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Gene Expression

Structure of an Ectodermally Expressed Sea Urchin Metallothionein Gene and Characterization of Its Metal-Responsive Region

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Pages 5445-5455 | Received 20 May 1989, Accepted 01 Sep 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Akhurst, R. J., F. J. Calzone, J. J. Lee, R. J. Britten, and E. H. Davidson. 1987. Structure and organization of the Cylll actin gene subfamily of the sea urchin, Strongylocentrotus purpuratus. J. Mol. Biol. 194:193–203.
  • Andersen, R. D., B. W. Birren, S. J. Taplitz, and H. R. Herschman. 1986. Rat metallothionein-1 structural gene and three pseudogenes, one of which contains 5′-regulatory sequences. Mol. Cell. Biol. 6:302–314.
  • Angerer, L. M., G. Kawczynski, D. G. Wilkinson, M. Nemer, and R. C. Angerer. 1986. Spatial patterns of metallothionein mRNA expression in the sea urchin embryo. Dev. Biol. 116:543–547.
  • Benson, S., H. Sucov, L. Stephens, E. Davidson, and F. Wilt. 1987. A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. I. Authentication of the cloned gene and its developmental expression. Dev. Biol. 120:499–506.
  • Bond-Matthews, B., and N. Davidson. 1988. Transcription from each of the Drosophilia act5c leader exons is driven by a separate functional promoter. Gene 62:289–300.
  • Breathnach, R., and P. Chambon. 1981. Organization and expression of eukaryotic split genes coding for proteins. Annu. Rev. Biochem. 50:349–383.
  • Britten, R. J., A. Cetta, and E. H. Davidson. 1978. The singlecopy DNA sequence polymorphism of the sea urchin Strongylocentrotus purpuratus. Cell 15:1175–1186.
  • Brunk, C. F., K. C. Jones, and T. W. Janies. 1979. Assay for nanogram quantities of DNA in cellular homogenates. Anal. Biochem. 92:497–500.
  • Calzone, F. J., N. Theze, P. Thiebaud, R. L. Hill, R. J. Britten, and E. H. Davidson. 1988. Developmental appearance of factors that bind specifically to cis-regulatory sequences of a gene expressed in the sea urchin embryo. Genes Dev. 2:1074–1088.
  • Conlon, R. A., F. Tufaro, and Β. P. Brandhorst. 1987. Post- transcriptional restriction of gene expression in sea urchin interspecies hybrid embryos. Genes Dev. 1:337–346.
  • Cox, K. H., L. M. Angerer, J. J. Lee, E. H. Davidson, and R. C. Angerer. 1986. Cell lineage-specific programs of expression of multiple actin genes during sea urchin embryogenesis. J. Mol. Biol. 188:159–172.
  • Cullotta, V. C., and D. H. Hamer. 1989. Fine mapping of a mouse metallothionein gene metal response element. Mol. Cell. Biol. 9:1376–1380.
  • Davidson, E. H.. 1989. Lineage-specific gene expression and the regulative capacities of the sea urchin embryo: a proposed mechanism. Development 105:421–445.
  • DePamphilis, M. L., S. A. Herman, E. Martinez-Salas, L. E. Chalifour, D. O. Wirak, D. Y. Cupo, and M. Miranda. 1988. Microinjecting DNA into mouse ova to study DNA replication and gene expression and to produce transgenic animals. BioTechniques 6:662–680.
  • Devereux, J., P. Haeberli, and O. Smithies. 1984. A comprehensive set of sequence analysis programs for the VAX. Nucleic Acid Res. 12:387–395.
  • Flytzanis, C. N., R. J. Britten, and E. H. Davidson. 1987. Ontogenic activation of a fusion gene introduced into sea urchin eggs. Proc. Natl. Acad. Sci. USA 84:151–155.
  • Foss, K., and W. H. McClain. 1987. Rapid site-specific mutagenesis in plasmids. Gene 59:285–290.
  • Franks, R. R., B. R. Hough-Evans, R. J. Britten, and E. H. Davidson. 1988. Direct introduction of cloned DNA into the sea urchin zygote nucleus, and fate of injected DNA. Development 102:287–299.
  • Furey, W. F., A. H. Robbins, L. L. Clancy, D. R. Winge, B. C. Wang, and C. D. Stout. 1986. Crystal structure of Cd, Zn metallothionein. Science 231:704–710.
