Proc. Natl. Acad. Sci. USA 88:1369–1373.
  • Ogawa, T. 1990. Regulation in repressor inactivation by RecA protein. Adv. Biophys. 26:33–49.
  • Palombella, V., A. Keller, and T. Maniatis. Unpublished data.
  • Palombella, V., and T. Maniatis. Unpublished data.
  • Palombella, V., D. Thanos, L. Whittemore, and T. Maniatis. Unpublished data.
  • Pine, R., T. Decker, D. S. Kessler, D. E. Levy, and J. E. Darnell, Jr. 1990. Purification and cloning of interferon-stimulated gene factor 2 (ISGF2): ISGF2 (IRF-1) can bind to the promoters of both beta interferon- and interferon-stimulated genes but is not a primary transcriptional activator of either. Mol. Cell. Biol. 10:2448–2457.
  • Raj, N. B. K., J. Engelhardt, W.-C. Au, D. E. Levy, and P. M. Pitha. 1989. Virus infection and interferon can activate gene expression through a single synthetic element, but endogenous genes show distinct regulation. J. Biol. Chem. 264:16658–16666.
  • Raj, N. B. K., and P. M. Pitha. 1983. Two levels of regulation of β-interferon gene expression in human cells. Proc. Natl. Acad. Sci. USA 80:3923–3927.
  • Reis, L. F. L., H. Harada, J. D. Wolchok, T. Taniguchi, and J. Vilcek. 1992. Critical role of a common transcription factor, IRF-1, in the regulation of IFN-β and IFN-inducible genes. EMBO J. 11:185–193.
  • Renkawitz, R. 1990. Transcriptional repression in eukaryotes. Trends Genet. 6:192–196.
  • Riviere, Y., V. Blank, P. Kourilsky, and A. Israel. 1991. Processing of the precursor of NF-κB by the HIV-1 protease during acute infection. Nature (London) 350:625–626.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Sehgal, P. B., B. Dobberstein, and I. Tamm. 1977. Interferon message RNA content of human fibroblasts during induction, shutoff, and superinduction of interferon production. Proc. Natl. Acad. Sci. USA 74:3409–3413.
  • Sehgal, P. B., and I. Tamm. 1979. Two mechanisms contribute to the superinduction of poly(I)-poly(C)-induced human fibroblast interferon production. Virology 92:240–244.
  • Sen, R., and D. Baltimore. 1986. Induction of κ immunoglobulin enhancer binding protein NF-κB by a posttranslational mechanism. Cell 47:921–928.
  • Vilcek, J. 1990. Interferons, p. 1–38. In M. B. Sporn and A. B. Roberts (ed.), Handbook of experimental pharmacology, vol. 95/II. Peptide growth factors and their receptors. SpringerVerlag, Berlin.
  • Visvanathan, K. V., and S. Goodbourn. 1989. Double-stranded RNA activates binding of NF-κB to an inducible element in the human β-interferon promoter. EMBO J. 8:1129–1138.
  • Watanabe, N., J. Sakakibara, A. G. Hovanessian, T. Taniguchi, and T. Fujita. 1991. Activation of IFN-β element by IRF-1 requires a post-translational event in addition to IRF-1 synthesis. Nucleic Acids Res. 19:4421–4428.
  • Weinstock, G. M., and K. McEntee. 1981. RecA protein-dependent proteolysis of bacteriophage lambda repressor. Characterization of the reaction and stimulation by DNA binding proteins. J. Biol. Chem. 256:10883–10888.
  • Whiteside, S. T., K. V. Visvanathan, and S. Goodbourn. 1992. Identification of novel factors that bind to the PRDI region of the human β-interferon promoter. Nucleic Acids Res. 20:1531–1538.
  • Whittemore, L.-A., and T. Maniatis. 1990. Postinduction turnoff of beta-interferon gene expression. Mol. Cell. Biol. 10:1329–1337.
  • Whittemore, L.-A., and T. Maniatis. 1990. Postinduction repression of the β-interferon gene is mediated through two positive regulatory domains. Proc. Natl. Acad. Sci. USA 87:7799–7803.
  • Whittemore, L.-A., and T. Maniatis. Unpublished data.
  • Xanthoudakis, S., L. Cohen, and J. Hiscott. 1989. Multiple protein-DNA interactions within the human interferon-β regulatory element. J. Biol. Chem. 264:1139–1145.
  • Yang, Y.-C., A. B. Ciarletta, P. A. Temple, M. P. Chung, S. Kovacic, J. S. Witek-Giannotti, A. C. Leary, R. Kritz, R. E. Donahue, G. G. Wong, and S. C. Clark. 1986. Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3. Cell 47:310.
  • Zinn, K., D. DiMaio, and T. Maniatis. 1983. Identification of two distinct regulatory regions adjacent to the human β-interferon gene. Cell 34:865–879.

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