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Transcriptional Regulation

Purification of Early-B-Cell Factor and Characterization of its DNA-Binding Specificity

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Pages 3392-3400 | Received 29 Jan 1993, Accepted 25 Mar 1993, Published online: 01 Apr 2023

REFERENCES

  • Adams, B., P. Dorfler, A. Aguzzi, Z. Kozmik, P. Urbanek, I. Maurer-Fogy, and M. Busslinger. 1992. Pax-5 encodes the transcription factor BSAP and is expressed in B lymphocytes, the developing CNS, and adult testis. Genes Dev. 6:1589–1607.
  • Barberis, A., K. Widenhorn, L. Vitelli, and M. Busslinger. 1990. A novel B-cell lineage-specific transcription factor present at early but not late stages of differentiation. Genes Dev. 4:849–859.
  • Blackwell, T. K., and F. W. Alt. 1988. Immunoglobulin genes, p. 1–60. In B. D. Hames and D. M. Glover (ed.), Molecular immunology. IRL Press, Washington, D.C.
  • Blackwell, T. K., and H. Weintraub. 1990. Differences and similarities in DNA-binding preferences of MyoD and E2A protein complexes revealed by binding site selection. Science 250:1104–1110.
  • Cherayil, B. J., and S. Pillai. 1991. The ω/λ5 surrogate immunoglobulin light chain is expressed on the surface of transitional B lymphocytes in murine bone marrow. J. Exp. Med. 173:111–116.
  • Cooper, M. D., and P. D. Burrows. 1989. B-cell differentiation, p. 1–22. In T. Honjo, F. W. Alt, and T. H. Rabbits (ed.), Immunoglobulin genes. Academic Press, London.
  • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Feldhaus, A. L., D. Mbangkollo, K. L. Arvin, C. A. Klug, and H. Singh. 1992. BLyF, a novel cell-type- and stage-specific regulator of the B-lymphocyte gene mb-1.. Mol. Cell. Biol. 12:1126–1133.
  • Ghosh, S., A. M. Gifford, L. R. Riviere, P. Tempst, G. P. Nolan, and D. Baltimore. 1990. Cloning of the p50 DNA binding subunit of NF-κB: homology to rel and dorsal. Cell 62:1019–1029.
  • Glass, C. K., J. M. Holloway, O. V. Devary, and M. G. Rosenfeld. 1988. The thyroid hormone receptor binds with opposite transcriptional effects to a common sequence motif in thyroid hormone and estrogen response elements. Cell 54:313–323.
  • Hager, D. A., and R. R. Burgess. 1980. Elution of protein from sodium dodecyl sulfate-polyacrylamide gels, removal of sodium dodecyl sulfate, and renaturation of enzymatic activity: results with sigma subunit of E. coli RNA polymerase, wheat germ DNA topoisomerase, and other enzymes. Anal. Biochem. 109:76–86.
  • Hagman, J., C. Belanger, A. Travis, C. Turck, and R. Grosschedl. Cloning and functional characterization of early B cell factor, a regulator of lymphocyte-specific gene expression. Genes Dev., in press.
  • Hagman, J., A. Travis, and R. Grosschedl. 1991. A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation. EMBO J. 10:34093417.
  • Hermanson, G. G., M. Briskin, D. Sigman, and R. Wall. 1989. Immunoglobulin enhancer and promoter motifs 5′ of the B29 B-cell-specific gene. Proc. Natl. Acad. Sci. USA 86:7341–7345.
  • Hermanson, G. G., D. Eisenberg, P. W. Kincade, and R. Wall. 1988. B29: a member of the immunoglobulin gene superfamily exclusively expressed on B-lineage cells. Proc. Natl. Acad. Sci. USA 85:6890–6894.
  • Hombach, J., T. Tsubata, L. Leclercq, H. Stappert, and M. Reth. 1990. Molecular components of the B-cell antigen receptor complex of the IgM class. Nature (London) 343:760–762.
  • Jantzen, H.-M., U. Strahle, B. Gloss, F. Stewart, W. Schmid, M. Boshart, R. Miksicek, and G. Schutz. 1987. Cooperativity of glucocorticoid response elements located far upstream of the tyrosine aminotransferase gene. Cell 49:29–38.
  • Kadonaga, J. T., and R. Tjian. 1986. Affinity purification of sequence-specific DNA binding proteins. Proc. Natl. Acad. Sci. USA 83:5889–5893.
  • Kieran, M., V. Blank, F. Logeat, J. Vandekerckhove, F. Lottspeich, O. Le Bail, M. B. Urban, P. Kourilsky, P. A. Baeuerle, and A. Israel. 1990. The DNA binding subunit of NF-κB is identical to factor KBF-1 and homologous to the rel oncogene product. Cell 62:1007–1018.
