Differential Transcriptional Activation by v-Myb and c-Myb in Animal Cells and Saccharomyces cerevisiae

REFERENCES

• Berger, S. L., B. Pina, N. Silverman, G. A. Marcus, J. Agapite, J. L. Regier, S. J. Triezenberg, and L. Guarente. 1992. Genetic isolation of ADA2: a potential transcriptional adaptor required for function of certain acidic activation domains. Cell 70:251–265.
   PubMed Web of Science ®Google Scholar
• Biedenkapp, H., U. Borgmeyer, A. E. Sippel, and K.-H. Klempnauer. 1988. Viral myb oncogene encodes a sequence-specific DNA binding activity. Nature (London) 335:835–837.
   PubMed Web of Science ®Google Scholar
• Bortner, D. M., and M. C. Ostrowski. 1991. Analysis of the v-myb structural components important for transactivation of gene expression. Nucleic Acids Res. 19:1533–1539.
   PubMedGoogle Scholar
• Boyle, W. J., J. S. Lipsick, and M. A. Baluda. 1986. Antibodies to the evolutionarily conserved aminoterminal region of the v-myb-encoded protein detect the c-myb protein in widely divergent metazoan species. Proc. Natl. Acad. Sci. USA 83:4685–4689.
   PubMedGoogle Scholar
• Buratowski, S., S. Hahn, P. A. Sharp, and L. Guarente. 1988. Function of a yeast TATA element-binding protein in a mam-malian transcription system. Nature (London) 334:37–42.
   PubMedGoogle Scholar
• Cavallini, B., J. Huet, J. L. Plassat, A. Sentenac, J.-M. Egly, and P. Chambon. 1988. A yeast activity can substitute for the HeLa TATA box factor. Nature (London) 334:77–80.
   PubMedGoogle Scholar
• Chen, C. H., and H. Okayama. 1987. High-efficiency transfor-mation of mammalian cells by plasmid DNA. Mol. Cell. Biol. 7:2745–2752.
   PubMed Web of Science ®Google Scholar
• Chen, J. H. 1980. Expression of endogenous avian myeloblas-tosis virus information in different chicken cells. J. Virol. 36:162–170.
   PubMedGoogle Scholar
• Chien, C. T., P. L. Bartel, R. Sternglanz, and S. Fields. 1991. The two-hybrid system: a method to identify and clone genes for proteins that interact with a protein of interest. Proc. Natl. Acad. Sci. USA 88:9578–9582.
   PubMed Web of Science ®Google Scholar
• Clarke, M. F., J. F. Kukowska-Latallo, E. H. Westin, M. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemia cell differentiation. Mol. Cell. Biol. 8:884–892.
   PubMed Web of Science ®Google Scholar
• Coll, J., S. Saule, P. Martin, M. B. Raes, C. Lagrou, T. Graf, H. Beug, I. E. Simon, and D. Stehelin. 1983. The cellular oncogenes c-myc, c-myb and c-erb are transcribed in defined types of avian hematopoietic cells. Exp. Cell Res. 149:151–162.
   PubMed Web of Science ®Google Scholar
• Dalton, S., and R. Treisman. 1992. Characterization of SAP-1, a protein recruited by serum response factor to the c-fos serum response element. Cell 68:597–612.
   PubMed Web of Science ®Google Scholar
• Dini, P., and J. Lipsick. Submitted for publication.
   Google Scholar
• Donahue, T. F., and A. M. Cigan. 1990. Sequence and structural requirements for efficient translation in yeast. Methods Enzymol. 185:366–372.
   PubMedGoogle Scholar
• Dubendorff, J. W., L. Whittaker, J. Eltman, and J. S. Lipsick. 1992. Carboxy-terminal elements of c-Myb negatively regulate transcriptional activation in cis and in trans. Genes Dev. 6:2524–2535.
   PubMed Web of Science ®Google Scholar
• Eltman, J., and J. Lipsick. Unpublished results.
   Google Scholar
• Evan, G. I., G. K. Lewis, and J. M. Bishop. 1984. Isolation of monoclonal antibodies specific for the products of the avian oncogene myb. Mol. Cell. Biol. 4:2843–2850.
   PubMedGoogle Scholar
• Fields, S., and O. Song. 1989. A novel genetic system to detect protein-protein interactions. Nature (London) 340:245–246.
   PubMed Web of Science ®Google Scholar
• Frampton, J., T. J. Gibson, S. A. Ness, G. Doderlein, and T. Graf. 1991. Proposed structure for the DNA-binding domain of the Myb oncoprotein based on model building and mutational analysis. Protein Eng. 4:891–901.
