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Letters

Suppression of Crucial Information in the IARC Evaluation of DEHP

Pages 84-85 | Published online: 20 Nov 2013

References

  • IARC. Di (2-e thylhexyl) ph thalate. In:'ARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol. 77. Lyon, France: IARC, 2000: 41-148.
  • Melnick RL. The IARC evaluation of di (2-ethylhexyl) phthalate (DEHP): a flawed decision based on an untested hypothesis. Int J Occup Environ Health. 2002; 8: 284–6.
  • Parzefall W, Berger W, Kainzbauer E, Teufelhofer 0, Schulte-Hermann R, Thurman RG. Peroxisome proliferators do not increase DNA synthesis in puri-fied rat hepatocytes. Carcinogenesis. 2001; 22: 519–23.
  • Rose ML, Rivera CA, Bradford BU, Graves LM, Cattley RC, Schoonhoven R, Swenberg JA, Thurman RG. Kupffer cell oxidant production is central to the mechanism of peroxisome proliferators. Carcinogenesis. 1999; 20: 27–33.
  • Rose ML, Germolec D, Arteel GE, Schoonhoven R, Thurman RG. Dietary glycine prevents increases in hepatocyte proliferation caused by the peroxisome proliferator WY-14,643. Chem Res Toxi-col. 1997; 10: 1198-204.
  • Rose ML, Cattley RC, Dunn C, Wong V, Li X, Thurman RG. Dietary glycine pre-vents the development of liver tumors caused by the peroxisome proliferator Wy-14,643. Carcinogenesis. 1999; 20: 2075-81.
  • Rose ML, Rusyn I, Bojes HK, Belyea J, Cattley RC, Thurman RG. Role of Kupf-fer cells and oxidants in signaling perox-isome proliferator-induced hepatocyte proliferation. Mutat Res. 2000; 448: 179–92
  • Peters JM, Rusyn I, Rose ML, Gonzalez FJ, Thurman RG. Peroxisome prolifera-tor-activated receptor a is restricted to hepatic parenchymal cells, not Kupffer cells: implications for the mechanism of action of peroxisome proliferators in hepatocarcinogenesis. Carcinogenesis. 2000; 21: 823–6.

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