Expression of trkA cDNA in Neuroblastomas Mediates Differentiation In Vitro and In Vivo

References

• Adams, J. C., and F. M. Watt. 1989. Fibronectin inhibits the terminal differentiation of human keratinocytes. Nature (London) 340:307–309.
   PubMed Web of Science ®Google Scholar
• Azar, C. G., N. J. Scavarda, C. P. Reynolds, and G. M. Brodeur. 1990. Multiple defects of the nerve growth factor receptor in human neuroblastomas. Cell Growth Differ. 1:421–428.
   PubMedGoogle Scholar
• Birren, S. J., and D. J. Anderson. 1990. A v-myc-immortalized sympathoadrenal progenitor cell line in which neuronal differentiation is initiated by FGF but not NGF. Neuron 4:189–201.
   PubMedGoogle Scholar
• Bothwell, M.%% 1991. Tissue localization of nerve growth factor and nerve growth factor receptors. Curr. Top. Microbiol. Immunol. 165:55–70.
   PubMedGoogle Scholar
• Chao, M. V.%% 1992. Neurotrophin receptors: a window into neuronal differentiation. Neuron 9:583–593.
   PubMed Web of Science ®Google Scholar
• Chirgwin, J. M., A. E. Przybyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299.
   PubMed Web of Science ®Google Scholar
• Cowan, N. J., P. R. Dobner, E. V. Fuchs, and D. W. Cleveland. 1983. Expression of human alpha-tubulin genes: interspecies conservation of 3′ untranslated regions. Mol. Cell. Biol. 3:1738–1745.
   PubMed Web of Science ®Google Scholar
• Curran, T., G. Peters, C. Van Beveren, N. M. Teich, and I. M. Verma. 1982. FBJ murine osteosarcoma virus: identification and molecular cloning of biologically active proviral DNA. J. Virol. 44:674–682.
   PubMed Web of Science ®Google Scholar
• Dammerman, M., S. H. Yen, and B. Shafit Zagardo. 1989. Sequence of a human MAP-2 region sharing epitopes with Alzheimer neurofibrillary tangles. J. Neurosci. Res. 24:487–495.
   PubMedGoogle Scholar
• Eager, K. B.%% 1991. Molecular characterization of human trk proto-oncogene product monoclonal antibodies. Oncogene 6:819–824.
   PubMedGoogle Scholar
• Giard, D. J., S. A. Aaronson, G. J. Todaro, P. Arnstein, J. H. Kersey, H. Dosik, and W. P. Parks. 1973. In vitro cultivation of human tumors: establishment of cell lines derived from a series of solid tumors. J. Natl. Cancer Inst. 51:1417–1423.
   PubMed Web of Science ®Google Scholar
• Grady Leopardi, E. F., M. Schwab, A. R. Ablin, and W. Rosenau. 1986. Detection of N-myc oncogene expression in human neuroblastoma by in situ hybridization and blot analysis: relationship to clinical outcome. Cancer Res. 46:3196–3199.
   PubMedGoogle Scholar
• Greenberg, M. E., L. A. Greene, and E. B. Ziff. 1985. Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells. J. Biol. Chem. 260:14101–14110.
   PubMed Web of Science ®Google Scholar
• Hattori, K., P. Angel, M. M. Le Beau, and M. Karin. 1988. Structure and chromosomal localization of the functional intron-less human JUN protooncogene. Proc. Natl. Acad. Sci. USA 85:9148–9152.
   PubMedGoogle Scholar
• Hempstead, B. L., D. Martin Zanca, D. R. Kaplan, L. F. Parada, and M. V. Chao. 1991. High-affinity NGF binding requires coexpression of the trk proto-oncogene and the low-affinity NGF receptor. Nature (London) 350:678–683.
   PubMed Web of Science ®Google Scholar
• Hempstead, B. L., L. S. Schleifer, and M. V. Chao. 1989. Expression of functional nerve growth factor receptors after gene transfer. Science 243:373–375.
