1
Views
1
CrossRef citations to date
0
Altmetric
Cell Growth and Development

A GC-Rich Domain With Bifunctional Effects on mRNA and Protein Levels: Implications for Control of Transforming Growth Factor β1 Expression

&
Pages 3588-3597 | Received 31 Jul 1992, Accepted 30 Mar 1993, Published online: 01 Apr 2023

REFERENCES

  • Assoian, R. K., B. E. Fleurdelys, H. C. Stevenson, P. J. Miller, D. K. Madtes, E. W. Raines, R. Ross, and M. B. Sporn. 1987. Expression and secretion of type β transforming growth factor by activated human macrophages. Proc. Natl. Acad. Sci. USA 84:6020–6024.
  • Ausubel, F. M., R. Brent, R. E. Kinston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl. 1987. Current protocols in molecular biology. John Wiley & Sons, Inc., New York.
  • Battegay, E. J., E. W. Raines, R. A. Seifert, D. F. Bowen-Pope, and R. Ross. 1990. TGF-β induces bimodial proliferation of connective tissue cells via complex control of an autocrine PDGF loop. Cell 63:515–524.
  • Braun, R. E., J. J. Peschon, R. R. Behringer, R. L. Brinster, and R. D. Palmiter. 1989. Protamine 3′-untranslated sequences regulate temporal translation control and subcellular localization of growth hormone in spermatids of transgenic mice. Genes Dev. 3:793–802.
  • Brawerman, G. 1989. Determinants of messenger RNA stability. Cell 57:9–10.
  • Cathala, G., J. F. Savouret, B. Mendez, B. L. West, M. Karin, J. Martial, and J. Baxter. 1983. Laboratory methods: a method for isolation of intact translationally active ribonucleic acid. DNA (New York) 2:329–335.
  • Caughman, S. W., M. W. Hentze, T. A. Rouault, J. B. Harford, and R. D. Klausner. 1988. The iron-responsive element is the single element responsible for iron-dependent translational regulation of ferritin biosynthesis. J. Biol. Chem. 263:19048–19052.
  • de Martin, R., B. Haendler, R. Hofer-Warbinek, H. Gaugitsch, M. Wrann, H. Schlusener, J. M. Seifert, S. Bodmer, A. Fontana, and E. Hofer. 1987. Complementary DNA for human glioblastoma-derived T cell suppressor factor, a novel member of the transforming growth factor-β gene family. EMBO J. 6:3673–3677.
  • DeNoto, F. M., D. D. Moore, and H. M. Goodman. 1981. Human growth hormone DNA sequence and mRNA structure: possible alternative splicing. Nucleic Acids Res. 9:3719–3730.
  • Derynck, R., J. A. Jarrett, E. Y. Chen, D. H. Eaton, J. R. Bell, R. K. Assoian, A. B. Roberts, M. B. Sporn, and D. V. Goeddel. 1985. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature (London) 316:701–705.
  • Derynck, R., J. A. Jarrett, E. Y. Chen, and D. V. Goeddel. 1986. The murine transforming growth factor-β precursor. J. Biol. Chem. 261:4377–4379.
  • Derynck, R., P. B. Lindquist, A. Lee, D. Wen, J. Tamm, J. L. Graycar, L. Rhee, A. J. Mason, D. A. Miller, R. J. Coffey, H. L. Moses, and E. Y. Chen. 1988. A new type of transforming growth factor-β, TGF-β3. EMBO J. 7:3737–3743.
  • Fu, L., Ye, R., L. W. Browder, and R. N. Johnston. 1991. Translational potentiation of messenger RNA with secondary structure in Xenopus. Science 251:807–810.
  • Geiser, A. G., S.-J. Kim, A. B. Roberts, and M. B. Sporn. 1991. Characterization of the mouse transforming growth factor β1 promoter and activation by the Ha-ras oncogene. Mol. Cell. Biol. 11:84–92.
  • Gorman, C. 1985. High efficiency gene transfer into mammalian cells, p. 143–190. In D. M. Glover (ed.), DNA cloning, vol. 2. IRL Press, Ltd., Oxford.
  • Grens, A., and I. E. Scheffler. 1990. The 5′- and 3′-untranslated regions of ornithine decarboxylase mRNA affect the translational efficiency. J. Biol. Chem. 265:11810–11816.
