DNA-Binding Activities of the Drosophila melanogaster even-skipped Protein Are Mediated by Its Homeo Domain and Influenced by Protein Context

Literature Cited

• Akam, M. 1983. The location of Ultrabithorax transcripts in Drosophila tissue sections. EMBO J. 2:2075-2084.
   PubMedGoogle Scholar
• Akam, M. 1987. The molecular basis for metameric pattern in the Drosphila embryo. Development 101:1-22.
   PubMedGoogle Scholar
• Carroll, S. B., and M. P. Scott. 1986. Zygotically-active genes that affect the spatial expression of the fushi tarazu segmentation gene during early Drosophila embryogenesis. Cell 45:113-126.
   PubMedGoogle Scholar
• Desplan, C., J. Theis, and P. H. O’Farrell. 1985. The Drosophila developmental gene, engrailed, encodes a sequence-specific DNA binding activity. Nature (London) 318:630-635.
   PubMedGoogle Scholar
• DiNardo, S., J. M. Kuner, J. Theis, and P. H. O’Farrell. 1985. Development of embryonic pattern as revealed by accumulation of the nuclear engrailed protein. Cell 43:59-69.
   PubMedGoogle Scholar
• DiNardo, S., and P. H. O’Farrell. 1987. Establishment and refinement of segmental pattern in the Drosophila embryo: spatial control of engrailed expression by pair-rule genes. Genes Dev. 1:1212-1225.
   PubMedGoogle Scholar
• Fjose, A., W. McGinnis, and W. J. Gehring. 1985. Isolation of a homeo box-containing gene from the engrailed region of Drosophila and the spatial distribution of its transcripts. Nature (London) 313:284-289.
   PubMedGoogle Scholar
• Frasch, M., T. Hoey, C. Rushlow, H. Doyle, and M. Levine. 1987. Characterization and localization of the even-skipped protein of Drosophila. EMBO J. 6:749-759.
   PubMedGoogle Scholar
• Frigerio, G., M. Burri, D. Bopp, S. Baumgartner, and M. Noll. 1986. Structure of the segmentation gene paired and the Drosophila PRD gene set as part of a gene network. Cell 47:735-746.
   PubMedGoogle Scholar
• Garcia-Bellido, A. 1977. Homeotic and atavic mutations in insects. Am. Zool. 17:613-629.
   Google Scholar
• Gehring, W. J. 1987. Homeo boxes in the study of development. Science 236:1245-1252.
   PubMed Web of Science ®Google Scholar
• Harding, K., C. Rushlow, H. J. Doyle, T. Hoey, and M. Levine. 1986. Cross-regulatory interactions among pair-rule genes in Drosophila. Science 233:953-959.
   PubMedGoogle Scholar
• Harding, K., C. Wedeen, W. McGinnis, and M. Levine. 1985. Spatially regulated expression of homeotic gene expression in Drosophila. Science 229:1236-1242.
   PubMedGoogle Scholar
• Heberlein, U., B. England, and R. Tjian. 1985. Characterization of Drosophila transcription factors that activate the tandem promoters of the alcohol dehydrogenase gene. Cell 41:965-977.
   PubMedGoogle Scholar
• Hoey, T., and M. Levine. 1988. Divergent homeo box proteins recognize similar DNA sequences in Drosophila. Nature (London) 332:858-861.
   PubMedGoogle Scholar
• Ingham, P. W., N. E. Baker, and A. Martinez-Arias. 1988. Regulation of segment polarity genes in the Drosophila blastoderm by fushi tarazu and even-skipped. Nature (London) 331:73-75.
   PubMedGoogle Scholar
• Ingham, P. W., and A. Martinez-Arias. 1986. The correct activation of antennapedia and bithorax complex genes requires the fushi tarazu gene. Nature (London) 324:592-597.
   PubMedGoogle Scholar
• Kilcherr, F., S. Baumgartner, D. Bopp, and M. Noll. 1986. Isolation of the paired gene of Drosophila and its spatial expression during early embryogenesis. Cell 45:493-499.
   Google Scholar
• Kornberg, T., I. Siden, P. H. O’Farrell, and M. Simon. 1985. The engrailed locus of Drosophila: in situ localization of transcripts reveals compartment-specific expression. Cell 42:309-316.
   PubMedGoogle Scholar
• Laughon, A., and M. P. Scott. 1984. Sequence of a Drosophila segmentation gene: protein structure homology with DNA- binding proteins. Nature (London) 310:25-31.
