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Redox Report
Communications in Free Radical Research
Volume 6, 2001 - Issue 3
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Research Articles

The protective action of melatonin on indomethacin-induced gastric and testicular oxidative stress in rats

A.I. OthmanZoology Department Faculty of Science, University of Mansoura, Mansoura , Egypt
,
M.A. El-MissiryZoology Department Faculty of Science, University of Mansoura, Mansoura , Egypt
&
M.A. AmerZoology Department Faculty of Science, University of Mansoura, Mansoura , Egypt
Pages 173-177 | Published online: 02 Dec 2013

  • Reiter RJ. Interactions of the pineal hormone melatonin with oxygen-centred free radicals: a brief review. Braz J Med Biol Res 1993; 26: 1141–1155.
  • Kaya H, Oral B, Ozguner F, Tahan V, Babar Y, Delibas N. The effect of melatonin application on lipid peroxidation during cyclophosphamide therapy in female rats. Zentralbl Gynakol 1999; 211: 499–502.
  • Qi W, Tan DX, Reiter RJ et al. Melatonin reduces lipid peroxidation and tissue edema in cerulein-induced acute pancreatitis in rats. Dig Dis Sci 1999; 44: 2257–2262.
  • Tesoriere L, D'Arpa D, Conti S, Giaccone V, Pintaudi AM, Livrea MA. Melatonin protects human red blood cells from oxidative haemolysis: new insights into the radical-scavenging activity. J Pineal Res 1999; 27: 95–105.
  • Badr FM, El-Habit OH, Harraz MM. Radioprotective effect of melatonin assessed by measuring chromosomal damage in mitotic and meiotic cells. Mutat Res 1999; 444: 367–372.
  • El-Missiry MA. Prophylactic effect of melatonin on lead-induced inhibition of heme biosynthesis and deterioration of antioxidant system in male rats. J Biochem Mol Toxicol 2000; 14: 57–61.
  • El-Missiry MA, Abdel-Aziz AF. Influence of melatonin on proliferation and antioxidant system in Ehrlich ascites carcinoma cells. Cancer Lett 2000; 151: 119–125.
  • Reiter RJ, Cameiro RC, Oh CS. Melatonin in relation to cellular anti-oxidative defence mechanisms. Horn Metab Res 1997; 29: 363–372.
  • Zhang H, Squadrito GL, Uppu R, Pryor WA. Reaction of peroxynitrite with melatonin: a mechanistic study. Chem Res Toxicol 1999; 12: 526-534.
  • Kato K, Murai I, Asai Set al. Central effect of melatonin against stress-induced gastric ulcers in rats. Neuroreport 1997; 8: 2305–2309.
  • De la Lastra AC, Motilva V, Martin MJ et al. Protective effect of melatonin on indomethacin-induced gastric injury in rats. J Pineal Res 1999; 26: 101–107.
  • Naito Y, Yoshikawa T, Yoshida N, Kondo M. Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury. Dig Dis Sci 1998; 43: 305–345.
  • Sagar V, Ahamed RN. Gastric mucosal cellular changes induced by indomethacin (NSAID) in male albino rats. Indian J Exp Biol 1999; 37: 365–369.
  • Yoshikawa T, Naito Y, Kishi A et al. Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin in rats. Gut 1993; 34: 732–737.
  • Naito Y, Yoshikawa T, Matsuyama K et al. Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. Free Radic Biol Med 1998; 24: 494–502.
  • Takeuchi K, Ueshima K, Hironaka Y, Fujioka Y, Matsumoto J, Okabe S. Oxygen free radicals and lipid peroxidation in the pathogenesis of gastric mucosal lesions induced by indomethacin in rats. Relation to gastric hypermotility. Digestion 1991; 49: 175–184.
  • Yoshikawa T, Minamiyama Y, Ichikawa H, Takahashi S, Naito Y, Kondo M. Role of lipid peroxidation and antioxidants in gastric mucosal injury induced by the hypoxanthine-xanthine oxidase system in rats. Free Radic Biol Med 1997; 23: 243–250.
  • Savran B, Gorgun CZ, Zengil H. Circadian reactivity rhythm of rat gastric mucosa to restraint-cold stress and indomethacin: temporal variation in the protective effect of iloprost. Chronobiol Int 1997; 14: 575–583.
  • Ito M, Suzuki Y, Ishihara M, Suzuki Y. Anti-ulcer effects of antioxidants: effect of probucol. Eur J Pharmacol 1998; 354: 189–196.
  • Konturek PC, Konturek SJ, Majka J, Zembala M, Hahn EG. Melatonin affords protection against gastric lesions induced by ischemia-reperfusion possibly due to its antioxidant and mucosal microcirculatory effects. Eur J Pharmacol 1997; 322: 73–77.
  • Ohkawa H, Ohishi N, Yagi K. Assay for lipid peroxidation in animal tissues by thiobarbituric acid reaction. Anal Biochem 1979; 95: 351–358.
