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Original Article

Impact of anti‐oxidant status and apoptosis on the induction phase of chemotherapy in childhood acute lymphoblastic leukemia

, , , , &
Pages 14-19 | Received 01 Feb 2010, Accepted 06 Apr 2010, Published online: 12 Nov 2013

References

  • Downing JR, Shannon KM. Acute leukemia: a pediatric perspective. Cancer Cell 2002; 2: 437–445.
  • Plasschaert SL, Kamps WA, Vellenga E, de Vries EG, de Bont ES. Prognosis in childhood and adult acute lymphoblastic leukaemia: a question of maturation? Cancer Treat Rev 2004; 30: 37–51.
  • Valko M, Rhodes CJ, Moncol J, Izakovic M, Mazur M. Free radicals, metals and antioxidants in oxidative stress-induced cancer. Chem Biol Interact 2006; 160: 1–40.
  • Valko M, Leibfritz D, Moncol J, Cronin MT, Mazur M, Telser J. Free radicals and antioxidants in normal physiological functions and human disease. Int J Biochem Cell Biol 2007; 39: 44–84.
  • Stocker R, Keaney JF. Role of oxidative modifications in atherosclerosis. Physiol Rev 2004; 84: 1381–1478.
  • Ridnour LA, Isenberg JS, Espey MG, Thomas DD, Roberts DD, Wink DA. Nitric oxide regulates angiogenesis through a functional switch involving thrombospondin-1. Proc Natl Acad Sci USA 2005; 102: 13147–13152.
  • Dröge W. Free radicals in the physiological control of cell function. Physiol Rev 2002; 82: 47–95.
  • Chapple IL. Reactive oxygen species and antioxidants in inflammatory diseases. J Clin Periodontol 1997; 24: 287–296.
  • Ghiselli A, Serafini M, Natella F, Scaccini C. Total antioxidant capacity as a tool to assess redox status: critical view and experimental data. Free Radic Biol Med 2000; 29: 1106–1114.
  • Mantovani G, Macciò A, Madeddu C, et al.. Antioxidant agents are effective in inducing lymphocyte progression through cell cycle in advanced cancer patients: assessment of the most important laboratory indexes of cachexia and oxidative stress. J Mol Med 2003; 81: 664–673.
  • Zandieh T, Safarifard A, Nikogoftar M. In vitro evaluation of cytarabin induced apoptosis in leukemic blasts. Iran J Allergy Asthma Immunol 2005; 4: 173–178.
  • Howes RM. [Internet]. Cancer, apoptosis and reactive oxygen species: a new paradigm. 2007 [cited 2010 Jan 15]. Available from: http://philica.com/display_article.php?article_id=86
  • Ziegler DS, Kung AL. Therapeutic targeting of apoptosis pathways in cancer. Curr Opin Oncol 2008; 20: 97–103.
  • Koracevic D, Koracevic G, Djordjevic V, Andrejevic S, Cosic V. Method for the measurement of antioxidant activity in human fluids. J Clin Pathol 2001; 54: 356–361.
  • Satoh K. Serum lipid peroxide in cerebrovascular disorders determined by a new colorimetric method. Clin Chim Acta 1978; 90: 37–43.
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351–358.
  • Lanzkowsky P. Leukemias. In: , Lanzkowsky P, (ed) Manual of pediatric hematology and oncology. 3rd ed. San Diego, CA: Academic Press, 2005; 359–411.
  • Battisti V, Maders LD, Bagatini MD, et al.. Measurement of oxidative stress and antioxidant status in acute lymphoblastic leukemia patients. Clin Biochem 2008; 41: 511–518.
  • Sharara GM, Adawy NM. Study of oxidative stress, antioxidant status and their relation to apoptosis in acute lymphoblastic leukemia. Bull Alex Fac Med 2005; 41: 729–736.
  • McEligot AJ, Yang S, Meyskens FL. Redox regulation by intrinsic species and extrinsic nutrients in normal and cancer cells. Annu Rev Nutr 2005; 25: 261–295.
  • Singh V, Ghalaut PS, Kharb S, Singh GP. Plasma concentrations of lipid peroxidation products in children with acute leukaemia. Indian J Med Sci 2001; 55: 215–217.
  • Sentürker S, Karahalil B, Inal M, et al.. Oxidative DNA base damage and antioxidant enzyme levels in childhood acute lymphoblastic leukemia. FEBS Lett 1997; 27: 286–290.
  • Mazor D, Abucoider A, Meyerstein N, Kapelushnik J. Antioxidant status in pediatric acute lymphocytic leukemia (ALL) and solid tumors: the impact of oxidative stress. Pediatr Blood Cancer 2008; 51: 613–615.
  • Malvy DJ, Arnaud J, Burtschy B, et al.. Antioxidant micronutrients and childhood malignancy during oncological treatment. Med Pediatr Oncol 1997; 29: 213–217.
  • Kennedy DD, Ladas EJ, Rheingold SR, Blumberg J, Kelly KM. Antioxidant status decreases in children with acute lymphoblastic leukemia during the first six months of chemotherapy treatment. Pediatr Blood Cancer 2005; 44: 378–385.
