Publication Cover
Redox Report
Communications in Free Radical Research
Volume 21, 2016 - Issue 1
701
Views
5
CrossRef citations to date
0
Altmetric
Original Articles

Creatine supplementation decreases plasma lipid peroxidation markers and enhances anaerobic performance in rats

&

References

  • Harris RC, Söderlund K, Hultman E. Elevation of creatine in resting and exercised muscle of normal subjects by creatine supplementation. Clin Sci (Lond) 1992;83:367–74.
  • Wyss M, Schulze A. Health implications of creatine: can oral creatine supplementation protect against neurological and atherosclerotic disease. Neuroscience 2002;112:243–60.
  • Bender A, Koch W, Elstner M, Schombacher Y, Bender J, Moeschl M, et al. Creatine supplementation in Parkinson disease: a placebo-controlled randomized pilot trial. Neurology 2006;67:1262–4.
  • Gualano B, Artioli GG, Poortmans JR, Lancha Junior AH. Exploring the therapeutic role of creatine supplementation. Amino Acids 2010;38:31–44.
  • Kley RA, Tarnopolsky MA, Vorgerd M. Creatine for treating muscle disorders. Cochrane Database Syst Rev 2011;16:CD004760.
  • Gualano B, Salles PV, Roschel H, Artioli GG, Neves MJr, Sá De, et al. Creatine in type 2 diabetes: a randomized, double-blind, placebo-controlled trial. Med Sci Sports Exerc 2011;43:770–8.
  • Deminice R, da Silva RP, Lamarre SG, Brown C, Furey GN, McCarter SA, et al. Creatine supplementation prevents the accumulation of fat in the livers of rats fed a high-fat diet. J Nutr 2011;141:1799–804.
  • Gualano B, Roschel H, Lancha-Jr AH, Brightbill CE, Rawson ES. In sickness and in health: the widespread application of creatine supplementation. Amino Acids 2012;43:519–29.
  • Sestili P, Martinelli C, Colombo E, Barbieri E, Potenza L, Sartini S, et al. Creatine as an antioxidant. Amino Acids 2011;40:1385–96.
  • Lawler JM, Barnes WS, Wu G, Song W, Demaree S. Direct antioxidant properties of creatine. Biochem Biophys Res Commun 2002;290:47–52.
  • Lenz H, Schmidt M, Welge V, Schlattner U, Wallimann T, Elsässer HP, et al. The creatine kinase system in human skin: protective effects of creatine against oxidative and UV damage in vitro and in vivo. J Invest Dermatol 2005;124:443–52.
  • Sestili P, Martinelli C, Bravi G, Piccoli G, Curci R, Battistelli M, et al. Creatine supplementation affords cytoprotection in oxidatively injured cultured mammalian cells via direct antioxidant activity. Free Radic Biol Med 2006;40:837–49.
  • Fimognari C, Sestili P, Lenzi M, Cantelli-Forti G, Hrelia P. Protective effect of creatine against RNA damage. Mutat Res 2009;670:59–67.
  • Guidi C, Potenza L, Sestili P, Martinelli C, Guescini M, Stocchi L, et al. Differential effect of creatine on oxidatively-injured mitochondrial and nuclear DNA. Biochim Biophys Acta 2008;1780:16–26.
  • Deminice R, Portari GV, Vannucchi H, Jordao AA. Effects of creatine supplementation on homocysteine levels and lipid peroxidation in rats. Br J Nutr 2009;102:110–6.
  • Deminice R, Jordao AA. Creatine supplementation reduces oxidative stress biomarkers after acute exercise in rats. Amino Acids 2012;43:709–15.
  • Reeves PG, Nielsen FH, Fahey GC. AIN-93 purified diets for laboratory rodents: final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76A rodent diet. J Nutr 1993;123:1939–51.
  • Shimojo N, Naka K, Uenoyama H, Hamamoto K, Yoshioka K, Okuda K. Electrohemical assay system with single-use electrode strip for measuring lactate in whole blood. Clin Chem 1993;39:2312–2314. 17.
  • Roßkopf P, Lamprecht W, Liesen H. The Accusport® analyzer and its operation. In: Ramstetter E, Zieres-Nauth C, Mack M (eds.) Workshop report Accusport®. Zürich 1994-03-18. Mannheim: Boehringer; 1995. p. 33–6.
  • Deminice R, Vannucchi H, Simões-Ambrosio LM, Jordao AA. Creatine supplementation reduces increased homocysteine concentration induced by acute exercise in rats. Eur J Appl Physiol 2011;111:2663–70.
  • Spirlandeli AL, Deminice R, Jordao AA. Plasma malondialdehyde as biomarker of lipid peroxidation: effects of acute exercise. Int J Sports Med 2014;35:14–8, 2014.
  • Costa CM, Dos Santos RCC, Lima E. A simple automated procedure for thiol measurement in human and serum samples. Braz J Pathol Med Lab 2006;42:345–350.
  • Witko-Sarsat V, Friedlander M, Capeillère-Blandin C, Nguyen-Khoa T, Nguyen AT, Zingraff J, et al. Advanced oxidation protein products as a novel marker of oxidative stress in uremia. Kidney Int 1996;49:1304–13.
  • Rahman I, Kode A, Biswas SK. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nat Protoc 2006;1(6):3159–65.
  • Dill DB, Costill DL. Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 1974;37:247–8.
  • Bloomer RJ, Falvo MJ, Fry AC, Schilling BK, Smith WA, Moore CA. Oxidative stress response in trained men following repeated squats or sprints. Med Sci Sports Exerc 2006;38:1436–42.
  • Finaud J, Lac G, Filaire E. Oxidative stress: relationship with exercise and training. Sports Med 2006;36:327–58.
  • Bloomer RJ. Effect of exercise on oxidative stress biomarkers. Adv Clin Chem 2008;46:1–50.
  • Banerjee AK, Mandal A, Chanda D, Chakraborti S. Oxidant, antioxidant and physical exercise. Mol Cell Biochem 2003;253:307–12.
  • Guimarães-Ferreira L, Pinheiro CH, Gerlinger-Romero F, Vitzel KF, Nachbar RT, Curi R, et al. Short-term creatine supplementation decreases reactive oxygen species content with no changes in expression and activity of antioxidant enzymes in skeletal muscle. J Appl Physiol 2012;112:3913.
  • Young JF, Larsen LB, Malmendal A, Nielsen NC, Straadt IK, Oksbjerg N, et al. Creatine-induced activation of antioxidative defence in myotube cultures revealed by explorative NMR-based metabonomics and proteomics. J Int Soc Sports Nutr 2010;7:9.
  • Meyer LE, Machado LB, Santiago AP, da-Silva WS, De Felice FG, Galina A. Mitochondrial creatine kinase activity prevents reactive oxygen species generation: antioxidant role of mitochondrial kinase-dependent ADP re-cycling activity. J Biol Chem 2006;281:37361–71.
  • Santiago AP, Chaves EA, Oliveira MF, Galina A. Reactive oxygen species generation is modulated by mitochondrial kinases: correlation with mitochondrial antioxidant peroxidases in rat tissues. Biochimie 2008;90:1566–77.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.