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Gene Expression

The First Intron of the 4F2 Heavy-Chain Gene Contains a Transcriptional Enhancer Element That Binds Multiple Nuclear Proteins

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Pages 2588-2597 | Received 22 Dec 1988, Accepted 16 Mar 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Alcover, A., D. Ramarli, N. E. Richardson, H.-C. Chang, and E. L. Reinherz. 1987. Functional and molecular aspects of human T lymphocyte activation via T3-Ti and T11 pathways. Immunol. Rev. 95:5–36.
  • Angel, P., E. A. Allegretto, S. T. Okino, K. Hattori, W. J. Boyle, T. Hunter, and M. Karin. 1988. Oncogene jun encodes a sequence-specific trans-activator similar to AP-1. Nature (London) 332:166–171.
  • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor. Cell 49:729–739.
  • Bender, T. P., C. B. Thompson, and W. M. Kuehl. 1987. Differential expression of c-myb mRNA in murine B lymphomas by a block to transcription elongation. Science 237:1473–1476.
  • Bentley, D., and M. Groudine. 1986. A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells. Nature (London) 321:702–706.
  • Bohmann, D., T. J. Bos, A. Admon, T. Nishimura, P. K. Vogt, and R. Tjian. 1987. Human proto-oncogene c-jun encodes a DNA binding protein with structural and functional properties of transcription factor AP-1. Science 238:1386–1392.
  • Chiu, R., W. J. Boyle, J. Meek, T. Smeal, T. Hunter, and M. Karin. 1988. The c-Fos protein interacts with c-Jun/AP-1 to stimulate transcription of AP-1 responsive genes. Cell 54:541–552.
  • Chiu, R., M. Imagawa, R. J. Imbra, J. R. Bockoven, and M. Karin. 1987. Multiple cis- and trans-acting elements mediate the transcriptional response to phorbol esters. Nature (London) 329:648–651.
  • Cotner, T., J. M. Williams, L. Christenson, H. M. Shapiro, T. B. Strom, and J. Strominger. 1983. Simultaneous flow cytometric analysis of human T cell activation antigen expression and DNA content. J. Exp. Med. 157:461–472.
  • Cotner, R., J. M. Williams, L. T. Strom, and J. L. Strominger. 1983. The relationship between early T cell activation antigens and T cell proliferation, p. 63–68. In J. E. Hadden (ed.), Immunopharmacology: 2nd International Symposium. Pergamon Press, Inc., Elmsford, N.Y.
  • Davis, M. M., and P. J. Bjorkman. 1988. T-cell antigen receptor genes and T-cell recognition. Nature (London) 334:395–402.
  • Dignam, J. D., R. M. Lebovitz, and R. G. Roeder. 1983. Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei. Nucleic Acids Res. 11:1475–1489.
  • Dynan, W. S., and R. Tjian. 1983. The promoter-specific transcription factor Sp1 binds to upstream sequences in the SV40 early promoter. Cell 35:79–87.
  • Dynan, W. S., and R. Tjian. 1985. Control of eukaryotic messenger RNA synthesis by sequence-specific DNA-binding proteins. Nature (London) 316:774–778.
  • Gorman, C. M., L. F. Moffat, and B. H. Howard. 1982. Recombinant genomes which express chloramphenicol acetyltransferase in mammalian cells. Mol. Cell. Biol. 2:1044–1051.
  • Gottesdiener, K. M., B. A. Karpinski, T. Lindsten, J. L. Strominger, N. H. Jones, C. B. Thompson, and J. M. Leiden. 1988. Isolation and structural characterization of the human 4F2 heavy-chain gene, an inducible gene involved in T-lymphocyte activation. Mol. Cell. Biol. 8:3809–3819.
  • Greenberg, M. E., and E. B. Ziff. 1984. Stimulation of 3T3 cells induces transcription of the c-fos proto-oncogene. Nature (London) 311:433–438.
  • Haynes, B. F., M. E. Hemler, D. L. Mann, G. S. Eisenbarth, J. Shelhamer, H. S. Mostowski, C. A. Thomas, J. L. Strominger, and A. S. Fauci. 1981. Characterization of a monoclonal antibody (4F2) that binds to human monocytes and to a subset of activated lymphocytes. J. Immunol. 126:1409–1414.
  • Kelly, K., B. H. Cochran, C. D. Stiles, and P. Leder. 1983. Cell specific regulation of the c-myc gene by lymphocyte mitogens and platelet derived growth factor. Cell 35:603–610.
