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Cell Growth and Development

Insulin and Insulinlike Growth Factor 1 (IGF-1) Receptors during Central Nervous System Development: Expression of Two Immunologically Distinct IGF-1 Receptor β Subunits

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Pages 2806-2817 | Received 27 Jan 1989, Accepted 28 Mar 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Berry, M.. 1974. Development of the cerebral neocortex of the rat, p. 7–67. In G. Gottlieb (ed.), Studies on the development of behavior and the nervous system, vol. 2. Academic Press, Inc., New York.
  • Burnette, W. N.. 1981. “Western blotting”: electrophoretic transfer of proteins from sodium dodecyl sulfate-polyacryl- amide gels to unmodified nitrocellulose and radiographic detection with antibody and radioiodinated protein A. Anal. Biochem. 112:195–203.
  • Chou, C. K., T. J. Dull, D. S. Russell, R. Gherzi, D. Lebwohl, A. Ullrich, and O. M. Rosen. 1987. Human insulin receptors mutated at the ATP-binding site lack protein tyrosine kinase activity and fail to mediate postreceptor effects of insulin. J. Biol. Chem. 262:1842–1847.
  • Crettaz, M.. 1988. Hepatoma cells in culture as a tool for the study of insulin receptor and insulin action, p. 221–233. In C. R. Kahn, and L. C. Harrison (ed.), Insulin receptors, part A. Methods for the study of structure and function. Alan R. Liss, New York.
  • Ebina, Y., E. Araki, M. Taira, F. Shimada, M. Mori, C. S. Craik, K. Siddle, S. B. Pierce, R. A. Roth, and W. J. Rutter. 1987. Replacement of lysine residue 1030 in the putative ATP- binding region of the insulin receptor abolishes insulin- and antibody-stimulated glucose uptake and receptor kinase activity. Proc. Natl. Acad. Sci. USA 84:704–708.
  • Ebina, Y., L. Ellis, K. Jamagin, M. Edery, L. Graf, E. Clauser, J. Ou, F. Masiarz, Y. W. Kan, I. D. Goldfine, R. A. Roth, and W. J. Rutter. 1985. The human insulin receptor cDNA: the structural basis for hormone-activated transmembrane signalling. Cell 40:747–758.
  • Ellis, L., E. Clauser, D. O. Morgan, M. Edery, R. A. Roth, and W. J. Rutter. 1986. Replacement of insulin receptor tyrosine residues 1162 and 1163 compromises insulin-stimulated kinase activity and uptake of 2-deoxyglucose. Cell 45:721–732.
  • Fernandex-Almonacid, R., and O. M. Rosen. 1987. Structure and ligand specificity of the Drosophila melanogaster insulin receptor. Mol. Cell. Biol. 7:2718–2727.
  • Gammeltoft, S., G. K. Haselbacher, R. E. Humbel, M. Fehlmann, and E. Van Obberghen. 1985. Two types of receptor for insulin-like growth factors in mammalian brain. EMBO J. 4:3407–3412.
  • Garofalo, R. S., and O. M. Rosen. 1988. Tissue localization of Drosophila melanogaster insulin receptor transcripts during development. Mol. Cell. Biol. 8:1638–1647.
  • Havrankova, J., J. Roth, and M. Brownstem. 1978. Insulin receptors are widely distributed in the central nervous system of the rat. Nature (London) 272:827–829.
  • Hedo, J. A., L. C. Harrison, and J. Roth. 1981. Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors. Biochemistry 20:3385–3393.
  • Hendricks, S. A., F. De Pablo, and J. Roth. 1984. Early development and tissue-specific patterns of insulin binding in chick embryo. Endocrinology 115:1315–1323.
  • Herrera, R., L. Petruzzelli, N. Thomas, H. N. Bramson, E. T. Kaiser, and O. M. Rosen. 1985. An antipeptide antibody that specifically inhibits insulin receptor autophosphorylation and protein kinase activity. Proc. Natl. Acad. Sci. USA 82:7899–7903.
  • Herrera, R., L. M. Petruzzelli, and O. M. Rosen. 1986. Antibodies to deduced sequences of the insulin receptor distinguish conserved and nonconserved regions in the IGF-I receptor. J. Biol. Chem. 261:2489–2491.
  • Herrera, R., and O. M. Rosen. 1986. Autophosphorylation of the insulin receptor in vitro. J. Biol. Chem. 261:11980–11985.
  • Herrera, R., and O. M. Rosen. 1988. Use of antipeptide antibodies to probe functional domains of the beta subunit of the human insulin receptor, p. 181–188. In C. R. Kahn, and L. C. Harrison (ed.), Insulin receptors, part A. Methods for the study of structure and function. Alan R. Liss, New York.
