Genetic Dissection of Centromere Function

REFERENCES

• Apostol, B., and C. L. Greer. 1988. Copy number and stability of yeast 2 μ-based plasmids carrying a transcription-conditional centromere. Gene 67:59–68.
   PubMedGoogle Scholar
• Baker, R. E., M. Fitzgerald-Hayes, and T. C. O’Brien. 1989. Purification of the yeast centromere-binding protein CP1 and a mutational analysis of its binding site. J. Biol. Chem. 264:10843–10850.
   PubMedGoogle Scholar
• Baker, R. E., and D. C. Masison. 1990. Isolation of the gene encoding the Saccharomyces cerevisiae centromere-binding protein CPI. Mol. Cell. Biol. 10:1863–1872.
   PubMedGoogle Scholar
• Bernat, R. L., G. G. Borisy, N. F. Rothfield, and W. C. Earnshaw. 1990. Injection of anticentromere antibodies in interphase disrupts events required for chromosome movement at mitosis. J. Cell Biol. 111:1519–1533.
   PubMed Web of Science ®Google Scholar
• Bernat, R. L., M. R. Delannoy, N. F. Rothfield, and W. C. Earnshaw. 1991. Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis. Cell 66:1229–1238.
   PubMedGoogle Scholar
• Bitoun, R., and A. Zamir. 1986. Spontaneous amplification of yeast CEN ARS plasmids. Mol. Gen. Genet. 204:98–102.
   PubMedGoogle Scholar
• Bloom, K. S., and J. Carbon. 1982. Yeast centromere DNA is in a unique and highly ordered structure in chromosomes and small circular minichromosomes. Cell 29:305–317.
   PubMed Web of Science ®Google Scholar
• Bram, R. J., and R. D. Kornberg. 1987. Isolation of a Saccharomyces cerevisiae centromere DNA binding protein, its human homolog, and its possible role as a transcription factor. Mol. Cell. Biol. 7:403–409.
   PubMedGoogle Scholar
• Brinkley, B. R., M. W. Valdivia, A. Tousson, and R. D. Balczon. 1989. The kinetochore: structure and molecular orientation, p. 77–118. In J. S. Hyams and B. R. Brinkley (ed.), Mitosis molecules and mechanisms. Academic Press Inc., San Diego, Calif.
   Google Scholar
• Cai, M., and R. W. Davis. 1989. Purification of a yeast centromere-binding protein that is able to distinguish single-base-pair mutations in its recognition site. Mol. Cell. Biol. 9:2544–2550.
   PubMedGoogle Scholar
• Cai, M., and R. W. Davis. 1990. Yeast centromere binding protein CBF1, of the helix-loop-helix family, is required for chromosome stability and methionine prototrophy. Cell 61:437446.
   Google Scholar
• Carbon, J., and L. Clarke. 1984. Structural and functional analysis of a yeast centromere (CEN3). J. Cell Sci. Suppl. 1:43–58.
   PubMedGoogle Scholar
• Chlebowicz-Sledziewska, E., and A. Z. Sledziewski. 1985. Construction of multicopy yeast plasmids with regulated centromere function. Gene 39:25–31.
   PubMedGoogle Scholar
• Clarke, L., and J. Carbon. 1985. The structure and function of yeast centromeres. Annu. Rev. Genet. 19:29–56.
   PubMed Web of Science ®Google Scholar
• Erhart, E., and C. P. Hollenberg. 1983. The presence of a defective LEU2 gene on 2μ DNA recombinant plasmids of Saccharomyces cerevisiae is responsible for curing and high copy number. J. Bacteriol. 156:635–635.
   Google Scholar
• Futcher, B., and J. Carbon. 1986. Toxic effects of excess cloned centromeres. Mol. Cell. Biol. 6:2213–2222.
   PubMed Web of Science ®Google Scholar
• Gaudet, A. M., and M. Fitzgerald-Hayes. 1990. The function of centromeres in chromosome segregation, p. 845–881. In P. R. Strauss and S. H. Wilson (ed.), The eukaryotic nucleus, vol. 2. The Telford Press, West Caldwell, N.J.
   Google Scholar
• Hartwell, L. H., and T. A. Weinert. 1989. Checkpoints: controls that ensure the order of cell cycle events. Science 246:629–634.
   PubMed Web of Science ®Google Scholar
• Hegemann, J. H., J. H. Shero, G. Cottarel, P. Philippsen, and P. Hieter. 1988. Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.. Mol. Cell. Biol. 8:2523–2535.
