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Redox Report
Communications in Free Radical Research
Volume 21, 2016 - Issue 3
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Original Articles

What if cell culture media do not mimic in vivo redox settings?

References

  • Ganz T, Nemeth E. Hepcidin and disorders of iron metabolism. Annu Rev Med 2011;62:347–60. doi: 10.1146/annurev-med-050109-142444
  • Cavill I, Staddon G, Jacobs A. Iron kinetics in the skin of patients with iron overload. J Invest Dermatol 1972;58(2):96–8. doi: 10.1111/1523-1747.ep12551708
  • Kakuta K, Orino K, Yamamoto S, Watanabe K. High levels of ferritin and its iron in fetal bovine serum. Comp Biochem Physiol A Physiol 1997;118(1):165–69. doi: 10.1016/S0300-9629(96)00403-3
  • Wesselius LJ, Williams WL, Bailey K, Vamos S, O'Brien-Ladner AR, Wiegmann T. Iron uptake promotes hyperoxic injury to alveolar macrophages. Am J Respir Crit Care Med 1999;159(1):100–6. doi: 10.1164/ajrccm.159.1.9801033
  • Halliwell B. Oxidative stress in cell culture: an under-appreciated problem? FEBS Lett 2003;540(1–3):3–6. doi: 10.1016/S0014-5793(03)00235-7
  • Halliwell B. Cell culture, oxidative stress, and antioxidants: avoiding pitfalls. Biomed J 2014;37(3):99–105.
  • Parrow NL, Leshin JA, Levine M. Parenteral ascorbate as a cancer therapeutic: a reassessment based on pharmacokinetics. Antioxid Redox Sign 2013;19(17):2141–56. doi: 10.1089/ars.2013.5372
  • Mojić M, Bogdanović Pristov J, Maksimović-Ivanić D, Jones DR, Stanić M, Mijatović S, Spasojević I. Extracellular iron diminishes anticancer effects of vitamin C: an in vitro study. Sci Rep 2014;4:5955. doi: 10.1038/srep05955
  • Chen Q, Espey MG, Krishna MC, Mitchell JB, Corpe CP, Buettner GR, et al. Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues. Proc Natl Acad Sci USA 2005;102(38):13604–9. doi: 10.1073/pnas.0506390102
  • Hempel SL, Buettner GR, Wessels DA, Galvan GM, O'Malley YQ. Extracellular iron (II) can protect cells from hydrogen peroxide. Arch Biochem Biophys 1996;330(2):401–8. doi: 10.1006/abbi.1996.0268
  • Taqui Khan MM, Martell AE. Metal ion and metal chelate catalyzed oxidation of ascorbic acid by molecular oxygen. I. Cupric and ferric ion catalyzed oxidation. J Am Chem Soc 1967;89(16):4176–85. doi: 10.1021/ja00992a036
  • Du J, Wagner BA, Buettner GR, Cullen JJ. The role of labile iron in the toxicity of pharmacological ascorbate. Free Radic Biol Med 2015;88:289–95. doi: 10.1016/j.freeradbiomed.2015.03.033
  • Long LH, Clement MV, Halliwell B. Artifacts in cell culture: rapid generation of hydrogen peroxide on addition of (–)-epigallocatechin, (–)-epigallocatechin gallate, (+)-catechin, and quercetin to commonly used cell culture media. Biochem Biophys Res Commun 2000;273(1):50–3. doi: 10.1006/bbrc.2000.2895
  • Long LH, Kirkland D, Whitwell J, Halliwell B. Different cytotoxic and clastogenic effects of epigallocatechin gallate in various cell-culture media due to variable rates of its oxidation in the culture medium. Mutat Res 2007;634(1–2):177–83. doi: 10.1016/j.mrgentox.2007.07.009
  • Carocho M, Ferreira IC. The role of phenolic compounds in the fight against cancer – a review. Anticancer Agents Med Chem 2013;13(8):1236–58. doi: 10.2174/18715206113139990301

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