  • Jacobs, S., and P. Cuatrecasas. 1986. Phosphorylation of receptors for insulin and insulin-like growth factor I: effects of hormones and phorbol esters. J. Biol. Chem. 261:934–939.
  • Jacobs, S., F. C. Kull, Jr., H. S. Earp, M. E. Svoboda, J. J. Van Wyk, and P. Cuatrecasas. 1983. Somatomedin-C stimulates the phosphorylation of the beta subunit of its own receptor. J. Biol. Chem. 258:9581–9584.
  • Jacobson, M.. 1978. Developmental neurobiology. Plenum Publishing Corp., New York.
  • Jonas, H. A., and L. C. Harrison. 1985. The human placenta contains two distinct binding and immunoreactive species of insulin-like growth factor-I receptors. J. Biol. Chem. 260:2288–2294.
  • Kadowaki, T., S. Koyasu, E. Nishida, K. Tobe, T. Izumi, F. Takaku, H. Sakai, I. Yahara, and M. Kasuga. 1987. Tyrosine phosphorylation of common and specific sets of cellular proteins rapidly induced by insulin, insulin-like growth factor I, and epidermal growth factor in an intact cell. J. Biol. Chem. 262:7342–7350.
  • Kappy, M. S., and M. K. Raizada. 1982. Adult-level insulin binding is present in term fetal rat CNS membranes. Brain Res. 249:390–392.
  • Kappy, M. S., S. Sellinger, and M. Raizada. 1984. Insulin binding in four regions of the developing rat brain. J. Neurochem. 42:198–203.
  • Kull, F. C., Jr., S. Jacobs, Y.-F. Su, M. E. Svoboda, J. J. Van Wyk, and P. Cuatrecasas. 1983. Monoclonal antibodies to receptors for insulin and somatomedin-C. J. Biol. Chem. 258:6561–6566.
  • Laenunli, U. K.. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680–685.
  • Lowe, W. L., Jr., F. T. Boyd, D. W. Clarke, M. K. Raizada, C. Hart, and D. Leroith. 1986. Development of brain insulin receptors: structural and functional studies of insulin receptors from whole brain and primary cell cultures. Endocrinology 119:25–35.
  • Lowe, W. L., Jr., and D. LeRoith. 1986. Insulin receptors from guinea pig liver and brain: structural and functional studies. Endocrinology 118:1669–1677.
  • Lowe, W. L., Jr., and D. LeRoith. 1986. Tyrosine kinase activity of brain insulin and IGF-I receptors. Biochem. Biophys. Res. Commun. 134:532–538.
  • Massague, J., L. A. Blinderman, and M. P. Czech. 1982. The high affinity insulin receptor mediates growth stimulation in rat hepatoma cells. J. Biol. Chem. 257:13958–13963.
  • McClain, D. A., H. Maegawa, J. Lee, T. J. Dull, A. Ullrich, and J. M. Olefsky. 1987. A mutant insulin receptor with defective tyrosine kinase displays no biologic activity and does not undergo endocytosis. J. Biol. Chem. 262:14663–14671.
  • Morgan, D. O., K. Jarnagin, and R. A. Roth. 1986. Purification and characterization of the receptor for insulin-like growth factor I. Biochemistry 25:5560–5564.
  • Morgan, D. O., and R. A. Roth. 1987. Acute insulin action requires insulin receptor kinase activity: introduction of an inhibitory monoclonal antibody into mammalian cells blocks the rapid effects of insulin. Proc. Natl. Acad. Sci. USA 84:41–45.
  • Ocrant, I., K. L. Valentino, L. F. Eng, R. L. Hintz, D. M. Wilson, and R. G. Rosenfeld. 1988. Structural and immunohistochemical characterization of insulin-like growth factor I and II receptors in the murine central nervous system. Endocrinology 123:1023–1034.
  • Ota, A., G. L. Wilson, and D. LeRoith. 1988. Insulin-like growth factor I receptors on mouse neuroblastoma cells: two beta subunits are derived from differences in glycosylation. Eur. J. Biochem. 174:521–530.
  • Pacold, S. T., and W. G. Blackard. 1979. Central nervous system insulin receptors in normal and diabetic rats. Endocrinology 105:1452–1457.
  • Petruzzelli, L., R. Herrera, R. Arenas-Garcia, R. Fernandez, M. J. Birnbaum, and O. M. Rosen. 1986. Isolation of a Drosophila genomic sequence homologous to the kinase domain of the human insulin receptor and detection of the phosphorylated Drosophila receptor with an anti-peptide antibody. Proc. Natl. Acad. Sci. USA 83:4710–4714.
