Ligation of CD44 with low-molecular-weight hyaluronan and a monoclonal antibody leads to inhibition of drug-induced apoptosis in a human myeloid cell line

References

• Droz D, Patey N, Paraf F, Chretien Y, Gogusev J. Composition of extracellular matrix and distribution of cell adhesion molecules in renal cell tumors. Lab Invest 1994; 71: 710–718.
   PubMed Web of Science ®Google Scholar
• Simmons PJ, Levesque JP, Zannettino AC. Adhesion molecules inhaemopoiesis. Baillieres Clin Haematol 1997; 10: 485–505.
   PubMed Web of Science ®Google Scholar
• Miyake K, Medina KL, Hayashi S, Ono S, Hamaoka T, Kincade PW. Monoclonal antibodies to Pgp-1/CD44 block lympho-hemopoiesis in long-term bone marrow cultures. J Exp Med 1990; 171: 477–488.
   PubMed Web of Science ®Google Scholar
• Miyake K, Weissman IL, Greenberger JS, Kincade PW. Evidencefor a role of the integrin VLA-4 in lympho-hemopoiesis. J Exp Med 1991; 173: 599–607.
   PubMed Web of Science ®Google Scholar
• Larkin J, Renukaradhya GJ, Sriram V, Du W, Gervay-Hague J, Brutkiewicz RR. CD44 differentially activates mouse NK T cells and conventional T cells. J Immunol 2006; 177: 268–279.
   PubMed Web of Science ®Google Scholar
• Rafi A, Nagarkatti M, Nagarkatti PS. Hyaluronate-CD44 inter-actions can induce murine B-cell activation. Blood 1997; 89: 2901–2908.
   PubMed Web of Science ®Google Scholar
• Termeer C, Averbeck M, Hara H et al. Targeting dendritic cells with CD44 monoclonal antibodies selectively inhibits the prolif-eration of naive CD4 + T-helper cells by induction of FAS-independent T-cell apoptosis. Immunology 2003; 109: 32–40.
   PubMed Web of Science ®Google Scholar
• Sugahara KN, Murai T, Nishinakamura H, Kawashima H, Saya H, Miyasaka M. Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells. J Biol Chem 2003; 278: 32259–32265.
   PubMed Web of Science ®Google Scholar
• Yokota A, Ishii G, Sugaya Y, Nishimura M, Saito Y, Harigaya K. Expression of exon v6-containing CD44 isoforms is related to poor prognosis of acute myelocytic leukemia. Hematol Oncol 1998; 16: 131–141.
   PubMed Web of Science ®Google Scholar
• Jin L, Hope KJ, Zhai Q, Smadja-Joffe F, Dick JE. Targeting of CD44 eradicates human acute myeloid leukemic stem cells. Nat Med 2006; 12: 1167–1174.
   PubMed Web of Science ®Google Scholar
• Krause DS, Lazarides K, von Andrian UH, Van Etten RA. Requirement for CD44 in homing and engraftment of BCR-ABL-expressing leukemic stem cells. Nat Med 2006; 12: 1175–1180.
   PubMed Web of Science ®Google Scholar
• Gallagher JT, Spooncer E, Dexter TM. Role of the cellular matrix in haemopoiesis. I. Synthesis of glycosaminoglycans by mouse bone marrow cell cultures. J Cell Sci 1983; 63: 155–171.
   PubMed Web of Science ®Google Scholar
• Allouche M, Bettaieb A, Vindis C, Rousse A, Grignon C, Laurent G. Influence of Bc1-2 overexpression on the ceramide pathway in daunorubicin-induced apoptosis of leukemic cells. Oncogene. 1997; 14: 1837–1845.
   PubMed Web of Science ®Google Scholar
• Schenck P, Schneider S, Miehlke R, Prehm P. Synthesis and degradation of hyaluronate by synovia from patients with rheumatoid arthritis. J Rheumatol 1995; 22: 400–405.
   PubMed Web of Science ®Google Scholar
• Forrester JV, Balazs EA. Inhibition of phagocytosis by high molecular weight hyaluronate. Immunology 1980; 40: 435446.
   Web of Science ®Google Scholar
• Hodge-Dufour J, Noble PW, Horton MR et al. Induction of IL-12 and chemokines by hyaluronan requires adhesion-dependent priming of resident but not elicited macrophages. J Immunol 1997; 159: 2492–2500.
   PubMed Web of Science ®Google Scholar
• Nakano K, Saito K, Mine S, Matsushita S, Tanaka Y. Engagement of CD44 up-regulates Fas ligand expression on T cells leading to activation-induced cell death. Apoptosis 2007; 12: 45–54.
