Notes: Transformation of NIH 3T3 Fibroblasts by an Activated Form of p59^hck

LITERATURE CITED

• Amrein, K. E., and B. M. Sefton. 1988. Mutation at a site of tyrosine phosphorylation in the lymphocyte-specific tyrosine kinase, p56lck, reveals its oncogenic potential in fibroblasts. Proc. Natl. Acad. Sci. USA 85:4247–4251.
   PubMed Web of Science ®Google Scholar
• Bishop, J. M.. 1985. Viral oncogenes. Cell 42:23–38.
   PubMed Web of Science ®Google Scholar
• Cartwright, C. A., W. Eckhart, S. Simon, and P. L. Kaplan. 1987. Cell transformation by pp60c-src mutated in the carboxyterminal regulatory domain. Cell 49:83–91.
   PubMed Web of Science ®Google Scholar
• Cooper, J. A., K. L. Gould, C. A. Cartwright, and T. Hunter. 1986. Tyr527 is phosphorylated in pp60c-src: implications for regulation. Science 231:1431–1434.
   PubMed Web of Science ®Google Scholar
• Cooper, J. A., and C. S. King. 1986. Dephosphorylation or antibody binding to the carboxy terminus stimulates pp60c-src. Mol. Cell. Biol. 6:4467–4477.
   PubMedGoogle Scholar
• Cooper, J. A., and A. MacCauley. 1988. Potential positive and negative autoregulation of p60c-src by intermolecular phosphorylation. Proc. Natl. Acad. Sci. USA 85:4232–4236.
   PubMed Web of Science ®Google Scholar
• Huhn, R. D., M. R. Posner, S. I. Rayter, J. G. Foulkes, and A. R. Frackleton, Jr.. 1987. Cell lines and peripheral blood leukocytes derived from individuals with chronic myelogenous leukemia display virtually identical proteins phosphorylated on tyrosine residues. Proc. Natl. Acad. Sci. USA 84:4408–4412.
   PubMed Web of Science ®Google Scholar
• Hunter, T., and J. A. Cooper. 1986. Protein-tyrosine kinases. Annu. Rev. Biochem. 54:897–930.
   Google Scholar
• Kamps, M. P., S. S. Taylor, and B. M. Sefton. 1984. Direct evidence that oncogenic tyrosine kinases and cyclic AMPdependent protein kinases have homologous ATP-binding sites. Nature (London) 310:589–592.
   PubMed Web of Science ®Google Scholar
• Kawakami, T., Y. Kawakami, S. A. Aaronson, and K. C. Robbins. 1988. Acquisition of transforming properties by FYN, a normal SRC-related human gene. Proc. Natl. Acad. Sci. USA 85:3870–3874.
   PubMed Web of Science ®Google Scholar
• Kmiecik, T. E., and D. Shalloway. 1987. Activation and suppression of pp60c-src transforming ability by mutation of its primary sites of tyrosine phosphorylation. Cell 49:65–73.
   PubMed Web of Science ®Google Scholar
• Mann, R., R. C. Mulligan, and D. Baltimore. 1983. Construction of a retrovirus packaging mutant and its use to produce helperfree defective retroviruses. Cell 33:153–159.
   PubMed Web of Science ®Google Scholar
• Marth, J. D., J. A. Cooper, C. S. King, S. F. Ziegler, D. A. Tinker, R. W. Overell, E. G. Krebs, and R. M. Perlmutter. 1988. Neoplastic transformation induced by an activated lymphocyte-specific protein tyrosine kinase (pp56lck). Mol. Cell. Biol. 8:540–550.
   PubMed Web of Science ®Google Scholar
• Perlmutter, R. M., J. D. Marth, S. F. Ziegler, A. M. Garvin, S. Pawar, M. P. Cooke, and K. M. Abraham. 1989. Specialized protein tyrosine kinase proto-oncogenes in hematopoietic cells. Biochim. Biophys. Acta 948:245–262.
   PubMedGoogle Scholar
• Piwnica-Worms, H., K. B. Saunders, T. M. Roberts, A. E. Smith, and S. H. Cheng. 1987. Tyrosine phosphorylation regulates the biochemical and biological properties of pp60c-src. Cell 49:75–82.
   PubMed Web of Science ®Google Scholar
• Quintrell, N., R. Lebo, H. Varmus, J. M. Bishop, M. J. Pettenati, M. M. Le Beau, M. O. Diaz, and J. D. Rowley. 1987. Identification of a human gene (HCK) that encodes a proteintyrosine kinase and is expressed in hemopoietic cells. Mol. Cell. Biol. 7:2267–2275.
   PubMed Web of Science ®Google Scholar
• Reynolds, A. B., J. Vila, T. J. Lansing, W. M. Potts, M. J. Wilber, and J. T. Parsons. 1987. Activation of the oncogenic potential of the avian cellular src protein by specific structural alteration of the carboxy terminus. EMBO J. 6:2359–2364.
   PubMed Web of Science ®Google Scholar
• Scher, C. D., and R. Siegler. 1975. Direct transformation of 3T3 cells by Abelson murine leukemic virus. Nature (London) 253:729–731.
   PubMed Web of Science ®Google Scholar
• Stahl, M. L., C. R. Ferenz, K. L. Kelleher, R. W. Kriz, and J. L. Knopf. 1988. Sequence similarity of phospholipase C with the non-catalytic region of src. Nature (London) 332:269–272.
   PubMed Web of Science ®Google Scholar
• Testa, J. R., A. Kinnealey, J. D. Rowley, D. W. Golde, and D. Potter. 1978. Deletion of the long arm of chromosome 20 [del (20) (q11)] in myeloid disorders. Blood 52:868–877.
   PubMed Web of Science ®Google Scholar
• Ziegler, S. F., J. D. Marth, D. B. Lewis, and R. M. Perlmutter. 1987. Novel protein-tyrosine kinase (hck) preferentially expressed in cells of hematopoietic origin. Mol. Cell. Biol. 7:2276–2285.
   PubMedGoogle Scholar
• Ziegler, S. F., C. B. Wilson, and R. M. Perlmutter. 1988. Augmented expression of a myeloid-specific protein tyrosine kinase gene (hck) after macrophage activation. J. Exp. Med. 168:1801–1810.
   PubMed Web of Science ®Google Scholar