   PubMed Web of Science ®Google Scholar
• Ibanez, C. F., T. Ebendal, G. Barbany, J. Murray Rust, T. L. Blundell, and H. Persson. 1992. Disruption of the low affinity receptor-binding site in NGF allows neuronal survival and differentiation by binding to the trk gene product. Cell 69:329–341.
   PubMed Web of Science ®Google Scholar
• Ignatius, M. J., C. R. Chandler, and E. M. Shooter. 1985. Nerve growth factor-treated, neurite-bearing PC12 cells continue to synthesize DNA. J. Neurosci. 5:343–351.
   PubMedGoogle Scholar
• Ikenaka, K., K. Nakahira, C. Takayama, K. Wada, H. Ha-tanaka, and K. Mikoshiba. 1990. Nerve growth factor rapidly induces expression of the 68-kDa neurofilament gene by post-transcriptional modification in PC12h-R cells. J. Biol. Chem. 265:19782–19785.
   PubMedGoogle Scholar
• Ip, N. Y., T. N. Stitt, P. Tapley, R. Klein, D. J. Glass, J. Fandl, L. A. Greene, M. Barbacid, and G. D. Yancopoulos. 1993. Similarities and differences in the way neurotrophins interact with the Trk receptors in neuronal and nonneuronal cells. Neuron 10:137–149.
   PubMed Web of Science ®Google Scholar
• Ito, E., N. Nomura, and R. Narayanan. 1990. Transcriptional regulation of early growth response genes in FOS-expressing PC-12 cells. Cell Regul. 1:347–357.
   PubMedGoogle Scholar
• Jessell, T. M.%% 1988. Adhesion molecules and the hierarchy of neural development. Neuron 1:3–13.
   PubMed Web of Science ®Google Scholar
• Jing, S., P. Tapley, and M. Barbacid. 1992. Nerve growth factor mediates signal transduction through trk homodimer receptors. Neuron 9:1067–1079.
   PubMed Web of Science ®Google Scholar
• Johnson, D., A. Lanahan, C. R. Buck, A. Sehgal, C. Morgan, E. Mercer, M. Bothwell, and M. Chao. 1986. Expression and structure of the human NGF receptor. Cell 47:545–554.
   PubMed Web of Science ®Google Scholar
• Karns, L. R., S. C. Ng, J. A. Freeman, and M. C. Fishman. 1987. Cloning of complementary DNA for GAP-43, a neuronal growth-related protein. Science 236:597–600.
   PubMedGoogle Scholar
• Kato, K., A. Kanamori, Y. Wakamatsu, S. Sawai, and H. Kondoh. 1991. Tissue distribution of N-myc expression in the early organogenesis period of the mouse embryo. Dev. Growth Differ. 33:29–36.
   Google Scholar
• Klein, R., S. Q. Jing, V. Nanduri, E. O Rourke, and M. Barbacid. 1991. The trk proto-oncogene encodes a receptor for nerve growth factor. Cell 65:189–197.
   PubMed Web of Science ®Google Scholar
• Kuwano, R., H. Usui, T. Maeda, K. Araki, T. Yamakuni, T. Kurihara, and Y. Takahashi. 1987. Tissue distribution of rat S-100 alpha and beta subunit mRNAs. Brain Res. 388:79–82.
   PubMedGoogle Scholar
• Kuwano, R., H. Usui, T. Maeda, T. Fukui, N. Yamanari, E. Ohtsuka, M. Ikehara, and Y. Takahashi. 1984. Molecular cloning and the complete nucleotide sequence of cDNA to mRNA for S-100 protein of rat brain. Nucleic Acids Res. 12:7455–7465.
   PubMedGoogle Scholar
• Lee, K. F., E. Li, L. J. Huber, S. C. Landis, A. H. Sharpe, M. V. Chao, and R. Jaenisch. 1992. Targeted mutation of the gene encoding the low affinity NGF receptor p75 leads to deficits in the peripheral sensory nervous system. Cell 69:737–749.
   PubMed Web of Science ®Google Scholar
• Leonard, D. G., E. B. Ziff, and L. A. Greene. 1987. Identification and characterization of mRNAs regulated by nerve growth factor in PC12 cells. Mol. Cell. Biol. 7:3156–3167.
