2
Views
2
CrossRef citations to date
0
Altmetric
Gene Expression

Use of a Glucocorticoid-Inducible Promoter for Expression of Herpes Simplex Virus Type 1 Glycoprotein gC1, a Cytotoxic Protein in Mammalian Cells

, , , , , , & show all
Pages 2303-2314 | Received 22 Nov 1988, Accepted 23 Feb 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Arsenakis, M., G. Campadelli-Fiume, and B. Roizman. 1988. Regulation of glycoprotein D synthesis: does alpha 4, the major regulatory protein of herpes simplex virus 1, regulate late genes both positively and negatively? J. Virol. 62:148–158.
  • Arsenakis, M., L. F. Tomasi, V. Speziali, B. Roizman, and G. Campadelli-Fiume. 1986. Expression and regulation of glycoprotein C gene of herpes simplex virus 1 resident in a clonal L-cell line. J. Virol. 58:367–376.
  • Berman, P. W., D. Dowbenko, and L. A. Lasky. 1983. Detection of antibodies to herpes simplex virus with a continuous cell line expressing cloned glycoprotein D. Science 222:524–527.
  • Blochlinger, K., and H. Diggelmann. 1984. Hygromycin B phosphotransferase as a selectable marker for DNA transfer experiments with higher eucaryotic cells. Mol. Cell. Biol. 4:2929–2931.
  • Buetti, E., and H. Diggelmann. 1981. Cloned mouse mammary tumor virus DNA is biologically active in transfected mouse cells and its expression is stimulated by glucocorticoid hormones. Cell 23:335–345.
  • Buetti, E., and H. Diggelmann. 1983. Glucocorticoid regulation of mouse mammary tumor virus: identification of a short essential DNA region. EMBO J. 2:1423–1429.
  • Buetti, E., and B. Kuhnel. 1986. Distinct sequence elements involved in the glucocorticoid regulation of the mouse mammary tumor virus promoter identified by linker scanning mutagenesis. J. Mol. Biol. 190:379–389.
  • Campadelli-Fiume, G., M. Arsenakis, F. Farabegoli, and B. Roizman. 1988. Entry of herpes simplex virus 1 in BJ cells that constitutively express viral glycoprotein D is by endocytosis and results in degradation of the virus. J. Virol. 62:159–167.
  • Cohen, G. H., B. Dietzschold, M. Ponce de Leon, D. Long, E. Golub, A. Varrichio, L. Pereira, and R. J. Eisenberg. 1984. Localization and synthesis of an antigenic determinant of herpes simplex virus glycoprotein D that stimulates production of neutralizing antibody. J. Virol. 49:102–108.
  • Cohen, G. H., W. C. Wilcox, D. L. Sodora, D. Long, J. Z. Levin, and R. J. Eisenberg. 1988. Expression of herpes simplex virus type 1 glycoprotein D deletion mutants in mammalian cells. J. Virol. 62:1932–1940.
  • Darbre, P. D., and R. J. B. King. 1987. Progression to steroid insensitivity can occur irrespective of the presence of functional steroid receptors. Cell 51:521–528.
  • Doerfler, W., K.-D. Langner, I. Kruczek, L. Vardimon, and D. Renz. 1984. Specific promoter methylations cause gene inactivation, p. 221–247. In A. Razira, H. Cedar, and A. D. Riggs (ed.), DNA methylation: biochemical and biological significance. Springer-Verlag, New York.
  • Eisenberg, R. J., M. Ponce de Leon, H. M. Friedman, L. F. Fries, M. M. Frank, J. C. Hastings, and G. H. Cohen. 1987. Complement component C3b binds directly to purified glycoprotein C of herpes simplex virus types 1 and 2. Microb. Pathogen. 3:423–435.
  • Ellis, N., E. Keitges, S. M. Gartler, and M. Rocchi. 1987. High-frequency reactivation of X-linked genes in Chinese hamster x human hybrid cells. Somat. Cell Mol. Genet. 13:191–204.
  • Fasel, N., K. Pearson, E. Buetti, and H. Diggelmann. 1982. The region of mouse mammary tumor virus DNA containing the long terminal repeat includes a long coding sequence and signals for hormonally regulated transcription. EMBO J. 1:3–7.
  • Firzlaff, J. M., and H. Diggelmann. 1984. Dexamethasone increases the number of RNA polymerase II molecules transcribing integrated mouse mammary tumor virus DNA and flanking mouse sequences. Mol. Cell. Biol. 4:1057–1062.
  • Friedman, H. M., G. H. Cohen, R. J. Eisenberg, C. A. Seidel, and D. B. Cines. 1984. Glycoprotein C of herpes simplex virus 1 acts as a receptor for the C3b component of complement on infected cells. Nature (London) 309:633–635.
  • Friedman, H. M., J. C. Glorioso, G. H. Cohen, J. C. Hastings, S. L. Harris, and R. J. Eisenberg. 1986. Binding of complement component C3b to glycoprotein gC of herpes simplex virus type 1: mapping of binding sites and demonstration of conserved C3b binding in low-passage clinical isolates. J. Virol. 60:470–475.
