Porcine chromaffin cells, culture, and transplant for antinociceptive effects in rodents and primates

REFERENCES

• Sagen J, Pappas GD. Morphological and functional correlates of chromaffin cell transplants in CNS pain modulatory regions. Ann N Y Acad Sci 1987; 495: 306–333
   PubMed Web of Science ®Google Scholar
• Yeomans DC, Lu Y, Laurito C, et al. Antinociceptive effects of chromaffin cell xenografts in non-human primates. SFN abstract #822.15,2000
   Google Scholar
• Winnie AP, Pappas GD, Das Gupta TK, et al. Subarachnoid adrenal medullary transplants for terminal cancer pain. A report of preliminary studies. Anesthesiology 1993; 79: 644–653
   PubMed Web of Science ®Google Scholar
• Pappas GD, Lazorthes Y, Bes JC, et al. Relief of intractable cancer pain by human chromaffin cell transplants: Experience at two medical centers. Neurol Res 1997; 19: 71–77
   PubMed Web of Science ®Google Scholar
• Bes JC, Tkaczuk J, Czech KA, et al. One-year chromaffin cell al lograft survival in cancer patients with chronic pain: Morphological and functional evidence. Cell Transplant 1998; 7: 227–238
   PubMed Web of Science ®Google Scholar
• Lazorthes Y, Bes JC, Sagen J, et al. Transplantation of human chromaffin cells for control of intractable cancer pain. Acta Neurochir Suppl (Wien) 1995; 64: 97–100
   Google Scholar
• Lazorthes Y, Sagen J, Sallerin B, et a/. Human chromaffin cell graft into the CSF for cancer pain management: A prospective phase It clinical study. Pain 2000; 87: 19–32
   PubMed Web of Science ®Google Scholar
• Sol JC, Sallerin B, Larrue S, et al. Intrathecal xenogeneic chromaffin cell grafts reduce nociceptive behavior in a rodent tonic pain model. Exper Neurol 2004; 186: 198–211
   PubMed Web of Science ®Google Scholar
• Unsicker K. The trophic cocktail made by adrenal chromaffin cells. Exp Neurol 1993; 123: 167–173
   PubMed Web of Science ®Google Scholar
• Livett BG, Dean DM, Whelan LG, etal. Co-release of enkephalin and catecholamines from cultured adrenal chromaffin cells. Nature 1981; 289: 317–319
   PubMed Web of Science ®Google Scholar
• Wilson SP, Chang KJ, Viveros OH. Proportional secretion of opioid peptides and catecholamines from adrenal chromaffin cells in culture. J Neurosci 1982; 2: 1150–1156
   PubMed Web of Science ®Google Scholar
• Sagen J, Pappas GD, Perlow MJ. Adrenal medullary tissue transplants in the rat spinal cord reduce pain sensitivity. Brain Res 1986; 384: 189–194
   PubMed Web of Science ®Google Scholar
• Sagen J, Pappas GD, Pollard HB. Analgesia induced by isolated bovine chromaffin cells implanted in rat spinal cord. Proc Natl Acad Sci USA 1986; 83: 7522–7526
   PubMed Web of Science ®Google Scholar
• Sagen J, Kemmler JE, Wang H. Adrenal medullary transplants increase spinal cord cerebrospinal fluid catecholamine levels and reduce pain sensitivity. Neurochem 1991; 56: 623–627
   PubMed Web of Science ®Google Scholar
• Hama A, Sagen J. Alleviation of neuropathic pain symptoms by xenogeneic chromaffin cell grafts in the spinal subarachnoid space. Brain Res 1994; 651: 183–193
   PubMed Web of Science ®Google Scholar
• Yu W, Hao JX, Xu Xi, et a/. Immunoisolating encapsulation of intrathecally implanted bovine chromaffin cells prolongs their survival and produces anti-allodynic effect in spinally injured rats. Eur J Pain 1998; 2: 143–151
   PubMed Web of Science ®Google Scholar
• Yeomans DC, Pirec V, Proudfit HK. Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Behavioral evidence. Pain 1996; 68: 133–140
   PubMed Web of Science ®Google Scholar
• Yeomans DC, Proudfit HK. Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Electrophysiological evidence. Pain 1996; 68: 141–150
   PubMed Web of Science ®Google Scholar
• Onishi A, Iwamoto M, Akita T, et a/. Pig cloning by microinjection of fetal fibroblast nuclei. Science 2000; 289: 1188–1190
   PubMed Web of Science ®Google Scholar
• Michalewicz P, Laurito CE, Pappas GD, et al. Purification of adrenal chromaffin cells increases antinociceptive efficacy of xenotransplants without immunosuppression. Cell Transplant 1999; 8: 103–109
   PubMed Web of Science ®Google Scholar
• Elcin A, Elcin YM, Pappas GD. Neural tissue engineering: Adrenal chromaffin cell attachment and viability on chitosan scaffolds. Neurol Res 1998; 20: 648–654
   PubMed Web of Science ®Google Scholar
• Elcin YM, Elcin AE, Pappas GD. Functional and morphological characteristics of bovine adrenal chromaffin cells on macroporous poly(D,L-lactide-co-glycolide) scaffolds. Tissue Eng 2003; 9: 1047–1056
   PubMedGoogle Scholar
• Sagen J, Ortega JD. Influence of the CNS environment on chromaffin cell survival and catecholamine secretion patterns. J Neurochem 1994; 63: 1159–1162
   PubMed Web of Science ®Google Scholar
• Czech KA, Pollak R, Pappas GD, et a/. Bovine chromaffin cells for CNS transplantation do not elicit xenogeneic T cell proliferative responses in vitro. Cell Transplant. 1996; 5: 257–267
   Google Scholar
• Czech KA, Ryan JW, Sagen J, et a/. The influence of xenotransplant immunogenicity and immunosuppression on host MHC expression in the rat CNS. Exp Neurol 1997; 147: 66–83
   PubMed Web of Science ®Google Scholar
• Pappas GD. Fine structure of host-graft relationships between transplanted chromaffin cells and CNS. FASEB J1999; 13 (Supple. 2): 5277—S280
   Google Scholar
• Nagashima H, Fujimura T, Takahagi Y, et a/. Development of efficient strategies for the production of genetically modified pigs (review). Theriogenology 2003; 59: 95–106
   PubMed Web of Science ®Google Scholar
• Sagen J, Wang H, Pappas GD. Adrenal medullary implants in the rat spinal cord reduce nociception in a chronic pain model. Pain 1990; 42: 69–79
   PubMed Web of Science ®Google Scholar
• Ortega-Alvaro A, Gibert-Rahola J, Chover AJ, et al. Effect of amitriptyline on the analgesia induced by adrenal medullary tissue transplanted in the rat spinal subarachnoid space as measured by an experimental model of acute pain. Exp Neurol 1994; 130: 9–14
   PubMed Web of Science ®Google Scholar
• Ortega-Alvaro A, Gibert-Rahola J, Mel lado-Fernandez ML, et a/. The effects of different monoaminergic antidepressants on the analgesia induced by spinal cord adrenal medullary transplants in the formal in test in rats. Anesth Analg 1997; 84: 816–820
   PubMed Web of Science ®Google Scholar
• Wang XT, Unnerstall JR, Ibuki T, et a/. Comparison of tyrosine hydroxylase and preproenkephalin expression in rat adrenal medullary explants in vitro and transplanted into subarachnoid space. Exp Neurol 2000; 161: 346–360
   PubMed Web of Science ®Google Scholar