1,267
Views
10
CrossRef citations to date
0
Altmetric
Hemoglobinopathy

Usefulness of red blood cell flags in diagnosing and differentiating thalassemia trait from iron-deficiency anemia

, , &
Pages 253-256 | Published online: 18 Jul 2013

References

  • Jolobe OMP. Prevalence of hypochromia (without microcytosis) vs microcytosis (without hypochromia) in iron deficiency. Clinical & Laboratory Haematology 2000; 22: 79.
  • Bessman JD, McClure S, Bates J. Distinction of microcytic disorders: comparison of expert, numerical-discriminant, and microcomputer analysis. Blood Cells 1989; 15(3): 533–540.
  • Eldibany MM, Totonchi KF, Joseph NJ, Rhone D. Usefulness ofcertain red blood cell indices in diagnosing and differentiating thalassemia trait from iron-deficiency anemia. Am J Clin Pathol 1999; 111(5): 676–682.
  • Noronha JF, Grotto HZ.Measurement of reticulocyte and red blood cell indices in patients with iron deficiency anemia and beta-thalassemia minor. Clin Chem Lab Med 2005; 43(2): 195–197.
  • Jimenez CV. Iron-deficiency anemia and thalassemia trait differ-entiated by simple hematological tests and serum iron concentra-tions. Clin Chem 1993; 39(11 Pt 1): 2271–2275.
  • Lima CS, Reis AR, Grotto HZ, Saad ST, Costa FF. Comparisonof red cell distribution width and a red cell discriminant function incorporating volume dispersion for distinguishing iron Deficiency from beta thalassemia trait in patients with microcytosis. Sao Paulo Med J 1996; 114(5): 1265–1269.
  • Green R, King R. A new red cell discriminant incorporating volume dispersion for differentiating iron deficiency anemia from thalassemia minor. Blood Cells 1989; 15(3): 481–495.
  • England JM, Fraser P. Discrimination between iron-deficiency andheterozygous-thalassaemia syndromes in differential diagnosis of microcytosis. Lancet 1979; 1(8108): 145–148.
  • Koenig HM.Classification of microcytic anemia by fluorometric analysis of free erythrocyte porphyrins (FEP). Ann Clin Res 1976; Suppl 17: 151–155.
  • Han P, Fung KP. Discriminant analysis of iron deficiency anaemiaand heterozygous thalassaemia traits: a 3-dimensional selection of red cell indices. Clin Lab Haematol 1991; 13(4): 351–362.
  • Cunningham LO, Rising JA. Erythrocytic microcytosis: clinical implications in 100 patients. Am J Med Sci 1977; 273(2): 149–155.
  • Junca J, Flores A, Roy C, Alberti R, Milla F. Red cell distribution width, free erythrocyte protoporphyrin, and England-Fraser index in the differential diagnosis of microcytosis due to iron deficiency or beta-thalassemia trait. Hematol Pathol 1991; 5(1): 33–36.
  • Bessman JD, Feinstein DI. Quantitative anisocytosis as a discriminant between iron deficiency and thalassemia minor. Blood 1979; 53(2): 288–293.
  • Houwen B. The use of inference strategies in the differential diagnosis of microcytic anemia. Blood Cells 1989; 15(3): 509–532.
  • Marsh WL Jr, Bishop JW, Darcy TP. Evaluation of red cell volume distribution width (RDW). Hematol Pathol 1987; 1(2): 117–123.
  • d'Onofrio G, Zini G, Ricerca BM, Mancini S, Mango G. Automated measurement of red blood cell microcytosis and hypochromia in iron deficiency and beta-thalassemia trait. Arch Pathol Lab Med 1992; 116(1): 84–89
  • Robertson EP, Pollock A, Yau KS, Chan LC. Use of technicon H1 technology in routine thalassaemia screening. Med Lab Sci 1992; 49(4): 259–264.
  • Jimenez CV, Minchinele J, Ros J. New indices from the H*2 analyser improve differentiation between heterozygous beta or delta beta thalassaemia and iron-deficiency anaemia. Clin Lab Haematol 1995; 17(2): 151–155.
  • Bentley SA, Ayscue LH, Watson JM, Ross DW. The clinical utility of discriminant functions for the differential diagnosis of micro-cytic anemias. Blood Cells 1989; 15(3): 575–584.
  • Kotisaari S, Romppanen J, Penttild I, Punnonen K. The Advia 120 red blood cell and reticulocyte indices are useful in diagnosis of iron-deficiency anemia. Eur J Haematol 2002; 68(3): 150.
  • Yermiahu T, Ben-Shalom M, Porath A. Quantitative determina-tions of microcytic-hypochromic red blood cell population and glycerol permeability in iron-deficiency anemia and beta thalasse-mia minor. Ann Hematol 1999; 78(10): 468–471.
  • Laso FJ, Mateos F, Ramos R, Herrero F, Pérez-Arellano JL, Gonzalez-Buitrago JM. Amplitude of the distribution of erythro-cyte size in the differential diagnosis of microcytic anemia. Med Clin (Bare) 1990; 94(1): 1–4.
  • Johnson CS, Tegos C, Beutler E. Thalassemia minor: routine erythrocyte measurements and differentiation from iron deficiency. Am J Clin Pathol 1983; 80(1): 31–36.
  • Lin CK, Lin JS, Chen SY, Jiang ML, Chia CF. Comparison of hemoglobin and red blood cell distribution width in the differential diagnosis of microcytic anemia. Arch Pathol Lab Med 1992; 116(10): 1030–1032.
  • Kotwal J, Saxena R, Choudhry VP, Dwivedi SN, Bhargava M. Erythrocyte indices for discriminating thalassaemic and non-thalassaemic microcytosis in Indians. Natl Med J India 1999; 12(6): 266–267.
  • Romero Artaza J, Carbia CD, Ceballo MF, Diaz NB. Red cell distribution width (RDW): its use in the characterization of microcytic and hypochromic anemias. Medicina (B Aires) 1999; 59(1): 17–22.
  • Cesana BM, Maiolo AT, Gidiuli R, Damilano I, Massaro P, Polli EE. Relevance of red cell distribution width (RDW) in the differential diagnosis of microcytic anaemias. Clin Lab Haematol 1991; 13(2): 141–151.
  • Sonati Mde F, Grotto HZ, Kimura EM, Costa FF. Differentiation between heterozygotic beta-thalassemia and iron deficiency ane-mia. Rev Assoc Med Bras 1993; 39(4): 221–223.
  • Demir A, Yarali N, Fisgin T, Duru F, Kara A. Most reliable indices in differentiation between thalassemia trait and iron deficiency anemia. Pediatr Int 2002; 44(6): 612–616.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.