Regulation of Mouse CYP1A1 Gene Expression by Dioxin: Requirement of Two cis-Acting Elements during Induction

LITERATURE CITED

• Bernhard, H. P., G. J. Darlington, and F. H. Ruddle. 1973. Expression of liver phenotypes in cultured mouse hepatoma cells: synthesis and secretion of serum albumin. Dev. Biol. 35:83–96.
   PubMedGoogle Scholar
• Davidson, L., J. H. Xiao, R. Rosales, A. Staub, and P. Chambon. 1988. The HeLa cell protein TEF-1 binds specifically and cooperatively to two SV40 enhancer motifs of unrelated sequence. Cell 54:931–942.
   PubMedGoogle Scholar
• Denison, M. S., J. M. Fisher, and J. P. Whitlock, Jr.. 1988. Inducible, receptor-dependent protein-DNA interactions at a dioxin-responsive transcriptional enhancer. Proc. Natl. Acad. Sci. USA 85:2528–2532.
   PubMed Web of Science ®Google Scholar
• Fromenthal, C., M. Kanno, H. Nomiyama, and P. Chambon. 1988. Cooperativity and hierarchical levels of functional organization in the SV40 enhancer. Cell 54:943–953.
   PubMedGoogle Scholar
• Dignam, J. D., R. M. Lobowitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
   PubMed Web of Science ®Google Scholar
• Fujisawa-Sehara, A., K. Sogawa, C. Nishii, and Y. Fujii-Kuriyama. 1986. Regulatory DNA elements localized remotely upstream from the drug-metabolizing cytochrome P-450c gene. Nucleic Acids Res. 14:1465–1477.
   PubMed Web of Science ®Google Scholar
• Fujisawa-Sehara, A., K. Sogawa, M. Yamane, and Y. Fujii-Kuriyama. 1987. Characterization of xenobiotic responsive elements upstream from the drug-metabolizing cytochrome P-450c gene: a similarity to glucocorticoid regulatory elements. Nucleic Acids Res. 15:4179–4191.
   PubMed Web of Science ®Google Scholar
• Fujisawa-Sehara, A., M. Yamane, and Y. Fujii-Kuriyama. 1988. A DNA-binding factor specific for xenobiotic responsive elements of P-450c gene exists as a cryptic form in cytoplasm: its possible translocation to nucleus. Proc. Natl. Acad. Sci. USA 85:5859–5863.
   PubMed Web of Science ®Google Scholar
• Gilman, M. Z., R. N. Wilson, and R. A. Weinberg. 1986. Multiple protein-binding sites in the 5′-flanking region regulate c-fos expression. Mol. Cell. Biol. 6:4305–4316.
   PubMed Web of Science ®Google Scholar
• Gonzalez, F. J., and D. W. Nebert. 1985. Autoregulation plus upstream positive and negative control regions associated with transcriptional activation of the mouse P1450 gene. Nucleic Acids Res. 13:7269–7288.
   PubMed Web of Science ®Google Scholar
• Gonzalez, F. J., R. H. Tukey, and D. W. Nebert. 1984. Structural gene products of the Ah locus: transcriptional regulation of cytochrome P-1450 and P-3450 mRNA levels by 3-methylchol- anthrene. Mol. Pharmacol. 26:117–121.
   PubMed Web of Science ®Google Scholar
• Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
   PubMed Web of Science ®Google Scholar
• Griffith, J., A. Hochschild, and M. Ptashne. 1986. DNA loops induced by cooperative binding of repressor. Nature (London) 322:750–752.
   PubMed Web of Science ®Google Scholar
• Hai, T., M. Horikoshi, R. G. Roeder, and M. R. Green. 1988. Analysis of the role of the transcription factor ATF in the assembly of a functional preinitiation complex. Cell 54:1043–1051.
