Overexpression of Prdx6 and resistance to peroxide-induced death in Hepa1-6 cells: Prdx suppression increases apoptosis

References

• Halliwell B, Gutteridge J. Free Radicals in Biology and Medicine, 3rd edn. New York: Oxford University Press, 1999.
   Google Scholar
• Immenschuh S, Baumgart-Vogt E. Peroxiredoxins, oxidative stress, and cell proliferation. Antioxid Redox Signal 2005; 7: 768–777.
   PubMed Web of Science ®Google Scholar
• Hofmann B, Hecht HJ, Flohe L. Peroxiredoxins. Biol Chem 2002; 383: 347–364.
   PubMed Web of Science ®Google Scholar
• Rhee SG, Chae HZ, Kim K. Peroxiredoxins: a historical overview and speculative preview of novel mechanisms and emerging concepts in cell signaling. Free Radic Biol Med 2005; 38: 1543–1552.
   PubMed Web of Science ®Google Scholar
• Cross C, Halliwell B, Borish E et al. Oxygen radicals and human disease. Ann Intern Med 1987; 107: 526–545.
   PubMed Web of Science ®Google Scholar
• Sun A, Chen Y. Oxidative stress and neurodegenerative disorders. J Biomed Sci 1998; 5: 401–414.
   PubMed Web of Science ®Google Scholar
• Gius D, Spitz D. Redox signaling in cancer biology. Antioxid Redox Signal 2006; 8: 1249–1252.
   PubMed Web of Science ®Google Scholar
• Noh DY, Ahn SJ, Lee RA, Kim SW, Park IA, Chae HZ. Overexpression of peroxiredoxin in human breast cancer. Anticancer Res 2001; 21: 2085–2090.
   PubMed Web of Science ®Google Scholar
• Kinnula VL, Lehtonen S, Sormunen R et al. Overexpression of peroxiredoxins I, II, III, V, and VI in malignant mesothelioma. J Pathol 2002; 196: 316–323.
   PubMed Web of Science ®Google Scholar
• Karihtala P, Mantyniemi A, Kang SW, Kinnula VL, Soini Y. Peroxiredoxins in breast carcinoma. Clin Cancer Res 2003; 15: 3418–3424.
   Google Scholar
• Lehtonen ST, Svensk AM, Soini Y et al. Peroxiredoxins, a novel protein family in lung cancer. Int J Cancer 2004; 111: 514–521.
   PubMed Web of Science ®Google Scholar
• Quan C, Cha EJ, Lee HL, Han KH, Lee KM, Kim WJ. Enhanced expression of peroxiredoxin I. and V. I. Correlates with development recurrence and progression of human bladder cancer. J Urol 2006; 175: 1512–1516.
   PubMed Web of Science ®Google Scholar
• Chang XZ, Li DQ, Hou YF et al. Identification of the functional role of peroxiredoxin 6 in the progression of breast cancer. Breast Cancer Res 2007; 9: R76.
   PubMed Web of Science ®Google Scholar
• Butterfield LH, Merino A, Golub SH, Shau H. From cytoprotection to tumor suppression: the multifactorial role of peroxiredoxins. Antioxid Redox Signal 1999; 1: 385–402.
   PubMed Web of Science ®Google Scholar
• Kinnula VL, Paakko P, Soini Y Antioxidant enzymes and redox regulating thiol proteins in malignancies of human lung. FEBS Lett 2004; 569: 1–6.
   PubMed Web of Science ®Google Scholar
• Neumann CA, Fang Q. Are peroxiredoxins tumor suppressors? Curr Opin Pharmacol 2007; 7: 375–380.
   PubMed Web of Science ®Google Scholar
• Manevich Y, Fisher AB. Peroxiredoxin 6, a 1-Cys peroxiredoxin, functions in antioxidant defense and lung phospholipid metabolism. Free Radic Biol Med 2005; 38: 1422–1432.
   PubMed Web of Science ®Google Scholar
• Manevich Y, Sweitzer T, Pak JH, Feinstein SI, Muzykantov V, Fisher AB. 1-Cys peroxiredoxin overexpression protects cells against phospholipid peroxidation-mediated membrane damage. Proc Natl Acad Sci USA 2002; 99: 11599–11604.
   PubMed Web of Science ®Google Scholar
• Phelan SA, Wang X, Wallbrandt P, Forsman-Semb K, Paigen B. Overexpression of peroxiredoxin VI reduces H202 but does not prevent diet-induced atherosclerosis. Free Radic Biol Med 2003; 35: 1110–1120.
   PubMed Web of Science ®Google Scholar
• Wang Y, Manevich Y, Feinstein SI, Fisher AB. Adenovirus-mediated transfer of the 1-Cys peroxiredoxin gene to mouse lung protects against hyperoxic injury. Am J Physiol 2004; 286: L1188–L1193.
   PubMed Web of Science ®Google Scholar
• Wang Y, Phelan SA, Manevich Y, Feinstein SI, Fisher AB. Transgenic mice overexpressing peroxiredoxin 6 show increased resistance to lung injury in hyperoxia. Am J Respir Cell Mol Biol 2006; 34: 481–486.