   PubMedGoogle Scholar
• Gabrielson, O. S., A. Sentenac, and P. Fromageot. 1991. Specific DNA binding by c-Myb: evidence for a double helix-turn-helix-related motif. Science 253:1140–1143.
   PubMedGoogle Scholar
• Garcia, A., K. LaMontagne, D. Reavis, U. Stober-Grasser, and J. S. Lipsick. 1991. Determinants of sequence-specific DNA-binding by p48v-myb. Oncogene 6:265–273.
   PubMedGoogle Scholar
• Gewirtz, A. M., and B. Calabretta. 1988. A c-myb antisense oligodeoxynucleotide inhibits normal human hematopoiesis in vitro. Science 242:1303–1306.
   PubMed Web of Science ®Google Scholar
• Gietz, R. D., and A. Sugino. 1988. New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites. Gene 74:527–534.
   PubMed Web of Science ®Google Scholar
• Gonda, T. J., D. K. Sheiness, and J. M. Bishop. 1982. Tran-scripts from the cellular homologs of retroviral oncogenes: distribution among chicken tissues. Mol. Cell. Biol. 2:617–624.
   PubMed Web of Science ®Google Scholar
• Graf, T. 1992. Myb: a transcriptional activator linking prolifer-ation and differentiation in hematopoietic cells. Curr. Opin. Gen. Dev. 2:249–255.
   PubMedGoogle Scholar
• Grosser, F. A., T. Graf, and J. S. Lipsick. 1991. Protein truncation is required for the activation of the c-myb proto-oncogene. Mol. Cell. Biol. 11:3987–3996.
   PubMedGoogle Scholar
• Grosser, F. A., K. LaMontagne, L. Whittaker, S. Stohr, and J. S. Lipsick. 1992. A highly conserved cysteine in the v-Myb DNA-binding domain is essential for transformation and transcriptional trans-activation. Oncogene 7:1005–1009.
   PubMedGoogle Scholar
• Guehmann, S., G. Vorbrueggen, F. Kalkbrenner, and K. Moelling. 1992. Reduction of a conserved Cys is essential for Myb DNA-binding. Nucleic Acids Res. 20:2279–2286.
   PubMedGoogle Scholar
• Guthrie, C., and G. R. Fink. 1991. Guide to yeast genetics and molecular biology. Academic Press, San Diego, Calif.
   Google Scholar
• Howe, K. M., C. F. L. Reakes, and R. J. Watson. 1990. Characterization of the sequence-specific interaction of mouse c-myb protein with DNA. EMBO J. 9:161–169.
   PubMed Web of Science ®Google Scholar
• Hu, Y. L., R. G. Ramsay, C. Kanei-Ishii, S. Ishii, and T. J. Gonda. 1991. Transformation by carboxyl-deleted Myb reflects increased transactivating capacity and disruption of a negative regulatory domain. Oncogene 6:1549–1553.
   PubMedGoogle Scholar
• Ibanez, C. E., and J. S. Lipsick. 1988. Structural and functional domains of the myb oncogene: requirements for nuclear transport, myeloid transformation, and colony formation. J. Virol. 62:1981–1988.
   PubMedGoogle Scholar
• Ibanez, C. E., and J. S. Lipsick. 1990. trans activation of gene expression by v-myb. Mol. Cell. Biol. 10:2285–2293.
   PubMed Web of Science ®Google Scholar
• Introna, M., J. Golay, J. Frampton, T. Nakano, S. A. Ness, and T. Graf. 1990. Mutations in v-myb alter the differentiation of myelomonocytic cells transformed by the oncogene. Cell 63:1289–1297.
   PubMed Web of Science ®Google Scholar
• Ito, H., Y. Fukuda, K. Murata, and A. Kimura. 1983. Transformation of intact yeast cells treated with alkali cations. J. Bacteriol. 153:163–168.
   PubMed Web of Science ®Google Scholar
• Johnson, A. D., and I. Herskowitz. 1985. A repressor (MAT alpha2 product) and its operator control expression of a set of cell-type-specific genes in yeast. Cell 42:237–247.
   PubMed Web of Science ®Google Scholar
• Johnston, M., and R. W. Davis. 1984. Sequences that regulate the divergent GAL1-GAL10 promoter in Saccharomyces cerevisiae. Mol. Cell. Biol. 4:1440–1448.
   PubMed Web of Science ®Google Scholar
• Kalkbrenner, F., S. Guehmann, and K. Moelling. 1990. Tran-scriptional activation by human c-myb and v-myb genes. Oncogene 5:657–661.
