0
Views
3
CrossRef citations to date
0
Altmetric
Research Article

Characterization of a Novel Anti-Peptide Antibody That Recognizes a Specific Conformation of the Platelet-Derived Growth Factor Receptor

, , &
Pages 3696-3702 | Received 26 Feb 1988, Accepted 31 May 1988, Published online: 31 Mar 2023

LITERATURE CITED

  • Antoniades, H. N., C. D. Scher, and C. D. Stiles. 1979. Purification of human platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 76:1809–1813.
  • Barany, G., and R. B. Merrifield. 1980. p. 1-284. In E. Gross and J. Meienhofer (ed.), The peptides: analysis, synthesis and biology. Academic Press, Inc., New York.
  • Bishayee, S., A. H. Ross, R. Womer, and C. D. Scher. 1986. Purified human platelet-derived growth factor receptor has ligand-stimulated tyrosine kinase activity. Proc. Natl. Acad. Sci. USA 83:6756–6760.
  • Claesson-Welsh, L., L. Ronnstrand, and C.H. Heldin. 1987. Biosynthesis and intracellular transport of the receptor for platelet-derived growth factor. Proc. Natl. Acad. Sci. USA 84:8796–8800.
  • Cummings, R. D., A. M. Soderquist, and G. Carpenter. 1985. The oligosaccharide moieties of the epidermal growth factor receptor in A-431 cells: presence of complex-type N-linked chains that contain terminal N-acetylgalactosamine residues. J. Biol. Chem. 260:11944–11952.
  • Daniel, T. O., P. M. Tremble, A. R. Frackelton, and L. T. Williams. 1985. Purification of the platelet-derived growth factor receptor by using an anti-phosphotyrosine antibody. Proc. Natl. Acad. Sci. USA 82:2684–2687.
  • Deuel, T. F., J. S. Huang, R. T. Profitt, J. U. Baenziger, D. Chang, and B. B. Kennedy. 1981. Human platelet-derived growth factor. Purification and resolution into two active protein fractions. J. Biol. Chem. 256:8896–8899.
  • Doolittle, R. F., M. W. Hunkapiller, L. E. Hood, S. G. Devare, K. C. Robbins, C. A. Aaronson, and H. N. Antoniades. 1983. Simian sarcoma virus onc gene, v-sis, is derived from the gene (or genes) encoding a platelet-derived growth factor. Science 221:275–277.
  • Frackelton, A. R., A. H. Ross, and H. N. Eisen. 1983. Characterization and use of monoclonal antibodies for isolation of phosphotyrosyl proteins from retrovirus-transformed cells and growth factor-stimulated cells. Mol. Cell. Biol. 3:1343–1352.
  • Hart, C. E., R. A. Seifert, R. Ross, and D. F. Bowen-Pope. 1987. Synthesis, phosphorylation, and degradation of multiple forms of the platelet-derived growth factor receptor studied using a monoclonal antibody. J. Biol. Chem. 262:10780–10785.
  • Heldin, C. H., B. Westermark, and A. Wasteson. 1981. Specific receptors for platelet-derived growth factor on cells derived from connective tissue and glia. Proc. Natl. Acad. Sci. USA 78:3664–3668.
  • Kaufmann, S. H., C. M. Wing, and J. H. Shaper. 1987. The erasable Western blot. Anal. Biochem. 161:89–95.
  • Keating, M. T., and L. T. Williams. 1987. Processing of the platelet-derived growth factor receptor: biosynthetic and degradation studies using antireceptor antibodies. J. Biol. Chem. 262:7932–7937.
  • Krupp, M. N., D. T. Connolly, and M. D. Lane. 1982. Synthesis, turnover, and down-regulation of epidermal growth factor receptors in human A431 epidermoid carcinoma cells and skin fibroblasts. J. Biol. Chem. 257:11489–11496.
  • Laskey, R. A., and A. D. Mills. 1975. Quantitative film detection of 3H and 14C in polyacrylamide gels by fluorography. Eur J. Biochem. 56:335–341.
  • Olson, T. S., and M. D. Lane. 1987. Post-translational acquisition of insulin binding activity by the insulin pro-receptor: correlation to recognition by auto-immune antibody. J. Biol. Chem. 262:6816–6822.
  • Raines, E. W., and R. Ross. 1982. Platelet-derived growth factor. I. High yield purification and evidence for multiple forms. J. Biol. Chem. 257:5154–5160.
  • Ronnett, G. V., G. Tennekoon, V. P. Knutson, and M. D. Lane. 1983. Kinetics of insulin receptor transit to and removal from the plasma membrane: effect of insulin-induced down-regulation in 3T3-L1 adipocytes. J. Biol. Chem. 258:283–290.
  • Ronnstrand, L., M. P. Beckmann, B. Faulders, A. Ostman, B. Ek, and C. H. Heldin. 1987. Purification of the receptor for platelet-derived growth factor from porcine uterus. J. Biol. Chem. 262:2929–2932.
  • Scher, C. D., L. J. Engle, W. M. Eberenz, K. Ganguly, and W. Wharton. 1986. Dissociation of cellular transformation from platelet-derived growth factor independence. J. Cell. Physiol. 126:333–340.
  • Scher, C. D., W. J. Pledger, P. Martin, H. N. Antoniades, and C. D. Stiles. 1978. Transforming viruses directly reduce the cellular growth requirement for a platelet-derived growth factor. J. Cell. Physiol. 97:371–380.
  • Stoschek, C. M., and G. Carpenter. 1984. Down regulation of epidermal growth factor receptors: direct demonstration of receptor degradation in human fibroblasts. J. Cell Biol. 98:1048–1053.
  • Waterfield, M. D., G. F. Scrace, N. Whittle, P. Stroobant, A. Johnsson, A. Wasteson, B. Westermark, C. H. Heldin, J. S. Huang, and T. F. Deuel. 1983. Platelet-derived growth factor is structurally related to the putative transforming protein p28sis of simian sarcoma virus. Nature (London) 304:35–39.
  • Yarden, Y., J. A. Escobedo, W.-J. Kuang, T. L. Yang-Feng, T. O. Daniel, P. M. Tremble, E. Y. Chen, M. E. Ando, R. N. Harkins, U. Francke, V. A. Fried, A. Ullrich, and L. T. Williams. 1986. Structure of the receptor for platelet-derived growth factor helps define a family of closely related growth factor receptors. Nature (London) 323:226–232.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.