   PubMed Web of Science ®Google Scholar
• Hill, A., and K. Bloom. 1987. Genetic manipulation of centromere function. Mol. Cell. Biol. 7:2397–2405.
   PubMedGoogle Scholar
• Hill, A., and K. Bloom. 1989. The acquisition and processing of dicentric chromosomes in yeast. Mol. Cell. Biol. 9:1368–1370.
   PubMedGoogle Scholar
• Jehn, B., R. Niedenthal, and J. H. Hegemann. 1991. In vivo analysis of Saccharomyces cerevisiae centromere CDE III sequence: requirements for mitotic chromosome segregation. Mol. Cell. Biol. 11:5212–5221.
   PubMedGoogle Scholar
• Kingsbury, J., and D. Koshland. 1992. Centromere dependent binding of yeast minichromosomes to microtubules in vitro. Cell 66:483–495.
   Google Scholar
• Koshland, D., and P. Hieter. 1987. Visual assay for chromosome ploidy. Methods Enzymol. 155:351–372.
   PubMedGoogle Scholar
• Lechner, J., and J. Carbon. 1991. A 240 kD multisubunit protein complex (CBF3) is a major component of the budding yeast centromere. Cell 64:717–725.
   PubMed Web of Science ®Google Scholar
• Mellor, J., W. Jiang, J. Rathjen, C. A. Barnes, T. Hinz, J. H. Hegemann, and P. Philippsen. 1990. CPF1, a yeast protein which functions in centromeres and promoters. EMBO J. 9:4017–4026.
   PubMedGoogle Scholar
• Moens, P. B. 1979. Kinetochore microtubule numbers of different sized chromosomes. J. Cell Biol. 83:556–561.
   PubMed Web of Science ®Google Scholar
• Murphy, M. R., D. M. Fowlkes, and M. Fitzgerald-Hayes. 1991. Analysis of centromere function in Saccharomyces cerevisiae using synthetic centromere mutants. Chromosoma 101:189–197.
   PubMedGoogle Scholar
• Ng, R., and J. Carbon. 1987. Mutational and in vitro proteinbinding studies on centromere DNA from Saccharomyces cerevisiae.. Mol. Cell. Biol. 7:4522–4534.
   PubMedGoogle Scholar
• Runge, K. W., R. J. Wellinger, and V. A. Zakian. 1991. Effects of excess centromeres and excess telomeres on chromosome loss rates. Mol. Cell. Biol. 11:2919–2928.
   PubMedGoogle Scholar
• Runge, K. W., and V. A. Zakian. 1989. Introduction of excess telomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation. Mol. Cell. Biol. 9:1488–1497.
   PubMedGoogle Scholar
• Saunders, M., M. Fitzgerald-Hayes, and K. Bloom. 1988. Chromatin structure of altered yeast centromeres. Proc. Natl. Acad. Sci. USA 85:175–179.
   PubMedGoogle Scholar
• Schulman, I., and K. S. Bloom. 1991. Centromeres: an integrated protein/DNA complex required for chromosome move-ment. Annu. Rev. Cell Biol. 7:311–336.
   PubMedGoogle Scholar
• Schulman, I., and K. S. Bloom. Unpublished data.
   Google Scholar
• Shero, J. H., M. Koval, F. Spencer, R. E. Palmer, P. Hieter, and D. Koshland. 1991. Analysis of chromosome segregation in Saccharomyces cerevisiae, p. 749–773. In C. Guthrie and G. R. Fink (ed.), Guide to yeast genetics and molecular biology. Academic Press Inc., San Diego, Calif.
   Google Scholar
• Simerly, C., R. Balczon, B. R. Brinkley, and G. Schatten. 1990. Microinjected kinetochore antibodies interfere with chromosome movement in meiotic and mitotic mouse oocytes. J. Cell Biol. 111:1491–1504.
   PubMed Web of Science ®Google Scholar
• Smith, D. R., A. P. Smyth, and D. T. Moir. 1990. Amplification of large artificial chromosomes. Proc. Natl. Acad. Sci. USA 87:8242–8426.
   PubMed Web of Science ®Google Scholar
• Spencer, F., and P. Hieter. 1992. Centromere DNA mutations induce a mitotic delay in Saccharomyces cerevisiae.. Proc.Natl. Acad. Sci. USA 89:8909–8912.
   Google Scholar
• Tschumper, G., and J. Carbon. 1983. Copy number control by a yeast centromere. Gene 23:221–232.
   PubMedGoogle Scholar
• Yeh, E. 1985. Ph.D. thesis. University of California, Santa Barbara.
   Google Scholar