- Esterbauer H, Gebicki J, Puhl H, Jiirgens G. The role of lipid peroxidation and antioxidants in oxidative modification of LDL. Free Radic Biol Med 1992; 13: 341–390.
- Katsura M, Forster LA, Ferns GAA, Anggard EE. Oxidative modification of low-density lipoprotein by human polymorphonuclear leucocytes to a form recognised by the lipoprotein scavenger pathway. Biochim Biophys Acta 1994; 1213:231–237.
- Halliwell B. Oxidation of low-density lipoproteins: questions of initiation, propagation, and the effect of antioxidants. Am J Clin Nutr 1995;61: 670S-677S.
- Heinecke JW. Mechanisms of oxidative damage of low density lipoprotein in human atherosclerosis. Curr Opin Lipid 1997; 8: 268–274.
- Hazen SL, Hsu FF, Mueller DM, Crowley JR, Heinecke JW. 3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima. J Clin Invest 1997; 99: 2075–2081.
- Savenkova MI, Mueller DM, Heinecke JW. Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for initiation of lipid peroxidation in low density lipoprotein. J Biol Chem 1994; 269: 20394–20400.
- Nauseef WM. Myeloperoxidase deficiency. Hematol Oncol Clin North Am 1988; 2: 135–158.
- Chisolm III GM, Hazen SL, Fox PL, Cathcart MK. The oxidation of lipoproteins by monocytes-macrophages. J Biol Chem 1999; 274: 25959–25962.
- Hammer A, Kager G, Dohr G, Rabl H, Ghassempur I, Jtirgens G. Generation, characterization, and histochemical application of monoclonal antibodies selectively recognizing oxidatively modified apoB-containing serum lipoproteins. Arterioscler Thromb Vasc Biol 1995; 15: 704–713.
- Wang X, Greilberger J, Ledinski G, Kager G, Jiirgens G. Binding and uptake of differently oxidized low density lipoprotein in mouse peritoneal macrophages and THP-1 macrophages: involvement of negative charges as well as oxidation-specific epitopes. J Cell Biochem 2001; 81: 557–569.
- Gerber CE, Kuci S, Zipfel M, Niethammer D, Bruchelt G. Phagocytic activity and oxidative burst of granulocytes in persons with myeloperoxidase deficiency. Eur J Clin Chem Clin Biochem 1996; 34: 901–908.
- Jürgens G, Lang I, Esterbauer H. Modification of human low density lipoprotein by the lipid peroxidation product 4-hydroxynonenal. Biochim Biophys Acta 1986; 875: 103–114.
- Greilberger J, Schmut 0, Jiirgens G. In vitro interactions of oxidatively modified LDL with type 1,11, 111, IV, and V collagen, laminin, fibronectin, and poly-D-lysine. Arterioscler Thromb Vasc Biol 1997; 17: 2721–2728.
- Morel DW, Hessler JR, Chisolm GM. Low density lipoprotein cytotoxicity induced by free radical peroxidation of lipid. J Lipid Res 1983;24: 1070–1076.
- Buss H, Chan TP, Sluis KB, Domigan NM, Winterbourn CC. Protein carbonyl measurement by sensitive ELISA method. Free Radic Biol Med 1997; 23: 361–366.
- Levine RL, Williams JA, Stadtman ER, Shacter E. Carbonyl assays for the determination of oxidatively modified proteins. Methods Enzymol 1994; 233: 346–357.
- Garner B, Jessup W. Cell-mediated oxidation of low-density lipoprotein: the elusive mechanism(s). Redox Rep 1996; 2: 97–104.
- Ridker PM, Cushman M, Stampfer MJ, Tracy RP, Hennekens CH. Inflammation, aspirin, and the risk of cardiovascular disease in apparently healthy men. N Engl J Med 1997; 336: 973–979.
- van Hinsbergh VW, Scheffer M, Havekes L, Kempen HJ. Role of endothelial cells and their products in the modification of low density lipoproteins. Biochim Biophys Acta 1986; 878: 49–64.
- Wilkins GM, Segal AW, Leake DS. NADPH oxidase is not essential for low density lipoprotein oxidation by human monocyte-derived macrophages. Biochem Biophys Res Commun 1994; 202: 1300–1307.
- Xing XY, Baffic J, Sparrow CP. LDL oxidation by activated monocytes: characterization of the oxidized LDL and requirement for transition metal ions. J Lipid Res 1998; 39: 2201–2208.
- Biemond P, van Eijk HG, Swaak MG, Koster JF. Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. J Clin Invest 1984:73; 1576–1579.
- Abdalla DSP, Campa A, Monteiro HP. Low density lipoprotein oxidation by stimulated neutrophils and ferritin. Atherosclerosis 1992; 97: 149–159.
- Rosen H, Klebanoff SJ. Chemiluminescence and superoxide production by myeloperoxidase-deficient leukocytes. J Clin Invest 1976: 58; 50–60.
- Winterbourn CC, Monteiro HP, Galilee CF. Ferritin dependent lipid peroxidation by stimulated neutrophils: inhibition by myeloperoxidase-derived hypochlorous acid but not by endogenous lactoferrin. Biochim Biophys Acta 1990; 1055: 179–185.
- Garner B, van Reyk D, Dean RT, Jessup W. Direct copper reduction by macrophages. Its role in low density lipoprotein oxidation. J Biol Chem 1997; 272: 6927–6935.
- Britigan BE, Edeker BL. Pseudomonas and neutrophil products modify transferrin and lactoferrin to create conditions that favor hydroxyl radical formation. J Clin Invest 1991; 88: 1092–1102.
- Ehrenwald E, Chisolm GM, Fox PL. Intact human ceruloplasmin oxidatively modifies low density lipoprotein. J Clin Invest 1994; 93: 1493–1501.
- Exner M, Hermann M, Hofbauer R et al. Semicarbazide-sensitive amine oxidase catalyzes endothelial cell-mediated low density lipoprotein oxidation. Cardiovasc Res 2001; 50: 583–588.
- Kirk EA, Dinauer MC, Rosen H, Chait A, Heinecke JW, LeBoef RC. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice. Arterioscler Thromb Vasc Biol 2000; 20: 1529–1535.
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Low-density lipoprotein modification by normal, myeloperoxidase-deficient and NADPH oxidase-deficient granulocytes and the impact of redox active transition metal ions
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