The effect of high glucose on SERT, the human plasmalemmal serotonin transporter

References

• Blakely RD, Berson HE, Fremeau RT, et al. Cloning and expression of a functional serotonin transporter from rat brain. Nature 1991; 354: 66–70.
   PubMed Web of Science ®Google Scholar
• Hoffman B, Mezey E, Brownstein M. Cloning of a serotonin transporter affected by antidepressants. Science 1991; 254: 579–580.
   PubMed Web of Science ®Google Scholar
• Chang AS, Chang SM, Starnes DM, Schroeter S, Bauman AL, Blakely RD. Cloning and expression of the mouse serotonin transporter. Mol Brain Res 1996; 43: 185–192.
   PubMedGoogle Scholar
• Mortensen OV, Kristensen AS, Rudnick G, Wiborg O. Molecular cloning, expression and characterization of a bovine serotonin transporter. Brain Res Mol Brain Res 1999; 71: 120–126.
   PubMedGoogle Scholar
• Ramamoorthy S, Bauman AL, Moore KR, et al. Antidepressant- and cocaine-sensitive human serotonin transporter: molecular cloning, expression and chromosomal localization. Proc Natl Acad Sci USA 1993; 90: 2542–2546.
   PubMed Web of Science ®Google Scholar
• Blakely RD, De Felice LJ, Hartzell HC. Molecular physiology of norepinephrine and serotonin transporters. J Exp Biol 1994; 196: 263–281.
   PubMed Web of Science ®Google Scholar
• Gainetdinov RR, Caron MG. Monoamine transporters: from genes to behavior. Annu Rev Pharmacol Toxicol 2003; 43: 261–284.
   PubMed Web of Science ®Google Scholar
• Iversen L. Neurotransmitter transporters and their impact on the development of psychopharmacology. Br J Pharmacol 2006; 147 (Suppl 1): S82–S88.
   PubMed Web of Science ®Google Scholar
• Coates MD, Mahoney CR, Linden DR, et al. Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome. Gastroenterology 2004; 26: 1657–1664.
   Google Scholar
• Mokrovic G, Matosic A, Hranilovic D, et al. Alcohol dependence and polymorphisms of serotonin-related genes: association studies. Coll Antropol 2008; 32 (Suppl 1): 127–131.
   PubMedGoogle Scholar
• Katsuyama H, Tomita M, Hidaka K, et al. Association between serotonin transporter gene polymorphisms and depressed mood caused by job stress in Japanese workers. Int J Mol Med 2008; 21: 499–505.
   PubMed Web of Science ®Google Scholar
• Zaboli G, Jönsson EG, Gizatullin R, De Franciscis A, Asberg M, Leopardi R. Haplotype analysis confirms association of the serotonin transporter (5-HT) gene with schizophrenia but not with major depression. Am J Med Genet B Neuropsychiatr Genet 2008; 147: 301–307.
   PubMedGoogle Scholar
• King H, Aubert RE, Herman WH. Global burden of diabetes, 1995–2025: prevalence, numerical estimates, and projections. Diabetes Care 1998; 21: 1414–1431.
   PubMed Web of Science ®Google Scholar
• Wild S, Roglic G, Green A, Sicree R, King H. Global prevalence of diabetes. Estimates for the year 2000 and projections for 2030. Diabetes Care 2004; 27: 1047–1053.
   PubMed Web of Science ®Google Scholar
• Sesti G. Pathophysiology of insulin resistance. Best Pract Res Clin Endocrinol Metab 2006; 20: 665–679.
   PubMed Web of Science ®Google Scholar
• Thomson AB, Wild G. Adaptation of intestinal nutrient transport in health and disease. Part II. Dig Dis Sci 1997; 42: 470–488.
   PubMed Web of Science ®Google Scholar
• Contreras R, Fuentes O, Mann GE, Sobrevia L. Diabetes and insulin-induced stimulation of L-arginine transport and nitric oxide synthesis in rabbit isolated gastric glands. J Physiol 1997; 498: 787–796.
   PubMed Web of Science ®Google Scholar
• Casirola DM, Vinnakota RR, Ferraris RP. Intestinal amino acid transport in mice is modulated by diabetes and diet. J Nutr 1994; 124:842–852.
   PubMed Web of Science ®Google Scholar
• Adibi SA. Regulation of expression of the intestinal oligopeptide transporter (Pept-1) in health and disease. Am J Physiol 2003; 285: G779 -G788.
