Integration of a Vector Containing a Repetitive LINE-1 Element in the Human Genome

REFERENCES

• Adair, G. M., R. S. Nairn, J. H. Wilson, M. M. Seidman, K. A. Brotherman, C. MacKinnon, and J. B. Scheerer. 1989. Targeted homologous recombination at the adenine phosphoribosyltransferase locus in Chinese hamster cells. Proc. Natl. Acad. Sci. USA 86:4574–4578.
   PubMedGoogle Scholar
• Aratani, Y., R. Okasaki, and H. Koyama. 1992. End extension repair of introduced targeting vectors mediated by homologous recombination in mammalian cells. Nucleic Acids Res. 20:4795–4801.
   PubMedGoogle Scholar
• Arnheim, N. 1983. Concerted evolution of multigene families, p. 38–61. In M. Nei, and R. K. Kolhn (ed.), Evolution of genes and proteins. Sinauer, Sunderland, Mass.
   Google Scholar
• Ausubel, F. M., R. Brent, R. E. Kingston, D. D. Moore, J. G. Seidman, J. A. Smith, and K. Struhl (ed.). 1993. Current protocols in molecular biology. Greene Publishing Associates and Wiley Interscience, New York.
   Google Scholar
• Belmaaza, A., and P. Chartrand. 1994. One-sided invasion events in homologous recombination at double-strand breaks. Mutat. Res. 314:199–208.
   PubMedGoogle Scholar
• Belmaaza, A., E. Milot, J.-F. Villemure, and P. Chartrand. Submitted for publication.
   Google Scholar
• Belmaaza, A., J. C. Wallenburg, S. Brouillette, N. Gusew, and P. Chartrand. 1990. Genetic exchange between endogenous and exogenous LINE-1 repetitive elements in mouse cells. Nucleic Acids Res. 18:6385–6391.
   PubMedGoogle Scholar
• Berinstein, N., N. Pennell, C. A. Ottaway, and M. J. Shulman. 1992. Gene replacement with one-sided homologous recombination. Mol. Cell. Biol. 12:360–367.
   PubMedGoogle Scholar
• Chu, G., H. Hyakawa, and P. Berg. 1987. Electroporation for the efficient transfection of mammalian cells DNA. Nucleic Acids Res. 15:1311–1327.
   PubMed Web of Science ®Google Scholar
• Colbere-Garapin, F., F. Horodniceanu, P. Kourilsky, and A. C. Garapin. 1979. Cloning of the herpes simplex virus type 1 thymidine kinase gene in E. coli K12: selective marker for gene transfer into animal cells. Dev. Biol. Stand. 46:75–82.
   Google Scholar
• Deng, C., and M. R. Capecchi. 1992. Reexamination of gene targeting frequency as a function of the extent of homology between the targeting vector and the target locus. Mol. Cell. Biol. 12:3365–3371.
   PubMed Web of Science ®Google Scholar
• Dover, G. 1982. Molecular drive: a cohesive mode of species evolution. Nature (London) 299:11–117.
   Google Scholar
• Ellis, J., and A. Bernstein. 1989. Gene targeting with retroviral vectors: recombination by gene conversion into regions of nonhomology. Mol. Cell. Biol. 9:1621–1627.
   PubMedGoogle Scholar
• Grimaldi, G., J. Skowronsky, and M. F. Singer. 1984. Defining the beginning and end of KpnI family elements. EMBO J. 3:1753–1759.
   PubMed Web of Science ®Google Scholar
• Higashi, Y., A. Tanae, Y. Inoue, and Y. Fuju-Kuriyama. 1988. Evidence for frequent gene conversions in the steroid 21-hydroxylase (P-450c21) gene: implications for steroid 21-hydroxylase deficiency. Am. J. Hum. Genet. 42:17–25.
   PubMed Web of Science ®Google Scholar
• Hu, X., P. N. Ray, and R. G. Worton. 1991. Mechanisms of tandem duplication in the Duchenne muscular dystrophy gene include both homologous and nonhomologous intrachromosomal recombination. EMBO J. 10:2471–2477.
   PubMedGoogle Scholar
• Hutchison, C. A., III, S. C. Hardies, D. D. Loeb, W. R. Shehee, and M. H. Edgell. 1989. LINEs and related retroposons: long interspersed repeated sequences in the eukaryotic genome, p. 593–617. In D. E. Berg, and M. M. Howe (ed.), Mobile DNA. American Society for Microbiology, Washington, D.C.
