E2A and E2-2 are Subunits of B-Cell-Specific E2-Box DNA-Binding Proteins

REFERENCES

• Aronheim, A., H. Ohlsson, C. W. Park, T. Edlund, and M. Walker. 1991. Distribution and characterization of helix-loop- helix enhancer-binding proteins from pancreatic beta-cells and lymphocytes. Nucleic Acids Res. 19:3893–3899.
   PubMedGoogle Scholar
• Bain, G. Unpublished results.
   Google Scholar
• Bain, G., and C. Murre. Unpublished results.
   Google Scholar
• Brennan, T. J., T. Chakruborty, and E. N. Olson. 1991. Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis. Proc. Natl. Acad. Sci. USA 88:5675–5679.
   PubMedGoogle Scholar
• Brennan, T. J., and E. N. Olson. 1990. Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization. Genes Dev. 4:582–595.
   PubMedGoogle Scholar
• Buskin, J. N., and S. D. Hauschka. 1989. Identification of a myocyte nuclear factor which binds to the muscle-specific enhancer of the mouse muscle creatine kinase gene. Mol. Cell. Biol. 9:2627–2640.
   PubMedGoogle Scholar
• Caudy, M., E. H. Grell, C. Dambly-Chaudiere, A. Ghysen, L. Y. Jan, and Y. N. Jan. 1988. The maternal sex determination gene daughterless has zygotic activity necessary for the formation of peripheral neurons in Drosophila. Genes Dev. 2;843–852.
   PubMed Web of Science ®Google Scholar
• Church, G. M., A. Ephrussi, W. Gilbert, and S. Tonegawa. 1985. Cell type specific contacts to immunoglobulin enhancers in nuclei. Nature (London) 313:798–801.
   PubMed Web of Science ®Google Scholar
• Cline, T. W. 1976. A sex-specific, temperature sensitive maternal effect of the daughterless mutation of Drosophila melanogaster, Genetics 84:723–742.
   PubMedGoogle Scholar
• Cordle, S., E. Henderson, H. Masuoka, P. A. Weil, and R. Stein. 1991. Pancreatic β-cell-type-specific transcription of the insulin gene is mediated by basic helix-loop-helix DNA-binding proteins. Mol. Cell. Biol. 11:1734–1738.
   PubMedGoogle Scholar
• Cronmiller, C., and T. W. Cline. 1987. The sex determination gene daughterless has different functions in the germ line versus the soma. Cell 48:479–487.
   PubMed Web of Science ®Google Scholar
• Davis, R. L., P. F. Cheng, A. B. Lassar, and H. Weintraub. 1990. The MyoD DNA binding domain contains a recognition code for muscle-specific gene activation. Cell 60:733–746.
   PubMedGoogle Scholar
• Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
   PubMed Web of Science ®Google Scholar
• Ephrussi, A., G. M. Church, S. Tonegawa, and W. Gilbert. 1985. B-lineage-specific interactions of a immunoglobulin enhancer with cellular factors in vivo. Science 227:134–140.
   PubMed Web of Science ®Google Scholar
• Harlow, E., and D. Lane. 1988. Antibodies: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Henthorn, P., et al. Unpublished results.
   Google Scholar
• Henthorn, P., M. Kiledjian, and T. Kadesch. 1990. Two distinct transcription factors that bind the immunoglobulin enhancer μE5/κE2 motif. Science 247:467–470.
   PubMed Web of Science ®Google Scholar
• Hu, J.-S., E. N. Olson, and R. E. Kingston. 1992. HEB, a helix-loop-helix protein related to E2A and ITF2 that can modulate the DNA-binding ability of myogenic regulatory factors. Mol. Cell. Biol. 12:1031–1042.
   PubMed Web of Science ®Google Scholar
• Jaynes, J. B., J. E. Johnson, J. N. Buskin, C. L. Gartside, and S. D. Hauschka. 1988. The muscle creatine kinase gene is regulated by multiple upstream elements, including a musclespecific enhancer. Mol. Cell. Biol. 8:62–70.
   PubMedGoogle Scholar
• Kamps, M. P., C. Murre, X.-H. Sun, and D. Baltimore. 1990. A new homeobox gene contributes the DNA binding domain of the t(1; 19) translocation protein in pre-B ALL. Cell 60:547–555.
   PubMed Web of Science ®Google Scholar
• Kiledjian, M., L. K. Su, and T. Kadesch. 1988. Identification and characterization of two functional domains within the murine heavy-chain enhancer. Mol. Cell. Biol. 8:145–149.
