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Redox Report
Communications in Free Radical Research
Volume 5, 2000 - Issue 2-3
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Characterisation of kynurenine pathway metabolism in human astrocytes and implications in neuropathogenesis

G.J. GuilleminCentre for Immunology St Vincent's Hospital, Sydney , New South Wales, Australia
,
D.G. SmithCentre for Immunology St Vincent's Hospital, Sydney , New South Wales, Australia
,
S.J. KerrCentre for Immunology St Vincent's Hospital, Sydney , New South Wales, Australia
,
G.A. SmytheThe Ray Williams Biomedical Mass Spectrometry Facility University of New South Wales , Sydney, New South Wales, Australia
,
V. KapoorSchool of Physiology and Pharmacology Faculty of Medicine, University of New South Wales , Sydney, New South Wales, Australia
,
P.J. ArmatiSchool of Biological Sciences University of Sydney, Sydney , New South Wales, Australia
&
B.J. BrewDepartments of Neurology and HIV Medicine St Vincent's Hospital, Sydney , New South Wales, Australia
 show all
Pages 108-111 | Published online: 19 Jul 2013

REFERENCES

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  • Bolting NP. Chemistry and neurochemistry of the kynurenine pathway of tryptophan metabolism. Chem Soc Rev 1995; 24: 401–412.
  • Heyes MP, Chen CY, Major EO, Saito K. Different kynurenine pathway enzymes limit quinolinic acid formation by various human cell types. Biochem J 1997; 326: 351–356.
  • Kerr SJ, Armati PJ, Pemberton LA, Smythe G, Tattam B, Brew BJ. Kynurenine pathway inhibition reduces toxicity of HIV-infected macrophages. Neurology 1997; 49: 1671–1681.
  • Tamburin M, Mostardini M, Benatti L. Kynurenine amino-transferase I (KATI) isoform gene expression in the rat brain: an in situ hybridization study. Neuroreport 1999; 10: 61–65.
  • Guillemin G, Boussin F, Croitoru J, Le Grand R, Dormont D. Obtention and characterization of astrocytes and microglia from adult monkey brains. J Neurosci Res 1997; 49: 576–591.
  • Kerr SJ et al. Kynurenine pathway inhibition reduces toxicity of HIV-infected macrophages. Neurology 1997; 49: 1671–1681.
  • Kapoor V, Kapoor R, Chalmers J. Kynurenic acid, an endogenous glutamate antagonist, in SHR and WKY rats: possible role in central blood pressure regulation. Clin Exp Pharmacol Physiol 1994; 21: 891–896.
  • Brew BJ, Wesselingh SL, Gonzales M, Heyes MP, Price RW. How HIV leads to neurological disease. Med J Aust 1996; 164: 233–234.

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