   PubMedGoogle Scholar
• Katzen, A. L., T. B. Romberg, and J. M. Bishop. 1985. Isolation of the proto-oncogene c-myb from Drosophila melanogaster. Cell 41:449–456.
   PubMedGoogle Scholar
• Klempnauer, K.-H., H. Arnold, and H. Biedenkapp. 1989. Activation of transcription by v-myb: evidence for two different mechanisms. Genes Dev. 3:1582–1589.
   PubMedGoogle Scholar
• Klempnauer, K.-H., and A. E. Sippel. 1987. The highly con-served amino-terminal region of the protein encoded by the v-myb oncogene functions as a DNA-binding domain. EMBO J. 6:2719–2725.
   PubMed Web of Science ®Google Scholar
• Lane, T. N., C. E. Ibanez, A. Garcia, T. Graf, and J. S. Lipsick. 1990. Transformation by w-myb correlates with transactivation of gene expression. Mol. Cell. Biol. 10:2591–2598.
   PubMedGoogle Scholar
• Leprince, D., A. Gegonne, J. Coll, C. de Taisne, A. Schnee-berger, C. Lagrou, and D. Stehelin. 1983. A putative second cell-derived oncogene of the avian leukaemia retrovirus E26. Nature (London) 306:395–397.
   PubMed Web of Science ®Google Scholar
• Lillie, J. W., and M. R. Green. 1989. Transcription activation by the adenovirus Ela protein. Nature (London) 338:39–44.
   PubMedGoogle Scholar
• Luscher, B., E. Christenson, D. W. Litchfield, E. G. Krebs, and R. N. Eisenman. 1990. Myb DNA binding inhibited by phos-phorylation at a site deleted during oncogenic activation. Nature (London) 344:517–522.
   PubMedGoogle Scholar
• Luscher, B., and R. N. Eisenman. 1990. New light on Myc and Myb. Part II. Myb. Genes Dev. 4:2235–2241.
   PubMed Web of Science ®Google Scholar
• Ma, J., and M. Ptashne. 1987. A new class of yeast transcrip-tional activators. Cell 51:113–119.
   PubMed Web of Science ®Google Scholar
• Metzger, D., H. H. White, and P. Chambon. 1988. The human estrogen receptor functions in yeast. Nature (London) 334:31–36.
   PubMed Web of Science ®Google Scholar
• Miller, J. H. 1972. Experiments in molecular genetics. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
   Google Scholar
• MoeUing, K., E. Pfaff, H. Beug, P. Beimling, T. Bunte, H. E. Schaller, and T. Graf. 1985. DNA-binding activity is associated with purified myb proteins from AMV and E26 viruses and is temperature-sensitive for E26 ts mutants. Cell 40:983–990.
   PubMedGoogle Scholar
• Mucenski, M. L., K. McLain, A. B. Kier, S. H. Swerdlow, C. M. Schreiner, T. A. Miller, D. W. Pietryga, W. J. Scott, Jr., and S. S. Potter. 1991. A functional c-myb gene is required for normal murine fetal hepatic hematopoiesis. Cell 65:677–689.
   PubMed Web of Science ®Google Scholar
• Ness, S. A., A. Markneu, and T. Graf. 1989. The w-myb oncogene product binds to and activates the promyelocyte-specific mim-1 gene. Cell 59:1115–1125.
   PubMed Web of Science ®Google Scholar
• Nishina, Y., H. Nakagoshi, F. Imamoto, T. J. Gonda, and S. Ishii. 1989. Trans-actrvation by the c-myb proto-oncogene. Nucleic Acids Res. 17:107–117.
   PubMedGoogle Scholar
• Nomura, N., M. Takahashi, M. Matsui, S. Ishii, T. Date, S. Sasamoto, and R. Ishizaki. 1988. Isolation of human cDNA clones of myft-related genes, A-myb and B-myb. Nucleic Acids Res. 16:11075–11089.
   PubMed Web of Science ®Google Scholar
• Nunn, M. F., P. H. Seeburg, C. Moscovici, and P. H. Duesberg. 1983. Tripartite structure of the avian erythroblastosis virus E26 transforming gene. Nature (London) 306:391–395.
   PubMed Web of Science ®Google Scholar
• Ogata, K., H. Hojo, S. Aimoto, T. Nakai, H. Nakamura, A. Sarai, S. Ishii, and Y. Nishimura. 1992. Solution structure of a DNA-binding unit of Myb: a helix-turn-helix-related motif with conserved tryptophans forming a hydrophobic core. Proc. Natl. Acad. Sci. USA 89:6428–6432.