   PubMed Web of Science ®Google Scholar
• Hankinson, O., R. D. Andersen, B. Birren, F. Sander, M. Negishi, and D. W. Nebert. 1985. Mutations affecting the regulation of transcription of the cytochrome P1-450 gene in the mouse Hepa-1 cell line. J. Biol. Chem. 260:1790–1795.
   PubMed Web of Science ®Google Scholar
• Horikoshi, M., T. Hai, Y.-S. Lin, M. R. Green, and R. G. Roeder. 1988. Transcription factor ATF interacts with the TATA factor to facilitate establishment of a preinitiation complex. Cell 54:1033–1042.
   PubMed Web of Science ®Google Scholar
• Israel, D. L., and J. P. Whitlock, Jr.. 1984. Regulation of cytochrome P-1450 gene transcription by 2,3,7,8-tetrachlorobi- denzo-p-dioxin in wild type and variant mouse hepatoma cells. J. Biol. Chem. 259:5400–5402.
   PubMed Web of Science ®Google Scholar
• Jones, P. B. C., L. K. Durrin, D. R. Galeazzi, and J. P. Whitlock, Jr.. 1986. Control of cytochrome P1-450 gene expression: analysis of a dioxin-responsive enhancer system. Proc. Natl. Acad. Sci. USA 83:2802–2806.
   PubMed Web of Science ®Google Scholar
• Jones, P. B. C., A. G. Miller, D. I. Israel, D. R. Galeazzi, and J. P. Whitlock, Jr.. 1984. Biochemical and genetic analysis of variant mouse hepatoma cells which overtranscribe the cytochrome P1-450 gene in response to 2,3,7,8-tetrachlorodibenzo- p-dioxin. J. Biol. Chem. 259:12357–12363.
   PubMedGoogle Scholar
• Kimura, S., F. J. Gonzalez, and D. W. Nebert. 1986. Tissuespecific expression of the mouse dioxin-inducible P1450 and P3450 genes: differential transcriptional activation and mRNA stability in liver and extrahepatic tissues. Mol. Cell. Biol. 6:1471–1477.
   PubMed Web of Science ®Google Scholar
• Kouri, R. E., C. E. McKinney, D. J. Slomiany, D. R. Snodgrass, N. P. Wray, and T. L. McLemore. 1982. Positive correlation between high aryl hydrocarbon hydroxylase activity and primary lung cancer as analyzed in cryopreserved lymphocytes. Cancer Res. 42:5030–5037.
   PubMed Web of Science ®Google Scholar
• Legraverend, C., R. R. Hannah, H. J. Eisen, I. S. Owens, D. W. Nebert, and O. Hankinson. 1982. Regulatory gene product of the Ah locus: characterization of receptor mutations among mouse hepatoma clones. J. Biol. Chem. 257:6402–6407.
   PubMed Web of Science ®Google Scholar
• Liebermann, D., B. Hoffman-Liebermann, A. B. Troutt, L. Kedes, and S. N. Cohen. 1986. Sequences from sea urchin TU transposons are conserved among multiple eucaryotic species, including humans. Mol. Cell. Biol. 6:218–226.
   PubMedGoogle Scholar
• Maxam, A., and W. Gilbert. 1980. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65:499–560.
   PubMedGoogle Scholar
• Nebert, D. W.. 1988. Genes encoding drug-metabolizing enzymes: possible role in human disease, p. 45–64. In A. D. Woodhead, M. A. Bender, and R. C. Leonard (ed.). Phenotypic variation in populations. Plenum Publishing Corp., New York.
   Google Scholar
• Nebert, D. W., and F. J. Gonzalez. 1987. P450 genes: structure, evolution and regulation. Annu. Rev. Biochem. 56:945–993.
   PubMed Web of Science ®Google Scholar
• Nebert, D. W., and J. E. Jones. 1989. Regulation of the mammalian cytochrome P1-450 (CYP1A1) gene. Int. J. Biochem. 21:243–252.