  • Kramer, W., and H.-J. Fritz. 1987. Oligonucleotide-directed construction of mutations via gapped duplex DNA. Methods Enzymol. 155:350–367.
  • Lamph, W. W., P. Wamsley, P. Sassone-Corsi, and I. M. Verma. 1988. Induction of proto-oncogene JUN/AP-1 by serum and TPA. Nature (London) 334:629–631.
  • Lee, W., P. Mitchell, and R. Tjian. 1987. Purified transcription factor AP-1 interacts with TPA-inducible enhancer elements. Cell 49:741–752.
  • Lenardo, M., J. W. Pierce, and D. Baltimore. 1987. Proteinbinding sites in Ig gene enhancers determine transcriptional activity and inducibility. Science 236:1573–1577.
  • Leung, K., and G. J. Nabel. 1988. HTLV-1 transactivator induces interleukin-2 receptor expression through an NF-κB-like factor. Nature (London) 333:776–778.
  • Lindsten, T., C. H. June, C. B. Thompson, and J. M. Leiden. 1988. Regulation of 4F2 heavy-chain gene expression during normal human T-cell activation can be mediated by multiple distinct molecular mechanisms. Mol. Cell. Biol. 8:3820–3826.
  • Maxam, A. M., and W. Gilbert. 1980. Sequencing end-labeled DNA with base-specific chemical cleavages. Methods Enzymol. 65:499–560.
  • McKnight, S., and R. Tjian. 1986. Transcriptional selectivity of viral genes in mammalian cells. Cell 46:795–805.
  • Mitchell, P. J., C. Wang, and R. Tjian. 1987. Positive and negative regulation of transcription in vitro: enhancer-binding protein AP-2 is inhibited by SV40 T antigen. Cell 50:847–861.
  • Parmacek, M. S., B. A. Karpinski, K. M. Gottesdiener, C. B. Thompson, and J. M. Leiden. 1989. Structure, expression, and regulation of the murine 4F2 heavy chain. Nucleic Acids Res. 17:1915–1931.
  • Peterson, C. L., and K. L. Calame. 1987. Complex protein binding within the mouse immunoglobulin heavy-chain enhancer. Mol. Cell. Biol. 7:4194–4203.
  • Prost, E., and D. D. Moore. 1986. CAT vectors for analysis of eukaryotic promoters and enhancers. Gene 45:107–111.
  • Ptashne, M.. 1988. How eukaryotic transcriptional activators work. Nature (London) 335:683–689.
  • Quackenbush, E., M. Clabby, K. M. Gottesdiener, J. Barbosa, N. H. Jones, J. L. Strominger, S. Speck, and J. M. Leiden. 1987. Molecular cloning of complementary DNAs encoding the heavy chain of the human 4F2 cell-surface antigen: a type II membrane glycoprotein involved in normal and neoplastic cell growth. Proc. Natl. Acad. Sci. USA 84:6526–6530.
  • Reed, J. C., J. D. Alpers, P. C. Nowell, and R. G. Hoover. 1986. Sequential expression of proto-oncogenes during lectin-stimu- lated mitogenesis of normal human lymphocytes. Proc. Natl. Acad. Sci. USA 83:3982–3986.
  • Robb, R. J., A. Munck, and K. A. Smith. 1981. T-cell growth factors: quantification, specificity, and biological relevance. J. Exp. Med. 154:1455–1474.
  • Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467.
  • Sassone-Corsi, P., W. W. Lamph, M. Kamps, and I. M. Verma. 1988. Associated cellular p39 is related to nuclear transcription factor AP-1. Cell 54:553–560.
  • Seldon, R. F., K. B. Howie, M. E. Rowe, H. M. Goodman, and D. D. Moore. 1986. Human growth hormone as a reporter gene in regulation studies employing transient gene expression. Mol. Cell. Biol. 6:3173–3179.
  • Singh, H., R. Sen, D. Baltimore, and P. A. Sharp. 1986. A nuclear factor that binds to a conserved sequence motif in transcriptional control elements of immunoglobulin genes. Nature (London) 319:154–158.
  • Teixeira, S., S. DiGrandi, and L. C. Kuhn. 1987. Primary structure of the human 4F2 antigen heavy chain predicts a transmembrane protein with a cytoplasmic NH2 terminus. J. Biol. Chem. 262:9574–9580.
  • Whitham, S. E., G. Murphy, P. Angel, H. J. Rahmsdorf, B. J. Smith, A. Lyons, T. J. R. Harris, J. J. Reynolds, P. Herrlich, and A. J. P. Docherty. 1986. Comparison of human stromelysin and collagenase by cloning and sequence analysis. Biochem. J. 240:913–916.

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