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Cell Growth and Development

Growth Factor, Steroid, and Steroid Antagonist Regulation of Cyclin Gene Expression Associated With Changes in T-47D Human Breast Cancer Cell Cycle Progression

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Pages 3577-3587 | Received 23 Dec 1992, Accepted 16 Mar 1993, Published online: 01 Apr 2023

REFERENCES

  • Alexander, I. E., C. L. Clarke, J. Shine, and R. L. Sutherland. 1989. Progestin inhibition of progesterone receptor gene expression in human breast cancer cells. Mol. Endocrinol. 3:1377–1386.
  • Ali, I. U., G. Merlo, R. Callahan, and R. Lidereau. 1989. The amplification unit on chromosome 11q13 in aggressive primary human breast tumors entails the bcl-1, int-2 and hst loci. Oncogene 4:89–92.
  • Baserga, R. 1990. The cell cycle: myths and realities. Cancer Res. 50:6769–6771.
  • Beato, M. 1989. Gene regulation by steroid hormones. Cell 56:335–344.
  • Buckley, M. F., K. J. E Sweeney, J. A. Hamilton, R. L. Sini, D. L. Manning, R. I. Nicholson, A. deFazio, C. K. W. Watts, E. A. Musgrove, and R. L. Sutherland. Expression and amplification of cyclin genes in human breast cancer. Oncogene, in press.
  • Chan, Y.-L., R. Gutell, H. F. Noller, and I. Wool. 1984. The nucleotide sequence of a rat 18 S ribosomal ribonucleic acid gene and a proposal for the secondary structure of 18 S ribosomal ribonucleic acid. J. Biol. Chem. 259:224–230.
  • Cocks, B. G., G. Viaro, S. E. Bodrug, and J. A. Hamilton. 1992. Suppression of growth factor-induced CYL1 cyclin gene expression by antiproliferative agents. J. Biol. Chem. 267:12307–12310.
  • Dubik, D., T. C. Dembinski, and R. P. C. Shiu. 1987. Stimulation of c-myc oncogene expression associated with estrogen- induced proliferation of human breast cancer cells. Cancer Res. 47:6517–6521.
  • Dulic, V., E. Lees, and S. I. Reed. 1992. Association of human cyclin E with a periodic GrS phase protein kinase. Science 257:1958–1961.
  • Elledge, S. J., R. Richman, F. L. Hall, R. T. Williams, N. Lodgson, and J. W. Harper. 1992. CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle. Proc. Natl. Acad. Sci. USA 89:2907–2911.
  • Elledge, S. J., and M. R. Spottswood. 1991. A new human p34 protein kinase, CDK2, identified by complementation of a cdc28 mutation in Saccharomyces cerevisiae, is a homolog of Xenopus Egl. EMBO J. 10:2653–2659.
  • Fawell, S. E., J. A. Lees, R. White, and M. G. Parker. 1990. Characterization and colocalization of steroid binding and dimerization activities in the mouse estrogen receptor. Cell 60:953–962.
  • Furukawa, Y., H. Piwnica-Worms, T. J. Ernst, Y. Kanakura, and J. D. Griffin. 1990. cdc2 gene expression at the G1 to S transition in human T lymphocytes. Science 250:805–808.
  • Girard, F., U. Strausfeld, A. Fernandez, and N. J. C. Lamb. 1991. Cyclin A is required for the onset of DNA replication in mammalian fibroblasts. Cell 67:1169–1179.
  • Heikkila, R., G. Schwab, E. Wickstrom, S. L. Loke, D. H. Pluznik, R. Watt, and L. M. Neckers. 1987. A c-myc antisense oligodeoxynucleotide inhibits entry into S phase but not progress from G0 to G1 Nature (London) 328:445–449.
  • Holt, J. T., R. L. Redner, and A. W. Neinhuis. 1988. An oligomer complementary to c-myc inhibits proliferation of HL-60 promyelocytic cells and induces differentiation. Mol. Cell. Biol. 8:963–973.
  • Hunter, T., and J. Pines. 1991. Cyclins and cancer. Cell 66:1071–1074.