   PubMedGoogle Scholar
• Lassar, A. B., J. N. Buskin, D. Lockshon, R. L. Davis, S. Apone, S. D. Hauschka, and H. Weintraub. 1989. MyoD is a sequencespecific DNA binding protein requiring a region of myc homology to bind to the muscle creatine kinase enhancer. Cell 58:823–831.
   PubMedGoogle Scholar
• Lassar, A. B., R. L. Davis, W. E. Wright, T. Kadesch, C. Murre, A. Voronova, D. Baltimore, and H. Weintraub. 1991. Functional activity of myogenic HLH proteins requires hetero-oligomerization with E12/E47-like proteins in vivo. Cell 66:305–315.
   PubMed Web of Science ®Google Scholar
• Lenardo, M., J. W. Pierce, and D. Baltimore. 1987. Proteinbinding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 236:1573–1577.
   PubMed Web of Science ®Google Scholar
• Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Moss, L. G., J. B. Moss, and W. J. Rutter. 1988. Systematic binding analysis of the insulin gene transcription control region: insulin and immunoglobulin enhancers utilize similar transactivators. Mol. Cell. Biol. 8:2620–2627.
   PubMedGoogle Scholar
• Murre, C. Unpublished results.
   Google Scholar
• Murre, C., P. S. McCaw, and D. Baltimore. 1989. A new DNA binding and dimerization motif in immunoglobulin enhancer binding, daughterless, MyoD, and myc proteins. Cell 56:777–783.
   PubMed Web of Science ®Google Scholar
• Murre, C., P. S. McCaw, H. Vaessin, M. Caudy, L. Y. Jan, Y. N. Jan, C. V. Cabrera, J. N. Buskin, S. D. Hauschka, A. B. Lassar, H. Weintraub, and D. Baltimore. 1989. Interactions between heterologous helix-loop-helix proteins generate complexes that bind specifically to a common DNA sequence. Cell 58:537–544.
   PubMed Web of Science ®Google Scholar
• Murre, C., A. Voronova, and D. Baltimore. 1991. B-cell- and myocyte-specific E2-box-binding factors contain E12/E47-like subunits. Mol. Cell. Biol. 11:1156–1160.
   PubMedGoogle Scholar
• Nelson, C., L. P. Shen, A. Meister, E. Fodor, and W. J. Rutter. 1990. Pan: a transcriptional regulator that binds chymotrypsin, insulin and AP-4 enhancer motifs. Genes Dev. 4:1035–1044.
   PubMedGoogle Scholar
• Piette, J., J.-L. Bessereau, M. Huchet, and J.-P. Changeux. 1990. Two adjacent MyoDl-binding sites regulate expression of the acetylcholine receptor α-subunit gene. Nature (London) 345:353–355.
   PubMedGoogle Scholar
• Ruezinsky, D., H. Beckmann, and T. Kadesch. 1991. Modulation of the Igh enhancers cell type specificity through a genetic switch. Genes Dev. 5:29–37.
   PubMedGoogle Scholar
• Schüssel, M., A. Voronova, and D. Baltimore. 1991. Helix loop helix transcription factor-E47 activates germ-line immunoglobulin heavy-chain gene transcription and rearrangement in a pre-T-cell line. Genes Dev. 5:1367–1376.
   PubMedGoogle Scholar
• Sun, X.-Y., and D. Baltimore. 1991. An inhibitory domain of E12 transcription factor prevents DNA binding in E12 homodimers but not in E12 heterodimers. Cell 64:459–470.
   PubMed Web of Science ®Google Scholar
• Voronova, A., and D. Baltimore. 1990. Mutations that disrupt DNA binding and dimer formation in the E47 helix-loop-helix protein map to distinct domains. Proc. Natl. Acad. Sci. USA 87:4722–4726.
   PubMed Web of Science ®Google Scholar
• Whelan, J., S. R. Cordle, E. Henderson, P. A. Weil, and R. Stein. 1990. Identification of a pancreatic β-cell insulin gene transcription factor that binds to and appears to activate celltype-specific gene expression: its possible relationship to other cellular factors that bind to a common insulin gene sequence. Mol. Cell. Biol. 10:1564–1572.
   PubMedGoogle Scholar
• Zhuang, Y., C. Kim, S. Bartelmez, P. Cheng, M. Groudine, and H. Weintraub. 1992. Helix-loop-helix transcription factors E12 and E47 are no essential for skeletal or cardiac myogenesis, erythropoiesis, chondrogenesis, or neurogenesis. Proc. Natl. Acad. Sci. USA 89:12132–12136.
   PubMed Web of Science ®Google Scholar