  • Fries, L. F., H. M. Friedman, G. H. Cohen, R. J. Eisenberg, C. H. Hammer, and M. M. Frank. 1986. Glycoprotein C of herpes simplex virus 1 is an inhibitor of the complement cascade. J. Immunol. 137:1636–1641.
  • Frink, R. J., R. Eisenberg, G. Cohen, and E. K. Wagner. 1983. Detailed analysis of the portion of the herpes simplex virus type 1 genome encoding glycoprotein C. J. Virol. 45:634–647.
  • Fuller, A. O., and P. G. Spear. 1987. Antiglycoprotein D antibodies that permit adsorption but block infection by herpes simplex virus 1 prevent virion-cell fusion at the cell surface. Proc. Natl. Acad. Sci. USA 84:5454–5458.
  • Gehring, U.. 1986. Genetics of glucocorticoid receptors. Mol. Cell. Endocrinol. 48:89–96.
  • Gompels, U., and A. Minson. 1986. The properties and sequence of glycoprotein H of herpes simplex virus type 1. Virology 153:230–247.
  • Graham, F. L., and A. J. van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus DNA. Virology 52:456–467.
  • Groner, B., N. Kennedy, U. Rahmsdorf, P. Herrlich, A. Van Ooyen, and N. E. Hynes. 1981. Introduction of a proviral mouse mammary tumor virus gene and a chimaeric MMTV-thymidine kinase gene into L cells results in their glucocorticoid responsive expression, p. 217–228. In J. E. Dumont, J. Nunez, and G. Schultz (ed.). Hormones and cell regulation, vol. 6. Elsevier/North-Holland Biomedical Press, Amsterdam.
  • Haslinger, A., and M. Karin. 1985. Upstream promoter element of the human metallothionein-IIA gene can act like an enhancer element. Proc. Natl. Acad. Sci. USA 82:8572–8576.
  • Holland, T. C., F. L. Homa, S. D. Marlin, M. Levin, and J. Glorioso. 1984. Herpes simplex virus type 1 glycoprotein C- negative mutants exhibit multiple phenotypes, including secretion of truncated glycoproteins. J. Virol. 52:566–574.
  • Huang, A. L., M. C. Ostrowski, D. Berard, and G. L. Hager. 1981. Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus. Cell 27:245–255.
  • Hynes, N., A. J. J. Van Ooyen, N. Kennedy, P. Herrlich, H. Ponta, and B. Groner. 1983. Subfragments of the large terminal repeat cause glucocorticoid-responsive expression of the mouse mammary tumor virus and of an adjacent gene. Proc. Natl. Acad. Sci. USA 80:3637–3641.
  • Hynes, N. E., N. Kennedy, U. Rahmsdorff, and B. Groner. 1981. Hormone-responsive expression of the endogenous proviral gene of mouse mammary tumor virus after molecular cloning and gene transfer into cultured cells. Proc. Natl. Acad. Sci. USA 78:2038–2042.
  • Jakobovits, E. B., J. E. Majors, and H. E. Varmus. 1984. Hormonal regulation of the Rous sarcoma virus src gene via a heterologous promoter defines a threshold dose for cellular transformation. Cell 38:757–765.
  • Jones, P. A., S. M. Taylor, T. Mohandas, and L. J. Shapiro. 1982. Cell cycle-specific reactivation of an inactive X-chromo- some locus by 5-azadeoxycytidine. Proc. Natl. Acad. Sci. USA 79:1215–1219.
  • Klessig, D. F., D. E. Brough, and V. Cleghon. 1984. Introduction. stable integration, and controlled expression of a chimeric adenovirus gene whose product is toxic to the recipient human cell. Mol. Cell. Biol. 4:1354–1361.
  • Lee, F., R. Mulligan, P. Berg, and G. Ringold. 1981. Glucocorticoids regulate expression of dihydrofolate reductase cDNA in mouse mammary tumor virus chimaeric plasmids. Nature (London) 294:228–232.
  • Levinson, B., G. Khoury, G. V. Woude, and P. Gruss. 1982. Activation of SV40 genome by 72-base pair tandem repeats of Moloney sarcoma virus. Nature (London) 295:568–572.
  • Majors, J., and H. E. Varmus. 1983. A small region of the mouse mammary tumor virus long terminal repeat confers glucocorticoid hormone regulation on a linked heterologous gene. Proc. Natl. Acad. Sci. USA 80:5866–5870.
  • Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Manservigi, R., P. G. Spear, and A. Buchan. 1977. Cell fusion induced by herpes simplex virus is promoted and suppressed by different viral glycoproteins. Proc. Natl. Acad. Sci. USA 74:3913–3917.
  • Mayo, K. E., R. Warren, and R. D. Palmiter. 1982. The mouse metallothionein-1 gene is transcriptionally regulated by cadmium following transfection into human and mouse cells. Cell 29:99–108.
