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Redox Report
Communications in Free Radical Research
Volume 6, 2001 - Issue 3
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Miscellany

Relative susceptibilities of mitochondrial and nuclear DNA to damage induced by hydrogen peroxide in two mouse germ cell lines

D.E. SawyerDiscipline of Biological Sciences The University of Newcastle, Callaghan , New South Wales, Australia
,
S.D. RomanDiscipline of Biological Sciences The University of Newcastle, Callaghan , New South Wales, Australia
&
R.J. AitkenDiscipline of Biological Sciences The University of Newcastle, Callaghan , New South Wales, Australia
Pages 182-184 | Published online: 19 Jul 2013

  • Ames BN, Shigenaga MK, Hagen TM. Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci USA 1993; 90: 7915–7922.
  • Griveau JF, Le Lannon D. Reactive oxygen species and human spermatozoa: physiology and pathology. Int J Androl 1997; 20: 61–69.
  • Aitken RJ. The human spermatozoon - a cell in crisis? J Reprod Fertil 1999; 115: 1–7.
  • Fraga CG, Motchnik PA, Wyrobeck AJ, Rempel DM, Ames BN. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res 1996; 351: 199–203.
  • Wells PG, Kim PM, Laposa RR, Nicol CJ, Pannan T, Winn LM. Oxidative damage in chemical teratogenesis. Mutat Res 1997; 396: 65–78.
  • Ishihara M, Itoh M, Mayamoto K et al. Spermatogenic disturbance induced by di-(2-ethylhexyl) phthalate is significantly prevented by treatment with antioxidant vitamins in the rat. Int J Androl 2000; 23: 85–94.
  • Wellejus A, Poulsen HE, Loft S. Iron-induced oxidative DNA damage in rat sperm cells in vivo and in vitro. Free Radic Res 2000; 32: 75-83.
  • Fraga CG, Motchnik PA, Shigenaga MK, Helbock HJ, Jacob RA, Ames BN. Ascorbic acid protects against endogenous oxidative DNA damage in human sperm. Proc Natl Acad Sci USA 1991; 88: 11003–11006.
  • Oteiza PI, Olin KL, Fraga CG, Keen CL. Zinc deficiency causes oxidative damage to proteins, lipids and DNA in rat testes. J Nutr 1995; 125: 823–829.
  • Ochsendorf FR. Infection and reactive oxygen species. Ardrologia 1998; 30 (Suppl 1): 81-86.
  • Comhaire FH, Mahmoud AM, Depuydt CE, Zalata AA, Cluistophe AB. Mechanisms and effects of male genital tract infection on sperm quality and fertilizing potential: the anthologist's viewpoint. Hum Reprod Update 1999; 5: 393–398.
  • Hoffman MC, Narisawa S, Hess RA, Milian JL. Immortalisation of germ cells and somatic testicular cells using the SV40 large T antigen. Exp Cell Res 1992; 201: 417–435.
  • Hoffman MC, Hess RA, Goldberg I, Millan JL. Immortalised germ cells undergo meiosis in vitro. Proc Natl Acad Sci USA 1994; 91: 5533–5537.
  • Yakes FM, Van Houten B. Mitochondrial DNA damage is more extensive and persists longer than nuclear DNA damage in human cells following oxidative stress. Proc Natl Acad Sci USA 1997; 94: 514–519.
  • Ayala-Torres S, Chen Y, Svoboda T, Rosenblatt J, Van Houten B. Analysis of gene-specific DNA damage and repair using quantitative polymerase chain reaction. Methods 2000; 22: 135–147.
  • Drouin R, Gao S, Holmquist GP. Agarose gel electrophoresis for DNA damage analysis. In: Pfeifer G. (ed) Technologies for Detection of DNA Damage and Mutations. New York: Plenum, 1996; 37–43.
  • Van Houten B, Chandrasekhar D, Huang W, Katz E Mapping DNA lesions at the gene level using quantitative PCR methodology. Amplifications (The Perkin-Elmer Corp.) 1993; 10: 10–17.
  • McCullough AK, Dodson ML, Lloyd RS. Initiation of base excision repair: glycosylase mechanisms and structures. Annu Rev Biochem 1999; 68: 255–285.
  • Richter C, Park JW, Ames B. Normal oxidative damage to mitochondrial and nuclear DNA is extensive. Proc Natl Acad Sci USA 1988; 85: 6465–6467.
  • Dfiggers WJ, LeDoux SP, Wilson GL. Repair of oxidative damage within the mitochondrial DNA of RINr 38 cells. J Biol Chem 1993; 268: 22042–22045.

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