   PubMed Web of Science ®Google Scholar
• Koeffler HP, Billing R, Lusis Ai, Sparkes R, Golde DW. An undifferentiated variant derived from the human acute myelogen-ous leukemia cell line (KG-1). Blood 1980; 56: 265–273.
   PubMed Web of Science ®Google Scholar
• Denizot F, Lang R. Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J Immunol Methods 1986; 89: 271–277.
   PubMed Web of Science ®Google Scholar
• Koopman G, Reutelingsperger CP, Kuijten GA, Keehnen RM, Pals ST, van Oers MH. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood 1994; 84: 1415–1420.
   PubMed Web of Science ®Google Scholar
• Allouche M, Charrad RS, Bettaieb A, Greenland C, Grignon C, Smadja-Joffe F. Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells. Blood 2000; 96: 1187–1190.
   PubMed Web of Science ®Google Scholar
• Laskin DL, Soltys RA, Berg RA, Riley DJ. Activation of alveolar macrophages by native and synthetic collagen-like polypeptides. Am J Respir Cell Mol Biol 1994; 10: 58–64.
   PubMed Web of Science ®Google Scholar
• Slevin M, Krupinski J, Kumar S, Gaffney J. Angiogenic oligosaccharides of hyaluronan induce protein tyrosine kinase activity in endothelial cells and activate a cytoplasmic signal transduction pathway resulting in proliferation. Lab Invest 1998; 78: 987–1003.
   PubMed Web of Science ®Google Scholar
• Montesano R, Kumar S, Orci L, Pepper MS. Synergistic effect of hyaluronan oligosaccharides and vascular endothelial growth factor on angiogenesis in vitro. Lab Invest 1996; 75: 249–262.
   PubMed Web of Science ®Google Scholar
• Rooney P, Kumar S. Inverse relationship between hyaluronan and collagens in development and angiogenesis. Differentiation 1993; 54: 1–9.
   PubMed Web of Science ®Google Scholar
• Anstee DJ, Gardner B, Spring FA et al. New monoclonal antibodies in CD44 and CD58: their use to quantify CD44 and CD58 on normal human erythrocytes and to compare the distribution of CD44 and CD58 in human tissues. Immunology 1991; 74: 197–205.
   PubMed Web of Science ®Google Scholar
• Denning S, Telen M, Liao H, Haynes B. CD44H and CD44R cluster report. In: Schossman S, Boumsell L and Gilks W (ed) Leukocyte typing V. white cell differentiation antigens. Oxford: Oxford University Press, 1995; 1713–1719.
   Google Scholar
• Bendall Li, Kirkness J, Hutchinson A et al. Antibodies to CD44 enhance adhesion of normal CD34 + cells and acute myeloblastic but not lymphoblastic leukaemia cells to bone marrow stroma. Br J Haematol 1997; 98: 828–837.
   PubMed Web of Science ®Google Scholar
• Oostendorp RA, Spitzer E, Brandl M, Eaves CJ, Dormer P. Evidence for differences in the mechanisms by which antibodies against CD44 promote adhesion of erythroid and granulopoietic progenitors to marrow stromal cells. Br J Haematol 1998; 101: 436–445.
   PubMed Web of Science ®Google Scholar
• Charrad RS, Li Y, Delpech B et al. Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia. Nat Med 1999; 5: 669–676.
   PubMed Web of Science ®Google Scholar
• Lesley J, English N, Perschl A, Gregoroff J, Hyman R. Variant celllines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation. J Exp Med 1995; 182: 431–437.
   PubMed Web of Science ®Google Scholar
• Smadja-Joffe F, Legras S, Girard N et al. CD44 and hyaluronan binding by human myeloid cells. Leuk Lymphoma 1996; 21: 407–420, color plates following 528.
   PubMed Web of Science ®Google Scholar
• Legras S, Levesque JP, Charrad R et al. CD44-mediated adhesiveness of human hematopoietic progenitors to hyaluronan is modulated by cytokines. Blood 1997; 89: 1905–1914.
   PubMed Web of Science ®Google Scholar
• Hannun YA, Obeid LM. Ceramide: an intracellular signal for apoptosis. Trends Biochem Sci 1995; 20: 73–77.
   PubMed Web of Science ®Google Scholar
• Mansat V, Laurent G, Levade T, Bettaieb A, Jaffrezou JP. The protein kinase C activators phorbol esters and phosphatidylserine inhibit neutral sphingomyelinase activation, ceramide generation, and apoptosis triggered by daunorubicin. Cancer Res 1997; 57: 5300–5304.
   PubMed Web of Science ®Google Scholar