   PubMed Web of Science ®Google Scholar
• Loeb, D. M., and L. A. Greene. 1993. Transfection with trk restores “slow” NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants. J. Neurosci. 13:2919–2929.
   PubMedGoogle Scholar
• Loeb, D. M., J. Maragos, D. Martin Zanca, M. V. Chao, L. F. Parada, and L. A. Greene. 1991. The trk proto-oncogene rescues NGF responsiveness in mutant NGF-nonresponsive PC12 cell lines. Cell 66:961–966.
   PubMedGoogle Scholar
• MacLeod, A. R. 1981. Expression of the mRNA coding for glyceraldehyde-3-phosphate dehydrogenase. Eur. J. Biochem. 119:353–358.
   PubMedGoogle Scholar
• Marchetti, D., and J. R. Perez Polo. 1987. Nerve growth factor receptors in human neuroblastoma cells. J. Neurochem. 49:475–486.
   PubMedGoogle Scholar
• Martin Zanca, D., R. Oskam, G. Mitra, T. Copeland, and M. Barbacid. 1989. Molecular and biochemical characterization of the human trk proto-oncogene. Mol. Cell. Biol. 9:24–33.
   PubMedGoogle Scholar
• Matsushima, H., and E. Bogenmann. 1990. Nerve growth factor (NGF) induces neuronal differentiation in neuroblastoma cells transfected with the NGF receptor cDNA. Mol. Cell. Biol. 10:5015–5020.
   PubMedGoogle Scholar
• Matsushima, H., and E. Bogenmann. 1992. Modulation of neuroblastoma cell differentiation by the extracellular matrix. Int. J. Cancer 51:727–732.
   PubMedGoogle Scholar
• Matsushima, H., and E. Bogenmann. 1992. Bi-modal differentiation pattern in a new human neuroblastoma cell line in vitro. Int. J. Cancer 51:250–258.
   PubMedGoogle Scholar
• Meakin, S. O., and E. M. Shooter. 1991. Molecular investigations on the high-affinity nerve growth factor receptor. Neuron 6:153–163.
   PubMedGoogle Scholar
• Nakagawara, A., M. Arima Nakagawara, N. J. Scavarda, C. G. Azar, A. B. Cantor, and G. M. Brodeur. 1993. Association between high levels of expression of the TRK gene and favorable outcome in human neuroblastoma. N. Engl. J. Med. 328:847–854.
   PubMed Web of Science ®Google Scholar
• Nomura, N., M. Ide, S. Sasamoto, M. Matsui, T. Date, and R. Ishizaki. 1990. Isolation of human cDNA clones of jun-related genes, jun-B and jun-D. Nucleic Acids Res. 18:3047–3048.
   PubMedGoogle Scholar
• Pleasure, S. J., U. R. Reddy, G. Venkatakrishnan, A. K. Roy, J. Chen, A. H. Ross, J. Q. Trojanowski, D. E. Pleasure, and V. M. Lee. 1990. Introduction of nerve growth factor (NGF) receptors into a medulloblastoma cell line results in expression of high-and low-affinity NGF receptors but not NGF-mediated differentiation. Proc. Natl. Acad. Sci. USA 87:8496–8500.
   PubMedGoogle Scholar
• Radeke, M. J., T. P. Misko, C. Hsu, L. A. Herzenberg, and E. M. Shooter. 1987. Gene transfer and molecular cloning of the rat nerve growth factor receptor. Nature (London) 325:593–597.
   PubMed Web of Science ®Google Scholar
• Rodriguez Tebar, A., G. Dechant, R. Goetz, and Y. A. Barde. 1992. Binding of neurotrophin-3 to its neuronal receptors and interactions with nerve growth factor and brain-derived neuro-trophic factor. EMBO J. 11:917–922.
   PubMedGoogle Scholar
• Ruoslahti, E., and Y. Yamaguchi. 1991. Proteoglycans as modulators of growth factor activities. Cell 64:867–869.
   PubMed Web of Science ®Google Scholar
• Sano, K., H. Nakamura, S. Mabuchi, T. Tanaka, A. Nakagawara, and Y. Takai. 1990. Expression of the smg p25A (a ras p21-like GTP-binding protein) gene in human neuroblastoma cell lines and tumor tissues. Cancer Res. 50:7242–7245.