   PubMedGoogle Scholar
• Nebert, D. W., D. R. Nelson, M. Adesnik, M. J. Coon, R. W. Estabrook, F. J. Gonzalez, F. P. Guengerich, I. C. Gunsalus, E. F. Johnson, B. Kemper, W. Levin, I. R. Phillips, R. Sato, and M. R. Waterman. 1989. The P450 gene superfamily. Update on the naming of new genes and nomenclature of chromosomal loci. DNA 8:1–13.
   PubMedGoogle Scholar
• Neuhold, L. A., F. J. Gonzalez, A. K. Jaiswal, and D. W. Nebert. 1986. Dioxin-inducible enhancer region upstream from the mouse P1450 gene and interaction with a heterologous SV40 promoter. DNA 5:403–411.
   PubMedGoogle Scholar
• Okey, A. B., G. P. Bondy, M. E. Mason, G. F. Kahl, H. J. Eisen, T. M. Guenthner, and D. W. Nebert. 1979. Regulatory gene product of the Ah locus: characterization of the cytosolic inducer-receptor complex and evidence for its nuclear translocation. J. Biol. Chem. 254:11015–11023.
   PubMedGoogle Scholar
• Parker, B. A., and G. R. Stark. 1979. Regulation of simian virus 40 transcription: sensitive analysis of the RNA species present early in infections by virus or viral DNA. J. Virol. 31:360–369.
   PubMed Web of Science ®Google Scholar
• Peterson, C. L., K. Orth, and K. L. Calame. 1986. Binding in vitro of multiple cellular proteins to immunoglobulin heavychain enhancer DNA. Mol. Cell. Biol. 6:4168–4178.
   PubMed Web of Science ®Google Scholar
• Pfeifer, K., T. Prezant, and L. Guarente. 1987. Yeast HAP1 activator binds to two upstream activation sites of different sequence. Cell 49:19–27.
   PubMedGoogle Scholar
• Poland, A., and J. Knutson. 1982. 2,3,7,8-Tetrachlorodibenzo- p-dioxin and related halogenated aromatic hydrocarbons: examination of the mechanism of toxicity. Annu. Rev. Pharmacol. Toxicol. 22:517–554.
   PubMed Web of Science ®Google Scholar
• Prywes, R., and R. G. Roeder. 1986. Inducible binding of a factor to the c-fos enhancer. Cell 47:777–784.
   PubMed Web of Science ®Google Scholar
• Ptashne, M.. 1986. Gene regulation by proteins acting nearby and at a distance. Nature (London) 322:697–701.
   PubMed Web of Science ®Google Scholar
• Robertson, M.. 1987. Gene regulation: specificity and flexibility. Nature (London) 327:464–466.
   PubMedGoogle Scholar
• Schleif, R.. 1987. Why should DNA loop? Nature (London) 327:369–370.
   PubMed Web of Science ®Google Scholar
• Sen, R., and D. Baltimore. 1988. Multiple nuclear factors interact with the immunoglobulin enhancer sequences. Cell 46:705–716.
   Google Scholar
• Shirayoshi, Y., J. I. Miyazaki, P. A. Burke, K. Hamada, E. Appella, and K. Ozato. 1987. Binding of multiple nuclear factors to the 5′ upstream regulatory element of the murine major histocompatibility class I gene. Mol. Cell. Biol. 7:4542–4548.
   PubMedGoogle Scholar
• Siebenlist, U., R. Simpson, and W. Gilbert. 1980. E. coli RNA polymerase interacts homologously with two different promoters. Cell 20:269–281.
   PubMed Web of Science ®Google Scholar
• Vinson, C. R., K. L. LaMarco, P. F. Johnson, W. H. Landshulz, and S. L. McKnight. 1988. In situ detection of sequence-specific DNA binding activity specified by a recombinant bacteriophage. Genes & Dev. 2:801–806.
   PubMedGoogle Scholar