Some Peculiarities of Pulmonary Clearance Mechanisms in Rats after Intratracheal Instillation of Magnetite (Fe₃O₄) Suspensions with Different Particle Sizes in the Nanometer and Micrometer Ranges: Are We Defenseless against Nanoparticles?

References

• Velichkovski BT, Katsnelson BA. Etiology and pathogenesis of silicosis. Moscow: Medizina Publishing House; 1964. (Russian)
   Google Scholar
• Oberdörster G, Oberdörster E, Oberdörster J. Nanotoxicology: An emerging discipline evolving from studied of ultrafine particles. Environ Health Persp. 2005; 113: 823–839.
   PubMed Web of Science ®Google Scholar
• Onishthchenko GG, Archakov Al, Bessonov VV, Bokitko BG, Hinzburg AL, et al. Methodological approaches to the assessment of safety of nano-materials. In: Rakhmanin Y uA, ed. Methodological problems of research in and assessment of bio-and nanotechnologies (nano-scale waves, particles, structures, processes, biologic objects) in the human ecology and environmental protection. Moscow: Sysin's Institute; 2007. (Russian)
   Google Scholar
• Li N, Xia T, Nel AE. The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. Free Rad Biol Med. 2008; 44: 1689–1699.
   PubMed Web of Science ®Google Scholar
• Donaldson K, Stone V, Tran CK, Kreyling W, Borm PJ. Nan-otoxicology (editorial). Occup Environ Med. 2004; 61: 727–728.
   PubMed Web of Science ®Google Scholar
• Grassian VH, O'Shaughnessy PT, Adamcakova-Dodd A, Pettibone JM, Thorne PS. Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm. Environ Health Perspect. 2007; 115: 397–402.
   PubMed Web of Science ®Google Scholar
• Li N, Sioutas C, Cho A, Schmits D, Misra Ch, Sempf J, et al. Ultraflne particulate pollutants induce oxidative stress and mitochondrial damage. Environ Health Perspect. 2003;111 (4): 455–460.
   PubMed Web of Science ®Google Scholar
• Kilburn KH. Alveolar clearance of particles. A bullfrog lung model. Arch Environ Health. 1969; 18: 556–563.
   PubMed Web of Science ®Google Scholar
• Bastus NG, Casals E, Socorro V-C, Puntes V. Reactivity of engineered inorganic nanoparticles and carbon nanostructures in biological media. Nanotoxicol. 2008; 2: 99–112.
   Web of Science ®Google Scholar
• Warheit DB, Reed XL, Sayes CM. A role fore surface reactivity in TiO2 and quartzrelated nanoparticle pulmonary toxicity. Nanotoxicol. 2009; 3: 181–187.
   Web of Science ®Google Scholar
• Kreyling WG, Semmler M, Erbe P, Mayer P, Takenaka S, Schulz H, Oberdörster G, Ziesenis A. Translocation of ultrafine insoluble iridium particles from lung epthelium to extrapulmonary organs is size dependent but very low. J Toxicol Environ Health. 2002;65A:1513–1530.
   Web of Science ®Google Scholar
• Semmler M, Seitz J, Erbe E, Mayer P, Heyder J, Oberdörster G, Kreylig WG. Long-term clearance kinetics of inhaled ultrafine insoluble iridium particles from the rat lung, including transient translocation into secondary organs. Inhal Toxicol. 2004; 16: 453–459.
   PubMed Web of Science ®Google Scholar
• Renwick L, Brown D, Clouter K and Donaldson K. Increased inflammation and altered macrophage chemotactic responses caused by two ultrafine particle types. Occup Environ Med. 2004; 61: 442–447.
   Google Scholar
• Zhu MT, Feng WY, Wang B, Wang TC, Gu YQ Wang Y, Ouyang H, Zhao YL, Chai LI. Comparative study of pulmonary responses to nano and submicron ferric oxide in rats. Toxicol. 2008; 247: 102–111.
   Google Scholar
• Monteiller C, Tran L, MacNee W, Faux S, Jones A, Miller B, Donaldson K. The pro-inflammatory effects of low-toxicity low-solubility particles, nanoparticles and fine particles, on epithelial cells in vitro: the role of surface area. Occup and Environ Med. 2007; 64 (9): 609–615.