  • Małyszczak K, Tomasz W, Mazur G, et al.. ‘Anxiety and depressive symptoms in patients treated due to haematologic malignancies’. Psychiatr Pol 2005; 39: 33–40.
  • Devi GS, Prasad MH, Saraswathi I, Raghu D, Rao DN, Reddy PP. Free radicals antioxidant enzymes and lipid peroxidation in different types of leukemias. Clin Chim Acta 2000; 293: 53–62.
  • Nishiura T, Suzuki K, Kawaguchi T, et al.. Elevated serum manganese superoxide dismutase in acute leukemias. Cancer Lett 1992; 62: 211–215.
  • Papageorgiou M, Stiakaki E, Dimitriou H, et al.. Cancer chemotherapy reduces plasma total antioxidant capacity in children with malignancies. Leuk Res 2005; 29: 11–16.
  • Kennedy DD, Santella RM, Wang Q, Ladas EJ, Kelly KM. 8-oxo-dG elevated in children during leukemia treatment. Integr Cancer Ther 2004; 3: 301–309.
  • Drisko JA, Chapman J, Hunter VJ. The use of antioxidant therapies during chemotherapy. Gynecol Oncol 2003; 88: 434–439.
  • Al-Tonbary Y, Al-Haggar M, El-Ashry R, El-Dakroory S, Azzam H, Fouda A. Vitamin E and N-acetylcysteine as antioxidant adjuvant therapy in children with acute lymphoblastic leukemia. Adv Hematol 2009; 2009: 689639.
  • Jeanne A, Drisko JA, Chapman J, Hunter VJ. The use of antioxidant therapies during chemotherapy. Gynecol Oncol 2003; 88: 434–439.
  • Drabko K, Bojarska-Junak A, Kowalczyk J. ‘Activity of superoxide dismutase and glutathione peroxidase and concentrations of malonyldialdehyde, vitamin E, total antioxidant status and extracellular cytokines concentrations in children with acute lymphoblastic leukaemia (ALL)’. Med Wieku Rozwoj 2006; 10: 861–868.
  • Hunnisett A, Davies S, McLaren-Howard J, Gravett P, Finn M, Gueret-Wardle D. Lipoperoxides as an index of free radical activity in bone marrow transplant recipients. Preliminary observations. Biol Trace Elem Res 1995; 47: 125–132.
  • Al-Gayyar MM, Eissa LA, Rabie AM, El-Gayar AM. Measurements of oxidative stress status and antioxidant activity in chronic leukaemia patients. J Pharm Pharmacol 2007; 59: 409–417.
  • Liu T, Raetz E, Moos PJ, et al.. Diversity of the apoptotic response to chemotherapy in childhood leukemia. Leukemia 2002; 16: 223–232.
  • Aref S, Salama O, Al-Tonbary Y, Mansour A. Assessment of bcl-2 expression as modulator of fas mediated apoptosis in acute leukemia. Hematology 2004; 9: 113–121.
  • Klener PJr, Andera L, Klener P, Necas E, Zivný J. Cell death signalling pathways in the pathogenesis and therapy of haematologic malignancies: overview of apoptotic pathways. Folia Biol (Praha) 2006; 52: 34–44.
  • Carmody RJ, Cotter TG. Signalling apoptosis: a radical approach. Redox Rep 2001; 6: 77–90.
  • Suhara T, Kim HS, Kirshenbaum LA, Walsh K. Suppression of Akt signaling induces Fas ligand expression: involvement of caspase and Jun kinase activation in Akt-mediated Fas ligand regulation. Mol Cell Biol 2002; 22: 680–691.
  • Meyer LH, Karawajew L, Schrappe M, Ludwig WD, Debatin KM, Stahnke K. Cytochrome c-related caspase-3 activation determines treatment response and relapse in childhood precursor B-cell ALL. Blood 2006; 107: 4524–4531.
  • Hafez M, Al-Tonbary Y, El-Bayoumi MA, et al.. Markers of apoptosis and proliferation related gene products as predictors of treatment outcome in childhood acute lymphoblastic leukemia. Hematology 2007; 12: 209–218.
  • Brajusković G, Milić AS, Vukosavić S, et al.. ‘Apoptosis in chronic lymphocytic leukemia’. Vojnosanit Pregl 2002; 59: 47–52.
  • Holleman A, den Boer ML, Kazemier KM, Janka-Schaub GE, Pieters R. Resistance to different classes of drugs is associated with impaired apoptosis in childhood acute lymphoblastic leukemia. Blood 2003; 102: 4541–4546.
  • Matés JM, Sánchez-Jiménez FM. Role of reactive oxygen species in apoptosis: implications for cancer therapy. Int J Biochem Cell Biol 2000; 32: 157–170.
  • Nakazato T, Sagawa M, Yamato K, et al.. Myeloperoxidase is a key regulator of oxidative stress mediated apoptosis in myeloid leukemic cells. Clin Cancer Res 2007; 13: 5436–5445.
  • Kong Q, Beel JA, Lillehei KO. A threshold concept for cancer therapy. Med Hypotheses 2000; 55: 29–35.
  • Haddad JJ. Redox and oxidant-mediated regulation of apoptosis signaling pathways: immuno-pharmaco-redox conception of oxidative siege versus cell death commitment. Int Immunopharmacol 2004; 4: 475–493.
  • Ozben T. Oxidative stress and apoptosis: impact on cancer therapy. J Pharm Sci 2007; 96: 2181–2196.

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