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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 27, 2005 - Issue 2
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Articles

Adenosinergic mechanisms underlying recovery of diaphragm motor function following upper cervical spinal cord injury: potential therapeutic implications

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Pages 195-205 | Published online: 19 Jul 2013

REFERENCES

  • Splaingard ML, Frates RC Jr, Harrison GM, et al. Home positive-pressure ventilation. Twenty years' experience. Chest 1983; 84: 376–382
  • Wicks AB, Menter RR. Long term outlook in quadriplegic patients with initial ventilator dependency. Chest 1990; 90: 406–410
  • Bach JR, Alba AS. Noninvasive options for ventilatory support of the traumatic high level quadriplegic patient. Chest 1990; 98: 613–619
  • ManseL J, Norman JR. Respiratory complications and management of spinal cord injuries. Chest 1990; 97: 1446–1452
  • Claxton AR, Wong DT, Chung F, et al. Predictors of hospital mortability and mechanical ventilation in patients with cervical spinal injury. Can J Anaesth 1998; 45: 144–149
  • Frankel HL, Coll JR, Charlifue SW, et al. Long term survival of spinal cord: a fifty year investigation. Spinal Cord 1998; 36: 266–274
  • Rosenbleuth A, Ortiz T. The crossed respiratory impulse to the phrenic. Am J Physiol 1936; 117: 495–513
  • Aserinsky E. Effects of usage of a dormant respiratory nerve pathway upon its subsequent activity. Exp Neurol 1961; 3: 467–475
  • Goshgarian HG. Developmental plasticity in the respiratory pathway of the adult rat. Exp Neurol 1979; 66: 547–555
  • Goshgarian HG, Guth L. Demonstration of functionally ineffective synapses in the guinea pig spinal cord. Exp Neurol 1977; 57: 211–225
  • Goshgarian HG, Moran MF, Prcevski P. Effect of cervical spinal cord hemisection and hemidiaphragm paralysis on arterial blood gases, pH, and respiratory rate in the adult rat. Exp Neurol 1986; 93: 440–5
  • Nantwi KD, El-Bohy AA, Schrimsher GW, et al. Spontaneous functional recovery in a paralysed hemidiaphragm following cervical spinal cord hemisection. Neurorehab Neural Repair 1999; 13: 225–234
  • Moreno DE, Yu X-J, Goshgarian HG. Identification of the axon pathways which mediate functional recovery of a paralysed hemidiaphragm following spinal cord hemisection in the adult rat. Exp Neurol 1992; 116: 219–228
  • Lewis JL, Brookhart JM. Significance of the crossed phrenic phenomenon. Neurophysiol 1951; 166: 241–254
  • Nantwi KD, El-Bohy A, Goshgarian HG. Actions of systemic theophylline on hemdiaphragmatic recovery in rats following cervical spinal cord hemisection. Exp Neurol 1996; 140: 53–59
  • Lakshminarayan S, Sahn SA, Weil JV. Effect of aminophylline on ventilatory responses in normal man. Am Rev Resp Dis 1978; 117: 33–38
  • Richmond GH. Actions of caffeine and aminophylline as respiratory stimulants in man. J Appl Physiol 1949; 2: 16–23
  • Higbee MD, Kumar M, Galant SP. Stimulation of endogenous catecholamine release by theophylline: a proposed additional mechanism of action of theophylline effects. J Allergy Clin Immunol 1982; 70: 377–382
  • Eldridge FL, Millhorn DE, Waldrop TG, et al. Mechanisms of respiratory effects of methylxanthines. Resp Physiol 1983; 53: 239–261
  • Woodcock AA, Johnson MA, Geddes DM. Theophylline prescrib-ing, serum concentrations and toxicity. Lancet 1983; 2: 610–613
  • Borga O, Andersson KK, Edholm LE, et al. Enprofylline kinetics in healthy subjects after single doses. Clin Pharmacol Ther 1983; 34: 799–804
  • Nantwi KD, Goshgarian HG. Theophylline-induced recovery in a hemidiaphragm paralysed by hemisection in rats contribution of adenosine receptors. Neuropharmacology 1998; 37: 113–121
  • Nantwi KD, Goshgarian HG. Effects of chronic theophylline injections on recovery of hemidiaphragmatic function after cervical spinal cord injury in adult rats. Brain Res 1998; 789: 126-129
  • Sieck GC, Fournier M. Diaphragm motor recruitment during ventilatory and nonventilatory behaviors. J Appl Physiol 1989; 66: 2539–45
  • Nantwi KD, Goshgarian HG. Alkylxanthine-induced recovery of respiratory function following cervical spinal cord injury in adult rats. Exp Neurol 2001; 168: 123–134