  • Inaba, T., H. Matsushime, M. Valentine, M. F. Roussel, C. J. Sherr, and A. T. Look. 1992. Genomic organization, chromo-somal localization, and independent expression of human cyclin D genes. Genomics 13:565–574.
  • Keydar, I., L. Chen, S. Karby, F. R. Weiss, J. Delarea, M. Radu, S. Chaitcik, and H. J. Brenner. 1979. Establishment and characterization of a cell line of human breast carcinoma origin. Eur. J. Cancer 15:659–670.
  • Koff, A., F. Cross, A. Fisher, J. Schumacher, K. Leguellec, M. Philippe, and J. M. Roberts. 1991. Human cyclin E, a new cyclin that interacts with two members of the CDC2 gene family. Cell 66:1217–1228.
  • Koff, A., A. Giordano, D. Desai, K. Yamashita, J. W. Harper, S. Elledge, T. Nishimoto, D. O. Morgan, B. R. Franza, and J. M. Roberts. 1992. Formation and activation of a cyclin E-cdk2 complex during the G1 phase of the human cell cycle. Science 257:1689–1694.
  • Koga, M., E. A. Musgrove, and R. L. Sutherland. 1989. Modulation of the growth-inhibitory effects of progestins and the antiestrogen hydroxyclomiphene on human breast cancer cells by epidermal growth factor and insulin. Cancer Res. 49:112–116.
  • Koga, M., and R. L. Sutherland. 1987. Epidermal growth factor partially reverses the inhibitory effects of antiestrogens on T 47D human breast cancer cell growth. Biochem. Biophys. Res. Commun. 146:739–745.
  • Lee, M. G., C. J. Norbury, N. K. Spurr, and P. Nurse. 1988. Regulated expression and phosphorylation of a possible mam-malian cell-cycle control protein. Nature (London) 333:676–679.
  • Lee, M. G., and P. Nurse. 1987. Complementation used to clone a human homologue of the fission yeast cell cycle control gene cdc2. Nature (London) 327:31–35.
  • Leung, B. S., and A. H. Potter. 1987. Mode of estrogen action on cell proliferation in CAMA-1 cells: II. Sensitivity of G1 phase population. J. Cell. Biochem. 34:213–225.
  • Lew, D. J., V. Dulie, and S. I. Reed. 1991. Isolation of three novel human cyclins by rescue of G1 cyclin (Cln) function in yeast. Cell 66:1197–1206.
  • Lippman, M., G. Bolan, and K. Huff. 1976. The effects of estrogens and antiestrogens on hormone-responsive human breast cancer in long term tissue culture. Cancer Res. 36:4595–4601.
  • Lippman, M. E., and G. Bolan. 1975. Oestrogen-responsive human breast cancer in long term tissue culture. Nature (London) 256:592–593.
  • Lu, X. P., K. S. Koch, D. J. Lew, V. Dulic, J. Pines, S. I. Reed, T. Hunter, and H. L. Leffert. 1992. Induction of cyclin mRNA and cyclin-associated histone Hl kinase during liver regeneration. J. Biol. Chem. 267:2841–2844.
  • Matsushime, H., M. E. Ewen, D. K. Strom, J.-Y. Kato, S. K. Hanks, M. F. Roussel, and C. J. Sherr. 1992. Identification and properties of an atypical catalytic subunit (p34PSK-J3/cdk4) for mammalian D type G1 cyclins. Cell 71:323–334.
  • Matsushime, H., M. F. Roussel, R. A. Ashmun, and C. J. Sherr. 1991. Colony-stimulating factor 1 regulates novel cyclins during the G1 phase of the cell cycle. Cell 65:701–713.
  • McGowan, C. H., P. Russell, and S. I. Reed. 1990. Periodic biosynthesis of the human M-phase promoting factor catalytic subunit p34 during the cell cycle. Mol. Cell. Biol. 10:3847–3851.
  • Meyerson, M., G. H. Enders, C.-L. Wu, L.-K. Su, C. Gorka, C. Nelson, E. Harlow, and L.-H. Tsai. 1992. A family of cdc2-related kinases. EMBO J. 11:2909–2917.
