1
Views
4
CrossRef citations to date
0
Altmetric
DNA Dynamics and Chromosome Structure

A Mitochondrial Retroplasmid Integrates into Mitochondrial DNA by a Novel Mechanism Involving the Synthesis of a Hybrid cDNA and Homologous Recombination

, , &
Pages 6419-6432 | Received 27 Apr 1994, Accepted 07 Jul 1994, Published online: 30 Mar 2023

REFERENCES

  • Ahlquist, P. 1992. Bromovirus RNA replication and transcription. Curr. Opin. Genet. Dev. 2:71–76.
  • Akins, R. A., D. M. Grant, L. L. Stohl, D. A. Bottorff, F. E. Nargang, and A. M. Lambowitz. 1988. Nucleotide sequence of the Varkud mitochondrial plasmid of Neurospora and synthesis of a hybrid transcript with a 5′ leader derived from mitochondrial RNA. J. Mol. Biol. 204:1–25.
  • Akins, R. A., R. L. Kelley, and A. M. Lambowitz. 1986. Mitochondrial plasmids of Neurospora: integration into mitochondrial DNA and evidence for reverse transcription in mitochondria. Cell 47:505–516.
  • Akins, R. A., R. L. Kelley, and A. M. Lambowitz. 1989. Characterization of mutant mitochondrial plasmids of Neurospora spp. that have incorporated tRNAs by reverse transcription. Mol. Cell. Biol. 9:678–691.
  • Akins, R. A., and A. M. Lambowitz. Unpublished data.
  • Bertrand, H. Personal communication.
  • Boer, P. H., and M. W. Gray. 1988. Genes encoding a subunit of respiratory NADH dehydrogenase (ND1) and a reverse transcriptase-like protein (RTL) are linked to ribosomal RNA gene pieces in Chlamydomonas reinhardtii mitochondrial DNA. EMBO J. 7:3501–3508.
  • Clark, J. M. 1988. Novel non-templated nucleotide addition reactions catalyzed by procaryotic and eucaryotic DNA polymerases. Nucleic Acids Res. 16:9677–9686.
  • Collins, R. A., L. L. Stohl, M. D. Cole, and A. M. Lambowitz. 1981. Characterization of a novel plasmid DNA found in mitochondria of N. crassa. Cell 24:443–452.
  • Cummings, D. J., J. M. Domenico, J. Nelson, and M. L. Sogin. 1989. DNA sequence, structure, and phylogenetic relationship of the small subunit rRNA coding region of mitochondrial DNA from Podospora anserina. J. Mol. Evol. 28:232–241.
  • Davis, R. H., and F. J. de Serres. 1970. Genetic and microbiological research techniques for Neurospora crassa. Methods Enzymol. 17A:79–143.
  • Derr, L. K., and J. N. Strathern. 1993. A role for reverse transcripts in gene conversion. Nature (London) 361:170–173.
  • Derr, L. K., J. N. Strathern, and D. J. Garfinkel. 1991. RNA-mediated recombination in S. cerevisiae. Cell 67:355–364.
  • Eickbush, T. H. 1994. Origin and evolutionary relationships of retroelements, p. 121–157. In S. S. Morse (ed.), Evolutionary biology of viruses. Raven Press, New York.
  • Gorbalenya, A. E., E. V. Koonin, A. P. Donchenko, and V. M. Blinov. 1988. A novel superfamily of nucleoside triphosphatebinding motif containing proteins which are probably involved in duplex unwinding in DNA and RNA replication and recombination. FEBS Lett. 235:16–24.
  • Gutell, R. R., B. Weiser, C. R. Woese, and H. F. Noller. 1985. Comparative anatomy of 16-S-like ribosomal RNA. Prog. Nucleic Acid Res. Mol. Biol. 32:155–216.
  • Heckman, J. E., and U. L. RajBhandary. 1979. Organization of tRNA and rRNA genes in N. crassa mitochondria: intervening sequence in the large rRNA gene and strand distribution of the RNA genes. Cell 17:583–595.
  • Heckman, J. E., J. Sarnoff, B. Alzner-DeWeerd, S. Yin, and U. L. RajBhandary. 1980. Novel features in the genetic code and codon reading patterns in Neurospora crassa mitochondria based on sequences of six mitochondrial tRNAs. Proc. Natl. Acad. Sci. USA 77:3159–3163.
  • Kennell, J. C., J. V. Moran, P. S. Perlman, R. A. Butow, and A. M. Lambowitz. 1993. Reverse transcriptase activity associated with maturase-encoding group II introns in yeast mitochondria. Cell 73:133–146.
