Eukaryotic Transcription Termination Factor La Mediates Transcript Release and Facilitates Reinitiation by RNA Polymerase III

REFERENCES

• Adeniyi-Jones, S., and M. Zasloff. 1985. Transcription, processing and nuclear transport of a B1 Alu RNA species complementary to an intron of the murine α-fetoprotein gene. Nature (London) 317:81–84.
   PubMedGoogle Scholar
• Arias, J. A., and W. S. Dynan. 1989. Promoter-dependent transcription by RNA polymerase II using immobilized enzyme complexes. J. Biol. Chem. 264:3223–3229.
   PubMedGoogle Scholar
• Bachmann, M., K. Pfeifer, H.-C. Schroder, and W. E. G. Müller. 1990. Characterization of the autoantigen La as a nucleic aciddependent ATPase/dATPase with melting properties. Cell 60:8593.
   Google Scholar
• Bieker, J. J., P. L. Martin, and R. G. Roeder. 1985. Formation of a rate-limiting intermediate in 5S RNA gene transcription. Cell 40:119–127.
   PubMed Web of Science ®Google Scholar
• Bogenhagen, D. F., and D. D. Brown. 1981. Nucleotide sequences in Xenopus 5S DNA required for transcription termination. Cell 24:261–270.
   PubMed Web of Science ®Google Scholar
• Bogenhagen, D. F., W. M. Wormington, and D. D. Brown. 1982. Stable transcription complexes of Xenopus 5S RNA genes: a means to maintain the differentiated state. Cell 28:413–421.
   PubMed Web of Science ®Google Scholar
• Brow, D. A. 1987. In vitro transcripts of a yeast variant 5 S rRNA gene exhibit alterations in 3′-end processing and protein binding. J. Biol. Chem. 262:13959–13965.
   PubMedGoogle Scholar
• Campbell, F. E., and D. R. Setzer. 1992. Transcription termination by RNA polymerase III: uncoupling of polymerase release from termination signal recognition. Mol. Cell. Biol. 12:2260–2272.
   PubMedGoogle Scholar
• Chambers, J. C., and J. D. Keene. 1985. Isolation and analysis of cDNA clones expressing human lupus La antigen. Proc. Natl. Acad. Sci. USA 82:2115–2119.
   PubMed Web of Science ®Google Scholar
• Chambers, J. C., D. Kenan, B. J. Martin, and J. D. Keene. 1988. Genomic structure and amino acid sequence domains of the human La autoantigen. J. Biol. Chem. 263:18043–18051.
   PubMed Web of Science ®Google Scholar
• Chan, E. K., K. F. Sullivan, R. I. Fox, and E. M. Tan. 1989. Sjogren's syndrome nuclear antigen B (La): cDNA cloning, structural domains, and autoepitopes. J. Autoimmun. 2:321–327.
   PubMedGoogle Scholar
• Chang, D.-Y., and R. J. Maraia. 1993. A cellular protein binds Bl and Alu small cytoplasmic RNAs in vitro. J. Biol. Chem. 268:6423–6428.
   PubMedGoogle Scholar
• Chang, D.-Y., and R. J. Maraia. Unpublished data.
   Google Scholar
• Cozzarelli, N. R., S. P. Gerrard, M. Schlissel, D. D. Brown, and D. F. Bogenhagen. 1983. Purified RNA polymerase III accuratelyand efficiently terminates transcription of 5S RNA genes. Cell 34:829–835.
   PubMed Web of Science ®Google Scholar
• Daniels, G. R., and P. L. Deininger. 1985. Integration site preferences of the Alu family and similar repetitive DNA sequences. Nucleic Acids Res. 13:8939–8954.
   PubMedGoogle Scholar
• Dieci, G., L. Duimio, F. Coda-Zabetta, K. U. Sprague, and S. Ottonello. 1993. A novel RNA polymerase III transcription factor fraction that is not required for template commitment. J. Biol. Chem. 268:11199–11207.
   PubMedGoogle Scholar
• Englander, E. W., A. P. Wolffe, and B. H. Howard. 1993. Nucleosome interactions with a human Alu element: transcriptional repression and effects of template methylation. J. Biol. Chem. 268:19565–19573.
   PubMed Web of Science ®Google Scholar
• Francoeur, A. M., E. K. L. Chan, J. I. Garrels, and M. B. Mathews. 1985. Characterization and purification of lupus antigen La, an RNA-binding protein. Mol. Cell. Biol. 5:586–590.
   PubMed Web of Science ®Google Scholar
• Geiduschek, E. P., and G. P. Tocchini-Valentini. 1988. Transcription by RNA polymerase III. Annu. Rev. Biochem. 57:873–914.
