Disease-Activated Transcription Factor: Allergic Reactions in Human Skin Cause Nuclear Translocation of STAT-91 and Induce Synthesis of Keratin K17

Refrences

• Barker, J. N. W. N., M. H. Allen, and D. M. MacDonald. 1989. The effect of in vivo interferon-gamma on the distribution of LFA-1 and ICAM-1 in normal human skin. J. Invest. Dermatol. 93: 439–442.
   PubMedGoogle Scholar
• Bell, E., B. Ivarsson, and C. Merrill. 1979. Production of a tissue-like structure by contraction of collagen lattices by human fibroblasts of different proliferative potential in vitro. Proc. Natl. Acad. Sci. USA 76: 1274–1278.
   PubMed Web of Science ®Google Scholar
• Bemerd, F., T. Magnaldo, I. M. Freedberg, and M. Blumenberg. 1993. Expression of the carcinoma-associated keratin K6 and the role of AP-1 proto-oncoproteins. Gene Expression 3: 187–199.
   PubMedGoogle Scholar
• Chang, E. H., J. Ridge, R. Black, Z.-Q. Zou, T. Masnyk, P. Noguchi, and J. B. Harford. 1987. Interferon-y induces altered oncogene expression and terminal differentiation in A431 cells. Proc. Soc. Exp. Biol. Med. 186: 319–326.
   PubMedGoogle Scholar
• Cooper, D., and T.-T. Sun. 1986. Monoclonal antibody analysis of bovine epithelial keratins. J. Biol. Chem. 261: 4646–4654.
   PubMed Web of Science ®Google Scholar
• Decker, T., D. J. Lew, and J. E. DarnellJr., 1991. Two distinct alpha-interferon-dependent signal transduction pathways may contribute to activation of transcription of the guanylate-binding protein gene. Mol. Cell. Biol. 11: 5147–5153.
   PubMedGoogle Scholar
• Decker, T., D. J. Lew, J. Mirkovitch, and J. E. DarnellJr., 1991. Cytoplasmic activation of GAF, an IFN-y-regulated DNA-binding factor. EMBO J. 10: 927–932.
   PubMed Web of Science ®Google Scholar
• Degitz, K., L. Lian-Jie, and S. W. Caughman. 1991. Cloning and characterization of the 5′-transcriptional regulatory region of the human intercellular adhesion molecule 1 gene. J. Biol. Chem. 266: 14024–14030.
   PubMed Web of Science ®Google Scholar
• de Jong, E. M. G. J., I. M. M. J. van Vlijmen, P. E. J. van Erp, F. C. S. Ramaekers, S. M. Troyanovski, and P. C. M. van de Kerhof. 1991. Keratin 17: a useful marker in anti-psoriatic therapies. Arch. Dermatol. Res. 283: 480–482.
   PubMedGoogle Scholar
• Dustin, M. L., K. H. Singer, D. T. Tuck, and T. A. Springer. 1988. Adhesion of T lymphoblasts to epidermal keratinocytes is regulated by intercellular adhesion molecule 1 (ICAM-1). J. Exp. Med. 167: 1323–1340.
   PubMed Web of Science ®Google Scholar
• Ebner, R., and R. Derynck. 1991. Epidermal growth factor and transforming growth factor-α: differential intracellular routing and processing of ligand-receptor complexes. Cell. Regul. 2: 599–612.
   PubMedGoogle Scholar
• Eron, L. J., F. Judson, S. Tucker, et al. 1986. Interferon therapy for condylomata acuminata. N. Engl. J. Med. 315: 1059–1064.
   PubMed Web of Science ®Google Scholar
• Flohr, T., U. Buwitt, B. Bonnekoh, T. Decker, and E. C. Böttger. 1992. Interferon-y regulates expression of a novel keratin class Igene. Eur. J. Immunol. 22: 975–979.
   PubMedGoogle Scholar
• Fu, X.-Y., C. Schindler, T. Improta, R. Aebersold, and J. E. DarnellJr., 1992. The proteins of ISGF-3, the interferon α-in- duced transcriptional activator, define a gene family involved in signal transduction. Proc. Natl. Acad. Sci. USA 89: 7840–7843.