   PubMedGoogle Scholar
• Schlessinger, J., and A. Ullrich. 1992. Growth factor signaling by receptor tyrosine kinases. Neuron 9:383–391.
   PubMed Web of Science ®Google Scholar
• Schwab, M., K. Alitalo, K. H. Klempnauer, H. E. Varmus, J. M. Bishop, F. Gilbert, G. Brodeur, M. Goldstein, and J. Trent. 1983. Amplified DNA with limited homology to myc cellular oncogene is shared by human neuroblastoma cell lines and a neuroblastoma tumour. Nature (London) 305:245–248.
   PubMed Web of Science ®Google Scholar
• Seeger, R. C., G. M. Brodeur, H. Sather, A. Dalton, S. E. Siegel, K. Y. Wong, and D. Hammond. 1985. Association of multiple copies of the N-myc oncogene with rapid progression of neuroblastomas. N. Engl. J. Med. 313:1111–1116.
   PubMed Web of Science ®Google Scholar
• Seeger, R. C., S. E. Siegel, and N. Sidell. 1982. Neuroblastoma: clinical perspectives, monoclonal antibodies, and retinoic acid. Ann. Intern. Med. 97:873–884.
   PubMed Web of Science ®Google Scholar
• Sheng, M., and M. E. Greenberg. 1990. The regulation and function of c-fos and other immediate early genes in the nervous system. Neuron 4:477–485.
   PubMed Web of Science ®Google Scholar
• Sonnenfeld, K. H., and D. N. Ishii. 1985. Fast and slow nerve growth factor binding sites in human neuroblastoma and rat pheochromocytoma cell lines: relationship of sites to each other and to neurite formation. J. Neurosci. 5:1717–1728.
   PubMedGoogle Scholar
• Stein, R., S. Orit, and D. J. Anderson. 1988. The induction of a neural-specific gene, SCG10, by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable. Dev. Biol. 127:316–325.
   PubMedGoogle Scholar
• Suzuki, T., E. Bogenmann, H. Shimada, D. Stram, and R. C. Seeger. 1993. Lack of high-affinity nerve growth factor receptors in aggressive neuroblastomas. J. Natl. Cancer Inst. 85:377–384.
   PubMedGoogle Scholar
• Tahira, T., Y. Ishizaka, F. Itoh, M. Nakayasu, T. Sugimura, and M. Nagao. 1991. Expression of the ret proto-oncogene in human neuroblastoma cell lines and its increase during neuronal differentiation induced by retinoic acid. Oncogene 6:2333–2338.
   PubMedGoogle Scholar
• Takahashi, K., T. Isobe, Y. Ohtsuki, T. Akagi, H. Sonobe, and T. Okuyama. 1984. Immunohistochemical study on the distribution of alpha and beta subunits of S-100 protein in human neoplasm and normal tissues. Virchows Arch. B 45:385–396.
   Google Scholar
• Tapley, P., F. Lamballe, and M. Barbacid. 1992. K252a is a selective inhibitor of the tyrosine protein kinase activity of the trk family of oncogenes and neurotrophin receptors. Oncogene 7:371–381.
   PubMed Web of Science ®Google Scholar
• Torres, M., F. L. Hall, and K. O. Neill. 1993. Stimulation of human neutrophils with formyl-methionyl-leucyl-phenylala-nine induces tyrosine phosphorylation and activation of two distinct mitogen-activated protein-kinases. J. Immunol. 150: 1563–1577.
   PubMed Web of Science ®Google Scholar
• Weskamp, G., and L. F. Reichardt. 1991. Evidence that biological activity of NGF is mediated through a novel subclass of high affinity receptors. Neuron 6:649–663.
   PubMed Web of Science ®Google Scholar
• Yaeger, M. J., A. Koestner, K. Marushige, and Y. Marushige. 1992. The use of nerve growth factor as a reverse transforming agent for the treatment of neurogenic tumors: in vivo results. Acta Neuropathol. 83:624–629.
   PubMedGoogle Scholar