  • Hanks, S. K., R. Armour, J. H. Baldwin, F. Maldonado, J. Spiess, and R. W. Holley. 1988. Amino acid sequence of the BSC-1 cell growth inhibitor (polyergin) deduced from the nucleotide sequence of the cDNA. Proc. Natl. Acad. Sci. USA 85:79–83.
  • Jackson, R. J., and N. Standart. 1990. Do the poly(A) tail and 3′ untranslated region control mRNA translation? Cell 62:15–24.
  • Jakowlew, S. B., P. J. Dillard, P. Kondaiah, M. B. Sporn, and A. B. Roberts. 1988. Complementary deoxyribonucleic acid cloning of a novel transforming growth factor-β messenger ribonucleic acid from chick embryo chondrocytes. Mol. Endocrinol. 2:747–755.
  • Jakowlew, S. B., P. J. Dillard, M. B. Sporn, and A. B. Roberts. 1988. Nucleotide sequence of chicken transforming growth factor-β1 (TGF-β1). Nucleic Acids Res. 16:8730.
  • Jakowlew, S. B., P. J. Dillard, M. B. Sporn, and A. B. Roberts. 1988. Complementary deoxyribonucleic acid cloning of an mRNA encoding transforming growth factor-beta 4 from chicken embryo chondrocytes. Mol. Endocrinol. 2:1186–1195.
  • Kageyama, R., and I. Pastan. 1989. Molecular cloning and characterization of a human DNA binding factor that represses transcription. Cell 59:815–825.
  • Kim, S.-J., F. Denhez, K. Y. Kim, J. T. Holt, M. B. Sporn, and A. B. Roberts. 1989. Activation of the second promoter of the transforming growth factor-βl gene by transforming growth factor-βl and phorbol ester occurs through the same target sequence. J. Biol. Chem. 264:19373–19378.
  • Kim, S.-J., A. Glick, M. B. Sporn, and A. B. Roberts. 1989. Characterization of the promoter region of the human trans-forming growth factor-βl gene. J. Biol. Chem. 264:402–408.
  • Kondaiah, P., M. J. Sands, J. M. Smith, A. Fields, A. B. Roberts, M. B. Sporn, and D. A. Melton. 1990. Identification of a novel transforming growth factor-β (TGF-β5) mRNA in Xenopus laevis. J. Biol. Chem. 265:1089–1093.
  • Kondaiah, P., E. Van Obberghen-Schilling, R. L. Ludwig, R. Dhar, M. B. Sporn, and A. B. Roberts. 1988. cDNA cloning of porcine transforming growth factor-βl mRNAs. J. Biol. Chem. 263:18313–18317.
  • Kozak, M. 1989. The scanning model for translation: an update. J. Cell Biol. 108:229–241.
  • Kozak, M. 1989. Circumstances and mechanisms of inhibition of translation by secondary structure in eucaryotic mRNAs. Mol. Cell. Biol. 9:5134–5142.
  • Kruys, V., M. Wathelet, P. Poupart, R. Contreras, W. Fiers, J. Content, and G. Huez. 1987. The 3′ untranslated region of the human interferon-β mRNA has an inhibitory effect on translation. Proc. Natl. Acad. Sci. USA 84:6030–6034.
  • Lafyatis, R., R. Lechleider, S.-J. Kim, S. Jakowlew, A. B. Roberts, and M. B. Sporn. 1990. Structural and functional characterization of the transforming growth factor-β3 promoter. J. Biol. Chem. 265:19128–19136.
  • Madisen, L., N. R. Webb, T. M. Rose, H. Marquardt, T. Ikeda, D. Twardzik, S. Seyedin, and A. F. Purchio. 1988. Transforming growth factor-β2: cDNA cloning and sequence analysis. DNA 7:1–8.
  • Manzella, J. M., and P. J. Blackshear. 1990. Regulation of rat ornithine decarboxylase mRNA translation by its 5′-untrans-lated region. J. Biol. Chem. 265:11817–11822.
  • Massagué, J. 1990. The transforming growth factor-β family. Annu. Rev. Cell Biol. 6:597–641.
