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Cell Growth and Development

Cell Cycle Analysis of p53-Induced Cell Death in Murine Erythroleukemia Cells

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Pages 711-719 | Received 04 Jun 1992, Accepted 15 Sep 1992, Published online: 01 Apr 2023

REFERENCES

  • Baker, J. J., K. Markowitz, E. R. Fearon, J. K. V Willson, and B. Vogelstein. 1990. Suppression of human colorectal carcinoma cell growth by wild-type p53. Science 249:1912–1915.
  • Ben David, Y., E. Giddens, and A. Bernstein. 1990. Identification and mapping of a common proviral integration site Fli-1 in erythroleukemia cells induced by Friend murine leukemia virus. Proc. Natl. Acad. Sci. USA 87:1332–1336.
  • Bischoff, J. R., P. N. Friedman, D. A. Marshak, C. Prives, and D. Beach. 1990. Human p53 is phosphorylated by p60-cdc2 and cyclin B-cdc2. Proc. Natl. Acad. Sci. USA 87:4766–4770.
  • Buchkovich, K., L. A. Duffy, and E. Harlow. 1989. The retinoblastoma protein is phosphorylated during specific phases of the cell cycle. Cell 58:1097–1105.
  • Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156–159.
  • Clarke, Μ. F., J. F. Kukowska-Latallo, E. Westin, Μ. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol. Cell. Biol. 8:884–892.
  • Coppola, J. A., and Μ. D. Cole. 1986. Constitutive c-myc oncogene expression blocks mouse erythroleukemia cell differentiation but not commitment. Nature (London) 320:760–763.
  • Danish, R., O. El-Awar, B. L. Weber, J. Langmore, L. A. Turka, J. J. Ryan, and Μ. F. Clarke. 1992. c-myb effects on kinetic events during MEL cell differentiation. Oncogene 7:901–907.
  • Danova, M., Μ. Giordano, G. Mazzini, and A. Riccardi. 1990. Expression of p53 protein during the cell cycle measured by flow cytometry in human leukemia. Leuk. Res. 14:417–422.
  • Decaprio, J. A., J. W. Ludlow, D. Lynch, Y. Furukawa, J. Griffin, H. Piwnica-Worms, C.-M. Huang, and D. Μ. Livingston. 1989. The product of the retinoblastoma susceptibility gene has properties of a cell cycle regulatory element. Cell 58:1085–1095.
  • Diller, L., J. Kassel, C. E. Nelson, Μ. A. Gryka, G. Litwak, Μ. Gebhardt, B. Bressac, Μ. Ozturk, S. J. Baker, B. Vogelstein, and S. H. Friend. 1990. p53 functions as a cell cycle control protein in osteosarcomas. Mol. Cell. Biol. 10:5772–5781.
  • Dmitrovsky, E., W. Μ. Kuehl, G. F. Hollis, I. R. Kirsch, T. P. Bender, and S. Segal. 1986. Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukemia cell line. Nature (London) 322:748–750.
  • Donehower, L. A., Μ. Harvey, B. L. Slagle, Μ. J. McArthur, C. A. Montgomery, Jr., J. S. Butel, and A. Bradley. 1992. Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumors. Nature (London) 356:215–221.
  • Duvall, E., and A. H. Wyllie. 1986. Death and the cell. Immunol. Today 7:115–119.
  • Eliyahu, D., D. Michalovitz, and Μ. Oren. 1985. Overproduction of p53 antigen makes established cells highly tumorigenic. Nature (London) 316:158–160.
  • Evan, G. I., A. H. Wyllie, C. S. Gilbert, T. D. Littlewood, H. Land, Μ. Brooks, C. Μ. Waters, L. Z. Penn, and D. C. Hancock. 1992. Induction of apoptosis in fibroblasts by c-myc protein. Cell 69:119–128.
  • Friend, S. H., R. Bernards, S. Rogelj, R. A. Weinberg, J. Μ. Rapaport, D. Μ. Albert, and T. P. Dryja. 1986. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma. Nature (London) 323:643–646.
