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Nutritional Neuroscience
An International Journal on Nutrition, Diet and Nervous System
Volume 16, 2013 - Issue 6
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Original research papers

Asparagus racemosus modulates the hypothalamic–pituitary–adrenal axis and brain monoaminergic systems in rats

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Pages 255-261 | Published online: 15 Nov 2013

References

  • Dahanukar SA, Kulkarni RA, Rege NN. Pharmacology of medicinal plants and natural products. Indian J Pharmacol 2000;32:S81–118.
  • Muruganandam AV, Kumar V, Bhattacharya SK. Effect of poly herbal formulation, EuMIl, on chronic stress-induced homeostatic pertubations in rats. Indian J Exp Biol 2002;40:1151–60.
  • Goyal RK, Singh J, Lal H. Asparagus racemosus – an update. Indian J Med Sci 2003;57:408–14.
  • Hayes PY, Jahidin AH, Lehmann R, Penman K, Kitching W, De Voss JJ. Steroidal saponins from the roots of Asparagus racemosus. Phytochemistry 2008;69:796–804.
  • Satti NK, Suri KA, Dutta P, Suri OP, Amina M, Qazi GN, et al. Evaluation of Asparagus racemosus on the basis of immunomodulating sarsasapogenin glycosides by HPTLC. J Liquid Chromatogr Relat Technol 2006;29:219–27.
  • Singh GK, Garabadu D, Muruganandam AV, Joshi VK, Krishnamurthy S. Antidepressant activity of Asparagus racemosus in rodent models. Pharmacol Biochem Behav 2009;91:283–90.
  • Ojha R, Sahu AN, Muruganandam AV, Singh GK, Krishnamurthy S. Asparagus recemosus enhances memory and protects against amnesia in rodent models. Brain Cogn 2010;74:1–9.
  • Meena J, Ojha R, Muruganandam AV, Krishnamurthy S. Asparagus racemosus competitively inhibits in vitro the acetylcholine and monoamine metabolizing enzymes. Neurosci Lett 2011;503:6–9.
  • Sharma PC, Yelne MB, Dennis TJ. Database on medicinal plants used in Ayurveda, Volume I. Central Council for Research in Ayurveda and Siddha. New Delhi: Yugantar Prakashan (P.) Ltd; 2000. p. 418–30.
  • Sairam K, Priyambada S, Aryya NC, Goel RK. Gastroduodenal ulcer protective activity of Asparagus racemosus: an experimental, biochemical and histological study. J Ethnopharmacol 2003;86:1–10.
  • Bhattacharya SK, Bhattacharya A, Sairam K, Ghosal S. Anxiolytic-antidepressant activity of Withania somnifera glycowithanolides: an experimental study. Phytomedicine 2000;7:463–9.
  • Garabadu D, Shah A, Ahmad A, Joshi VB, Saxena B, Palit G, et al. Eugenol as an anti-stress agent: modulation of hypothalamic-pituitary-adrenal axis and brain monoaminergic systems in a rat model of stress. Stress 2011;14:145–55.
  • Irwin S, Slabok M, Debiase PL, Govier WM. Perphenazine (trilafon), a new potent tranquilzer and antiemetic. I. Behavioral mode of action. Arch Int Pharmacodyn Ther 1959;118(3–4):358–74.
  • Karl T, Pabst R, von Hörsten S. Behavioral phenotyping of mice in pharmacological and toxicological research. Exp Toxicol Pathol 2003;55(1):69–83.
  • Lowry OH, Rosenborough NJ, Farr AL, Randall RJ. Protein measurement with folin phenol reagent. J Biol Chem 1951;193:265–75.
  • Stratakis CA, Chrousos GP. Neuroendocrinology and pathophysiology of the stress system. Ann N Y Acad Sci 1995;771:1–18.
  • Dronjak S, Spasojevic N, Gavrilovic L, Varagic V. Effects of noradrenaline and serotonin reuptake inhibitors on pituitary-adrenocortical and sympatho-adrenomedullar system of adult rats. Neuro Endocrinol Lett 2007;28:614–20.
  • Elftman MD, Hunzeker JT, Mellinger JC, Bonneau RH, Norbury CC, Truckenmiller ME. Stress-induced glucocorticoids at the earliest stages of herpes simplex virus-1 infection suppress subsequent antiviral immunity, implicating impaired dendritic cell function. J Immunol 2010;184:1867–75.
  • Hellevuo K, Kiianmaa K, Juhakoski A. Effects of barbital and lorazepam in the AT and ANT rats: motor performance and brain monoamine functions. Alcohol Alcohol Suppl 1987;1:647–51.
  • Charney DS, Deutch A. A functional neuroanatomy of anxiety and fear: implications for the pathophysiology and treatment of anxiety disorders. Crit Rev Neurobiol 1996;10:419–46.
  • Kent JM, Coplan JD, Gorman JM. Clinical utility of the selective serotonin reuptake inhibitors in the spectrum of anxiety. Biol Psychiatry 1998;44:812–24.
  • Graeff FG, Guimarães FS, De Andrade TG, Deakin JF. Role of 5-HT in stress, anxiety, and depression. Pharmacol Biochem Behav 1996;54:129–41.
  • Debiec J, Ledoux JE. Disruption of reconsolidation but not consolidation of auditory fear conditioning by noradrenergic blockade in the amygdala. Neuroscience 2004;129:267–72.
  • Wise RA, Rompre PP. Brain dopamine and reward. Annu Rev Psychol 1989;40:191–225.
  • Morilak DA, Barrera G, Echevarria J, Garcia AS, Hernandez A, Ma S, et al. Role of brain norepinephrine in the behavioral response to stress. Prog Neuropsychopharmacol Biol Psychiatry 2005;29:1214–24.

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