  • Glanville, N., D. M. Durnam, and R. D. Palmiter. 1981. Structure of mouse metallothionein-I gene and its mRNA. Nature (London) 292:267–269.
  • Gorman, C. M., L. F. Moffat, and Β. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Hamer, D. H.. 1986. Metallothionein. Annu. Rev. Biochem. 55:913–951.
  • Hardin, S. H., C. D. Carpenter, P. E. Hardin, A. M. Bruskin, and W. H. Klein. 1985. Structure of the Sped gene encoding a major calcium-binding protein in the embryonic ectoderm of the sea urchin, Strongylocentrotus purpuratus. J. Mol. Biol. 186:243–255.
  • Harlow, P., and M. Nemer. 1987. Developmental and tissuespecific regulation of β-tubulin gene expression in the embryo of the sea urchin Strongylocentrotus purpuratus. Genes Dev. 1:147–160.
  • Haslinger, A., and M. Karin. 1985. Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element. Proc. Natl. Acad. Sci. USA 82:8572–8576.
  • Heguy, A., A. West, R. I. Richards, and M. Karin. 1986. Structure and tissue-specific expression of the human metallothionein IB gene. Mol. Cell. Biol. 6:2149–2157.
  • Hinegardner, R.. 1974. Cellular DNA content of the Echinodermata. Comp. Biochem. Physiol. 49B:219–226.
  • Hough-Evans, B. R., R. J. Britten, and E. H. Davidson. 1988. Mosaic incorporation and regulated expression of an exogenous fusion gene in the sea urchin embryo. Dev. Biol. 129:198–208.
  • Hunt, C. T., Y. Boulanger, S. W. Fesik, and I. M. Armitage. 1984. NMR analysis of the structure and metal sequestering properties of metallothioneins. Environ. Health Perspect. 54:135–145.
  • Jones, N. C., P. W. J. Rigby, and E. B. Ziff. 1988. Trani-acting protein factors and the regulation of eukaryotic transcription: lessons from studies on DNA tumor viruses. Genes Dev. 2:267–281.
  • Karin, M., A. Haslinger, A. Heguy, T. Dietlin, and T. Cooke. 1987. Metal-responsive elements act as positive modulators of human metallothionein-IIA enhancer activity. Mol. Cell. Biol. 7:606–613.
  • Karin, M., and R. I. Richards. 1982. Human metallothionein genes—primary structure of the metallothionein-II gene and a related processed gene. Nature (London) 299:797–802.
  • Katula, K. S., B. R. Hough-Evans, R. J. Britten, and E. H. Davidson. 1987. Ontogenic expression of a Cyl actin fusion gene injected into sea urchin eggs. Development 101:437–447.
  • Kedesch, T., and P. Berg. 1986. Effects of the position of the simian virus 40 enhancer on expression of multiple transcription units in a single plasmid. Mol. Cell. Biol. 6:2593–2601.
  • Lee, J. J., R. J. Shott, S. J. Rose III, T. L. Thomas, R. J. Britten, and E. H. Davidson. 1984. Sea urchin actin gene subtypes. Gene number, linkage and evolution. J. Mol. Biol. 172:149–176.
  • Lynn, D. A., L. M. Angerer, A. M. Bruskin, W. H. Klein, and R. C. Angerer. 1983. Localization of a family of mRNAs in a single cell type and its precursors in sea urchin embryos. Proc. Natl. Acad. Sci. USA 80:2656–2660.
  • Maroni, G., E. Otto, and D. Lastowski-Perry. 1986. Molecular and cytogenetic characterization of a metallothionein gene of Drosophila. Genetics 112:493–504.
  • McClay, D. R., and A. F. Chambers. 1978. Identification of four classes of cell surface antigens appearing at gastrulation in sea urchin embryos. Dev. Biol. 63:179–186.
  • McMahon, A. P., C. N. Flytzanis, B. R. Hough-Evans, K. S. Katula, R. J. Britten, and E. H. Davidson. 1985. Introduction of cloned DNA into sea urchin egg cytoplasm: replication and persistence during embryogenesis. Dev. Biol. 108:420–430.
  • Mueller, P. R., S. J. Salser, and B. Wold. 1988. Constitutive and metal-inducible protein:DNA interactions at the mouse metallothionein I promoter examined by in vivo and in vitro footprinting. Genes Dev. 2:412–427.
