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Chromosome Structure and Dynamics

Chromatin Loop Structure of the Human X Chromosome: Relevance to X Inactivation and CpG Clusters

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Pages 2322-2331 | Received 02 Dec 1988, Accepted 21 Feb 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Alcalay, M., and D. Toniolo. 1988. CpG islands of the X chromosome are gene associated. Nucleic Acids Res. 16:9527–9543.
  • Anson, D. S., K. H. Choo, D. J. G. Rees, F. Giannelli, K. Gould, J. A. Huddleston, and G. G. Brownlee. 1984. The gene structure of human anti-haemophilic factor IX. EMBO J. 3:1053–1060.
  • Barr, M. L., and E. G. Bertram. 1949. A morphological distinction between neurones of the male and female, and the behaviour of the nucleolar satellite during accelerated nucleoprotein synthesis. Nature (London) 163:676–677.
  • Bird, A. P.. 1986. CpG-rich islands and the function of DNA methylation. Nature (London) 321:209–213.
  • Bishop, D. F., R. Kornreich, and R. J. Desnick. 1988. Structural organization of the human alpha-galactosidase A gene: further evidence for the absence of a 3′ untranslated region. Proc. Natl. Acad. Sci. USA 85:3903–3907.
  • Chimera, J. A., and P. R. Musich. 1985. The association of the interspersed repetitive KpnI sequences with the nuclear matrix. J. Biol. Chem. 260:9373–9379.
  • Ciejek, E. M., J. L. Nordstrom, M.-J. Tsai, and B. W. O'Malley. 1982. Ribonucleic acid precursors are associated with the chicken oviduct nuclear matrix. Biochemistry 21:4945–4953.
  • Ciejek, E. M., M. J. Tsai, and B. W. O'Malley. 1983. Actively transcribed genes are associated with the nuclear matrix. Nature (London) 306:607–609.
  • Cockerill, P. N., and W. T. Garrard. 1986. Chromosomal loop anchorage of the kappa immunoglobulin gene occurs next to the enhancer in a region containing topoisomerase II sites. Cell 44:273–282.
  • Cook, P. R., and I. A. Brazell. 1980. Mapping sequences in loops of nuclear DNA by their progressive detachment from the nuclear cage. Nucleic Acids Res. 8:2895–2906.
  • Cook, P. R., J. Lang, A. Hayday, L. Lania, M. Fried, D. J. Chiswell, and J. A. Wyke. 1982. Active viral genes in transformed cells lie close to the nuclear cage. EMBO J. 1:447–452.
  • Cooper, D. N., M. H. Taggart, and A. P. Bird. 1983. Unmethylated domains in vertebrate DNA. Nucleic Acids Res. 11:647–658.
  • Davies, K. E., P. Briand, G. Lonasescu, R. Williamson, C. Brown, C. Cavard, and L. Cathelineau. 1985. Gene for OTC: characterization and linkage to Duchenne muscular dystrophy. Nucleic Acids Res. 13:155–165.
  • Feinberg, A. P., and B. Vogelstein. 1983. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal. Biochem. 132:6–13.
  • Gasser, S. M., and U. K. Laemmli. 1986. The organisation of chromatin loops: characterization of a scaffold attachment site. EMBO J. 5:511–518.
  • Gasser, S. M., and U. K. Laemmli. 1986. Cohabitation of scaffold binding regions with upstream/enhancer elements of three developmentally regulated genes of D. melanogaster. Cell 46:521–530.
  • Gasser, S. M., and U. K. Laemmli. 1988. A glimpse at chromosomal order. Trends Genet. 3:16–22.
  • German, J.. 1962. DNA synthesis in human chromosomes. Trans. N.Y. Acad. Sci. 24:395–407.
  • Graves, J. A. M., and S. M. Gartler. 1986. Mammalian X chromosome inactivation: testing the hypothesis of transcriptional control. Somat. Cell. Mol. Genet. 12:275–280.