   Google Scholar
• Hwu, H. R., J. W. Roberts, E. H. Davidson, and R. J. Britten. 1986. Insertion and/or deletion of many repeated DNA sequences in human and higher ape evolution. Proc. Natl. Acad. Sci. USA 83:3875–3879.
   PubMedGoogle Scholar
• Jurka, J. 1989. Subfamily structure and the evolution of the human L1 family of repetitive sequences. J. Mol. Evol. 29:496–503.
   PubMedGoogle Scholar
• Knight, K. L. 1992. Restricted VH gene usage and gene ratio of antibody diversity in rabbit. Annu. Rev. Immunol. 10:593–616.
   PubMedGoogle Scholar
• Lehrman, M. A., J. L. Goldstein, D. W. Russell, and M. S. Brown. 1987. Duplication of seven exons in LDL receptor gene caused by Alu-Alu recombination in a subject with familial hypercholesterolemia. Cell 48:827–835.
   PubMedGoogle Scholar
• Metzenberg, A. B., G. Wurzer, T. H. J. Huisman, and O. Smithies. 1991. Homology requirements for unequal crossing over in humans. Genetics 128:143–161.
   PubMedGoogle Scholar
• Miller, C. C. J., J. C. McPheat, and W. J. Potts. 1992. Targeted integration of the Ren-1D locus in mouse embryonic stem cells. Proc. Natl. Acad. Sci. USA 89:5020–5024.
   PubMedGoogle Scholar
• Roeder, G. S. 1990. Chromosome synapsis and genetic recombination: their roles in meiotic chromosome segregation. Trends Genet. 6:385–389.
   PubMedGoogle Scholar
• Rouyer, F., M.-C. Simmler, D. C. Page, and J. Weissenbach. 1987. A sex chromosome rearrangement in a human XX male caused by Alu-Alu recombination. Cell 51:417–425.
   PubMed Web of Science ®Google Scholar
• Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467.
   PubMed Web of Science ®Google Scholar
• Scott, A. F., B. J. Schmeckpeper, M. Abdelrazik, C. Theisen Comey, B. O'Hara, J. Pratt Rossiter, T. Cooley, P. Heath, K. D. Smith, and L. Margolet. 1987. Origin of the human L1 elements: proposed progenitor genes deduced from consensus sequence. Genomics 1:113–125.
   PubMedGoogle Scholar
• Skowronski, J., T. G. Fanning, and M. F. Singer. 1988. Unit-length Line-1 transcripts in human teratocarcinoma cells. Mol. Cell. Biol. 8:1385–1397.
   PubMedGoogle Scholar
• Southern, P. J., and P. Berg. 1982. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1:327–341.
   PubMedGoogle Scholar
• Szostak, J. W., W. T. Orr, R. J. Rothstein, and F. W. Stahl. 1983. The double-strand-break repair model for recombination. Cell 33:25–35.
   PubMed Web of Science ®Google Scholar
• te Riele, H., R. E. Maandag, and A. Berns. 1992. Highly efficient gene targeting in embryonic stem cells through homologous recombination with isogenic DNA constructs. Proc. Natl. Acad. Sci. USA 89:5128–5132.
   PubMed Web of Science ®Google Scholar
• Thomas, K. R., and M. R. Capecchi. 1987. Site-directed mutagenesis by gene targeting in mouse embryo-derived stem cells. Cell 51:503–512.
   PubMed Web of Science ®Google Scholar
• Thomas, K. R., K. R. Folger, and M. R. Capecchi. 1986. High frequency targeting of genes to specific sites in the mammalian genome. Cell 44:419–428.
   PubMed Web of Science ®Google Scholar
• Wheeler, C. J., D. Maloney, S. Fogel, and R. S. Goodenow. 1990. Microconversion between murine H-2 genes integrated into yeast. Nature (London) 347:192–194.
   PubMedGoogle Scholar
• Yenofsky, R. L., M. Fine, and J. Fellow. 1990. A mutant neomycin phosphotransferase II gene reduces the resistance of transformants to antibiotic selection pressure. Proc. Natl. Acad. Sci. USA 87:3435–3439.
   PubMed Web of Science ®Google Scholar
• Zheng, H., and J. H. Wilson. 1990. Gene targeting in normal and amplified cell lines. Nature (London) 344:170–173.
   PubMedGoogle Scholar