12
Views
11
CrossRef citations to date
0
Altmetric
Cell Growth and Development

Molecular Cloning, Sequence Analysis, and Functional Expression of a Novel Growth Regulator, Oncostatin M

, , , , , , , , , , & show all
Pages 2847-2853 | Received 24 Feb 1989, Accepted 07 Apr 1989, Published online: 31 Mar 2023

LITERATURE CITED

  • Angel, P., M. Imagawa, R. Chiu, B. Stein, R. J. Imbra, H. J. Rahmsdorf, C. Jonat, P. Herrlich, and M. Karin. 1987. Phorbol ester inducible genes contain a common CIS element recognized by a TPA-modulated trans-acting factor. Cell 49:729–739.
  • Aruffo, A., and B. Seed. 1987. Molecular cloning of a CD28 cDNA by a high-efficiency COS cell expression system. Proc. Natl. Acad. Sci. USA 84:8573–8577.
  • Aviv, H., and P. Leder. 1972. Purification of biologically active globin messenger RNA by chromatography on oligothymidylic acid-cellulose. Proc. Natl. Acad. Sci. USA 69:1408–1412.
  • Brewer, G., and J. Ross. 1988. Poly(A) shortening and degradation of the 3′ A+U-rich sequences of human c-myc mRNA in a cell-free system. Mol. Cell. Biol. 8:1697–1708.
  • Brown, T. J., M. N. Lioubin, and H. Marquardt. 1987. Purification and characterization of cytostatic lymphokines produced by activated human T lymphocytes. J. Immunol. 139:2977–2983.
  • Caput, D., B. Buetler, K. K. Hartog, R. Thayer, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83:1670–1674.
  • Chen, L., Y. Mory, A. Zilberstein, and M. Revel. 1988. Growth inhibition of human breast carcinoma and leukemia/lymphoma cell lines by recombinant interferon-β2. Proc. Natl. Acad. Sci. USA 85:8037–8041.
  • Chirgwin, J. M., A. E. Przbyla, R. J. MacDonald, and W. J. Rutter. 1979. Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease. Biochemistry 18:5294–5299.
  • Cush, J. J., and P. E. Lipsky. 1987. The immunopathogenesis of rheumatoid arthritis: the role of cytokines in chronic inflammation. Clin. Aspects Autoimmun. 1:2–13.
  • Dedhar, S., L. Gaboury, P. Galloway, and C. Eaves. 1988. Human granulocyte-macrophage colony stimulating factor is a growth factor on a variety of cell types of nonhemopoietic origin. Proc. Natl. Acad. Sci. USA 85:9253–9257.
  • Dente, L., G. Cesareni, and R. Cortese. 1983. pEMBL: a new family of single stranded plasmids. Nucleic Acids Res. 25:1645–1655.
  • Derynck, R., J. A. Jarrett, E. Y. Chen, D. H. Eaton, J. R. Bell, R. K. Assoiian, A. B. Roberts, M. B. Sporn, and D. V. Goeddel. 1985. Human transforming growth factor-β complementary DNA sequence and expression in normal and transformed cells. Nature (London) 316:701–705.
  • Dinarello, C. A., and J. W. Mier. 1987. Lymphokines. N. Engl. J. Med. 317:940–945.
  • Gentry, L. E., N. R. Webb, G. J. Lim, A. M. Brunner, J. E. Ranchalis, D. R. Twardzik, M. N. Lioubin, H. Marquardt, and A. F. Purchio. 1987. Type 1 transforming growth factor-β: amplified expression and secretion of mature and precursor polypeptides in Chinese hamster ovary cells. Mol. Cell. Biol. 7:3418–3427.
  • Ghizman, Y.. 1981. SV40-transformed simian cells support the replication of early SV40 mutants. Cell 23:175–182.
  • Henikoff, S.. 1984. Unidirectional digestion with exonuclease III creates targeted breakpoints for DNA sequencing. Gene 28:351–359.
  • Kozak, M.. 1987. An analysis of 5′-noncoding sequences from 699 vertebrate messenger RNAs. Nucleic Acids Res. 15:8125–8148.
  • Kyte, J., and R. F. Doolittle. 1982. A simple method for displaying the hydrophobic character of a protein. J. Mol. Biol. 157:105–132.
  • Lathe, R.. 1985. Synthetic oligonucleotide probes deduced from amino acid sequence data: theoretical and practical considerations. J. Mol. Biol. 183:1–12.
  • Leary, J. L., D. J. Brigati, and D. C. Ward. 1983. Rapid and sensitive colorimetric method for visualizing biotin-labeled DNA probes hybridized to DNA or RNA immobilized to nitrocellulose. Proc. Natl. Acad. Sci. USA 80:4045–4049.
  • Linsley, P. S., M. Bolton-Hansen, D. Horn, N. Malik, J. C. Kallestad, V. Ochs, J. M. Zarling, and M. Shoyab. 1989. Identification and characterization of cellular receptors for the growth regulator, oncostatin M. J. Biol. Chem. 264:4282–4289.