   PubMed Web of Science ®Google Scholar
• Goldberg, Y. P., J. M. Rommens, S. E. Andrew, G. B. Hutchinson, B. Lin, J. Theilmann, R. Graham, M. L. Glaves, E. Starr, H. McDonald, J. Nasir, K. Schappert, M. A. Kalchman, L. A. Clarke, and M. R. Hayden. 1993. Identification of an Alu retrotransposition event in close proximity to a strong candidate gene for Huntington's disease. Nature (London) 362:370–373.
   PubMed Web of Science ®Google Scholar
• Gottlieb, E., and J. A. Steitz. 1987. The mammalian La protein associates with known transcription components, p. 465–468. In W. S. Reznikoff et al. (ed.), RNA polymerase and the regulation of transcription. Elsevier, New York.
   Google Scholar
• Gottlieb, E., and J. A. Steitz. 1989. Function of the mammalian La protein: evidence for its action in transcription termination by RNA polymerase III. EMBO J. 8:851–861.
   PubMed Web of Science ®Google Scholar
• Gottlieb, E., and J. A. Steitz. 1989. The RNA binding protein La influences both the accuracy and the efficiency of RNA polymerase III transcription in vitro. EMBO J. 8:841–850.
   PubMedGoogle Scholar
• Hannon, G. J., A. Chubb, P. A. Maroney, G. Hannon, S. Altman, and T. W. Nilsen. 1991. Multiple cis-acting elements are required for RNA polymerase III transcription of the gene encoding Hl RNA, the RNA component of human RNase P. J. Biol. Chem. 266:22796–22799.
   PubMedGoogle Scholar
• Hendrick, J. P., S. L. Wolin, J. Rinke, M. R. Lerner, and J. A. Steitz. 1981. Ro small cytoplasmic ribonucleoproteins are a subclass of La ribonucleoproteins: further characterization of the Ro and La small ribonucleoproteins from uninfected mammalian cells. Mol. Cell. Biol. 1:1138–1149.
   PubMed Web of Science ®Google Scholar
• Hernandez, N., and A. M. Weiner. 1986. Formation of the 3′ end of U1 snRNA requires compatible snRNA promoter elements. Cell 47:249–258.
   PubMed Web of Science ®Google Scholar
• Hoffman, D. W., C. C. Query, B. L. Golden, S. W. White, and J. D. Keene. 1991. RNA-binding domain of the A protein component of the U1 small nuclear ribonucleoprotein analyzed by NMR spectroscopy is structurally similar to ribosomal proteins. Proc. Natl. Acad. Sci. USA 88:2495–2499.
   PubMedGoogle Scholar
• Howard, B. H., and K. Sakamoto. 1990. Alu interspersed repeats: selfish DNA or a functional gene family. New Biol. 2:759–770.
   PubMedGoogle Scholar
• Jagadeeswaran, P., B. G. Forget, and S. M. Weissman. 1981. Short interspersed repetitive DNA elements in eucaryotes: transposable DNA elements generated by reverse transcription of RNA Pol III transcripts? Cell 26:141–142.
   PubMed Web of Science ®Google Scholar
• Jahn, D., E. Wingender, and K. H. Seifart. 1987. Transcription complexes for various class III genes differ in parameters of formation and stability towards salt. J. Mol. Biol. 193:303–313.
   PubMedGoogle Scholar
• James, P., S. Whelen, and B. D. Hall. 1991. The RET1 gene of yeast encodes the second-largest subunit of RNA polymerase III. J. Biol. Chem. 266:5616–5624.
   PubMedGoogle Scholar
• Jelinek, W. R., and C. W. Schmid. 1982. Repetitive sequences in eukaryotic DNA and their expression. Annu. Rev. Biochem. 51:813–844.
   PubMed Web of Science ®Google Scholar
• Juttermann, R., K. Hosokawa, S. Kochanek, and W. Doerfler. 1991. Adenovirus type 2 VAI RNA transcription by polymerase III is blocked by sequence-specific methylation. J. Virol. 65:1735–1742.
   PubMedGoogle Scholar
• Kassavetis, G. A., D. L. Riggs, R. Negri, L. H. Nguyen, and E. P. Geiduschek. 1989. Transcription factor IIIB generates extended DNA interactions in RNA polymerase III transcription complexes on tRNA genes. Mol. Cell. Biol. 9:2551–2566.
   PubMed Web of Science ®Google Scholar
• Kenan, D. J. et al. Unpublished data.
   Google Scholar
• Kenan, D. J., and R. J. Maraia. Unpublished data.
   Google Scholar
• Kochanek, S., D. Renz, and W. Doerfler. 1993. DNA methylation in the Alu sequences of diploid and haploid primary human cells. EMBO J. 12:1141–1151.
   PubMed Web of Science ®Google Scholar
• Labuda, D., D. Sinnett, C. Richer, J.-M. Deragon, and G. Striker. 1991. Evolution of mouse Bl repeats: 7SL RNA folding pattern conserved. J. Mol. Evol. 32:405–414.