   PubMed Web of Science ®Google Scholar
• Wang Y, Feinstein S, Fisher A. Peroxiredoxin 6 as an antioxidant enzyme: protection of lung alveolar epithelial type II cells from H202-induced oxidative stress. J Cell Biochem 2008; 104: 1274–1285.
   PubMed Web of Science ®Google Scholar
• Pak JH, Manevich Y, Kim HS, Feinstein SI, Fisher AB. An antisense oligonucleotide to 1-Cys peroxiredoxin causes lipid peroxidation and apoptosis in lung epithelial cells. J Biol Chem 2002; 277: 49927–49934.
   PubMed Web of Science ®Google Scholar
• Wang X, Phelan SA, Forsman-Semb K et al. Mice with targeted mutation of peroxiredoxin 6 develop normally but are susceptible to oxidative stress. J Biol Chem 2003; 278: 25179–25190.
   PubMed Web of Science ®Google Scholar
• Kumin A, Huber C, Rulicke T, Wolf E, Werner S. Peroxiredoxin 6 is a potent cytoprotective enzyme in the epidermis. Epithel Mesenchym Cell Biol 2006; 169: 1194–1205.
   Google Scholar
• Wang Y, Feinstein SI, Manevich Y, Ho YS, Fisher AB. Peroxiredoxin 6 gene-targeted mice show increased lung injury with paraquat induced oxidative stress. Antioxid Redox Signal 2006; 8: 229–237.
   PubMed Web of Science ®Google Scholar
• Sparling N, Phelan SA. Identification of multiple transcripts for antioxidant protein 2 (A0P2): differential regulation by oxidative stress and growth factors. Redox Reports 2003; 8: 87–94.
   PubMed Web of Science ®Google Scholar
• Gallagher BM, Phelan SA. Transcriptional regulation of peroxiredoxin 6 in mouse liver cells. Free Radic Biol Med 2007; 42: 1270–1277.
   PubMed Web of Science ®Google Scholar
• Livak K, Schmittgen T. Analysis of relative gene expression data using real-time quantitative PCR and the 26,ACT method. Methods Enzymol 2001; 25: 402–408.
   Web of Science ®Google Scholar
• Gardiner F, Gaynor P, Phelan SA. Induction of Prdxl and Prdx6 in liver cells by serum and TPA. Int J Biol 2010; 2: In press.
   Google Scholar
• Gu S, Villegas C, Jiang J. Differential regulation of amino acid transporter SNAT3 by insulin in hepatocytes. J Biol Chem 2005; 280: 26055–26062.
   PubMed Web of Science ®Google Scholar
• Hasty A, Shimano H, Yahagi N et al. Sterol regulatory element-binding protein-1 is regulated by glucose at the transcriptional level. J Biol Chem 2000; 275: 31068–31077.
   Google Scholar
• Lora J, Rowader K, Soares L, Giancotti F, Zaret K. Alpha3betal-integrin as a critical mediator of the hepatic differentiation response to the extracellular matrix. Hepatology 1998; 28: 1095–1104.
   PubMed Web of Science ®Google Scholar
• Sass G, Leukel P, Schmitz V et al. Inhibition of heme oxygenase 1 expression by small interfering RNA decreases orthotopic tumor growth in livers of mice. Int J Cancer 2008; 123: 1269–1277.
   PubMed Web of Science ®Google Scholar
• Herold C, Ganslmayer M, Ocker M, Hermann M, Hahn E, Schuppan D. Combined in vitro anti-tumoral action of tamoxifen and retinoic acid derivatives in hepatoma cells. Int J Oncol 2002; 20: 89–96.
   PubMed Web of Science ®Google Scholar
• Conde de la Rosa L, Schoemaker M, Vrenken T et al. Superoxide anions and hydrogen peroxide induce hepatocyte death by different mechanisms: involvement of JNK and ERK MAP kinases. J Hepatol 2006; 44: 918–929.
   PubMed Web of Science ®Google Scholar
• Saberi B, Shinohara M, Ybanez M et al. Regulation of H(2)0(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes. Am J Physiol 2008; 295: C50–C63.
   Web of Science ®Google Scholar
• Fujita Y, Nakanishi T, Hiramatsu M et al. Proteomics-based approach identifying autoantibody against peroxiredoxin VI as a novel serum marker in esophageal squamous cell carcinoma. Clin Cancer Res 2006; 12: 6415–6420.
   PubMed Web of Science ®Google Scholar
• Safe S, Abdelrahim M. Sp transcription factor family and its role in cancer. Eur J Cancer 2005; 41: 2438–2448.
   PubMed Web of Science ®Google Scholar
• Neumann CA, Krause DS, Carman CV. Essential role for the peroxiredoxin Prdxl in erythrocyte antioxidant defense and tumour suppression. Nature 2003; 424: 561–565.
   PubMed Web of Science ®Google Scholar
• Cao J, Schulte J, Knight A et al. Prdxl inhibits tumorigenesis via regulating PTEN/AKT activity. EMBO J2009; 28: 1505-1517.
   Google Scholar
• Ouyang X, DeWeese TL, Nelson WG, Abate-Shen C. Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis. Cancer Res 2005; 65: 6773–6779.
   PubMed Web of Science ®Google Scholar