References
- Goldring MB, Goldring SR. Osteoarthritis. J Cell Physiol 2007; 213: 626–634.
- Krasnokutsky S, Samuels J, Abramson SB. Osteoarthritis in 2007. Bull NYU Hosp Joint Dis 2007; 65: 222–228.
- Sharif M, Shepstone L, Elson CJ, Dieppe PA, Kirwan JR. Increased serum C reactive protein may reflect events that precede radiographic progression in osteoarthritis of the knee. Ann Rheum Dis 2000; 59: 71–74.
- Pearle AD, Scanzello CR, George S et al. Elevated high-sensitivity C-reactive protein levels are associated with local inflammatory findings in patients with osteoarthritis. Osteoarthritis Cartilage 2007; 15: 516–523.
- Zhang W, Moskowitz RW, Nuki G et al. OARSI recommendations for the management of hip and knee osteoarthritis, Part II: OARSI evidence-based, expert consensus guidelines. Osteoarthritis Cartilage 2008; 16: 137–162.
- Resch KL, Hill S, Ernst E. Use of complimentary therapies by individuals with ‘arthritis’. Clin Rheumatol 1997; 16: 391–395.
- Farid R, Mirteizi A, Mirheidari M et al. Pycnogenol® supplementation reduces pain and stiffness and improves physical function in adults with knee osteoarthritis. Nutr Res 2007; 27: 692–697.
- Cisár P, Jány R, Waczuliková I et al. Effect of pine bark extract (Pycnogenol®) on symptoms of knee osteoarthritis. Phytother Res 2008; 22: 1087–1092.
- United States Pharmacopeial Convention. United States Pharmacopoeia: Maritime Pine Extract. USP edition 28. Rockville, MD: United States Pharmacopeial Convention, 2005; 2115-2116.
- Kohama T, Suzuki N, Ohno S, Inoue M. Analgesic efficacy of Pycnogenol® in dysmenorrhea. An open clinical trial. J Reprod Med 2004; 49: 828–832.
- Suzuki N, Uebaba K, Kohama T et al. French maritime pine bark extract significantly lowers the requirements for analgesic medication in dysmenorrhea: a multicenter, randomized, double-blind, placebo-controlled study. J Reprod Med 2008; 53: 338–346.
- Kohama T, Herai K, Inoue M. Effect of French maritime pine bark extract on endometriosis as compared to leuprorelin acetate. J Reprod Med 2007; 52: 703–708.
- Belcaro G, Cesarone MR, Errichi Set al. Treatment of osteoarthritis with Pycnogenol®. The SVOS (San Valentino Osteo-arthrosis study). Evaluation of signs, symptoms, physical performance and vascular aspects. Phytother Res 2008; 22: 518–523.
- Cesarone MR, Belcaro G, Nicolaides AN et al. ‘Real’ epidemiology of varicose veins and chronic venous diseases: the San Valentino Vascular Screening Project. Angiology 2002; 53: 119–130.
- Altman R, Asch E, Bloch D et al. Development of criteria for the classification and reporting of osteoarthritis. Classification of osteoarthritis of the knee. Diagnostic and Therapeutic Criteria Committee of the American Rheumatism Association. Arthritis Rheum 1986; 29: 1039–1049.
- Cesarone MR, Belcaro G, Carratelli M, Comelli U, De Sanctis MT. A simple test to monitor oxidative stress. Int Angiol 1999; 18: 127–130.
- Komatsu F, Kagawa Y, Sakuma M et al. Investigation of oxidative stress and dietary habits in Mongolian people, compared to Japanese people. Nutr Metab Land) 2006; 3: 21.
- Rohdewald P, Pycnogenol®, French maritime pine bark extract. In: Coates PM, Blackman MR, Cragg G, Levine M, Moss J, White J. (eds) Encyclopedia of dietary supplements. New York: Marcel Dekker, 2005; 545–253.
- Grimm T, Chovanova Z, Muchova J et al. Inhibition of NF-kB activation and MMP-9 secretion by plasma of human volunteers after ingestion of maritime pine bark extract (Pycnogenol®). J Inflamm 2006; 3: 1–15.
- Schafer A, Chovanova Z, Muchova Jet al. Inhibition of COX-1 and COX-2 activity by plasma of human volunteers after ingestion of French maritime pine bark extract (Pycnogenol®). Biomed Pharmacother 2006; 60: 5–9.
- Grimm T, Schafer A, H8gger P. Antioxidant activity and inhibition of matrix-metalloproteinases by metabolites of maritime pine bark extract (Pycnogenol®). Free Radic Biol Med 2004; 36: 811–822.
- Mold C, Gewurz H, Du Clos TW. Regulation of complement activation by C-reactive protein. Immunopharmacology 1999; 42: 23–30.
- Danesh J. C-reactive protein and other circulating markers of inflammation in the prediction of coronary heart disease. N Engl J Med 2004; 350: 1387–1397.
- Selvin E, Paynter NP, Erlinger TP. The effect of weight loss on C-reactive protein: a systematic review. Arch Intern Med 2007; 167: 31–39.
- Koenig W C-reactive protein - a critical cardiovascular risk marker. Nephrol Dial Transplant 2003; 18: 1039–1041.
- Pepys MB, Hirschfield GM, Tennent GA et al. Targeting C-reactive protein for the treatment of cardiovascular disease. Nature 2006; 440: 1217–1221.
- Cronstein BN. Interleukin-6 - a key mediator of systemic and local symptoms in rheumatoid arthritis. Bull N YU Hosp Joint Dis 2007; 65 (Suppl 1): S11–S15.
- Fisher M, Cushman M, Knappertz V, Howard G. An assessment of the joint associations of aspirin and statin use with C-reactive protein concentration. Am Heart J 2008; 156: 106–111.
- Kakafika AT, Liberopoulos EN, Mikhailidis DP. Fibrinogen: a predictor of vascular disease. Curr Pharm Des 2007; 13: 1647–1659.
- Devaraj S, Vega-Lopez S, Kaul N, Schönlau F, Rohdewald P, Jialal I. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 2002; 37: 931–934.
- Durackova Z, Trebaticky B, Novotny V, Zitnanova A, Breza J. Lipid metabolism and erectile function improvement by Pycnogenol® extract from the bark of Pinus pinaster in patients suffering from erectile dysfunction - a pilot study. Nutr Res 2003; 23: 1189–1198.
- Del Carlo Jr M, Loeser RF. Nitric oxide-mediated chondrocyte cell death requires the generation of additional reactive oxygen species. Arthritis Rheum 2002; 46: 394–403.