Multidrug Resistance of DNA-Mediated Transformants is Linked to Transfer of the Human mdr1 Gene

LITERATURE CITED

• Akiyama, S.-L., A. Fojo, J. Hanover, I. Pastan, and M. M. Gottesman. 1985. Isolation and genetic characterization of human KB cell lines resistant to multiple drugs. Somatic Cell Genet. 11:117–126.
   Google Scholar
• Aviv, H., and P. Leder. 1972. Purification of biologically active globin messenger RNA by chromatography on oligothymidilic acid cellulose. Proc. Natl. Acad. Sci. USA 69:1408–1412.
   PubMed Web of Science ®Google Scholar
• Beck, W. T., T. J. Mueller, and L. R. Tanzer. 1974. Altered surface membrane glycoproteins in Vinca alkaloid-resistant human leukemic lymphoblasts. Cancer Res. 39:2070–2076.
   Google Scholar
• Biedler, J. C., and R. H. F. Peterson. 1981. Chemotherapeutic agents, p. 453–482. In A. C. Sarotoelli, J. S. Lazo, and J. R. Bertino (ed.), Molecular actions and targets for cancer. Academic Press, Inc., New York.
   Google Scholar
• Birnboim, H. C., and J. Doly. 1979. A rapid alkaline extraction procedure for screening recombinant plasmid DNA. Nucleic Acids Res. 7:1513–1523.
   PubMed Web of Science ®Google Scholar
• Chirgwin, J., A. Przybyla, R. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299.
   PubMed Web of Science ®Google Scholar
• Cornwell, M. M., A. R. Safa, R. L. Felsted, M. M. Gottesman, and I. Pastan. 1986. Membrane vesicles from multidrug-resistant human cancer cells contain a specific 150,000-170,000 dalton protein detected by photoaffinity labeling. Proc. Natl. Acad. Sci. USA 83:3847–3850.
   PubMed Web of Science ®Google Scholar
• Debenham, P. G., N. Kartner, L. Siminovitch, J. R. Riordan, and V. Ling. 1982. DNA-mediated transfer of multiple drug resistance and plasma membrane glycoprotein expression. Mol. Cell. Biol. 2:881–889.
   PubMed Web of Science ®Google Scholar
• Deininger, P. L., D. J. Jolly, C. M. Rubin, T. Friedmann, and C. W. Schmid. 1981. Base sequence studies of 300 nucleotide renatured repeated human DNA clones. J. Mol. Biol. 151:17–33.
   PubMed Web of Science ®Google Scholar
• Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
   PubMed Web of Science ®Google Scholar
• Fojo, A., J. Whang-Peng, M. M. Gottesman, and I. Pastan. 1985. Amplification of DNA sequences in human multidrug-resistant KB carcinoma cells. Proc. Natl. Acad. Sci. USA 82:7661–7665.
   PubMed Web of Science ®Google Scholar
• Fojo, A., R. Lebo, N. Shimizu, J. E. Chin, I. B. Roninson, G. T. Merlino, M. M. Gottesman, and I. Pastan. 1986. Localization of multidrug resistance-associated DNA sequences to human chromosome 7. Somatic Cell Mol. Genet. 12:415–420.
   PubMedGoogle Scholar
• Gros, P., J. Croop, I. Roninson, A. Varshavsky, and D. E. Housman. 1986. Isolation and characterization of DNA sequences amplified in multidrug resistant hamster cells. Proc. Natl. Acad. Sci. USA 83:337–341.
   PubMed Web of Science ®Google Scholar
• Gudkov, A. V., J. S. Massino, O. B. Chernova, and B. P. Kopnin. 1985. Gene amplification in Djungarian hamster cell lines possessing decreased plasma membrane permeability for colchicine and some other drugs. Chromosoma (Berlin) 92:16–24.
   PubMedGoogle Scholar
• Jnliano, R., and V. Ling. 1976. A surface glycoprotein modulating drug permeability in Chinese hamster ovary cell mutants. Biochem. Biophys. Acta 455:152–162.
   PubMedGoogle Scholar
• Ling, V. 1985. Multidrug-resistant mutants, p. 773–787. In M. M. Gottesman (ed.), Molecular cell genetics. John Wiley & Sons, Inc., New York.
   Google Scholar
• Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Rigby, P. W., M. Dieckmann, C. Rhodes, and P. Berg. 1977. Labeling deoxyribonucleic acid to high specific activity in vitro by nick-translation with DNA polymerase I. J. Mol. Biol. 113:237–251.
   PubMed Web of Science ®Google Scholar
• Riordan, J. R., K. Denchars, N. Kartner, M. Alon, J. Trent, and V. Ling. 1985. Amplification of P-glycoprotein genes in multidrug-resistant mammalian cell lines. Nature (London) 316:817–819.
   PubMed Web of Science ®Google Scholar
• Robertson, S. M., V. Ling, and C. P. Stanners. 1984. Co-amplification of double minute chromosomes, multiple drug resistance, and cell surface P-glycoprotein in DNA-mediated transformants of mouse cells. Mol. Cell. Biol. 4:500–506.
   PubMed Web of Science ®Google Scholar
• Roninson, I. B. 1983. Detection and mapping of homologous, repeated and amplified DNA sequences by DNA renaturation in agarose gels. Nucleic Acids Res. 11:5413–5431.
   PubMed Web of Science ®Google Scholar
• Roninson, I. B., H. T. Abelson, D. E. Housman, N. Howell, and A. Varshavsky. 1984. Amplification of specific DNA sequences correlates with multidrug resistance in Chinese hamster cells. Nature (London) 309:626–638.
   PubMed Web of Science ®Google Scholar
• Roninson, I. B., J. E. Chin, K. Choi, P. Gros, D. Housman, A. Fojo, D.-W. Shen, M. M. Gottesman, and I. Pastan. 1986. Isolation of the human mdr DNA sequences amplified in multidrug-resistant KB carcinoma cells. Proc. Natl. Acad. Sci. USA 83:4538–4542.
   PubMed Web of Science ®Google Scholar
• Shen, D.-W., A. Fojo, J. E. Chin, I. B. Roninson, N. Richert, I. Pastan, and M. M. Gottesman. 1986. Increased expression of the mdr1 gene in various human multidrug resistant cell lines can precede the gene amplification event. Science 232:643–645.
   PubMed Web of Science ®Google Scholar
• Shen, D.-W., C. Cardarelli, J. Hwang, M. Cornwell, N. Richert, S. Ishii, I. Pastan, and M. M. Gottesman. 1986. Multiply drug resistant human KB carcinoma cells independently selected for high-level resistance to colchicine, adriamycin or vinblastine show changes in expression of specific proteins. J. Biol. Chem. 261:7762–7770.
   PubMed Web of Science ®Google Scholar
• Southern, E. M. 1975. Detection of specific sequences among DNA fragments separated by gel electrophoresis. J. Mol. Biol. 98:503–517.
   PubMed Web of Science ®Google Scholar
• Southern, P. J., and P. Berg. 1982. Transformation of mammalian cells to antibiotic resistance with a bacterial gene under control of the SV40 early region promoter. J. Mol. Appl. Genet. 1:327–341.
   PubMedGoogle Scholar
• Wigler, M., R. Sweet, G. K. Sim, B. Wold, A. Pellicer, E. Lacey, T. Maniatis, S. Silverstein, and R. Axel. 1979. Transformation of mammalian cells with genes from procaryotes and eucaryotes. Cell 16:777–785.
   PubMed Web of Science ®Google Scholar