   PubMed Web of Science ®Google Scholar
• Carratu R, Secondulfo M, de Magistris L, et al. Altered intestinal permeability to mannitol in diabetes mellitus type I. J Pediatr Gastroenterol Nutr 1999; 28: 264–269.
   PubMed Web of Science ®Google Scholar
• Basu TK, Basualdo C. Vitamin A homeostasis and diabetes mellitus. Nutrition 1997; 13: 804–806.
   PubMed Web of Science ®Google Scholar
• Schedl HP, Christensen KK, Ronnenberg WC. Effects of diabetes on calcium uptake by rat brush border membrane vesicles. Clin Exp Pharmacol Physiol 1995; 22: 272–276.
   PubMed Web of Science ®Google Scholar
• Naggar H, Ola MS, Moore P, et al. Downregulation of reduced- folate transporter by glucose in cultured RPE cells and in RPE of diabetic mice. Invest Ophthalmol Vis Sci 2002; 43: 556–563.
   PubMed Web of Science ®Google Scholar
• Faria A, Monteiro R, Azevedo I, Calhau C. Extracellular glucose concentration alters hEMT expression in Caco-2 cells. Acta Biomed 2006; 77 (Suppl 3): 62
   Google Scholar
• Delie F, Rubas W. A human colonic cell line sharing similarities with enterocytes as a model to examine oral absorption: advantages and limitations of the Caco-2 model. Crit Rev Ther Drug Carr Syst 1997; 14: 221–286.
   PubMed Web of Science ®Google Scholar
• Martel F, Monteiro R, Lemos C. Uptake of serotonin at the apical and basolateral membranes of human intestinal epithelial (Caco-2) cells occurs through the neuronal serotonin transporter (SERT). J Pharmacol Exp Ther 2003; 306: 355–362.
   PubMed Web of Science ®Google Scholar
• Bradford MM. A rapid method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 1976; 72: 248–254.
   PubMed Web of Science ®Google Scholar
• Motulsky HJ, Spannard P, Neubig R. Graphpad Prism, version 1.0. San Diego, CA: Graphpad Prism Software, 1994.
   Google Scholar
• Unal R, Ahmed BA, Jeffus BC, et al. At diabetes-like concentration, glucose down-regulates the placental serotonin transport system in a cell-cycle-dependent manner. JNeurochem 2007; 101: 937–948.
   PubMed Web of Science ®Google Scholar
• Martel F, Gonçalves P, Azevedo I. Absorption of folate by Caco-2 cells is not affected by high glucose concentration. Eur J Pharmacol 2006; 551: 19–26.
   PubMed Web of Science ®Google Scholar
• Jacob RJ, Fan X, Evans ML, Dziura J, Sherwin RS. Brain glucose levels are elevated in chronically hyperglycemic diabetic rats: no evidence for protective adaptation by the blood brain barrier. Metabolism 2002; 51: 1522–1524.
   PubMed Web of Science ®Google Scholar
• Gregg EW, Yaffe K, Cauley JA, et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Arch Intern Med 2000; 160: 174–180.
   PubMed Web of Science ®Google Scholar
• Padbury JF, Tseng YT, McGonnigal B, Penado K, Stephan M, Rudnick G. Placental biogenic amine transporters: cloning and expression. Brain Res Mol Brain Res 1997; 45: 163–168.
   PubMedGoogle Scholar
• Nguyen TT, Tseng YT, McGonnigal B, et al. Placental biogenic amine transporters: in vivo function, regulation and pathobiological significance. Placenta 1999; 20: 3–11.
   PubMed Web of Science ®Google Scholar
• Ganapathy V, Prasad PD, Ganapathy ME, Leibach FH. Placental transporters relevant to drug distribution across the maternal-fetal interface. J Pharmacol Exp Ther 2000; 294: 413–420.
   PubMed Web of Science ®Google Scholar
• Ganapathy V, Leibach FH. Human placenta: a direct target for cocaine action. Placenta 1994; 15: 785–795.
   PubMed Web of Science ®Google Scholar
• Ganapathy V, Prasad PD, Ganapathy ME, Leibach FH. Drugs of abuse and placental transport. Adv Drug Deliv Rev 1999; 38: 99–110.
   PubMed Web of Science ®Google Scholar
• Gershon MD. Roles played by 5-hydroxytryptamine in the physiology of the bowel. Aliment Pharmacol Ther 1999; 13 (Suppl 2): 15–30.
   PubMed Web of Science ®Google Scholar