  • Ginsburg, D., D. Michael-Michalovitz, D. Ginsburg, and Μ. Oren. 1991. Induction of growth arrest by a temperaturesensitive p53 mutant is correlated with increased nuclear localization and decreased stability of the protein. Mol. Cell. Biol. 11:582–585.
  • Gusella, J., R. Geller, B. Clark, V. Weeks, and D. Housman. 1976. Commitment to erythroid differentiation by Friend erythroleukemia cells: a stochastic analysis. Cell 9:221–229.
  • Harlow, E., L. V. Crawford, D. C. Pim, and N. Μ. Williamson. 1981. Monoclonal antibodies specific for simian virus 40 tumor antigens. J. Virol. 39:861–869.
  • Heintz, N. H., and J. L. Hamlin. 1982. An amplified chromosomal sequence that includes the gene for dihydrofolate reductase initiates replication within specific restriction fragments. Proc. Natl. Acad. Sci. USA 79:4083–4087.
  • Johnson, P., D. Gray, Μ. Mowat, and S. Benchimol. 1991. Expression of wild-type p53 is not compatible with continued growth of p53-negative tumor cells. Mol. Cell. Biol. 11:1–11.
  • Kastan, Μ. B., A. I. Radin, S. J. Kuerbitz, O. Onyekwere, C. A. Wolkow, C. I. Civin, K. D. Stone, T. Woo, Y. Ravinchranath, and R. W. Craig. 1991. Levels of p53 protein increase with maturation in human hematopoietic cells. Cancer Res. 51:4279–4286.
  • Keuhl, W. Μ., T. P. Bender, J. Stafford, D. McClinton, S. Segal, and E. Dmitrovslty. 1988. Expression and function of c-myb oncogene during hematopoietic differentiation. Curr. Top. Microbiol. Immunol. 141:318–323.
  • Khochbin, S., A. Chabanas, and J. J. Lawrence. 1988. Early events in murine erythroleukemia cells induced to differentiate: variation of the cell cycle parameters in relation to p53 accumulation. Exp. Cell Res. 179:565–574.
  • Koeffler, H. P., C. Miller, Μ. A. Nicolson, J. Ranyard, and R. A. Bosselman. 1986. Increased expression of p53 protein in human leukemia and lymphoma. Proc. Natl. Acad. Sci. USA 83:4035–4039.
  • Levine, A. J., J. Momand, and C. A. Finley. 1991. The p53 tumor suppressor gene. Nature (London) 351:453–456.
  • Li, J.-P., A. D. D’Andrea, H. F. Lodish, and D. Baltimore. 1990. Activation of cell growth by binding of Friend spleen focusforming virus gp55 glycoprotein to the erythropoietin receptor. Nature (London) 343:762–764.
  • Longmore, G. D., and H. F. Lodish. 1991. An activating mutation in the murine erythropoietin receptor induces erythroleukemia in mice: a cytokine receptor superfamily oncogene. Cell 67:1089–1102.
  • Lotem, J., E. J. Cragoe, Jr., and L. Sachs. 1991. Rescue from programmed cell death in leukemic and normal myeloid cells. Blood 78:953–960.
  • Lu, X., S. H. Park, T. C. Thompson, and D. P. Lane. 1992. Ras-induced hyperplasia occurs with mutation of p53, but activated ras and myc together can induce carcinoma without p53 mutation. Cell 70:153–161.
  • Marks, P. A., and R. A. Rifkind. 1978. Erythroleukemia differentiation. Annu. Rev. Biochem. 47:419–448.
  • Marshall, C. J. 1991. Tumor suppressor genes. Cell 64:313–326.
  • McClinton, D., J. Stafford, L. Brents, T. P. Bender, and W. Μ. Kuehl. 1990. Differentiation of mouse erythroleukemia cells is blocked by late up-regulation of a c-myb transgene. Mol. Cell. Biol. 10:705–710.
  • Meek, D. W., S. Simon, U. Kikkawa, and W. Eckhart. 1990. The p53 tumor suppressor protein is phosphorylated at serine 38, by casein kinase II. EMBO J. 9:3253–3260.
  • Mercer, W. E., Μ. T. Shields, Μ. Amin, G. I. Saure, E. Appella, J. W. Romano, and S. J. Ullrich. 1990. Negative growth regulation in a glioblastoma tumor cell line that conditionally expresses human wild-type p53. Proc. Natl. Acad. Sci. USA 87:6166–6170.