   PubMed Web of Science ®Google Scholar
• Fu, X.-Y., and J.-J. Zhang. 1993. Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter. Cell 74: 1135–1145.
   PubMed Web of Science ®Google Scholar
• Gutch, M. J., C. Daly, and N. C. Reich. 1992. Tyrosine phosphorylation is required for activation of an α interferon-stimulated transcription factor. Proc. Natl. Acad. Sci. USA 89: 11411–11415.
   PubMed Web of Science ®Google Scholar
• Imam, A. M. A., A. M. Ackrill, T. C. Dale, I. M. Kerr, and G. R. Stark. 1990. Transcription factors induced by interferons α and y. Nucleic Acids Res. 18: 6573–6580.
   PubMed Web of Science ®Google Scholar
• Jiang, C.-K., H. S. Epstein, M. Tomic, I. M. Freedberg, and M. Blumenberg. 1990. Epithelial-specific keratin gene expression: identification of a 300 base-pair controlling segment. Nucleic Acids Res. 18: 247–253.
   PubMedGoogle Scholar
• Jiang, C.-K., H. S. Epstein, M. Tomic, I. M. Freedberg, and M. Blumenberg. 1991. Functional comparison of the upstream regulatory DNA sequences of four human epidermal keratin genes. J. Invest. Dermatol. 96: 162–167.
   PubMedGoogle Scholar
• Jiang, C. K., T. Magnaldo, M. Ohtsuki, I. M. Freedberg, F. Bemerd, and M. Blumenberg. 1993. EGF and TGFα specifically induce the activation- and hyperproliferation-associated keratins K#6 and K#16. Proc. Natl. Acad. Sci. USA 90: 6786–6790.
   PubMedGoogle Scholar
• Kaplan, G., M. D. Witmer, I. Nath, R. M. Steinman, S. Laal, H. K. Prasad, E. N. Sarno, U. Elvers, and Z. A. Cohn. 1986. Influence of delayed immune reactions on human epidermal keratinocytes. Proc. Natl. Acad. Sci. USA 83: 3469–3473.
   PubMedGoogle Scholar
• Khan, K. D., K. Shuai, G. Lindwall, S. E. Maher, J. E. DarnellJr., and A. L. M. Bothwell. 1993. Induction of the Ly-6A/E gene by both interferon α/β and y requires a DNA element to which a tyrosine phosphorylated 91 kDa protein binds. Proc. Natl. Acad. Sci. USA 90: 6806–6811.
   PubMed Web of Science ®Google Scholar
• Krueger, J. G., J. F. Krane, M. Carter, and A. B. Gottlieb. 1990. Role of growth factors, cytokines, and their receptors in the pathogenesis of psoriasis. J. Invest. Dermatol. 94: 135S–140S.
   PubMed Web of Science ®Google Scholar
• Kupper, T. S. 1990. Role of epidermal cytokines, p. 285–305. In J. J. Oppenheim, and E. M. Shevach (ed.), Immuno-physiology. The role of cells and cytokines in immunity and inflammation. Oxford University Press, New York.
   Google Scholar
• Levy, D., and J. E. DarnellJr., 1990. Interferon-dependent transcriptional activation: signal transduction without second messenger involvement? New Biol. 2: 923–928.
   PubMedGoogle Scholar
• Mirkovitch, J., T. Decker, and J. E. DarnellJr., 1992. Interferon induction of gene transcription analyzed by in vivo footprinting. Mol. Cell. Biol. 12: 1–9.
   PubMed Web of Science ®Google Scholar
• Nickoloff, B. J., C. E. M. Griffiths, and J. N. W. N. Barker. 1990. The role of adhesion molecules, chemotactic factors, and cytokines in inflammatory and neoplastic skin disease—1990 update. J. Invest. Dermatol. 94: 151S–157S.
