1,121
Views
14
CrossRef citations to date
0
Altmetric
Original Article

shRNA-Mediated BAALC knockdown affects proliferation and apoptosis in human acute myeloid leukemia cells

, , , , , & show all
Pages 35-40 | Published online: 12 Nov 2013

References

  • Estey E, Döhner H. Acute myeloid leukaemia.Lancet. 2006;368:1894–907.
  • Smith M, Barnett M, Bassan R, Gatta G, Tondini C, Kern W. Adult acute myeloid leukaemia. Crit Rev Oncol Hematol. 2004;50:197–222.
  • Ferrara F. Unanswered questions in acute myeloid leukaemia. Lancet Oncol. 2004;5:443–50.
  • Avivi I, Rowe JM. Prognostic factors in acute myeloid leukemia. Curr Opin Hematol. 2005;12:62–7.
  • Marcucci G, Haferlach T, Döhner H. Molecular genetics of adult acute myeloid leukemia: prognostic and therapeutic implications. J Clin Oncol. 2011 Feb 10;29(5):475–86.
  • Marchesi F, Annibali O, Cerchiara E, Tirindelli MC, Avvisati G. Cytogenetic abnormalities in adult non-promyelocytic acute myeloid leukemia: A concise review. Crit Rev Oncol Hematol. 2011;80(3):331–46.
  • Mrózek K, Heerema NA, Bloomfield CD. Cytogenetics in acute leukemia. Blood Rev. 2004;18:115–36.
  • Zheng J, Wang X, Hu Y, Yang J, Liu J, He Y, et al.. A correlation study of immunophenotypic, cytogenetic, and clinical features of 180 AML patients in China. Cytometry B Clin Cytom. 2008;74:25–9.
  • Farag SS, Ruppert AS, Mrózek K, Mayer RJ, Stone RM, Carroll AJ, et al.. Outcome of induction and postremission therapy in younger adults with acute myeloid leukemia with normal karyotype: a cancer and leukemia group B study. J Clin Oncol. 2005;23:482–93.
  • Dunna NR, Rajappa S, Digumarti R, Vure S, Kagita S, Damineni S, et al.. Fms Like Tyrosine Kinase (FLT3) and Nucleophosmin 1 (NPM1) mutations in de novo normal karyotype acute myeloid leukemia (AML). Asian Pac J Cancer Prev. 2010;11:1811–6.
  • Damm F, Oberacker T, Thol F, Surdziel E, Wagner K, Chaturvedi A, et al.. Prognostic importance of histone methyltransferase MLL5 expression in acute myeloid leukemia. J Clin Oncol. 2011;29:682–9.
  • Taskesen E, Bullinger L, Corbacioglu A, Sanders MA, Erpelinck CA, Wouters BJ, et al.. Prognostic impact, concurrent genetic mutations, and gene expression features of AML with CEBPA mutations in a cohort of 1182 cytogenetically normal AML patients: further evidence for CEBPA double mutant AML as a distinctive disease entity. Blood. 2011;117:2469–75.
  • Baldus CD, Tanner SM, Kusewitt DF, Chapelle A. BAALC, a novel marker of human hematopoietic progenitor cells. Exp Hematol. 2003;31(11):1051–6.
  • Tanner SM, Austin JL, Leone G, Rush LJ, Plass C, Heinonen K, et al.. BAALC, the human member of a novel mammalian neuroectoderm gene lineage, is implicated in hematopoiesis and acute leukemia. Proc Natl Acad Sci U S A. 2001,98(24):13901–6.
  • Langer C, Radmacher MD, Ruppert AS, Whitman SP, Paschka P, Mrózek K, et al.. High BAALC expression associates with other molecular prognostic markers, poor outcome, and a distinct gene-expression signature in cytogenetically normal patients younger than 60 years with acute myeloid leukemia: a Cancer and Leukemia Group B (CALGB) study. Blood. 2008;111(11):5371–9.
  • Eid MA, Attia M, Abdou S, El-Shazly SF, Elahwal L, Farrag W, et al.. BAALC and ERG expression in acute myeloid leukemia with normal karyotype: impact on prognosis. Int J Lab Hematol. 2010;32(2):197–205.
  • Schwind S, Marcucci G, Maharry K, Radmacher MD, Mrózek K, Holland KB, et al.. BAALC and ERG expression levels are associated with outcome and distinct gene and microRNA expression profiles in older patients with de novo cytogenetically normal acute myeloid leukemia: a Cancer and Leukemia Group B study. Blood. 2010;116(25):5660–9.
  • Santamaría C, Chillón MC, García-Sanz R, Pérez C, Caballero MD, Mateos MV, et al.. BAALC is an important predictor of refractoriness to chemotherapy and poor survival in intermediate-risk acute myeloid leukemia (AML). Ann Hematol. 2010;89(5):453–8.
  • Kurreck J. RNA interference: From basic research to therapeutic applications. Angew Chem Int Ed Engl. 2009;48(8):1378–98.
  • Angaji SA, Hedayati SS, Poor RH, Madani S, Poor SS, Panahi S. Application of RNA interference in treating human diseases. J Genet. 2010;89:527–37.
  • Heesch S, Schlee C, Neumann M, Stroux A, Kühnl A, Schwartz S, et al.. BAALC-associated gene expression profiles define IGFBP7 as a novel molecular marker in acute leukemia. Leukemia. 2010;24:1429–36.
  • Zaidi SZ, Owaidah T, Al Sharif F, Ahmed SY, Chaudhri N, Aljurf M. The challenge of risk stratification in acute myeloid leukemia with normal karyotype. Hematol Oncol Stem Cell Ther. 2008;1:141–58.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.