  • Motokura, T., T. Bloom, H. G. Kim, H. Jüppner, J. Ruderman, H. Kronenberg, and A. Arnold. 1991. A novel cyclin encoded by a bcl1-linked candidate oncogene. Nature (London) 350:512–515.
  • Motokura, T., K. Keyomarsi, H. M. Kronenberg, and A. Arnold. 1992. Cloning and characterization of human cyclin D3, a cDNA closely related in sequence to the PRADl/cyclin D1 protooncogene. J. Biol. Chem. 267:20412–20415.
  • Murray, A. M., and M. W. Kirschner. 1989. Dominoes and clocks: the union of two views of the cell cycle. Science 246:614–621.
  • Murray, A. W., M. J. Solomon, and M. W. Kirschner. 1989. The role of cyclin synthesis and degradation in the control of maturation promoting factor activity. Nature (London) 339:280–286.
  • Musgrove, E. A., C. S. L Lee, and R. L. Sutherland. 1991. Progestins both stimulate and inhibit breast cancer cell cycle progression while increasing expression of transforming growth factor α, epidermal growth factor receptor, c-fos, and c-myc genes. Mol. Cell. Biol. 11:5032–5043.
  • Musgrove, E. A., and R. L. Sutherland. 1991. Steroids, growth factors and cell cycle controls in breast cancer, p. 305–331. In M. E. Lippman and R. B. Dickson (ed.), Regulatory mechanisms in breast cancer. Kluwer Academic Publishers, Boston.
  • Musgrove, E. A., and R. L. Sutherland. Acute effects of growth factors on T-47D breast cancer cell cycle progression. Submitted for publication.
  • Musgrove, E. A., and R. L. Sutherland. Effects of the progestin antagonist RU 486 on T-47D cell proliferation. Submitted for publication.
  • Musgrove, E. A., A. E. Wakeling, and R. L. Sutherland. 1989. Points of action of estrogen antagonists and a calmodulin antagonist within the MCF-7 human breast cancer cell cycle. Cancer Res. 49:2398–2404.
  • Ninomiya-Tsuji, J., S. Nomoto, H. Yasuda, S. I. Reed, and K. Matsumoto. 1991. Cloning of a human cDNA encoding a CDC2- related kinase by complementation of a budding yeast cdc28 mutation. Proc. Natl. Acad. Sci. USA 88:9006–9010.
  • Nurse, P. 1990. Universal control mechanism regulating onset of M-phase. Nature (London) 344:503–508.
  • Pagano, M., R. Pepperkok, F. Verde, W. Ansorge, and G. Draetta. 1992. Cyclin A is required at two points in the human cell cycle. EMBO J. 11:961–971.
  • Pauli, U., S. Chrysogelos, J. Stein, G. Stein, and H. Nick. 1987. Protein DNA interactions in vivo upstream of a cell cycle regulated human HA histone gene. Science 236:1308–1311.
  • Pines, J. 1991. Cyclins: wheels within wheels. Cell Growth Differ. 2:305–310.
  • Pines, J., and T. Hunter. 1989. Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2. Cell 58:833–846.
  • Pines, J., and T. Hunter. 1990. Human cyclin A is adenovirus E1A-associated protein p60 and behaves differently from cyclin B. Nature (London) 346:760–763.
  • Raibowol, K., G. Draetta, L. Brizuela, D. Vandre, and D. Beach. 1989. The cdc2 kinase is a nuclear protein that is essential for mitosis in mammalian cells. Cell 57:393–401.
  • Reddel, R. R., L. C. Murphy, and R. L. Sutherland. 1984. Factors affecting the sensitivity of T-47D human breast cancer cells to tamoxifen. Cancer Res. 44:2398–2405.
  • Reed, S. I. 1991. Gl-specific cyclins: in search of an S-phase-promoting factor. Trends Genet. 7:95–99.
  • Santos, G. F., G. K. Scott, W. M. F Lee, E. Liu, and C. Benz. 1988. Estrogen-induced post-transcriptional modulation of c-myc proto-oncogene expression in human breast cancer cells. J. Biol. Chem. 263:9565–9568.
