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Cell Growth and Development

A Transfected L-myc Gene Can Substitute for c-myc in Blocking Murine Erythroleukemia Differentiation

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Pages 2734-2737 | Received 16 Nov 1988, Accepted 27 Feb 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Birrer, M. J., S. Segal, J. S. DeGreve, F. Kaye, E. A. Sausville, and J. D. Minna. 1988. L-myc cooperates with ras to transform primary rat embryo fibroblasts. Mol. Cell. Biol. 8:2668–2673.
  • Campisi, J., H. Gray, A. Pardee, M. Dean, and G. Sonenshein. 1984. Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation. Cell 36:241–247.
  • Chirgwin, J. M., A. E. Prybyla, R. J. MacDonald, and W. J. Rutter. 1974. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. J. Biochem. 18:5294–5299.
  • Clarke, M. F., J. F. Kukowska-Latallo, E. Westin, M. Smith, and E. V. Prochownik. 1988. Constitutive expression of a c-myb cDNA blocks Friend murine erythroleukemic cell differentiation. Mol. Cell. Biol. 8:884–892.
  • Coppola, J. A., and M. D. Cole. 1986. Constitutive c-myc oncogene expression blocks mouse erythroleukemia cell differentiation but not commitment. Nature (London) 320:760–763.
  • Dephino, R. A., K. S. Hatton, A. Tesfaye, G. D. Yancopoulus, and F. W. Alt. 1987. The human myc gene family: structure and activity of L-myc and a L-myc pseudogene. Genes Dev. 1:1311–1326.
  • Dmitrovsky, E., W. M. Kuehl, G. Hollis, I. R. Kirsch, T. P. Bender, and S. Segal. 1986. Expression of a transfected human c-myc oncogene inhibits differentiation of a mouse erythroleukemia cell line. Nature (London) 322:748–750.
  • Friend, C., W. Scher, J. G. Holland, and T. Sato. 1971. Hemoglobin synthesis in murine virus-induced leukemic cell in vitro: stimulation of erythroid differentiation by dimethyl sulfoxide. Proc. Natl. Acad. Sci. USA 68:378–382.
  • Graham, F. L., and A. J. Van der Eb. 1973. A new technique for the assay of infectivity of human adenovirus DNA. Virology 52:456–467.
  • Kaye, F., J. Battey, M. Nau, B. Brooks, E. Seifter, J. De Greve, M. Birrer, E. Sausville, and J. Minna. 1988. Structure and expression of the human L-myc gene reveal a complex pattern of alternative mRNA processing. Mol. Cell. Biol. 8:186–195.
  • Keath, E. J., P. G. Caimi, and M. D. Cole. 1984. Fibroblast lines expressing activated c-myc oncogene are tumorigenic in nude mice and syngenic animals. Cell 39:339–348.
  • Kelekar, A., and M. D. Cole. 1986. Tumorigenicity of fibroblast lines expressing the adenovirus Ela, cellular P53, or normal c-myc genes. Mol. Cell. Biol. 6:7–14.
  • Kirsch, I. R., V. Bertness, J. Silver, and G. F. Hollis. 1986. Regulated expression of the c-myb and c-myc oncogenes during erythroid differentiation. J. Cell. Biochem. 32:11–21.
  • Kuehl, W. M., T. P. Bender, J. Stafford, D. McClinton, S. Segal, and E. Dmitrovsky. 1989. Expression and function of the c-myb oncogene during hematopoietic differentiation. Curr. Top. Microbiol. Immun. 141:318–323.
  • Kume, T. U., S. Takada, and M. Obinata. 1988. Probability that the commitment of murine erythroleukemia cells differentiation is determined by the c-myc level. J. Mol. Biol. 202:779–786.
  • Lachman, H. M., G. Cheng, and A. I. Skoultchi. 1984. Expression of c-myc changes during differentiation of mouse eryth- roylekemia cells. Nature (London) 310:592–594.
  • Lehrach, H., D. Diamond, J. Wozney, and H. Boedtker. 1977. RNA molecular weight determination by gel electrophoresis under denaturing conditions, a critical reexamination. Biochemistry 16:4743–4751.
  • Marks, P. A., and R. A. Rifkind. 1978. Erythroleukemic differentiation. Annu. Rev. Biochem. 47:419–448.
  • Prochownik, E. V., and J. Kukowska. 1986. Deregulated expression of c-myc by murine erythroleukemia cells prevents differentiation. Nature (London) 322:848–850.
  • Rigby, P. W. J., M. Dieckmann, C. Rhodes, and P. Berg. 1977. Labeling of DNA to high specific activity in vitro by nick translation with DNA polymerase one. J. Mol. Biol. 113:237–251.
  • Sarid, J., T. D. Malazonetis, W. Murphy, and P. Leder. 1987. Evolutionary conserved regions of the human c-myc protein can be uncoupled from transforming activity. Proc. Natl. Acad. Sci. USA 84:170–173.
  • Segal, S., E. Dmitrovsky, and M. P. de la Cedena. 1988. The effect of a transfected c-myc proto-oncogene on cellular differentiation. Mol. Immunol. 25:1129–1132.
  • Stone, J., T. DeLange, G. Ramsay, E. Jakobovits, J. M. Bishop, H. Varmus, and W. Lee. 1987. Definition of regions in human c-mvc involved in transformation and nuclear localization. Mol. Cell. Biol. 7:1697–1709.
  • Westin, E. H., R. C. Gallo, S. K. Arya, A. Eva, L. M. Souza, M. A. Baluda, S. A. Aaronson, and F. Wong-Staal. 1982. Differential expression of the AMV gene in human hematopoietic cells. Proc. Natl. Acad. Sci. USA 79:2194–2198.
  • Wingrove, T. G., R. Watt, P. King, and I. G. Macara. 1988. Stabilization of myc proto-oncogene proteins during Friend murine erythroleukemia cell differentiation. J. Biol. Chem. 263:8918–8924.

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