   PubMed Web of Science ®Google Scholar
• Paz-Ares, J., D. Ghosal, U. Wienand, P. A. Peterson, and H. Saedler. 1987. The regulatory cl locus of Zea mays encodes a protein with homology to myb proto-oncogene products and with structural similarities to transcriptional activators. EMBO J. 6:3553–3558.
   PubMed Web of Science ®Google Scholar
• Privalsky, M. L., M. Sharif, and K. R. Yamamoto. 1990. The viral erbA oncogene protein, a constitutive repressor in animal cells, is a hormone-regulated activator in yeast. Cell 63:1277–1286.
   PubMedGoogle Scholar
• Ptashne, M. 1988. How eukaryotic transcriptional activators work. Nature (London) 335:683–689.
   PubMed Web of Science ®Google Scholar
• Punyammalee, B., M. Crabeel, C. de Lannoy, B. Perbal, and N. Glansdorff. 1991. Two c-myb proteins differing by their amino-termini exhibit different transcriptional transactivation activities (yeast/reporter-effector system). Oncogene 6:11–19.
   PubMedGoogle Scholar
• Roussel, M., S. Saule, C. Lagrou, C. Rommens, H. Beug, T. Graf, and D. Stehelin. 1979. Three new types of viral oncogene of cellular origin specific for hematopoietic cell transformation. Nature (London) 281:452–455.
   PubMed Web of Science ®Google Scholar
• Sakura, H., C. Kanei-Ishii, T. Nagase, H. Nakagoshi, T. J. Gonda, and S. Ishii. 1989. Delineation of three functional domains of the transcriptional activator encoded by the c-myb protooncogene. Proc. Natl. Acad. Sci. USA 86:5758–5762.
   PubMed Web of Science ®Google Scholar
• Schena, M., L. P. Freedman, and K. R. Yamamoto. 1989. Mutations in the glucocorticoid receptor zinc finger region that distinguish interdigitated DNA binding and transcriptional en-hancement activities. Genes Dev. 3:1590–1601.
   PubMed Web of Science ®Google Scholar
• Schena, M., and K. R. Yamamoto. 1988. Mammalian glucocor-ticoid receptor derivatives enhance transcription in yeast. Sci-ence 241:965–967.
   PubMedGoogle Scholar
• Schiestl, R. H., and R. D. Geitz. 1989. High efficiency transfor-mation of intact yeast cells using single stranded nucleic acids as carrier. Curr. Genet. 16:339–346.
   PubMed Web of Science ®Google Scholar
• Seed, B., and J.-Y. Sheen. 1988. A simple phase-extraction assay for chloramphenicol acyltransferase activity. Gene 67:271–277.
   PubMed Web of Science ®Google Scholar
• Shen-Ong, G. L. C. 1990. The myb oncogene. Biochim. Biophys. Acta 1032:39–52.
   PubMedGoogle Scholar
• Stober-Grasser, U., B. Brydolf, X. Bin, F. A. Grasser, R. A. Firtel, and J. S. Lipsick. 1992. The Myb DNA-binding domain is highly conserved in Dictyostelium discoideum. Oncogene 7:589–596.
   PubMed Web of Science ®Google Scholar
• Thomas, B., and R. Rothstein. 1989. Elevated recombination rates in transcriptionally active DNA. Cell 56:619–630.
   PubMed Web of Science ®Google Scholar
• Tice-Baldwin, K., G. R. Fink, and K. T. Arndt. 1989. BAS1 has a myb motif and activates HIS4 transcription only in combination with BAS2. Science 246:931–935.
   PubMedGoogle Scholar
• Todokoro, K., R. J. Watson, H. Higo, H. Amanuma, S. Kuramo-chi, H. Yanagisawa, and Y. Ikawa. 1988. Down-regulation of c-myb gene expression is a prerequisite for erythropoietin-induced erythroid differentiation. Proc. Natl. Acad. Sci. USA 85:8900–8904.
   PubMed Web of Science ®Google Scholar
• Westin, E. H., R. C. Gallo, S. K. Arya, A. Eva, L. M. Souza, M. A. Baluda, S. A. Aaronson, and F. Wong-Staal. 1982. Differential expression of the amv gene in human hematopoietic cells. Proc. Natl. Acad. Sci. USA 79:2194–2198.
   PubMed Web of Science ®Google Scholar
• Weston, K. M., and J. M. Bishop. 1989. Transcriptional activa-tion by the v-myb oncogene and its cellular progenitor, c-myb. Cell 58:85–93.
   PubMed Web of Science ®Google Scholar