  • Sarup, J. C., K. V. Rao, and C. F. Fox. 1988. Decreased progesterone binding and attenuated progesterone action in cultured human breast carcinoma cells treated with epidermal growth factor. Cancer Res. 48:5071–5078.
  • Shibuya, H., M. Yoneyama, J. Ninomiya-Tsuji, K. Matsumoto, and T. Taniguchi. 1992. IL-2 and EGF receptors stimulate the hematopoietic cell cycle via different signalling pathways: demonstration of a novel role for c-myc. Cell 70:557–567.
  • Stein, G. S., M. A. Plumb, J. L. Stein, F. F. Marashi, L. F. Sierra, and L. L. Baumbach. 1984. Expression of histone genes during the cell cycle in human cells, p. 106–143. In G. S. Stein and J. L. Stein (ed.), Recombinant DNA and cell proliferation. Academic Press, Inc., Orlando, Fla.
  • Sutherland, R. L., R. E. Hall, G. Y. N Pang, E. A. Musgrove, and C. L. Clarke. 1988. Effect of medroxyprogesterone acetate on proliferation and cell cycle kinetics of human mammary carcinoma cells. Cancer Res. 48:5084–5091.
  • Sutherland, R. L., R. E. Hall, and I. W. Taylor. 1983. Cell proliferation kinetics of MCF-7 human mammary carcinoma cells in culture and effects of tamoxifen on exponentially growing and plateau-phase cells. Cancer Res. 43:3998–4006.
  • Taylor, I. W., P. J. Hodson, M. D. Green, and R. L. Sutherland. 1983. Effects of tamoxifen on cell cycle progression of synchronous MCF-7 human mammary carcinoma cells. Cancer Res. 43:4007–4010.
  • Theillet, C., J. Adnane, P. Szepetowski, M.-P. Simon, P. Jeanteur, D. Birnbaum, and P. Gaudray. 1990. BCL-1 participates in the 11q13 amplification found in breast cancer. Oncogene 5:147–149.
  • Tsai, L.-H., E. Harlow, and M. Meyerson. 1991. Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase. Nature (London) 353:174–177.
  • Vignon, F., M. M. Bouton, and H. Rochefort. 1987. Antiestrogens inhibit the mitogenic effect of growth factors on breast cancer cells in the total absence of estrogens. Biochem. Biophys. Res. Commun. 146:1502–1508.
  • Wakeling, A. E. 1991. Steroidal pure antiestrogens, p. 239–257. In M. E. Lippman and R. B. Dickson (ed.), Regulatory mechanisms in breast cancer. Kluwer Academic Press, Boston.
  • Wakeling, A. E., and J. Bowler. 1987. Steroidal pure antioestrogens. J. Endocrinol. 112:R7–R10.
  • Watson, P. H., R. T. Pon, and R. P. C. Shiu. 1991. Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer. Cancer Res. 51:3996–4000.
  • Webster, N. J. G., S. Green, J. R. Jin, and P. Chambon. 1988. The hormone-binding domains of the estrogen and glucocorticoid receptors contain an inducible transcription activation function. Cell 54:199–207.
  • Withers, D. A., R. C. Harvey, J. B. Faust, O. Melnyk, K. Carey, and T. C. Meeker. 1991. Characterization of a candidate bcl-1 gene. Mol. Cell. Biol. 11:4846–4853.
  • Won, K.-A., Y. Xiong, D. Beach, and M. Z. Gilman. 1992. Growth regulated expression of D-type cyclin genes in human diploid fibroblasts. Proc. Natl. Acad. Sci. USA 89:9910–9914.
  • Wong, M. S. J., and L. C. Murphy. 1991. Differential regulation of c-myc by progestins and antiestrogens in T-47D human breast cancer cells. J. Steroid Biochem. Mol. Biol. 39:39–44.
  • Xiong, Y., T. Connolly, B. Futcher, and D. Beach. 1991. Human D-type cyclin. Cell 65:691–699.
  • Xiong, Y., J. Menninger, D. Beach, and D. C. Ward. 1992. Molecular cloning and chromosomal mapping of CCND genes encoding human D-type cyclins. Genomics 13:575–584.

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