  • Hata, A., T. Tsuzuki, K. Shimada, M. Takiguchi, M. Mori, and I. Matsuda. 1986. Isolation and characterization of the human ornithine transcarbamylase gene: structure of the 5′-end region. J. Biochem. 100:717–725.
  • Jarman, A. P., and D. R. Higgs. 1988. Nuclear scaffold attachment sites in the human globin gene complexes. EMBO J. 7:3337–3344.
  • Kas, E., and L. A. Chasin. 1987. Anchorage of the Chinese hamster dihydrofolate reductase gene to the nuclear scaffold occurs in an intragenic region. J. Mol. Biol. 198:677–692.
  • Kaslow, D. C., and B. R. Migeon. 1987. DNA methylation stabilizes X chromosome inactivation in eutherians but not in marsupials: evidence for multistep maintenance of mammalian X dosage compensation. Proc. Natl. Acad. Sci. USA 84:6210–6214.
  • Keith, D. H., J. Singer-Sam, and A. D. Riggs. 1986. Active X chromosome DNA is unmethylated at eight CCGG sites clustered in a guanine-plus-cytosine-rich island at the 5′ end of the gene for phosphoglycerate kinase. Mol. Cell. Biol. 6:4122–4125.
  • Keppel, F.. 1986. Transcribed human ribosomal RNA genes are attached to the nuclear matrix. J. Mol. Biol. 187:15–21.
  • Lyon, M. F.. 1972. X chromosome inactivation and developmental patterns in mammals. Biol. Rev. 42:1–35.
  • Martini, G., D. Toniolo, T. Vulliamy, L. Luzzatto, R. Dono, G. Viglietto, G. Paonessa, M. D'Urso, and M. G. Persico. 1986. Structural analysis of the X-linked gene encoding human glucose 6-phosphate dehydrogenase. EMBO J. 5:1849–1855.
  • McCarry, J. R., and K. Thomas. 1987. Human testis-specific PGK gene lacks introns and possesses characteristics of a processed gene. Nature (London) 326:501–505.
  • McCready, S. J., J. Goodwin, D. W. Mason, I. A. Brazell, and P. R. Cook. 1980. DNA is replicated at the nuclear cage. J. Cell Sci. 46:365–386.
  • Michelson, A. M., C. C. F. Blake, S. T. Evans, and S. H. Orkin. 1985. Structure of the human phosphoglycerate kinase gene and the intron-mediated evolution and dispersal of the nucleotide- binding domain. Proc. Natl. Acad. Sci. USA 82:6965–6969.
  • Michelson, A. M., G. A. P. Bruns, C. C. Morton, and S. H. Orkin. 1985. The human phosphoglycerate kinase multigene family. J. Biol. Chem. 260:6982–6992.
  • Migeon, B. R., J. Axelman, and G. Stetten. 1988. Clonal evolution in human lymphoblast cultures. Am. J. Hum. Genet. 42:742–747.
  • Mirkovitch, J., M. E. Mirault, and U. K. Laemmli. 1984. Organization of the higher-order chromatin loop: specific DNA attachment sites on nuclear scaffold. Cell 39:223–232.
  • Mirkovitch, J., P. Spierer, and U. K. Laemmli. 1986. Genes and loops in 320,000 base-pairs of the Drosophila melanogaster chromosome. J. Mol. Biol. 190:255–258.
  • Nguyen, C., P. Pontarotti, D. Birnbaum, G. Chimini, J. A. Rey, J. F. Mattei, and B. R. Jordan. 1987. Large scale physical mapping in the q27 region of the human X chromosome: the coagulation factor IX gene and the mcf-2 transforming sequence are separated by at most 270 kilobase pairs and are surrounded by several HTF islands. EMBO J. 6:3285–3289.
  • Persico, M. G., G. Viglietto, G. Martini, D. Toniolo, G. Paonessa, C. Moscatelli, R. Dono, T. Vulliamy, L. Luzzatto, and M. D'Urso. 1986. Isolation of human glucose-6-phosphate dehydrogenase (G6PD) cDNA clones: primary structure of the protein and unusual 5′ non-coding region. Nucleic Acids Res. 14:2511–2522.
