References
- Ataga KI, Orringer EP. Hypercoagulability in sickle cell disease: acurious paradox. Am J Med 2003; 115: 721–728.
- Barker JE, Wandersee NJ. Thrombosis in heritable hemolytic disorders. Curr Opin Hematol 1999; 6: 71–75.
- Francis RB Jr. Platelets, coagulation, and fibrinolysis in sickle celldisease: their possible role in the vascular occlusion. Blood Coagul Fibrinolysis 1991; 2: 341–353.
- Eldor A, Rachmilewitz EA. The hypercoagulable state in thalassemia. Blood 2002; 99: 36–43.
- Kuypers FA, Lewis RA, Hua M et al. Detection of altered membrane phospholipid asymmetry in subpopulations of human red blood cells using fluorescently labeled annexin V. Blood 1996, 87: 1179–1187.
- Middelkoop E, Lubin BH, Bevers EM et al. Studies on sickled erythrocytes provide evidence that the asymmetric distribution of phosphatidylserine in the red cell membrane is maintained by both ATP-dependent translocation and interaction with membrane skeletal proteins. Brioche Biophys Acta 1988; 937: 281–288.
- Tait JF, Gibson D. Measurement of membrane phospholipid asymmetry in normal and sickle cell erythrocytes by means of annexin V binding. J Lab Clin Med 1994; 123: 741–748.
- Atichartakarn V, Angchaisuksiri P, Aryurachai K et al. Relationship between hypercoagulable state and erythrocyte phosphatidylserine exposure in splenectomized haemoglobin E/ beta-thalassaemic patients. Br J Haematol 2002; 118: 893–898.
- Hall C, Richards S, Hillmen P. Primary prophylaxis with warfarinprevents thrombosis in paroxysmal nocturnal hemoglobinuria (PNH). Blood 2003; 102: 3587–3591.
- Rother RP, Bell L, Hillmen P, Gladwin MT. The clinical sequelae of intravascular hemolysis and extracellular plasma hemoglobin: a novel mechanism of human disease. JAMA 2005; 293: 1653–1662.
- Bunn HF. Pathogenesis and treatment of sickle cell disease. N EnglJ Med 1997; 337: 762–769.
- Wang WC, Morales KH, Scher CD et al. Effect of long-term transfusion on growth in children with sickle cell anemia: results of the STOP trial. J Pediatr 2005; 147: 244–247.
- Adams RJ, McKie VC, Hsu L et al. Prevention of a first stroke by transfusions in children with sickle cell anemia and abnormal results on transcranial Doppler ultrasonography. N Engl J Med 1998; 339: 5–11.
- Gulbis B, Haberman D, Dufour D et al. Hydroxyurea for sickle cell disease in children and for prevention of cerebrovascular events: the Belgian experience. Blood 2005; 105: 2685–2690.
- Ware RE, Zimmerman SA, Sylvestre PB et al. Prevention of secondary stroke and resolution of transfusional iron overload in children with sickle cell anemia using hydroxyurea and phlebot-omy. J Pediatr 2004; 145: 346–352.
- Ferster A, Tahriri P, Vermylen C et al. Five years of experience with hydroxyurea in children and young adults with sickle cell disease. Blood 2001; 97: 3628–3632.
- Yang YM, Pace B, Kitchens D, Ballas SK, Shah A, Baliga BS. BFU-E colony growth in response to hydroxyurea: correlation between in vitro and in vivo fetal hemoglobin induction. Am J Hematol 1997; 56: 252–258.
- Steinberg MH, Lu ZH, Barton FB, Terrin ML, Charache S, Dover GJ. Multicenter study of hydroxyurea. Fetal hemoglobin in sickle cell anemia: determinants of response to hydroxyurea. Blood 1997; 89: 1078–1088.
- Pullarkat V, Ngo M, Iqbal S, Espina B, Liebman HA. Detection of lupus anticoagulant identifies patients with autoimmune haemoly-tic anaemia at increased risk for venous thromboembolism. Br J Haematol 2002; 118: 1166–1169.
- Hendrick AM. Autoimmune haemolytic anaemia--a high-risk disorder for thromboembolism? Hematology 2003; 8: 53–56.
- Koury MJ, Koury ST, Kopsombut P, Bondurant MC. In vitro maturation of nascent reticulocytes to erythrocytes. Blood 2005; 105: 2168–2174.
- Come SE, Shohet SB, Robinson SH. Surface remodeling of reticulocytes produced in response to erythroid stress. Nat New Biol 1972; 236: 157–158.
- Patel VP, Ciechanover A, Platt O, Lodish HF. Mammalian reticulocytes lose adhesion to fibronectin during maturation to erythrocytes. Proc Nail Acad Sci USA 1985; 82: 440–444.
- Chasis JA, Prenant M, Leung A, Mohandas N. Membrane assembly and remodeling during reticulocyte maturation. Blood 1989; 74: 1112–1120.
- Johnstone RM, Mathew A, Mason AB, Teng K. Exosome formation during maturation of mammalian and avian reticulo-cytes: evidence that exosome release is a major route for externalization of obsolete membrane proteins. J Cell Physiol 1991; 147: 27–36.
- Rabesandratana H, Toutant JP, Reggio H, Vidal M. Decay-accelerating factor (CD55) and membraneinhibitor of reactive lysis (CD59) are released within exosomes during in vitro maturation of reticulocytes. Blood 1998; 91: 2573–2580.
- Rieu S, Geminard C, Rabesandratana H, Sainte-Marie J, Vidal M. Exosomes released during reticulocyte maturation bind to fibro-nectin via integrin alpha 4 beta 1 . Eur J Biochem 2000; 267: 583–590.
- Heynen MJ, Tricot G, Verwilghen RL. Autophagy of mitochon-dria in rat bone marrow erythroid cells: relation to nuclear extrusion. Cell Tissue Res 1985; 239: 235–239.
- Gasko O, Danon D. Deterioration and disappearance of mito-chondria during reticulocyte maturation. Exp Cell Res 1972; 75: 159–169.