Early iron deficiency produces persistent damage to visual tracts in Wistar rats

References

• Yager JY, Hartfield DS. Neurologic manifestations of iron deficiency in childhood. Pediatr Neurol 2002; 27: 85–92.
   PubMed Web of Science ®Google Scholar
• Stoltzfus RJ. Defining iron-deficiency anemia in public health terms: a time for reflection. J Nutr 2001; 131: 565S-567S.
   PubMed Web of Science ®Google Scholar
• Beard JL. Iron biology in immune function, muscle metabolism and neuronal functioning. J Nutr 2001; 131: 568S-579S.
   PubMed Web of Science ®Google Scholar
• Conrad ME, Umbreit JN, Moore EG. Iron absorption and transport. Am J MedSci 1999; 318: 213–229.
   PubMed Web of Science ®Google Scholar
• Beard JL, Connor JR, Jones BC. Iron in the brain. Nutr Rev 1993; 51: 157–170.
   PubMed Web of Science ®Google Scholar
• Lin HH, Connor JR. The development of the transferrin-transferrin receptor system in relation to astrocytes, MBP and galacto- cerebroside in normal and myelin-deficient rat optic nerves. Dev Brain Res 1989; 49: 281–293.
   PubMedGoogle Scholar
• Moos T, Morgan EH. A morphological study of the developmentally regulated transport of iron into the brain. Dev Neurosci 2002; 24: 99–105.
   PubMed Web of Science ®Google Scholar
• Connor JR, Menzies SL, Burdo JR, Boyer PJ. Iron and iron management proteins in neurobiology. PediatrNeurol2001; 25:118–129.
   Google Scholar
• Sanyal B, Polak PE, Szuchet S. Differential expression of the heavy- chain ferritin gene in non-adhered and adhered oligodendrocytes. J Neurosci Res 1996; 46: 187–197.
   PubMed Web of Science ®Google Scholar
• Lakhanpal V, Schocket SS, Rouben J. Deferoxamine (Desferal®)- induced toxic retinal pigmentary degeneration and presumed optic neuropathy. Ophthalmology 1984; 91: 443–451.
   PubMed Web of Science ®Google Scholar
• Olivieri NF, Buncic JR, Chew E, et al. Visual and auditory neurotoxicity in patients receiving subcutaneous deferoxamine infusions. N Engl J Med 1986; 314: 869–873.
   PubMed Web of Science ®Google Scholar
• Sarici SU, Okutan V, Dundaroz MR, et al. The effect of iron supplementation on visual-evoked potentials in infants with iron- deficiency anemia. J Tropical Pediatr 2001; 47: 132–135.
   PubMed Web of Science ®Google Scholar
• Friel JK, Aziz K, Andrews WL, Harding SV, Courage ML, Adams RJ. A double-masked, randomized control trial of iron supplementation in early infancy in healthy term breast-fed infants. J Pediatr 2003; 143: 582–586.
   PubMed Web of Science ®Google Scholar
• Lozoff B, De Andraca I, Castillo M, Smith JB, Walter T, Pino P. Behavioral and developmental effects of preventing iron-deficiency anemia in healthy full-term infants. Pediatrics 2003; 112: 846–854.
   PubMed Web of Science ®Google Scholar
• Beard JL, Connor JR. Iron status and neural functioning. Annu Rev Nutr 2003; 23:41–48.
   PubMed Web of Science ®Google Scholar
• Pinero D, Jones B, Beard JL. Variations in dietary iron alter behavior in developing rats. J Nutr 2001; 131: 311–318.
   PubMed Web of Science ®Google Scholar
• Pinero DJ, Li NQ, Connor JR, Beard JL. Alterations in brain iron metabolism in response to dietary iron changes. J Nutr 2000; 130: 254–263.
   PubMed Web of Science ®Google Scholar
• Beard JL, Erikson KM, Jones BC. Neurobehavioral analysis of developmental iron deficiency in rats. Behav Brain Res 2002; 134: 517–524.
   PubMed Web of Science ®Google Scholar
• Beard JL, Felt B, Schallert T, Burhans M, Connor JR, Georgieff MK. Moderate iron deficiency in infancy: biology and behavior in young rats. Behav Brain Res 2006; 170: 224–232.