  • Evoniuk G, Von Borstel RW, Wurtman RJ. Antagonism of the cardiovascular effects of adenosine by caffeine orsulfophenyl)theophyl I ine. J Pharmacol Exp Ther 1986; 240: 428–432
  • Nikodijevic O, Sarges R, Daly JW, et al. Behavioral effects of Al-and A2-selective adenosine agonists and antagonists. Evidence for synergism antagonism. ] Pharmacol Exp Ther 1991; 259: 286–294
  • Thomas T, Elnazir BK, Marshall JM. Differentiation of the peripherally mediated from the centrally mediated influences of adenosine in the rat during systemic hypoxia. Exp Physiol 1994; 79: 809–822
  • Maxwell DL, Fuller RW, Nolop KB, et al. Effects of adenosine on ventilatory responses to hypoxia and hypercapnia in humans. J Appl Physiol 1986; 61: 1762–1766
  • Fuller RW, Maxwell DL, Conradson TB, et al. Circulatory and respiratory effects of infused adenosine in conscious man. Br] Clin Pharmacol 1987; 24: 306–317
  • Reid PG, Watt AH, Penney WJ, et al. Plasma adenosine concentrations during adenosine-induced respiratory stimulation in man. Eur J Clin Pharmacol 1991; 40: 175–180
  • Dalziel HH, Westfall DP. Receptors for adenine nucleotides and nucleosides: subclassification, distribution and molecular char-acterization. Pharmacol Rev 1994; 46: 449–465
  • Jacobson KA, Van Galen PJM, Williams M. Adenosine receptors: pharmacology, structure-activity relationships, and therapeutic potential. ] Med Chem 1992; 35: 407–422
  • Zarrindast M-R, Naghipour B, Roushan-zamir F, et al. Effects of adenosine receptor agents on the expression of morphine with-drawal in mice. Eur J Pharmacol 1999; 369: 17–22
  • Nantwi KD, Goshgarian HG. Effects of specific adenosine receptor A1 and A2 agonists and antagonists in recovery of phrenic motor output following upper cervical spinal cord injury in adult rats. Clin Exp Physiol Pharmacol 2002; 29: 915–923
  • Howell LL. Effects of adenosine agonists on ventilation during hypercapnia, hypoxia and hyperoxemia in rhesus monkeys. J Pharmacol Exp Ther 1993; 265: 971–978
  • Bisserbe JC, Pascal O, Deckert J, et al. Potential use of DPCPX as a probe for in vivo localization of brain A1 adenosine receptors. Brain Res 1992; 599: 6–12
  • McQueen DS, Ribeiro JA. On the specificity and type of receptor involved in carotid body chemoreceptor activation by adenosine in the cat. Br J Pharmacol 1983; 80: 34–354
  • Sheardown MJ, Knutsen US. Unexpected neuroprotection observed with the adenosine A2A receptor agonist CGS 21680. Drug Dev Res 1996; 39: 108–14
  • Ribeiro JA, Cunha RA, Correia-de-Sa P, et al. Purinergic regulation of acetylcholine release. Prog Brain Res 1996; 109: 231–241
  • Ribeiro, JA. Adenosine A2A receptor interactions with receptors for other neurotransmitters and neuomodulators. Eur J Pharmacol 1999; 375: 101–103
  • Dixon AK, Guvitz AK, Sirinathsinghji DJS, et al. Tissue distribution of adenosine receptor mRNA in the rats. Br] Pharmacol 1996; 118: 1461 —1468
  • Cunha RA, Johansson B, Constantino B, et al. Evidence fore high-affinity binding sites for the adenosine A2A receptor agonist, 3[H]CGS 21680 in the rat hippocampus and cerebral cortex that are different from striatal A2A receptors. Naunyn Schmied Arch Pharmacol 1996; 353: 261–271
  • Dong X-W, Feldman JL. Modulation of inspiratory drive to phrenic motoneurons by presynaptic adenosine A1 receptors. J Neurosci 1995; 15: 3458–3467
  • O'Kane EM, Stone TVV. Interactions between adenosine Al and A2 receptor mediated responses in the rat hippocampus in vitro. Eur J Pharmacol 1998; 362: 17–25
  • Lopes LV, Cunha RA, Ribeiro JA. Cross talk between Al and A2 adenosine receptors in the hippocampus and cortex of young adult and old rats. ] Neurophysiol 1999; 82: 3196–3203
  • Eldridge FL, Mil lhorn DE, Kiley JP. Antagonism by theophylline of respiratory inhibition induced by adenosine. J Appl Physiol 1985; 59: 1428–1433
  • McQueen DA, Ribeiro JA. Effect of adenosine on carotid chemore-ceptor activity in the cat. Br J Pharmacol 1981; 74: 129–136
  • Brian JK, Chau A. Fetal cardiovascular and breathing responses to an adenosine A2a receptor agonist in sheep. Am J Physiol 1998; 274: R152—R159
  • Luglianai R, Whipp BJ, Seard C, et al. Effect of bilateral carotid-body resection on ventilatory control at rest and during exercise in man. N Engl J Med 1971; 285: 1105–1111
