- Hirsch EC, Faucheux B, Damier P, Mouatt-Prigent A, Agid Y. Neuronal vulnerability in Parkinson's disease. J Neural Transm Suppl1997; 50: 79-88.
- Mochizuki H, Goto K, Mori H, Mizuno Y. Histochemical detection of apoptosis in Parkinson's disease. J Neurol Sci 1996; 137: 120–123.
- Anglade P. Vyas S, Javoy-Agid F et al. Apoptosis and autophagy in nigral neurons of patients with Parkinson's disease. Histol Histopathol 1997; 12: 25–31.
- Tompkins MM, Basgall EJ, Zamrini E, Hill WD. Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigra neurons. Am J Pathol 1997; 150: 119–131.
- Halliwall B. Reactive oxygen species and the central nervous system. J Neurochem 1992; 59: 1609–1623.
- Jenner P, Olanow CW. Understanding cell death in Parkinson's disease. Ann Neurol 1998; 44 (Supp. 11): 572-884.
- Ungerstedt U. 6-hydroxydopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 1968; 5: 107–110.
- Jonnson G, Sachs C. Effects of 6-hydroxydopamine on the uptake and storage of noradrenaline in sympathetic adrenergic neurons. Eur J Phannacol 1970; 9: 141–155.
- Ljungdahl A, Hökfelf T, Jonsson G, Sachs C. Autoradiographic demonstration of uptake and accumulation of 3H-6-hydroxy-dopamine in adrenergic nerves. Experientia 1977;27: 297–299.
- Glinka Y, Gassen M, Youdim MB. Mechanism of 6-hydroxy-dopamine neurotoxicity. J Neural Transm Suppl 1997; 50: 55–66.
- Soto-Otero R, Mendez-Alvarez E, Hermida-Ameijeiras Mufioz-Patillo AM, Labaneira-Garcia JL. Autoxidation and neurotoxicity of 6-hydrodopamine in the presence of some antioxidants:potential implication in relation to the pathogenesis of Parkinson's disease. J Neurochem 2000; 74: 1605–1612.
- Graham D, Tiffany SM, Bell Jr WR, Gutknecht WF. Autoxidation versus covalent binding of quinines as the mechanism of toxicity of dopamine, 6-hydroxydopamine, and related compounds toward C1300 neuroblastoma cells in vitro. Mol Pharmacol 1978; 14: 644–653.
- Mukhtar H, Wang ZY, Katiyar SK, Agarwal R. Tea components: antimutagenic and anticarcinogenic effects. Prey Med 1992; 21: 351–360.
- Wang ZY, Cheng SJ, Zhou ZC et al. Antimutagenic activity of green tea polyphenols. Mutat Res 1989; 223: 273–289.
- Dong ZG, Ma WY, Huang CS, Yang CS. Inhibition of tumor promoter-induced activator protein 1 activation and cell transformation by tea polyphenols, (-)-epigallocatechin gallate and theaflavins. Cancer Res 1997; 57: 4414–4419.
- Nanjo F, Goto K, Seto R, Suzuki M, Sakai M,Hara Y. Scavenging effect of tea catechins and their derivatives on 1,1-dipheny1-2-picrylhydrazyl radical. Free Radic Biol Med 1996; 21: 895–902.
- Sichel G, Corsaro M, Scalia M, DiBilio AJ, Bonomo RP. In vitro scavenger activity of some flavonoids and metanins against 02`. Free Radic Biol Med 1991; 11: 1–8.
- Guo Q, Zhao BL, Li MF, Shen SR, Xin WJ. Studies on protective mechanisms of four components of green tea polyphenols against lipid peroxidation in synaptosomes. Biochim Biophys Acta 1996; 1304: 210–222.
- Inanami 0, Watanabe Y, Syuto B, Nakano M, Tsuji M, Kuwabara M. Oral administration of (-)-catechin protects against ischemia-reperfusion-induced neuronal death in the gerbil. Free Radic Res 1998; 29: 359–365.
- Yoneda T, Hiramatsu M, Skamoto N, Togasaki K, Komatsu M, Yamaguchi K. Antioxidant effects of `13-catechin'. Biochem Mol Biol Int 1995;35: 995–1008.
- Harada J, Sugimoto M. Polyamines prevent apoptotic cell death in cultured granule neurons. Brain Res 1997; 753: 251–259.
- Harfield PJ, Mayne GC, Murray AW. Ceramide induced apoptosis in PC12 cells. FEB S Lett 1997; 401: 148–152.
- Migheli R, Godani C, Sciola L, Delogu R, Serra PA. Enhancing effect of manganese on L-DOPA-induced apoptosis in PC12 cells: role of oxidative stress. J Neurochem 1999; 73: 1155–1163.
- Guo Q, Zhao BL, Hou JW, Xin WJ. ESR study on the structure-antioxidant activity relationship of tea catechins and their epimers. Biochim Biophys Acta 1999; 1427: 13–23.
- Choi WS, Young SY, Oh TH, Choi EJ, Oalley KL, Oh Y. Two distinct mechanisms are involved in 6-hydroxydopamine- and MPPtinduced dopaminergic neuronal cell death: role of caspases, ROS, and JNK. J Neurosci Res 1999; 57: 86–94.
- Yu R, Jiao JJ, Duh JL, Gudehithlu K, Tan TH, Kong AT. Activation of mitogen-activated protein kinases by green tea polyphenols: potential signalling pathway in the regulation of antioxidant-responsive element-mediated phase 11 enzyme gene expression. Carcinogenesis 1997; 18: 451–455.
- Chen C, Yu R, Owuor ED, Kong ANT. Activation of antioxidant-response element (ARE), mitogen-activated protein kinases (MAPKS) and caspases by major green tea polyphenols during cell survival and death. Arch Phann Res 2000; 23: 605–612.
- Nakagawa K, Miyazawa T. Chemiluminescence-high-performance liquid chromatographic determination of tea catechin, (—)-epicatechin 3-gallate, at picomole levels in rat and human plasma. Anal Biochem 1997; 248: 41–49.
- Nakagawa K, Miyazawa, T. Absorption and distribution of tea catechin, (—)-epicatechin 3-gallate, in the rat. J Nutr Sci Vitaminol 1997;43: 679–684.
- Inanami 0, Asanuma T, Inukai N et al. The suppression of age-related accumulation of lipid peroxides in rat brain by administration of rooibos tea. Neurosci Lett 1995; 196: 85–88.
- Levites Y, Weinreb 0, Maor G, Youdim M, Mandel S. Green tea polyphenol (—)-epigallocatechin-3-gallate prevents N-methy1-4-pheny1-1,2,3,6-tetrahydropyidine-induced dopaminergic neurodegeneration. J Neurochem 2001;78: 1073–1082.
- Salah N, Miller NJ, Paganga G, Tijburg L, Bowell GP, Rice-Evans C. Polyphenolicflavonols as scavengers of aqueous phase radicals and as chain-breaking antioxidants. Arch Biochem Biophys 1995; 322: 339–346.
Free access
Protective effects of green tea polyphenols and their major component, (–)-epigallocatechin-3-gallate (EGCG), on 6-hydroxydopamine-induced apoptosis in PC12 cells
Reprints and Corporate Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
To request a reprint or corporate permissions for this article, please click on the relevant link below:
Academic Permissions
Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?
Obtain permissions instantly via Rightslink by clicking on the button below:
If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.
Related research
People also read lists articles that other readers of this article have read.
Recommended articles lists articles that we recommend and is powered by our AI driven recommendation engine.
Cited by lists all citing articles based on Crossref citations.
Articles with the Crossref icon will open in a new tab.