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Short Refereed Papers

Mass spectrometric evidence for long-lived protein adducts of 4-oxo-2-nonenal

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Pages 45-49 | Published online: 19 Jul 2013

REFERENCES

  • Esterbauer H, Schaur RJ, Zollner H. Chemistry and biochemistry of 4-hydroxynonenal, malondialdehyde and related aldehydes. Free Radic Biol Med 1991; 11: 81–128.
  • Uchida K. 4-Hydroxy-2-nonenal: a product and mediator of oxidative stress. Prog Lipid Res 2003; 42: 318–343.
  • Lee SH, Blair IA. Characterization of 4-oxo-2-nonenal as a novel product of lipid peroxidation, Chem Res Toxicol 2000; 13: 698-702.
  • Spiteller P, Kern W, Reiner J, Spiteller G. Aldehydic lipid peroxidation products derived from linoleic acid. Biochim Biophys Acta 2001; 1531: 188–208.
  • Zhang WH, Liu J, Xu G, Yuan Q, Sayre LM. Model studies on protein side chain modification by 4-oxo-2-nonenal. Chem Res Toxicol 2003; 16: 512–523.
  • Lin D, Lee HG, Liu Q, Perry G, Smith MA, Sayre LM. 4-oxo-2-nonenal is both more neurotoxic and more protein reactive than 4-hydroxy-2-nonenal. Chem Res Toxicol 2005; 18: 1219–1231.
  • Doom JA, Petersen DR. Covalent adduction of nucleophilic amino acids by 4-hydroxynonenal and 4-oxononenal. Chembiol Interact 2003; 143/144: 93–100.
  • Doorn JA, Petersen DR Covalent modification of amino acid nucleophiles by the lipid peroxidation products 4-hydroxy-2-nonenal and 4-oxo-2-nonenal. Chem Res Toxicol 2002; 15: 1445–1450.
  • Xu G, Liu Y, Sayre LM. Independent synthesis, solution behavior, and studies on the mechanism of formation of a primary amine-derived fluorophore representing crosslinking of proteins by (E)-4-hydroxy-2-nonenal (FINE). J Org Chem 1999; 64: 5732–5745.
  • Xu G, Sayre LM. Structural characterization of a 4-hydroxy-2-alkenal-derived fluorophore that contributes to lipoperoxidation-dependent protein crosslinking in aging and degenerative disease. Chem Res Toxicol 1998; 11: 247–251.
  • Liu Z, Minlder PE, Sayre LM. Mass spectrometric characterization of protein modification by 4-hydroxy-2-(E)-nonenal and 4-oxo-2-(E)-nonenal. Chem Res Toxicol 2003; 16: 901–911.
  • Oe T, Arora JS Lee SH, Blair IA. A novel lipid hydroperoxide-derived cyclic covalent modification to histone H4. J Biol Chem 2003; 278: 42098–42105.
  • Yocum AK, Oe T, Yergey AL, Blair IA. Novel lipid hydroperoxide-derived hemoglobin histidine adducts as biomarkers of oxidative stress. J Mass Spectrom 2005; 40: 754–764.
  • Yuan, Q. Modification of biomolecules by lipoxidation -derivedaldehydes. PhD Thesis. Case Western Reserve University, Cleveland, OH, USA, 2006.
  • Nadkarni DV, Sayre LM. Structural definition of early lysine and histidine adduction chemistry of 4-hydroxynonenal. Chem Res Toxicol 1995; 8: 284–291.
  • Sayre LM, Lin D, Yuan Q, Zhu X, Tang X. Protein adducts generated from products of lipid oxidation: focus on HNE and ONE. Drug Metab Rev 2006; 38: 651–675.

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