   PubMed Web of Science ®Google Scholar
• Warheit DB, Webb TR, Colvin VL, Reed XL, Sayes CM. Pulmonary bioassay studies with nanoscale and fine-quartz particles in rats: Toxicity is not dependent upon particle size but on surface characteristics. Toxicol Sci. 2007; 95: 270–280.
   PubMed Web of Science ®Google Scholar
• Gubin SP, Koksharov YA, Homutov GB, Yurkov GY. Magnetic nanoparticles: Generating methods, structure, and properties. Uspekhi Chimii. 2005; 74: 539–574. (Russian)
   Web of Science ®Google Scholar
• Zhang PC, Bai C, Huang YM, Zhao H, Fang Y, Wang NX, Li Q. Atomic force microscopy study of fine structures of the entire surface of red blood cells. Scanning Microscopy. 1995;9 (4): 981.
   PubMedGoogle Scholar
• Zaitsev BN, Durymanov AG, Generalov VM. Atomic force microscopy of the interaction of erythrocyte membrane and virus particles. Proc Int Workshop: “Scanning Probe Microscopy.” Nizhny Novgorod, Russia; 2002.
   Google Scholar
• Lomonosov AM, Egorov SN, Gallyamov MO, Yaminsky W. AFM of bacterial cells subjected to different factors. Phys Low-Dim Struct. 2003;3/4:125.
   Google Scholar
• Bolshakova AV, Kiselyova OI, Yaminsky W. Microbial surfaces investigated using atomic force microscopy. Biotechnol Progress. 2004; 20: 1615.
   PubMed Web of Science ®Google Scholar
• Dubrovin EV, Voloshin AG, Kraevsky SV, Ignatyuk TE, Abram-chuk SS, Yaminsky W, Ignatov SG. Atomic force microscopy investigation of phage infection of bacteria. Langmuir. 2008; 24: 13068.
   PubMed Web of Science ®Google Scholar
• Lurje YY Standardized methods for analyzing waters. Moscow: Khimiya Publising House; 1973. (Russian).
   Google Scholar
• Urbach VYu. Biometric methods (Statistical treatment of experimental data in biology, agriculture, and medicine). 2nd ed. Moscow: Nauka Publishing House; 1964. (Russian)
   Google Scholar
• Xie J, Xu Ch, Hou Y, Young XL, Wang SX, Pourmond N, Sun Sh. Linking hydrophilic macromolecules to monodisperse magnetite (Fe304) nanoparticled via trichloro-S-triazine. Chem Mater. 2006; 18: 5401-5403.
   Google Scholar
• Xie J, Chen K, Lee H-Y, Xu Ch, Hsu AP, Peng S, Chen X, Sun Ah. Ultra small c(RgDyK)-coated Fe304 nanoparticles and the,ir specific targeting to integrin 5.17B-rich tumor cells. J Am Chem Soc. 2008; 130: 7452–7453.
   Google Scholar
• Cho WS, Cho M, Kim SR, Lee JY, Han BS, Park SN, Yu MK, Jon S, Leong J. Pulmonary toxicity and kinetic study of Cy5,5-conju-gated superparamagnetic iron oxide nanoparticles by optical imaging. Toxicol Appl Pharmacol. 2009; 239: 106–115.
   PubMed Web of Science ®Google Scholar
• Mahmoudi M, Simchi A, Imani M, Milani AS and Stroeve P. An in vitro study of bare and poly(ethylene glycol)-co-fumarate-coated supermagnetic iron oxide nanoparticles: a new toxicity identification procedure. Nanotechnol. 2009 June; 20 (22): 225104.
   PubMed Web of Science ®Google Scholar
• Sager TM, Porter DW, Robinson VA, Lindsley WG, Schwegler-Berry VA, Castranova V. Improved method to disperse nanopar-tides in vitro and in vivo investigation of toxicity. Nanotoxicol. 2007; 1: 118–129.