  • Watt AH, Routledge PA. Adenosine stimulates respiration in man. Br J Clin Pharmacol 1985; 20: 503–506
  • Monteiro EC, Ribeiro JA. Ventilatory effects of adenosine mediated by carotid body chemoreceptors in the rat. Naunyn Schmied Arch Pharmacol 1987; 335: 143–148
  • Monti D, Carley DW, Radulovacki M. p-SPA, a peripheral adenosine Al analog, reduces sleep apnea in rats. Pharmacol Biochem Behav 1996; 53: 341–345
  • Carley DW, Radulovacki M. Role of peripheral adenosine A(1) receptors in the regulation of apneas in rats. Exp. Neurol 1999; 159: 545–550
  • Olson EB Jr, Vidruk EH, Dempsey JA. Carotid body excision significantly changes ventilatory control in awake rats. J Appl Physiol 1988; 64: 666–671
  • Gauda EB. Expression and localization of A2A and Al-adenosine receptor genes in the carotid body and petrosal ganglia. A2A and Al -adenosine receptor mRNA in the rat carotid body. Adv Exp Med Biol 2000; 475: 549–558
  • Gauda EB, Northington FJ, Linden J, et al. Differential expression of A2A, Al-adenosine and D2-dopamine receptor genes in rat peripheral chemoreceptors during postnatal development. Brain Res 2000; 872: 1–10
  • Kobayashi S, Conforti L, Millhorn DE. Gene expression and function of adenosine A2A receptor in the rat carotid body. Am J Physiol 2000; 279: L273—L282
  • Rocher A, Gonzalez C, Almaraz L. Adenosine inhibits L-type Ca+ current and catecholamine release in the rabbit carotid body chemoreceptor cells. Eur J Neurosci 1999; 11: 673–681
  • Bae H, Nantwi KD, Goshgarian HG. Recovery of respiratory function following C2 hemisection and carotid body denervation in adult rats: influence of peripheral adenosine receptors. Exp Neurol 2005; 191: 94–103
  • Reppert SM, Weaver DR, Stehle JH, et al. Molecular cloning and characterization of a rat Al-adenosine receptor that is widely expressed in brain and spinal cord. Mol Endocrinol 1991; 5: 1037–1048
  • Fastbom J, Fredholm BB. Regional differences in the effect of guanine nucleotides on agonist and antagonist binding to adenosine Al-receptors in rat brain, as revealed by autoradio-graphy. Neuroscience 1990; 34: 759–769
  • Basura GJ, Nantwi KD, Goshgarian HG. Theophylline-induced respiratory recovery following cervical spinal cord hemisection is augmented by serotonin 2 receptor stimulation. Brain Res 2002; 956: 1–13
  • Nantwi KD, Basura GJ, Goshgarian HG. Effects of long term theophylline exposure on recovery of respiratory function and expression of adenosine Al mRNA in cervical spinal cord hemisected adult rats. Exp Neurol 2003; 182: 232–239
  • Nantwi KD, Basura GJ, Goshgarian HG. Adenosine Al receptor mRNA expression and the effects of systemic theophylline administration on respiratory function 4 months after C2 hemisec-tion. J Spin Cord Med 2003; 26: 364–371
  • Johansson B, Ahlberg S, Van der Ploeg I, et al. Effects of long term caffeine treatment on Al and A2 adenosine receptor binding and on mRNA levels in rat brain. Naunyn Schmied Arch Pharamcol 1993; 347: 407–414
  • Johansson B, Georgiev V, Lindstrom K, et al. Al and A2 adenosine receptors and al mRNA in mouse brain: effect of long term caffeine treatment. Brain Res 1997; 762: 153–164
  • Golder FJ, Fuller DD, Davenport PW, et al. Respiratory motor recovery after unilateral spinal cord injury: eliminating crossed phrenic activity decreases tidal volume and increases contralateral phrenic motor output. I Neurosci 2003; 23: 2494–2501
  • Cheshire DJE. Respiratory management in acute traumatic tetra-plegia. Paraplegia 1964; 1: 252–261
  • Cheshire DJE, Coats DA. Respiratory and metabolic management in acute tetraplegia. Paraplegia 1966; 4: 1–23
  • Ohry A, Molho M, Rozin R. Alterations of pulmonary function in spinal cord injured patients. Paraplegia 1975; 13: 101–108
  • Slack RS, Shucart W. Respiratory dysfunction associated with traumatic injury to the central nervous system. Clin Chest Med 1994; 15: 739–749
  • Carter RE, Donovan E, Halstead L, et al. Comparative study of electrophrenic nerve stimulation and mechanical ventilatory support in traumatic spinal cord injury. Paraplegia 1987; 25: 86–91
  • Ferguson GT, Narendra K, Lattin CD, et al. Clinical effects of theophyl I ine on inspiratory muscle drive in tetraplegia. Neurorehab Neural Rep 1999; 13: 191–197

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