  • Nemer, M., E. C. Travaglini, E. Rondinelli, and J. D'Alonzo. 1984. Developmental regulation, induction and embryonic tissue specificity of sea urchin metallothionein gene expression. Dev. Biol. 102:471–482.
  • Nemer, M., D. G. Wilkinson, E. C. Travaglini, E. J. Sternberg, and T. R. Butt. 1985. Sea urchin metallothionein sequence: key to an evolutionary diversity. Proc. Natl. Acad. Sci. USA 82:4992–4994.
  • Nielson, Κ. B., and D. R. Winge. 1985. Independence of the domains of metallothionein in metal binding. J. Biol. Chem. 260:8698–8701.
  • Otto, E., J. M. Allen, J. E. Young, R. D. Palmiter, and G. Maroni. 1987. A DNA segment controlling metal-regulated expression of the Drosophila melanogaster metallothionein gene Mtn. Mol. Cell. Biol. 7:1710–1715.
  • Palmiter, R. D.. 1987. Molecular biology of metallothionein gene expression. Experientia Suppl. 52:63–80.
  • Peterson, M. G., and J. F. Mercer. 1986. Structure and regulation of the sheep metallothionein-Ia gene. Eur. J. Biochem. 160:579–585.
  • Richards, R. I., A. Heguy, and M. Karin. 1984. Structural and functional analysis of the human metallothionein-IA gene: differential induction by metal ions and glucocorticoids. Cell 37:263–272.
  • Searle, P. F., B. L. Davison, G. W. Stuart, T. M. Wilkie, G. Norstedt, and R. D. Palmiter. 1984. Regulation, linkage, and sequence of mouse metallothionein I and II genes. Mol. Cell. Biol. 4:1221–1230.
  • Searle, P. F., G. W. Stuart, and R. D. Palmiter. 1985. Building a metal-responsive promoter with synthetic regulatory elements. Mol. Cell. Biol. 5:1480–1489.
  • Searle, P. F., G. W. Stuart, and R. D. Palmiter. 1987. Metal regulatory elements of the mouse metallothionein-I gene. Experientia Suppl. 52:407–414.
  • Sharp, P. A., A. J. Berk, and S. M. Berget. 1980. Transcription maps of adenovirus. Methods Enzymol. 65:750–768.
  • Stuart, G. W., P. F. Searle, H. Y. Chen, R. L. Brinster, and R. D. Palmiter. 1984. A 12-base-pair DNA motif that is repeated several times in metallothionein gene promoters confers metal regulation to a heterologous gene. Proc. Natl. Acad. Sci. USA 81:7318–7322.
  • Stuart, G. W., P. F. Searle, and R. D. Palmiter. 1985. Identification of multiple metal regulatory elements in mouse metal-lothionein-I promoter by assaying synthetic sequences. Nature (London) 317:828–831.
  • Sucov, H. M., S. Benson, J. J. Robinson, R. J. Britten, F. Wilt, and E. H. Davidson. 1987. A lineage-specific gene encoding a major matrix protein of the sea urchin embryo spicule. II. Structure of the gene and derived sequence of the protein. Dev. Biol. 120:507–519.
  • Sucov, H. M., B. R. Hough-Evans, R. R. Franks, R. J. Britten, and E. H. Davidson. 1988. A regulatory domain that directs lineage-specific expression of a skeletal matrix protein gene in the sea urchin embryo. Genes Dev. 2:1238–1250.
  • Thiele, D. J., and D. H. Hamer. 1986. Tandemly duplicated upstream control sequences mediate copper-induced transcription of the Saccharomyces cerevisiae copper-metallothionein gene. Mol. Cell. Biol. 6:1158–1163.
  • Varshney, U., N. Jahroudi, R. Foster, and L. Gedamu. 1986. Structure, organization, and regulation of human metallothionein IF gene: differential and cell-type specific expression in response to heavy metals and glucocorticoids. Mol. Cell. Biol. 6:26–37.
  • Wilkinson, D. G., and M. Nemer. 1987. Metallothionein genes MTa and MTb expressed under distinct quantitative and tissuespecific regulation in sea urchin embryos. Mol. Cell. Biol. 7:48–58.
  • Zafarullah, M., K. Bonham, and L. Gedamu. 1988. Structure of the rainbow trout metallothionein B gene and characterization of its metal-responsive region. Mol. Cell. Biol. 8:4469–4476.

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