  • Moss DW, Hendersen AR. Kachmar JR. Enzyme. In: Tietz NW. (ed) Textbook of Clinical Chemistry. Philadelphia, PA: WB Saunders, 1986; 619–663.
  • Nishikimi M, Appaji N, Yagi K. The occurrence of superoxide anion in the reaction of reduced phenazine methosulfate and molecular oxygen. Biochem Biophys Res Commun 1972; 46: 849–854.
  • Bock PP, Kramer R, Pavelka M. A simple assay for catalase determination. Cell Biol Monogr 1980; 7: 44–74.
  • Beutler E. Red Cell Metabolism: A Manual of Biochemical Methods, 2nd edn. New York: Grune and Stratton, 1982; 66-72.
  • Naito Y, Yoshikawa T, Matsuyama K, Nishimura S, Yagi N, Kondo M. Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. Dig Dis Sci 1995; 40: 2019–2021.
  • Halliwell B. Free radicals, antioxidants and human disease: Curiosity, cause or consequence? Lancet 1994; 344: 721–724.
  • Wallace J, Kenan CM, Granger DN. Gastric ulceration induced by non steroidal anti-inflammatory drugs is a neutrophil-dependant process. Am J Physiol 1990; 259: G462–G467.
  • Wallace J, Arfors KC, McKnight GU. A monoclonal antibody against the CD18 leukocytes adhesion molecule prevents indomethacin-induced gastric damage in the rabbit. Gastroenterology 1991; 100: 878–883.
  • Tanaka J, Yuda Y. Lipid peroxidation in gastric mucosal lesions induced by indomethacin in rat. Biol Phann Bull 1996; 19:716–720.
  • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radic Biol Med 1991; 4: 81–128.
  • Melchiorri D, Sewerynek E, Reiter RJ, Ortiz GG, Poeggeler B, Nistico G. Suppressive effect of melatonin administration on ethanol-induced gastroduodenal injury in rats in vivo. Br J Pharmacol 1997; 121: 264–270.
  • Esterbauer H, Dieber-Rotheneder M, Striegl G, Waeg G. Role of vitamin E in preventing the oxidation of low density lipoprotein. Am J Clin Nutr 1991; 53 (Suppl. 1): 314S-321S.
  • Fridovich I. Superoxide dismutases: an adaptation to a paramagnetic gas. J Biol Chem 1989; 264: 19328–19333.
  • Cadenas E. Mechanism of oxygen activation and reactive oxygen species. In: Ahmed S. (ed) Oxidative Stress and Antioxidant Defences in Biology. London: Chapman and Hall, 1995; 1–61.
  • Patel RE, McAndrew J, Sellak H et al. Biological aspects of reactive nitrogen series. Biochim Biophys Acta 1999; 1411: 385–400.
  • Pryor W, Squadrito B. The chemistry of peroxynitrite: a product from the reaction of nitric oxide with superoxide. Am J Physiol 1995; 268: L699–L722.
  • Reiter RJ, Tan DX, Cabrera J, D'Arpa D. A review of the evidence supporting melatonin's role as an antioxidant. J Pineal Res 1995; 18: 1–11.
  • Reiter RJ, Tan DX, Cabrera J et al. The oxidant/antioxidant network: role of melatonin. Biol Signal Recept 1999; 8: 56–63.
  • Pozo D, Reiter RJ, Calvo JR, Guerrero JM. Inhibition of cerebellar nitric oxide synthase and cyclic GMP production by melatonin via complex formation with calmodulin. J Cell Biochem 1997; 65: 430–432.
  • Reiter RJ, Tan DX, Qi WB. Suppression of oxygen toxicity by melatonin. Chung Kuo Yao Li Hsueh Pao 1998; 19: 575–581.
  • Okatani Y, Wakatsuki A, Kaneda C. Melatonin increases activities of glutathione peroxidase and superoxide dismutase in foetal rat brain. J Pineal Res 2000; 28: 89–96.
  • Kato K, Murai I, Asai S et al. Protective role of melatonin and the pineal gland in modulating water immersion restraint stress ulcer in rats. J Clin Gastroenterol 1998; 27: S110–S115.
  • De La Lastra CA, Cabeza J, Motilva V, Martin MJ. Melatonin protects against gastric ischemia-reperfusion injury in rats. J Pineal Res 1997; 23: 47–52.
  • Li XJ, Gu J, Pan BS, Sun FY. Effect of melatonin on production of hydroxyl radical and lactate dehydrogenase during hypoxia in rat cortical slices. Chung Kuo Yao Li Hsueh Pao 1999; 20: 201–205.
  • Bandyopadhyay D, Biswas K, Bandyopadhyay U, Reiter RJ, Banerjee RIC. Melatonin protects against stress-induced lesions by scavenging the hydroxyl radical. J Pineal Res 2000; 29: 143–151.
  • Limson J, Nyokong T, Daya S. The interaction of melatonin and its precursors with aluminium, cadmium, copper, iron, lead and zinc: an absorptive voltametric study. J Pineal Res 1998; 24: 15–21.

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