72
Views
2
CrossRef citations to date
0
Altmetric
Hemostasis and Thrombosis

Heparin induced thrombocytopenia with thrombosis: a two step process?

Pages 181-182 | Published online: 18 Jul 2013

References

  • Amiral J, Bridey F, Dreyfus Met al. Platelet factor 4 complexed to heparin is the target for antibodies generated in heparin- induced thrombocytopenia. Thromb Haemost 1992; 68: 95–96.
  • Arepally GM, Ortel TL. Heparin-induced thrombocytopenia. N Engl J Med 2006; 355: 809–817.
  • Arepally GM, Mayer IM. Antibodies from patients with heparin-induced thrombocytopenia stimulate monocytic cells to express tissue factor and secrete interleukin-8. Blood 2001; 98: 1252–1254.
  • Pouplard C, Iochmann S, Renard B et al. Induction of monocytetissue factor expression by antibodies to heparin-platelet factor 4 complexes developed in heparin-induced thrombocytopenia. Blood 2001; 97: 3300–3302.
  • Kelton JG. The pathophysiology of heparin-induced thrombocy-topenia: biological basis for treatment. Chest 2005; 127 (Suppl. 2): S9—S20.
  • Warkentin TE, Levine MN, Hirsh J et al. Heparin induced thrombocytopenia in patients treated with low-molecular-weight heparin or unfractionated heparin. N Engl J Med 1995; 332: 1330–1335.
  • Ortel TL, Chong BH. New treatment options for heparin-inducedthrombocytopenia. Semin Hematol 1998; 35: 26–34.
  • Osterman DG, Griffin GL, Senior RM, Kaiser ET, Deuel TF. Thecarboxylterminal tridecapeptide of platelet factor 4 is potent chemotactic agent for monocytes. Biochem Biophys Res Commun 1982; 107: 130–135.
  • Deuel TF, Senior RM, Chang D, Griffin GL, Heinrikson RL, Kaiser ET. Platelet factor 4 is chemotactic for neutrophils and monocytes. Proc Natl Acad Sci USA 1981; 78: 4584–4587.
  • Xia CQ, Kao U. Effect of CXC chemokine platelet factor 4 on differentiation and function of monocyte-derived dendritic cells. Int Immunol 2003; 15: 1007–1015.
  • Lyberg T, Prydz H, Baklien K, Hoyeraal HM. Effect of immune complex-containing sera from patients with rheumatic diseases on thromboplastin activity of monocytes. Thromb Res 1982; 25: 193–202.
  • Reverter JC, Tassies D, Font J et al. Hypercoagulable state in patients with antiphospholipid syndrome is related to high induced tissue factor expression on monocytes and to low free proteins. Arterioscler Thromb Vase Biol 1996; 16: 1319–1326.
  • Rivers RP, Hathaway WE, Weston WL. The endotoxin-induced coagulant activity of human monocytes. Br J Haematol 1975; 30: 311–316.
  • Khajuria A, Houston DS. Induction of monocyte tissue factor expression by homocysteine: a possible mechanism for thrombosis. Blood 2000; 96: 966–972
  • Schwertz H, Tolley ND, Foulks JM et al. Signal-dependent splicing of tissue factor pre-mRNA modulates the thrombogenicity of human platelets. J Exp Med 2006; 203: 2433–2440.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.