  • Miller, D. A., A. Lee, R. W. Pelton, E. Y. Chen, H. L. Moses, and R. Derynck. 1989. Murine transforming growth factor-β2 cDNA sequence and expression in adult tissues and embryos. Mol. Endocrinol. 3:1108–1114.
  • Moses, H. L., E. Y. Yang, and J. A. Pietenpol. 1990. TGF-β stimulation and inhibition of cell proliferation: new mechanistic insights. Cell 63:245–247.
  • Pelletier, J., and N. Sonenberg. 1985. Insertion mutagenesis to increase secondary structure within the 5′ noncoding region of a eucaryotic mRNA reduces translational efficiency. Cell 40:515–526.
  • Postlethwaite, A. E., J. Keski-Oja, H. L. Moses, and A. H. Kang. 1987. Stimulation of the chemotactic migration of human fibroblasts by transforming growth factor beta. J. Exp. Med. 165:251–256.
  • Qian, S. W., P. Kondaiah, W. Casscells, A. B. Roberts, and M. B. Sporn. 1991. A second messenger RNA species of transforming growth factor β1 in infarcted rat heart. Cell Regul. 2:241–249.
  • Rao, C. D., M. Pech, K. C. Robbins, and S. A. Aaronson. 1988. The 5′ untranslated sequence of the c-sis/platelet-derived growth factor 2 transcript is a potent translational inhibitor. Mol. Cell. Biol. 8:284–292.
  • Rouault, T. A., M. W. Hentze, S. W., Caughman, J. B. Harford, and R. D. Klausner. 1988. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science 241:1207–1210.
  • Rouault, T. A., M. W. Hentze, D. J. Haile, J. B. Harford, and R. D. Klausner. 1989. The iron-responsive element binding protein: a method for the affinity purification of a regulatory RNA-binding protein. Proc. Natl. Acad. Sci. USA 86:5768–5772.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Scotto, L., P. I. Vaduva, R. E. Wager, and R. K. Assoian. 1990. Type βl transforming growth factor gene expression: a cor-rected mRNA structure reveals a downstream phorbol ester responsive element in human cells. J. Biol. Chem. 265:2203–2208.
  • Sharpies, K., G. D. Plowman, T. M. Rose, D. R. Twardzik, and A. F. Purchio. 1987. Cloning and sequence analysis of simian transforming growth factor-β cDNA. DNA 6:239–244.
  • Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′ untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659–667.
  • Sporn, M. B., and A. B. Roberts. 1990. TGF-β: problems and prospects. Cell Regul. 1:875–882.
  • Ten Dijke, P., P. Hansen, K. K. Iwata, C. Pieler, and J. G. Foulkes. 1988. Identification of another member of the trans-forming growth factor type β gene family. Proc. Natl. Acad. Sci. USA 85:4715–4719.
  • Theil, E. C. 1990. Regulation of ferritin and transferrin receptor mRNA. J. Biol. Chem. 265:4771–4774.
  • Van Obberghen-Schilling, E., P. Kondaiah, R. L. Ludwig, M. B. Sporn, and C. C. Baker. 1987. Complementary deoxyribonucleic acid cloning of bovine transforming growth factor-βl. Mol. Endocrinol. 1:693–698.
  • Wager, R. E., and R. K. Assoian. 1990. A phorbol ester- regulated ribonuclease system controlling transforming growth factor βl gene expression in hematopoietic cells. Mol. Cell. Biol. 10:5983–5990.
  • Wahl, S. M., D. A. Hunt, L. M. Wakefield, N. McCartney- Francis, L. M. Wahl, A. B. Roberts, and M. B. Sporn. 1987. Transforming growth factor type β induces monocyte chemotaxis and growth factor production. Proc. Natl. Acad. Sci. USA 84:5788–5792.
  • Wakefield, L. M., D. M. Smith, T. Matsui, C. C. Harris, and M. B. Sporn. 1987. Distribution and modulation of the cellular receptor for transforming growth factor-β. J. Cell Biol. 105:965–975.
  • Watrin, F., L. Scotto, R. K. Assoian, and D. J. Wolgemuth. 1991. Cell lineage specificity of expression of the murine transforming growth factor β3 and transforming growth factor β1 genes. Cell Growth Differ. 2:77–83.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.