  • Linsley, P. S., D. Horn, H. Marquardt, J. P. Brown, I. Hellstrom, K. E. Hellstrom, V. Ochs, and E. Tolentino. 1986. Identification of a novel serum protein secreted by lung carcinoma cells. Biochemistry 25:2978–2986.
  • Maniatis, T., E. F. Fritsch, and J. Sambrook. 1982. Molecular cloning: a laboratory manual. Cold Spring Harbor Laboratory, Cold Spring Harbor, N.Y.
  • Marquardt, H., G. J. Todaro, L. E. Henderson, and S. Orozlan. 1981. Purification and primary structure of a polypeptide with multiplication stimulatory activity from rat liver cell cultures. J. Biol. Chem. 256:6859–6865.
  • Nathan, C. F.. 1987. Secretory products of macrophages. J. Clin. Invest. 79:319–326.
  • Nilsson, G., J. G. Belasco, and S. N. Cohen. 1984. Growth-rate dependent regulation of mRNA stability in Escherichia coli. Nature (London) 312:75–77.
  • Reeves, R., T. S. Elton, M. S. Nissen, D. Lehn, and K. R. Johnson. 1987. Postranscriptional gene regulation and specific binding of the nonhistone protein HMG-I by the 3′-untranslated region of bovine interleukin 2 cDNA. Proc. Natl. Acad. Sci. USA 84:6531–6535.
  • Reeves, R., A. G. Spies, M. S. Nissen, C. D. Buck, A. D. Weinberg, P. J. Barr, N. S. Magnuson, and J. A. Magnuson. 1986. Molecular cloning of a functional bovine interleukin 2 cDNA. Proc. Natl. Acad. Sci. USA 83:3228–3232.
  • Rigby, P. W. J., M. Dieckmann, C. Rhodes, and P. Berg. 1977. Labeling deoxyribonucleic acid to high specific activity in vitro by nick translation with DNA polymerase I. J. Mol. Biol. 113:237–254.
  • Rose, T. M., G. D. Plowman, D. B. Teplow, W. T. Dreyer, K. E. Hellstrom, and J. P. Brown. 1986. Primary structure of the human melanoma-associated antigen p97 (melanotransferrin) deduced from the mRNA sequence. Proc. Natl. Acad. Sci. USA 83:1261–1265.
  • Sanger, F., S. Nicklen, and A. R. Coulson. 1977. DNA sequencing with chain-terminating inhibitors. Proc. Natl. Acad. Sci. USA 74:5463–5467.
  • Schmidt, J. A., S. B. Mizel, D. Cohen, and I. Green. 1982. Interleukin-1, a potent regulator of fibroblast regulation. J. Immunol. 128:2177–2182.
  • Schrader, J. W., H. J. Ziltner, and K. B. Leslie. 1986. Structural homologies among the hematopoietins. Proc. Natl. Acad. Sci. USA 83:2458–2462.
  • Schuler, G. D., and M. D. Cole. 1989. GM-CSF mRNA stabilities are independently regulated in trans in a mouse monocytic tumor. Cell 55:1115–1122.
  • Sharpies, K., G. D. Plowman, T. M. Rose, D. R. Twardzik, and A. F. Purchio. 1987. Cloning and sequence analysis of simian transforming growth factor-β cDNA. DNA 6:239–244.
  • Shaw, G., and R. Kamen. 1986. A conserved AU sequence from the 3′-untranslated region of GM-CSF mRNA mediates selective mRNA degradation. Cell 46:659–667.
  • Sugarman, B. J., B. B. Aggarwal, P. E. Hass, I. S. Figari, M. A. Palladino, Jr., and H. M. Shepard. 1985. Recombinant human tumor necrosis factor-alpha: effects on proliferation of normal and transformed cells in vitro. Science 230:943–945.
  • Sussman, D. J., and G. Milman. 1984. Short-term, high-efficiency expression of transfected DNA. Mol. Cell. Biol. 4:1641–1643.
  • Wilson, T., and R. Treisman. 1988. Removal of poly(A) and consequent degradation of c-fos mRNA facilitated by 3′ AUrich sequences. Nature (London) 336:396–399.
  • Wong, G. G., J. S. Witek, P. A. Temple, K. M. Wilkens, A. C. Leary, D. P. Luxenberg, S. S. Jones, E. L. Brown, R. M. Kay, E. C. Orr, C. Shoemaker, D. W. Golde, R. J. Kaufman, R. M. Keick, E. A. Wang, and S. C. Clark. 1985. Human GM-CSF: molecular cloning of the complementary DNA and purification of the natural and recombinant proteins. Science 228:810–815.
  • Zarling, J. M., M. Shoyab, H. Marquardt, M. B. Hanson, M. N. Lioubin, and G. L. Todaro. 1986. Oncostatin M: a growth regulator produced by differentiated histiocytic lymphoma cells. Proc. Natl. Acad. Sci. USA 83:9739–9743.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.