   PubMed Web of Science ®Google Scholar
• Beard JL, Wiesinger JA, Connor JR. Pre- and post weaning iron deficiency alters myelination in Sprague-Dawley rats. Dev Neurosci 2003; 25: 308–315.
   PubMed Web of Science ®Google Scholar
• Scott TM, Foote J. The postnatal development of blood vessels in the optic nerve of normotensive and hypertensive rats. J Anat 1984; 138: 635–642.
   PubMed Web of Science ®Google Scholar
• De Juan J, Iniguez C, Carreres J. Number, diameter and distribution of the rat optic nerve fibers. Acta Anat (Basel) 1978; 102: 294–299.
   PubMedGoogle Scholar
• Fukui Y, Hayasaka S, Bedi KS, Ozaki HS, Takeuchi Y. Quantitative study of the development of the optic nerve in rats reared in the dark during early postnatal life. JAnat 1991; 174: 37–37.
   Google Scholar
• Butt AM, Pugh M, Hubbard P, James G. Functions of optic nerve glia: axoglial signalling in physiology and pathology. Eye 2004; 18: 1110–1121.
   PubMed Web of Science ®Google Scholar
• Wiggins RC, Fuller GN, Brizzee L, Bissel AC, Samorajski T. Myelination of the rat optic nerve during postnatal undernourishment and recovery: a morphometric analysis. Brain Res 1984; 308: 263–272.
   PubMed Web of Science ®Google Scholar
• Gong H, Amemiya T. Optic nerve changes in manganese-deficient rats. Exp Eye Res 1999; 68: 313–320.
   PubMed Web of Science ®Google Scholar
• Gong H, Amemiya T. Optic nerve changes in zinc-deficient rats. Exp Eye Res 2001; 72: 363–369.
   PubMed Web of Science ®Google Scholar
• Algarin C, Peirano P, Garrido M, Pizarro F, Lozoff B. Iron deficiency anemia in infancy: long-lasting effects on auditory and visual system functioning. Pediatr Res 2003; 53: 217–223.
   PubMed Web of Science ®Google Scholar
• Cunnif P. Official methods of analysis of AOAC International. In: Association of Official Analytical Chemists International, 16th edn. Washington, DC: AOAC, 1995; 58–63.
   Google Scholar
• Dallman PR, Siimes MA, Manies EC. Brain iron: persistent deficiency following short-term iron deprivation in the young rat. Br JHaematol 1975; 31: 209–215.
   PubMed Web of Science ®Google Scholar
• Tanaka M, Kariya F, Kaihatsu K, et al. Effects of chronic iron deficiency anemia on brain metabolism. Jpn J Physiol 1995; 45: 257–263.
   PubMedGoogle Scholar
• de los Monteros AE, Korsak RA, Tran T, Vu D, de Vellis J, Edmond J. Dietary iron and the integrity of the developing rat brain: a study with the artificially-reared rat pup. CellMolBiol 2000; 46: 501–515.
   Web of Science ®Google Scholar
• O’Connor DL, Picciano MF, ShermanAR. Impact of maternal iron deficiency on quality and quantity of milk ingested by neonatal rats. Br JNutr 1988; 60: 477–485.
   PubMed Web of Science ®Google Scholar
• Dobbing J. Undernutrition and the developing brain. The relevance of animal models to the human problem. Biblio Nutr Diet 1992; 17: 35–36.
   Google Scholar
• Dangata YY, Findlater GS, Kaufman MH. Postnatal development of the optic nerve in (C57BL x CBA)F1 hybrid mice: general changes in morphometric parameters. J Anat 1996; 189: 117–125.
   PubMed Web of Science ®Google Scholar
• Dake Y, Amemiya T. Electron microscopic study of the optic nerve in copper deficient rats. Exp Eye Res 1991; 52: 277–281.
   PubMed Web of Science ®Google Scholar
• Cavallotti C, Cavallotti D, Pescosolido N, Pacella E. Age-related changes in rat optic nerve: morphological studies. Anat Histol Embryol 2003; 32: 12–16.
   PubMed Web of Science ®Google Scholar
• Sandell JH, Peters A. Effects of age on nerve fibers in the Rhesus monkey optic nerve. J Comp Neurol 2001; 429: 541–553.
   PubMed Web of Science ®Google Scholar