  • Kennell, J. C., H. Wang, and A. M. Lambowitz. 1994. The Mauriceville plasmid of Neurospora spp. uses novel mechanisms for initiating reverse transcription in vivo. Mol. Cell. Biol. 14:3094–3107.
  • Kroner, P. A., B. M. Young, and P. Ahlquist. 1990. Analysis of the role of brome mosaic virus la-protein domains in RNA replication, using linker insertion mutagenesis. J. Virol. 64:6110–6120.
  • Kubelik, A. R., J. C. Kennell, R. A. Akins, and A. M. Lambowitz. 1990. Identification of Neurospora mitochondrial promoters and analysis of synthesis of the mitochondrial small rRNA in wild-type and the promoter mutant [poky]. J. Biol. Chem. 265:4515–4526.
  • Kuiper, M. T. R., and A. M. Lambowitz. 1988. A novel reverse transcriptase activity associated with mitochondrial plasmids of Neurospora. Cell 55:693–704.
  • Kuiper, M. T. R., J. R. Sabourin, and A. M. Lambowitz. 1990. Identification of the reverse transcriptase encoded by the Mauriceville and Varkud mitochondrial plasmids of Neurospora. J. Biol. Chem. 265:6936–6943.
  • Lambowitz, A. M., R. J. LaPolla, and R. A. Collins. 1979. Mitochondrial ribosome assembly in Neurospora. Two-dimensional gel electrophoretic analysis of mitochondrial ribosomal proteins. J. Cell Biol. 82:17–31.
  • McClure, M. A. 1991. Evolution of retroposons by acquisition or deletion of retrovirus-like genes. Mol. Biol. Evol. 8:835–856.
  • Michel, F., and B. F. Lang. 1985. Mitochondrial class II introns encode proteins related to the reverse transcriptases of retroviruses. Nature (London) 316:641–643.
  • Miller, W. A., J. J. Bujarski, T. W. Dreher, and T. C. Hall. 1986. Minus-strand initiation by brome mosaic virus replicase within the 3′ tRNA-like structure of native and modified RNA templates. J. Mol. Biol. 187:537–546.
  • Mohr, S., and A. M. Lambowitz. Unpublished data.
  • Moran, J. V., S. Zimmerly, R. Eskes, J. C. Kennell, A. M. Lambowitz, R. A. Butow, and P. S. Perlman. Unpublished data.
  • Nargang, F. E., J. B. Bell, L. L. Stohl, and A. M. Lambowitz. 1984. The DNA sequence and genetic organization of a Neurospora mitochondrial plasmid suggest a relationship to introns and mobile elements. Cell 38:441–453.
  • Neefs, J.-M., Y. Van de Peer, P. De Rijk, S. Chapelle, and R. De Wachter. 1993. Compilation of small ribosomal subunit RNA structures. Nucleic Acids Res. 21:3025–3049.
  • Sambrook, J., E. F. Fritsch, and T. Maniatis. 1989. Molecular cloning: a laboratory manual, 2nd ed. Cold Spring Harbor Laboratory Press, Cold Spring Harbor, N.Y.
  • Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467.
  • Wang, H. 1994. Reverse transcription of the Mauriceville mitochondrial plasmid of Neurospora. Ph.D. thesis. The Ohio State University, Columbus, Ohio.
  • Wang, H., J. C. Kennell, M. T. R. Kuiper, J. R. Sabourin, R. Saldanha, and A. M. Lambowitz. 1992. Ilie Mauriceville plasmid of Neurospora crassa: characterization of a novel reverse transcriptase that begins cDNA synthesis at the 3′ end of template RNA. Mol. Cell. Biol. 12:5131–5144.
  • Wang, H., and A. M. Lambowitz. 1993. Reverse transcription of the Mauriceville plasmid of Neurospora. Lack of ribonuclease H activity associated with the reverse transcriptase and possible use of mitochondrial ribonuclease H. J. Biol. Chem. 268:18951–18959.
  • Wang, H., and A. M. Lambowitz. 1993. The Mauriceville plasmid reverse transcriptase can initiate cDNA synthesis de novo and may be related to reverse transcriptase and DNA polymerase progenitor. Cell 75:1071–1081.
  • Xiong, Y., and T. H. Eickbush. 1990. Origin and evolution of retroelements based upon their reverse transcriptase sequences. EMBO J. 9:3353–3362.
  • Zuker, M. 1989. On finding all suboptimal foldings of an RNA molecule. Science 244:48–52.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.