   PubMedGoogle Scholar
• O'Guin, W. M., A. Schermer, and T.-T. Sun. 1985. Immunofluorescence staining of keratin filaments in cultured epithelial cells. J. Tissue Culture Methods 9: 12–128.
   Google Scholar
• Ohtsuki, T., S. Flanagan, I. M. Freedberg, and M. Blumenberg. 1993. A cluster of five nuclear proteins regulates keratin gene transcription. Gene Expression 3: 201–213.
   PubMedGoogle Scholar
• Pittelkow, M. R., R. J. CoffeyJr., and H. L. Moses. 1988. Keratinocytes produce and are regulated by transforming growth factors, p. 211–224. In L. M. Milstone, and R. L. Edelson (ed.), Endocrine, metabolic and immunologic functions of keratinocytes, vol. 548. New York Academy of Sciences, New York.
   Google Scholar
• Reid, L. E., A. H. Brasnett, C. S. Gilbert, A. C. G. Porter, D. R. Gewert, G. R. Stark, and I. M. Kerr. 1989. A single DNA response element can confer inducibility by both α- and y-interferons. Proc. Natl. Acad. Sci. USA 86: 840–844.
   PubMed Web of Science ®Google Scholar
• Ruff-Jamison, S., K. Chen, and S. Cohen. 1993. Induction by EGF and interferon-y of tyrosine phosphorylated DNA binding proteins in mouse liver nuclei. Science 261: 1733–1736.
   PubMed Web of Science ®Google Scholar
• Savtchenko, E. S., M. Tomic, R. Ivker, and M. Blumenberg. 1990. Three parallel linkage groups of human acidic keratin genes. Genomics 7: 394–407.
   PubMedGoogle Scholar
• Schindler, C., X.-Y. Fu, T. Improta, R. Aebersold, and J. E. DarnellJr., 1992. Proteins of transcription factor ISGF-3: one gene encodes the 91- and 84-kDa ISGF-3 proteins that are activated by interferon α. Proc. Natl. Acad. Sci. USA 89: 7836–7839.
   PubMed Web of Science ®Google Scholar
• Sen, G. C., and P. Lengyel. 1992. The interferon system. A bird's eye view of its biochemistry. J. Biol. Chem. 267: 5017–5020.
   Web of Science ®Google Scholar
• Shuai, K., C. Schindler, V. R. Prezioso, and J. E. DarnellJr., 1992. Activation of transcription by IFN-y: tyrosine phosphorylation of a 91-kD DNA binding protein. Science 258: 1808–1812.
   PubMed Web of Science ®Google Scholar
• Shuai, K., A. Ziemiecki, A. F. Wilks, A. G. Harpur, H. B. Sadowski, M. Z. Gilman, and J. E. Darnell. 1993. Polypeptide signalling to the nucleus through tyrosine and phosphorylation of Jak and Stat proteins. Nature (London) 366: 580–585.
   PubMed Web of Science ®Google Scholar
• Steinert, P. M., and D. R. Roop. 1988. Molecular and cellular biology of intermediate filaments. Annu. Rev. Biochem. 57: 593–625.
   PubMed Web of Science ®Google Scholar
• Troyanovski, S. M., R. E. Leube, and W. W. Franke. 1992. Characterization of the human gene encoding cytokeratin 17 and its expression pattern. Eur. J. Cell Biol. 59: 127–137.
   PubMedGoogle Scholar
• Velazquez, L., M. Fellous, G. R. Star, and S. Pellegrini. 1992. A protein tryosine kinase in the interferon α/β signaling pathway. Cell 70: 313–322.
   PubMed Web of Science ®Google Scholar
• Vilcek, J. 1990. Interferons, p. 3–38. In M. B. Sporn, and A. B. Roberts (ed.), Peptide growth factors and their receptors II. Springer-Verlag, New York.
   Google Scholar
• Wilson, K. C., and D. S. Feinbloom. 1992. Interferon y rapidly induces in human monocytes a DNA-binding factor that recognizes the γ response region within the promoter of the gene for the high-affinity Fey receptor. Proc. Natl. Acad. Sci. USA 89: 11964–11968.
   PubMedGoogle Scholar