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DNA Dynamics and Chromosome Structure

An Abundant High-Mobility-Group-Like Protein Is Targeted to Micronuclei in a Cell Cycle-Dependent and Developmentally Regulated Fashion in Tetrahymena thermophila

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Pages 163-173 | Received 11 Aug 1996, Accepted 15 Oct 1992, Published online: 01 Apr 2023

REFERENCES

  • Allis, C. D., Μ. Colavito-Shepanski, and Μ. A. Gorovsky. 1987. Scheduled and unscheduled DNA synthesis during development in conjugating Tetrahymena. Dev. Biol. 124:469–480.
  • Allis, C. D., and D. K. Dennison. 1982. Identification and purification of young macronuclear anlagen from conjugating cells of Tetrahymena thermophila. Dev. Biol. 93:519–533.
  • Allis, C. D., and J. C. Wiggins. 1984. Histone rearrangements accompany nuclear differentiation and dedifferentiation in Tet- rahymena. Dev. Biol. 101:282–294.
  • Allis, C. D., Y. S. Ziegler, Μ. A. Gorovsky, and J. B. Olmsted. 1982. A conserved histone variant enriched in nucleoli of mammalian cells. Cell 31:131–136.
  • Bruns, P. J., and T. B. Brussard. 1974. Pair formation in Tetrahymena pyriformis, an inducible developmental system. J. Exp. Zool. 188:337–344.
  • Bustin, Μ., D. A. Lehn, and D. Landsman. 1990. Structural features of the HMG chromosomal proteins and their genes. Biochim. Biophis. Acta 1049:231–243.
  • Diffley, J. X., and B. Stillman. 1991. A close relative of the nuclear, chromosomal high-mobility group protein HMG 1 in yeast mitochondria. Proc. Natl. Acad. Sci. USA 88:7864–7868.
  • Diffley, J. X., and B. Stillman. 1992. DNA binding properties of an HMG 1-related protein from yeast mitochondria. J. Biol. Chem. 267:3368–3374.
  • Fisher, R. P., T. Lisowsky, Μ. A. Parisi, and D∙ A. Clayton. 1992. DNA wrapping and bending by a mitochondrial high mobility group-like transcriptional activator protein. J. Biol. Chem. 267:3358–3367.
  • Giese, K., J. Cox, and R. Grosschedl. 1992. The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures. Cell 69:185–195.
  • Gorovsky, Μ. A., M.-C. Yao, J. B. Keevert, and G. L. Pleger. 1975. Isolation of micro- and macronuclei of Tetrahymena pyriformis. Methods Cell Biol. 9:311–327.
  • Hamana, K., and K. Iwai. 1979. High mobility group nonhistone chromosomal proteins also exist in Tetrahymena. J. Biochem. (Tokyo) 86:789–794.
  • Jackson, V. 1987. Deposition of newly synthesized histones: new histones H2A and H2B do not deposit in the same nucleosome with new histones H3 and H4. Biochemistry 26:2315–2325.
  • Johns, E. W. 1982. History, definitions and problems, p. 1–9. In E. W. Johns (ed.), The HMG chromosomal proteins. Academic Press, London.
  • Kolodrubetz, D., and A. Burgum. 1990. Duplicated NHP6 genes of Saccharomyces cerevisiae encode proteins homologous to bovine high mobility group protein 1. J. Biol. Chem. 265:3234–3239.
  • Levy-Wilson, B., Μ. S. Denker, and E. Ito. 1983. Isolation, characterization, and postsynthetic modifications of Tetrahymena high mobility group proteins. Biochemistry 22:1715–1721.
  • Lilley, D. Μ. 1992. HMG has DNA wrapped up. Nature (London) 357:282–283.
  • Lin, R., J. W. Leone, R. G. Cook, and C. D. Allis. 1989. Antibodies specific to acetylated histones document the existence of deposition- and transcription-related histone acetylation in Tetrahymena. J. Cell Biol. 108:1577–1588.
  • Martindale, D. W., C. D. Allis, and P. J. Bruns. 1985. RNA and protein synthesis during meiotic prophase in Tetrahymena thermophila. J. Protozool. 32:644–649.
  • Ner, S. S. 1992. HMGs everywhere: a new and diverse class of DNA-binding proteins is identified by a common sequence motif. Curr. Biol. 4:208–210.
  • Schulman, I. G., R. G. Cook, R. Richman, and C. D. Allis. 1987. Tetrahymena contains two distinct and unusual high mobility group (HMG)-Iike proteins. J. Cell Biol. 104:1485–1494.
  • Schulman, I. G., T. Wang, and C. D. Allis. Unpublished observations.
  • Schulman, I. G., T. Wang, L. A. Stargell, Μ. A. Gorovsky, and C. D. Allis. 1991. Cell-cell interactions trigger the rapid induction of a specific high mobility group-like protein during early stages of conjugation in Tetrahymena. Dev. Biol. 143:248–257.
  • Schulman, I. G., T. Wang, Μ. Wu, J. K. Bowen, R. G. Cook, Μ. A. Gorovsky, and C. D. Allis. 1991. Macronuclei and micronuclei in Tetrahymena thermophila contain high-mobility- group-like chromosomal proteins containing a highly conserved eleven-amino-acid putative DNA-binding sequence. Mol. Cell. Biol. 11:166–174.
  • Sugai, T., and K. Hiwatashi. 1974. Cytological and autoradiographic studies of the micronucleus at meiotic prophase in Tetrahymena pyriformis. J. Protozool. 21:542–548.
  • Sweet, Μ., and C. D. Allis. Unpublished data.
  • van Holde, K. E. 1988. Chromatin. Springer-Verlag New York, Inc., New York.
  • Wagner, C. R., K. Hamana, and S. C. R. Elgin. 1992. A high-mobility-group protein and its cDNAs from Drosophila melanogaster. Mol. Cell. Biol. 12:1915–1923.
  • Wenkert, D., and C. D. Allis. 1984. Timing of the appearance of the macronuclear-specific histone variant hvl and gene expression in developing new macronuclei of Tetrahymena thermophila. J. Cell Biol. 98:2107–2117.
  • White, E. Μ., C. D. Allis, D. S. Goldfarb, A. Srivastva, J. W. Weir, and Μ. A. Gorovsky. 1987. Nucleus-specific and temporally restricted localization of proteins in Tetrahymena macronuclei and micronuclei. J. Cell Biol. 109:1983–1992.
  • White, E. Μ., and Μ. A. Gorovsky. 1988. Localization and expression of mRNA for a macronuclear-specific histone H2A variant (hv1) during the cell cycle and conjugation of Tetrahy- mena thermophila. Mol. Cell. Biol. 8:4780–4786.
  • Wu, Μ., C. D. Auis, and M. A. Gorovsky. 1988. Cell-cycle regulation as a mechanism for targeting proteins to specific DNA sequences in Tetrahymena thermophila. Proc. Natl. Acad. Sci. USA 85:2205–2209.
  • Yu, S.-M., S. Horowitz, and M∙ A. Gorovsky. 1987. A novel approach for Studing gene expression in the cell cycle reveals coordinate and independent regulation of members of the H4 multigene family in cycling and in nongrowing Tetrahymena. Genes Dev. 1:683–692.

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