   Web of Science ®Google Scholar
• Katsnelson BA,Privalova U. Recruitment of pagocytizing cells into the respiratory tract as a response to the cytotoxic action of deposited particles. Environ Health Perspect. 1984; 55: 313–325.
   PubMed Web of Science ®Google Scholar
• Privalova LI, Katsnelson BA, Osipenko AB, Yushkov BH, Babushkina LG. Response of a phagocyte cell system to prod-ucts of macrophage breakdown as a probable mechanism of alveolar phagocytosis adaptation to deposition of particles of different cytotoxicity. Environ Health Perspect. 1980; 35: 205–218.
   PubMed Web of Science ®Google Scholar
• Privalova LI, Katsnelson BA and Yelnichnykh LN. Some peculiarities of the pulmonary phagocytotic response, dust kinetics, and silicosis development during long term exposure of rats to high quartz levels. Brit J Ind Med. 1987; 44: 228–235.
   PubMedGoogle Scholar
• Privalova LI, Katsnelson BA, Sharapova NY, Kislitsina NS. On the relationship between activation and the breakdown of macrophages in pathogenesis of silicosis. Medic Lavoro. 1995; 86: 511–521.
   PubMedGoogle Scholar
• Klarisson HL, Gustaffson J, Cronholm P, Möller L. Size-dependent toxicity of metal oxide particles-a comparison between nano and micrometer size. Toxicol Lett. 2009; 188: 112–118.
   PubMed Web of Science ®Google Scholar
• Stoeger T, Reinhard C, Takenaka Sh, Schroeppel A, Karg E, Ritter B, et al. Instillation of six different ultrafine carbon parti-cles indicates a surface area threshold dose for acute lung inflammation in mice. Environ Health Perspect. 2006; 114 (3): 328–333.
   PubMed Web of Science ®Google Scholar
• Katsnelson BA, Konysheva LK, Privalova LY, Morosova M. Development of a multicompartmental model of the kinetics of quartz dust in the pulmonary region of the lung during chronic inhalation exposure of rats. Brit J Ind Med. 1992; 49: 172–181.
   PubMedGoogle Scholar
• Katsnelson BA, Konyscheva LK, Sharapova NYE, Privalova LI. Prediction of the comparative intensity of pneumoconiotic changes caused by chronic inhalation exposure to dusts of different cytotoxicity by means of a mathematical model. Occup Environ Med. 1994; 51: 173–180.
   PubMed Web of Science ®Google Scholar
• Katsnelson BA, Konysheva LK, Privalova LY, Sharapova NY Quartz dust retention in rat lungs under chronic exposure simulated by a multicompartmental model: Further evidence of the key role of the cytotoxicity of quartz particles. Inhalat Toxicol. 1997; 9: 703–715.
   Web of Science ®Google Scholar
• Zhu MT, Feng WY, Wang Y, Wang B, Wang M, Ouyang H, et al. Particokinetics and extrapulmonary translocation of intratracheally instilled ferric oxide nanoparticles in rats and the potential health risk assessment. Toxicol Sciences. 2009; 107 (2): 342–351.
   PubMed Web of Science ®Google Scholar
• Petin LM. Data for establishing the maximal allowable concentration of silicacontaining condensation aerosols. Gigiyena Truda. 1978; 6: 28–33. (Russian)
   PubMedGoogle Scholar
• Podgayko GA, Katsnelson BA, Lemyasev MF, Solomina SN, Saitov VA, Russjayeva LV. New data for assessment of the silicosis risks due to industrial aerosols based on a colloidal solution of silicic acid. In: Domnin SG and Katsnelson BA, eds. Occupational diseases due to dusts. Issue 7. Moscow: Erisman's Institute; 1982. (Russian).
   Google Scholar
• Katsnelson BA, Privalova LI, Kislitsina NS, Podgaiko GA. Correlation between cytotoxicity and fibrogenicity of silicosis-inducing dusts. Med Lavoro. 1984; 75: 450–462.
   PubMedGoogle Scholar
• Katsnelson BA, Alekseyeva OG, Privalova LI, Polzik EV. Pneumoconioses: The pathogenesis and biological prophylaxis. Eka-terinburg: The Urals Branch of the RAS; 1995 (Russian)
   Google Scholar