  • Michalovitz, D., O. Halevy, and Μ. Oren. 1990. Conditional inhibition of transformation and of cell proliferation by a temperature-sensitive mutant of p53. Cell 62:671–680.
  • Morasca, L., and E. Erba. 1986. Flow cytometry, p. 125–148. In R. I. Fresheuy, (ed.), Animal cell culture: a practical approach. IRL Press, Oxford.
  • Moreau-Gachelin, F., A. Tavitian, and P. Tambourin. 1988. Spi-1 is a putative oncogene in virally induced murine erythro-leukemias. Nature (London) 331:277–280.
  • Mowat, M., A. Chang, N. Kimura, A. Bernstein, and S. Benchimol. 1985. Rearrangements of the cellular p53 gene in erythroleukemic cells transformed by Friend virus. Nature (London) 314:633–636.
  • Munroe, D. G., J. Peacock, and S. Benchimol. 1990. Inactivation of the cellular p53 gene is a common feature of Friend erythroleukemia: relation to dominant transforming alleles. Mol. Cell. Biol. 10:3307–3313.
  • Prochownik, E. V., and J. F. Kukowska. 1986. Deregulated expression of c-myc by murine erythroleukemia cells prevents differentiation. Nature (London) 322:848–850.
  • Prokocimer, Μ., Μ. Shaklai, H. Ben-Bassat, D. Wolf, N. Goldfinger, and V. Rotter. 1986. Expression of p53 in human leukemia and lymphoma. Blood 68:113–118.
  • Richon, V. M., D. G. Ramsey, R. A. Rifkind, and P. A. Marks. 1989. Modulation of the c-myb, c-myc and p53 mRNA and protein levels during induced murine erythroleukemia cell differentiation. Oncogene 4:165–173.
  • Rivas, C. I., D. Wisniewski, A. Strife, A. Perez, C. Lambek, S. Bruno, Z. Darzynkiewicz, and B. Clarkson. 1992. Constitutive expression of p53 protein in enriched normal human marrow blast cell populations. Blood 79:1982–1986.
  • Ruscetti, S. K., N. J. Janesch, A. Chakraborti, S. T. Sawyer, and W. D. Hankins. 1990. Friend spleen focus-forming virus induces factor independence in an erythropoietin-dependent erythroleukemia cell line. J. Virol. 64:1057–1062.
  • Smith, L. J., E. A. McCulloch, and S. Benchimol. 1986. Expression of the p53 oncogene in acute myeloblastic leukemia. J. Exp. Med. 164:751–761.
  • Southern, P. J., and P. Berg. 1982. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1:327–341.
  • Sturzbecher, H. W., T. Maimets, P. Chumakov, R. Brain, C. Addison, V. Simanis, K. Rudge, R. Philp, Μ. Grimaldi, W. Court, and J. R. Jenkins. 1990. p53 interacts with p34 cdc2 in mammalian cells: implications for cell cycle control and oncogenesis. Oncogene 5:795–801.
  • Tambourin, P. E., F. Wendling, C. Jasmin, and F. Smadja-Joffe. 1979. The physiopathology of Friend leukemia. Leuk. Res. 3:117–129.
  • Watson, P. A., H. H. Hanauske-Abel, A. Flint, and Μ. Lalande. 1991. Mimosine reversibly arrests cell cycle progression at the Gl-S phase border. Cytometry 12:242–246.
  • Williams, G. T., C. A. Smith, E. Spooncer, T. Μ. Dexter, and D. R. Taylor. 1990. Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis. Nature (London) 343:76–79.
  • Wyllie, A. H., R. G. Morris, A. L. Smith, and D. Dunlop. 1984. Chromatin cleavage in apoptosis: association with condensed chromatin morphology and dependence on macromolecular synthesis. J. Pathol. 142:67–77.
  • Yonish-Roach, E., D. Resnitsky, J. Lotem, L. Sachs, A. Kimchi, and Μ. Oren. 1991. Wild-type p53 induces apoptosis of myeloid leukemic cells that is inhibited by interleukin-6. Nature (London) 352:345–347.

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