  • Klock, G., U. Strahle, and G. Schutz. 1987. Oestrogen and glucocorticoid responsive elements are closely related but distinct. Nature (London) 329:734–736.
  • Kozmik, Z., S. Wang, P. Dörfler, B. Adams, and M. Busslinger. 1992. The promoter of the CD19 gene is a target for the B-cell-specific transcription factor BSAP. Mol. Cell. Biol. 12:2662–2672.
  • Kudo, A., and F. Melchers. 1987. A second gene, VpreB in the λ5 locus of the mouse, which appears to be selectively expressed in pre-B lymphocytes. EMBO J. 6:2267–2272.
  • Liebermann, T. A., and D. Baltimore. 1991. Transcriptional regulation of immunoglobulin gene expression. Mol. Aspects Cell. Regul. 6:385–407.
  • Lo, K., N. R. Landau, and S. T. Smale. 1991. LyF-1, a transcriptional regulator that interacts with a novel class of promoters for lymphocyte-specific genes. Mol. Cell. Biol. 11:5229–5243.
  • Martinez, E., F. Givel, and W. Wahli. 1987. The estrogenresponsive element as an inducible enhancer: DNA sequence requirements and conversion to a glucocorticoid-responsive element. EMBO J. 6:3719–3727.
  • Matsuuchi, L., M. R. Gold, A. Travis, R. Grosschedl, A. L. DeFranco, and R. B. Kelly. 1992. The membrane IgM-associated proteins MB-1 and Ig-β are sufficient to promote surface expression of a partially functional B-cell antigen receptor in a nonlymphoid cell line. Proc. Natl. Acad. Sci. USA 89:3404–3408.
  • Muller, M. M., S. Ruppsert, W. Schaffner, and P. Matthias. 1988. A cloned octamer transcription factor stimulates tran-scription from lymphoid-specific promoters in non-B cells. Nature (London) 336:544–551.
  • Nolan, G. P., S. Ghosh, H.-C. Liou, P. Tempst, and D. Baltimore. 1991. DNA binding and IκB inhibition of the cloned p65 subunit of NF-κB, a rel-related polypeptide. Cell 64:961–969.
  • Rolink, A., and F. Melchers. 1991. Molecular and cellular origins of B lymphocyte diversity. Cell 66:1081–1094.
  • Sakaguchi, N., C. N. Berger, and F. Melchers. 1986. Isolation of a cDNA copy of an RNA species expressed in murine pre-B cells. EMBO J. 5:2139–2147.
  • Sakaguchi, N., S.-I. Kashiwamura, M. Kimoto, P. Thalmann, and F. Melchers. 1988. B lymphocyte lineage-restricted expression of mb-1, a gene with CD3-like structural properties. EMBO J. 7:3457–3464.
  • Scheidereit, C., J. A. Cromlish, T. Gerster, K. Kawakami, C. Balmaceda, R. A. Currie, and R. G. Roeder. 1988. A human lymphoid-specific transcription factor that activates immunoglobulin genes is a homeo-box protein. Nature (London) 336:551–557.
  • Sen, R., and D. Baltimore. 1986. Inducibility of κ immunoglobulin enhancer-binding protein NF-κB by a posttranslational mechanism. Cell 47:921–928.
  • Staudt, L. M., R. G. Clerc, H. Singh, J. H. LeBowitz, P. A. Sharp, and D. Baltimore. 1988. Cloning of a lymphoid-specific cDNA encoding a protein binding the regulatory octamer DNA motif. Science 241:577–580.
  • Travis, A., J. Hagman, and R. Grosschedl. 1991. Heterogeneously initiated transcription from the pre-B- and B-cell-specific mb-1 promoter: analysis of the requirement for upstream factor-binding sites and initiation site sequences. Mol. Cell. Biol. 11:5756–5766.
  • Treisman, R. 1987. Identification and purification of a polypeptide that binds to the c-fos serum response element. EMBO J. 6:2711–2717.
  • Tsubata, T., and M. Reth. 1990. The products of pre-B cellspecific genes (λ5 and VpreB) and the immunoglobulin μ chain form a complex that is transported onto the cell surface. J. Exp. Med. 172:973–976.
  • Umesono, K., K. K. Murakami, C. C. Thompson, and R. M. Evans. 1991. Direct repeats as selective response elements for thyroid hormone, retinoic acid, and vitamin D3 receptors. Cell 65:1255–1266.
  • Venkitaraman, A. R., G. T. Williams, M. Dariavach, and M. S. Neuberger. 1991. The B-cell antigen receptor of the five immunoglobulin classes. Nature (London) 352:777–781.

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