   PubMedGoogle Scholar
• Lassar, A. B., P. L. Martin, and R. G. Roeder. 1983. Transcription of class III genes: formation of preinitiation complexes. Science 222:740–748.
   PubMed Web of Science ®Google Scholar
• Lee, D. Y., J. J. Hayes, D. Pruss, and A. P. Wolffe. 1993. A positive role for histone acetylation in transcription factor access to nucleosomal DNA. Cell 72:1–20.
   Google Scholar
• Liu, W.-M., and C. W. Schmid. 1993. Proposed roles for DNA methylation in Alu transcriptional repression and mutational inactivation. Nucleic Acids Res. 21:1351–1359.
   PubMed Web of Science ®Google Scholar
• Maraia, R. 1991. The subset of mouse Bl (Alu-equivalent) sequences expressed as small processed cytoplasmic transcripts. Nucleic Acids Res. 19:5695–5702.
   PubMedGoogle Scholar
• Maraia, R. Unpublished data.
   Google Scholar
• Maraia, R., M. Zasloff, P. Plotz, and S. Adeniyi-Jones. 1988. Pathway of B1-Alu expression in microinjected oocytes: Xenopus laevis proteins associated with nuclear precursor and processed cytoplasmic RNAs. Mol. Cell. Biol. 8:4433–4440.
   PubMedGoogle Scholar
• Maraia, R. J., D.-Y. Chang, A. P. Wolffe, R. L. Vorce, and K. Hsu. 1992. The RNA polymerase III terminator used by a B1-Alu element can modulate 3′ processing of the intermediate RNA product. Mol. Cell. Biol. 12:1500–1506.
   PubMedGoogle Scholar
• Maraia, R. J., C. Driscoll, T. Bilyeu, K. Hsu, and G. J. Darlington. 1993. Multiple dispersed loci produce small cytoplasmic Alu RNA. Mol. Cell. Biol. 13:4233–4241.
   PubMed Web of Science ®Google Scholar
• Matera, A. G., U. Hellmann, and C. W. Schmid. 1990. A transpo- sitionally and transcriptionally competent Alu subfamily. Mol. Cell. Biol. 10:5424–5432.
   PubMedGoogle Scholar
• Mathews, M. B., and A. M. Francoeur. 1984. La antigen recognizes and binds to the 3′-oligouridylate tail of a small RNA. Mol. Cell. Biol. 4:1134–1140.
   PubMed Web of Science ®Google Scholar
• Mazabraud, A., D. Scherly, F. Müller, D. Rungger, and S. G. Clarkson. 1987. Structure and transcription termination of a lysine tRNA gene from Xenopus laevis. J. Mol. Biol. 195:835–845.
   PubMedGoogle Scholar
• Meerovitch, K. S., Y. V. Svitkin, H. S. Lee, F. Lejbkowicz, D. J. Kenan, E. K. L. Chan, V. I. Agol, J. D. Keene, and N. Sonenberg. 1993. La autoantigen enhances and corrects aberrant translation of poliovirus RNA in reticulocyte lysate. J. Virol. 67:3798–3807.
   PubMed Web of Science ®Google Scholar
• Muratani, K., T. Hada, Y. Yamamoto, T. Kaneko, Y. Shigeto, T. Ohue, J. Furuyama, and K. Higashino. 1991. Inactivation of the cholinesterase gene by Alu insertion: possible mechanism for human gene transposition. Proc. Natl. Acad. Sci. USA 88:11315–11319.
   PubMed Web of Science ®Google Scholar
• Neuman de Vegvar, H. E., E. Lund, and J. E. Dahlberg. 1986. 3′ end formation of U1 snRNA precursors is coupled to transcription from snRNA promoters. Cell 47:259–266.
   PubMed Web of Science ®Google Scholar
• Neznanov, N., I. S. Thorey, G. Cecena, and R. G. Oshima. 1993. Transcriptional insulation of the human keratin 18 gene in transgenic mice. Mol. Cell. Biol. 13:2214–2223.
   PubMedGoogle Scholar
• Neznanov, N. S., and R. G. Oshima. 1993. cis regulation of the keratin 18 gene in transgenic mice. Mol. Cell. Biol. 13:1815–1823.
   PubMedGoogle Scholar
• Paulson, K. E., and C. W. Schmid. 1986. Transcriptional inactivity of Alu repeats in HeLa cells. Nucleic Acids Res. 14:6145–6158.
   PubMed Web of Science ®Google Scholar
• Reddy, R., D. Henning, E. Tan, and H. Busch. 1983. Identification of a La protein binding site in a RNA polymerase III transcript (4.5 I RNA). J. Biol. Chem. 258:8352–8356.