  • Robinson, S. L., B. D. Nelkin, and B. Vogelstein. 1982. The ovalbumin gene is associated with the nuclear matrix of chicken oviduct cells. Cell 28:99–106.
  • Ruta-Cullen, C., P. Hubberman, D. C. Kaslow, and B. R. Migeon. 1986. Comparison of factor IX methylation on human active and inactive X chromosomes: implications for X inactivation and transcription of tissue-specific genes. EMBO J. 5:2223–2229.
  • Sander, M., and T. S. Hsieh. 1985. Drosophila topoisomerase II double-strand DNA cleavage: analysis of DNA sequence homology at the cleavage site. Nucleic Acids Res. 13:1057–1072.
  • Singer-Sam, J., R. L. Simmer, D. H. Keith, L. Shively, M. Teplitz, K. Itakura, S. M. Gartler, and A. D. Riggs. 1983. Isolation of a cDNA clone for human X-linked 3-phosphoglyc- erate kinase by use of a mixture of synthetic oligodeoxyribonucleotides as a detection probe. Proc. Natl. Acad. Sci. USA 80:802–806.
  • Small, D., B. Nelkin, and B. Vogelstein. 1982. Nonrandom distribution of repeated DNA sequences with respect to supercoiled loops and the nuclear matrix. Proc. Natl. Acad. Sci. USA 79:5911–5915.
  • Small, D., B. Nelkin, and B. Vogelstein. 1985. The association of transcribed genes with the nuclear matrix of Drosophila cells during heat shock. Nucleic Acids Res. 13:2413–2430.
  • Small, D., and B. Vogelstein. 1985. The anatomy of supercoiled loops in the Drosophila 7F locus. Nucleic Acids Res. 13:7703–7713.
  • Spitzner, J. R., and M. T. Muller. 1988. A consensus sequence for cleavage by vertebrate DNA topoisomerase II. Nucleic Acids Res. 16:5533–5556.
  • Tani, K., J. Singer-Sam, M. Munns, and A. Yoshida. 1985. Molecular cloning and structure of an autosomal processed gene for human phosphoglycerate kinase. Gene 35:11–18.
  • Toniolo, D., G. Martini, B. R. Migeon, and R. Dono. 1988. Expression of the G6PD locus on the human X chromosome is associated with demethylation of three CpG islands within 100 kb of DNA. EMBO J. 7:401–406.
  • Tsuji, S., B. M. Martin, D. C. Kaslow, B. R. Migeon, P. V. Choudary, B. K. Stubblefield, J. A. Mayor, G. J. Murray, J. A. Barranger, and E. I. Ginns. 1987. Signal sequence and DNA- mediated expression of human lysosomal alpha-galactosidase A. Eur. J. Biochem. 165:275–280.
  • Vogelstein, B., D. M. Pardoll, and D. S. Coffey. 1980. Supercoiled loops and eucaryotic DNA replication. Cell 22:79–85.
  • Wolf, S. F., S. Dintzis, D. Toniolo, G. Persico, K. D. Lunnen, J. Axelman, and B. R. Migeon. 1984. Complete concordance between glucose-6-phosphate dehydrogenase activity and hypomethylation of 3′ CpG clusters: implications for X chromosome dosage compensation. Nucleic Acids Res. 12:9333–9348.
  • Wolf, S. F., D. J. Jolly, K. D. Lunnen, T. Friedmann, and B. R. Migeon. 1984. Methylation of the hypoxanthine phosphoribosyltransferase locus on the human X chromosome: implications for X-chromosome inactivation. Proc. Natl. Acad. Sci. USA 81:2806–2810.
  • Wolf, S. F., and B. R. Migeon. 1985. Clusters of CpG dinucleotides implicated by nuclease hypersensitivity as control elements of housekeeping genes. Nature (London) 314:467–469.

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