  • Pomerance, M., J.-M. Gavaret, C. Jacquemin, C. Matricon, D. Toru-Delbauffe, and M. Pierre. 1988. Insulin and insulin-like growth factor I receptors during postnatal development of rat brain. Dev. Brain Res. 42:77–83.
  • Recio-Pinto, E., and D. N. Ishii. 1984. Effects of insulin, insulinlike growth factor II, and nerve growth factor on neurite outgrowth in cultured human neuroblastoma cells. Brain Res. 302:323–334.
  • Recio-Pinto, E., M. M. Rechler, and D. N. Ishii. 1986. Effects of insulin, insulin-like growth factor II, and nerve growth factor on neurite formation and survival in cultured sympathetic and sensory neurons. J. Neurosci. 6:1211–1219.
  • Rees-Jones, R. W., S. A. Hendricks, M. Quarum, and J. Roth. 1984. The insulin receptor of rat brain is coupled to tyrosine kinase activity. J. Biol. Chem. 259:3470–3474.
  • Rosen, O. M.. 1987. After insulin binds. Science 237:1452–1458.
  • Roth, R. A., D. O. Morgan, J. Beaudoin, and V. Sara. 1986. Purification and characterization of the human brain insulin receptor. J. Biol. Chem. 261:3753–3757.
  • Russell, D. S., R. Gherzi, E. L. Johnson, C.-K. Chou, and O. M. Rosen. 1987. The protein-tyrosine kinase activity of the insulin receptor is necessary for insulin-mediated receptor down-regulation. J. Biol. Chem. 262:11833–11840.
  • Sara, V. R., K. Hall, M. Misaki, L. Fryklund, N. Christensen, and L. Wetterberg. 1983. Ontogenesis of somatomedin and insulin receptors in the human fetus. J. Clin. Invest. 71:1084–1094.
  • Shemer, J., M. Adamo, G. L. Wilson, D. Heffez, Y. Zick, and D. LeRoith. 1987. Insulin and insulin-like growth factor-I stimulate a common endogenous phosphoprotein substrate (ppl85) in intact neuroblastoma cells. J. Biol. Chem. 262:15476–15482.
  • Shemer, J., M. K. Raizada, B. A. Masters, A. Ota, and D. LeRoith. 1987. Insulin-like growth factor I receptors in neuronal and glial cells: characterization and biological effects in primary culture. J. Biol. Chem. 262:7693–7699.
  • Stadtmauer, L., and O. M. Rosen. 1986. Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo. J. Biol. Chem. 261:10000–10005.
  • Steele-Perkins, G., J. Turner, J. C. Edman, J. Hari, S. B. Pierce, C. Stover, W. J. Rutter, and R. A. Roth. 1988. Expression and characterization of a functional human insulin-like growth factor I receptor. J. Biol. Chem. 263:11486–11492.
  • Takayama, S., M. F. White, V. Lauris, and C. R. Kahn. 1984. Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells. Proc. Natl. Acad. Sci. USA 81:7797–7801.
  • Toran-Allerand, C. D., L. Ellis, and K. H. Pfenninger. 1988. Estrogen and insulin synergism in neurite growth enhancement in vitro: mediation of steroid effects by interactions with growth factors? Dev. Brain Res. 41:87–100.
  • Ullrich, A., J. R. Bell, E. Y. Chen, R. Herrera, L. M. Petruzzelli, T. J. Dull, A. Gray, L. Coussens, Y.-C. Liao, M. Tsubokawa, A. Mason, P. H. Seeburg, C. Grunfeld, O. M. Rosen, and J. Ramachandran. 1985. Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes. Nature (London) 313:756–761.
  • Ullrich, A., A. Gray, A. W. Tam, T. Yang-Feng, M. Tsubokawa, C. Collins, W. Henzel, T. LeBon, S. Kathuria, E. Chen, S. Jacobs, U. Francke, J. Ramachandran, and Y. Fujita-Yamaguchi. 1986. Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity. EMBO J. 5:2503–2512.
  • Wallis, L., L. Ellis, K. Suh, and K. H. Pfenninger. 1985. Immunolocalization of a neuronal growth-dependent membrane glycoprotein. J. Cell Biol. 101:1990–1998.
  • Yu, K.-T., M. A. Peters, and M. P. Czech. 1986. Similar control mechanisms regulate the insulin and type I insulin-like growth factor receptor kinases. J. Biol. Chem. 261:11341–11349.

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