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Redox Report
Communications in Free Radical Research
Volume 5, 2000 - Issue 2-3
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Miscellany

Lysosomotropic detergents induce time- and dose-dependent apoptosis/necrosis in cultured cells

Pages 87-88 | Published online: 19 Jul 2013

REFERENCES

  • Brunk UT, Zhang H, Roberg K, (Anger K. Lethal hydrogen peroxide toxicity involves lysosomal iron-catalyzed reactions with membrane damage. Redox Report 1995; 1: 267–277.
  • Brunk UT, Svensson I. Oxidative stress, growth-factor starvation, and FAS-activation may all cause apoptosis through lysosomal leak. Redox Report 1999; 4: 3–11.
  • Firestone RA, Pisano JM, Bonney RJ. Lysosomotropic agents I. Synthesis and cytotoxic action of lysosomotropic detergents. J Med Chem 1979; 22: 1130–1133.
  • de Duve C, de Barsy T, Poole B, Trouet A, Tulkens P, Van Hoof F. Commentary: lysosomotropic agents. Biochem Pharmacol 1974; 23: 2495–2513.
  • Vancompernolle K, Van Herreweghe F, Pynaert G et al. Atractyloside-induced release of cathepsin B, a protease with caspase-processing activity. FEBS Lett 1998; 438: 150–158.
  • Ishisaka R, Utsumi T, Yabuki M et al. Activation of caspase-3-like protease by digitonin-treated lysosomes. FEBS Lett 1998; 435: 233–236.
  • Brunk UT, Ericsson JLE. Cytochemical evidences for leakage of acid phosphatase through ultrastructurally intact lysosomal membranes. Histochem J1972; 4: 479-491.
  • Nilsson E, Ghassemifar R, Brunk UT. Lysosomal heterogeneity within and between cells with respect to resistance to oxidative stress. Histochem J1997; 29: 857-865.
  • de Duve C. The lysosome in retrospect. In: Dingle JT, Fell HB. (eds) Lysosomes in Biology and Pathology, vol I. Amsterdam: North-Holland, 1969; 3-40.

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