   PubMedGoogle Scholar
• Rinke, J., and J. A. Steitz. 1982. Precursor molecules of both human 5S ribosomal RNA and transfer RNAs are bound by a cellular protein reactive with anti-La lupus antibodies. Cell 29:149–159.
   PubMed Web of Science ®Google Scholar
• Rosa, M. D., E. Gottlieb, M. R. Lerner, and J. A. Steitz. 1981. Striking similarities are exhibited by two small Epstein-Barr virus-encoded ribonucleic acids and the adenovirus-associated ribonucleic acids VAI and VAIL Mol. Cell. Biol. 1:785–796.
   Google Scholar
• Sakamoto, K., C. M. Fordis, C. D. Corsico, T. H. Howard, and B. H. Howard. 1991. Modulation of HeLa cell growth by transfected 7SL RNA and Alu gene sequences. J. Biol. Chem. 266:3031–3038.
   PubMedGoogle Scholar
• Sasaki-Tozawa, N., and R. J. Maraia. Unpublished data.
   Google Scholar
• Scherly, D., F. Stutz, N. Lin-Marq, and S. G. Clarkson. 1993. La proteins from Xenopus laevis cDNA cloning and developmental expression. J. Mol. Biol. 231:196–204.
   PubMedGoogle Scholar
• Schmid, C., and R. Maraia. 1992. Transcriptional regulation and transpositional selection of active SINE sequences. Curr. Opin. Genet. Dev. 2:874–882.
   PubMedGoogle Scholar
• Scott, R. W., and S. M. Tilghman. 1983. Transient expression of a mouse α-fetoprotein minigene: deletion analyses of promoter function. Mol. Cell. Biol. 3:1295–1309.
   PubMedGoogle Scholar
• Setzer, D. R., and D. D. Brown. 1985. Formation and stability of the 5 S RNA transcription complex. J. Biol. Chem. 260:2483–2492.
   PubMed Web of Science ®Google Scholar
• Stefano, J. E. 1984. Purified lupus antigen La recognizes an oligouridylate stretch common to the 3′ termini of RNA polymerase III transcripts. Cell 36:145–154.
   PubMed Web of Science ®Google Scholar
• Steinberg, T. H., D. E. Mathews, R. D. Durbin, and R. R. Burgess. 1990. Tagetitoxin: a new inhibitor of eukaryotic transcription by RNA polymerase III. J. Biol. Chem. 265:499–505.
   PubMedGoogle Scholar
• Steitz, J. A. 1989. Immunoprecipitation of ribonucleoproteins using autoantibodies. Methods Enzymol. 180:468–481.
   PubMedGoogle Scholar
• Terns, M. P., E. Lund, and J. E. Dahlberg. 1992. 3′-end-dependent formation of U6 small nuclear ribonucleoprotein particles in Xenopus laevis oocyte nuclei. Mol. Cell. Biol. 12:3032–3040.
   PubMed Web of Science ®Google Scholar
• Topfer, F., T. Gordon, and J. McCluskey. 1993. Characterization of the mouse autoantigen La (SS-B). J. Immunol. 150:3091–3100.
   PubMedGoogle Scholar
• Ullu, E., and A. M. Weiner. 1984. Human genes and pseudogenes for the 7SL RNA component of signal recognition particle. EMBO J. 3:3303–3310.
   PubMed Web of Science ®Google Scholar
• Van Arsdell, S. W., R. A. Denison, L. B. Bernstein, and A. M. Weiner. 1981. Direct repeats flank three small nuclear RNA pseudogenes in the human genome. Cell 26:11–17.
   PubMed Web of Science ®Google Scholar
• Wallace, M. R., L. B. Andersen, A. M. Saulino, P. E. Gregory, T. W. Glover, and F. S. Collins. 1991. A de novo Alu insertion results in neurofibromatosis type 1. Nature (London) 353:864–866.
   PubMedGoogle Scholar
• Watson, J. B., D. W. Chandler, and J. D. Gralla. 1984. Specific termination of in vitro transcription by calf thymus RNA polymerase III. Nucleic Acids Res. 12:5369–5384.
   PubMedGoogle Scholar
• Willis, I. M. 1993. RNA polymerase III genes, factors and transcriptional specificity. Eur. J. Biochem. 212:1–11.
   PubMedGoogle Scholar
• Wu, J., G. J. Grindlay, P. Bushel, L. Mendelsohn, and M. Allan. 1990. Negative regulation of the human epsilon-globin gene by transcriptional interference: role of an Alu repetitive element. Mol. Cell. Biol. 10:1209–1216.
   PubMedGoogle Scholar
• Young, P. R., R. W. Scott, D. H. Hamer, and S. M. Tilghman. 1982. Construction and expression in vivo of an internally deleted mouse a-fetoprotein gene: presence of a transcribed Alu-like repeat within the first intervening sequence. Nucleic Acids Res. 10:3099–3116.
   PubMedGoogle Scholar