   PubMedGoogle Scholar
• Lawrence, P. A., P. Johnston, P. Macdonald, and G. Struhl. 1987. Borders of parasegments are delimited by the fushi tarazu and even-skipped genes. Nature (London) 328:440-442.
   PubMedGoogle Scholar
• Levine, M., E. Hafen, R. Garber, and W. J. Gehring. 1983. Spatial distribution of Antennapedia transcripts during Drosophila development. EMBO J. 2:2037-2046.
   PubMedGoogle Scholar
• Levine, M., and K. Harding. 1987. Spatial regulation of homeo box gene expression in Drosophila p. 116-142. In N. Maclean (ed.), Oxford survey on eukaryotic genes, vol. 5. Oxford University Press, Oxford.
   Google Scholar
• Macdonald, P. M., P. W. Ingham, and G. Struhl. 1986. Isolation, structure, and expression of even-skipped: a second pairrule of Drosophila containing a homeo box. Cell 47:721-734.
   PubMedGoogle Scholar
• Maxam, A., and W. Gilbert. 1980. Sequencing end-labeled DNA. Methods Enzymol. 65:499-560.
   PubMedGoogle Scholar
• McGinnis, W., M. S. Levine, E. Hafen, A. Kuroiwa, and W. J. Gehring. 1984. A conserved DNA sequence in homeotic genes of the Drosophila Antennapedia and Bithorax gene complexes. Nature (London) 308:428-433.
   PubMedGoogle Scholar
• Nusslein-Volhard, C., H. Kluding, and G. Jurgens. 1985. Genes affecting the segmental organization of the Drosophila embryo. Cold Spring Harbor Symp. Quant. Biol. 50:145-154.
   PubMedGoogle Scholar
• Nusslein-Volhard, C., and E. Wieschaus. 1980. Mutations affecting segment number and polarity in Drosophila. Nature (London) 287:795-801.
   PubMed Web of Science ®Google Scholar
• Poole, S. J., L. M. Kauvar, B. Drees, and T. Kornberg. 1985. The engrailed locus of Drosophila: structural analysis of an embryonic transcript. Cell 40:37-43.
   PubMedGoogle Scholar
• Rosenberg, A. H., B. N. Lade, D.-S. Chui, S.-W. Lin, J. J. Dunn, and F. W. Studier. 1987. Vectors for selective expression of cloned DNAs by T7 RNA polymerase. Gene 56:125-135.
   PubMed Web of Science ®Google Scholar
• Rushlow, C., H. Doyle, T. Hoey, and M. Levine. 1987. Molecular characterization of the zerknullt region of the Antennapedia gene complex in Drosophila. Genes Dev. 1:1268-1279.
   PubMedGoogle Scholar
• Rushlow, C., K. Harding, and M. Levine. 1987. Hierarchical interactions among pattern forming genes in Drosophila. Developmental toxicology mechanisms and risks, Banbury report 26. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
   Google Scholar
• Scott, M. P., and S. B. Carroll. 1987. The segmentation and homeotic gene network in early Drosophila development. Cell 51:689-698.
   PubMedGoogle Scholar
• Shuey, D. J., and C. S. Parker. 1986. Bending of promoter DNA on binding of heat shock transcription factor. Nature (London) 323:459-461.
   PubMed Web of Science ®Google Scholar
• Struhl, G., and R. A. H. White. 1985. Regulation of the Ultrabithorax gene of Drosophila by other bithorax complex genes. Cell 43:507-516.
   PubMedGoogle Scholar
• Studier, F. W., and B. A. Moffatt. 1986. Use of bacteriophage T7 RNA polymerase to direct selective high-level expression of cloned genes. J. Mol. Biol. 189:113-130.
   PubMed Web of Science ®Google Scholar
• Wakimoto, B. T., F. R. Turner, and T. C. Kaufman. 1984. Defects in embryogenesis in mutants associated with the Anten- napedia gene complex of Drosophila melanogaster. Dev. Biol. 102:147-172.
   PubMedGoogle Scholar
• Wedeen, C., K. Harding, and M. Levine. 1986. Spatial regulation of antennapedia and bithorax gene expression by the Polycomb locus in Drosophila. Cell 44:739-748.
   PubMedGoogle Scholar
• Zoller, M. J., and M. Smith. 1984. Oligonucleotide-directed mutagenesis: a simple method using two oligonucleotide primers and a single-stranded DNA template. DNA 3:479-488.
   PubMedGoogle Scholar