  • McNearney, T. A., C. Odell, V. M. Holers, P. Spears, and J. P. Atkinson. 1987. Herpes simplex virus glycoproteins gC-1 and gC-2 bind to the third component of complement and provide protection against complement-mediated neutralization of viral infectivity. J. Exp. Med. 166:1525–1535.
  • Midgeon, B. R., J. Axelman, and A. H. Beggs. 1988. Effect of ageing on reactivation of the human X-linked HPRT locus. Nature (London) 335:93–96.
  • Miksicek, R., A. Heber, W. Schmid, U. Danesch, G. Posseckert, M. Beato, and G. Schutz. 1986. Glucocorticoid responsiveness of the transcriptional enhancer of Moloney murine sarcoma virus. Cell 46:283–290.
  • Noble, A. G., G. T.-Y. Lee, R. Sprague, M. L. Parish, and P. G. Spear. 1983. Anti-gD monoclonal antibodies inhibit cell fusion induced by herpes simplex virus type 1. Virology 129:218–224.
  • Northrop, J. P., M. Danielsen, and G. M. Ringold. 1986. Analysis of glucocorticoid unresponsive cell variants using a mouse glucocorticoid receptor complementary DNA clone. J. Biol. Chem. 261:11064–11070.
  • Pachel, C., R. L. Burke, L. L. Stuve, L. Sanchez-Pescador, G. Van Nest, F. Masiarz, and D. Dina. 1987. Expression of cell- associated and secreted forms of herpes simplex virus type 1 glycoprotein gB in mammalian cells. J. Virol. 61:315–325.
  • Papkoff, J., and G. M. Ringold. 1984. Use of the mouse mammary tumor virus long terminal repeats to promote steroid- inducible expression of v-mos. J. Virol. 52:420–430.
  • Raptis, L., H. Lamfrom, and T. L. Benjamin. 1985. Regulation of cellular phenotype and expression of polyomavirus middle T antigen in rat fibroblasts. Mol. Cell. Biol. 5:2476–2485.
  • Rosenthal, K. L., J. R. Smiley, S. South, and D. C. Johnson. 1987. Cells expressing herpes simplex virus glycoprotein gC but not gB, gD, or gE are recognized by murine virus-specific cytotoxic T lymphocytes. J. Virol. 61:2438–2447.
  • Ruyechan, W. T., L. S. Morse, D. M. Knipe, and B. Roizman. 1979. Molecular genetics of herpes simplex virus. II. Mapping of the major viral glycoproteins and of the genetic loci specifying the social behavior of the infected cells. J. Virol. 29:677–697.
  • Sarmiento, M., M. Haffey, and P. G. Spear. 1979. Membrane proteins specified by herpes simplex viruses. III. Role of glycoprotein VP7 (B2) in virion infectivitv. J. Virol. 29:1149–1158.
  • Schorderet, D. F., E. A. Keitges, P. M. Dubois, and S. M. Gartler. 1988. Inactivation and reactivation of sex-linked steroid sulfatase gene in murine cell culture. Somat. Cell Mol. Genet. 14:113–131.
  • Seidel-Dugan, C., M. Ponce de Leon, H. M. Friedman, L. F. Fries, M. M. Frank, G. H. Cohen, and R. J. Eisenberg. 1988. C3b receptor activity on transfected cells expressing glycoprotein C of herpes simplex virus types 1 and 2. J. Virol. 62:4027–1036.
  • Smiley, M. L., and H. M. Friedman. 1985. Binding of complement component C3b to glycoprotein C is modulated by sialic acid on herpes simplex virus type 1-infected cells. J. Virol. 55:857–861.
  • Su, H. K., and R. J. Courtney. 1988. Inducible expression of herpes simplex virus type 2 glycoprotein gene gG-2 in a mammalian cell line. J. Virol. 62:3668–3674.
  • Van Beveren, C., F. van Staaten, J. A. Galleshaw, and I. M. Verma. 1981. Nucleotide sequence of the genome of a murine sarcoma virus. Cell 27:97–108.
  • Van der Hoorn, F. A., and V. Muller. 1985. Differential transformation of C3H10T1/2 cells by v-mos: sequential expression of transformation parameters. Mol. Cell. Biol. 5:2204–2211.
  • Van der Hoorn, F., E. Hulsebos, A. J. M. Berns, and H. J. P. Bloemers. 1982. Molecularly cloned c-mos (rat) is biologically active. EMBOJ. 11:1313–1317.
  • Wagner, E. K.. 1985. Individual HSV transcripts: characterization of specific genes, p. 45–104. In B. Roizman (ed.), The herpesviruses, vol. 3. Plenum Publishing Corp., New York.
  • Weis, J. H., and J. G. Seidman. 1985. The expression of the major histocompatibility antigens under the metallothionein gene promoter control. J. Immunol. 134:1999–2003.
  • Wurm, F. M., K. A. Gwinn, and R. E. Kingston. 1986. Inducible overproduction of the mouse c-myc protein in mammalian cells. Proc. Natl. Acad. Sci. USA 83:5414–5418.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.